The present invention relates to the field of ultrasounds and imagining of the coronary blood flow of the heart. Patients with coronary microvascular dysfunction (CMD) have poor prognostic with significantly higher rates of cardiovascular events, including hospitalization for heart failure, sudden cardiac death, and myocardial infarction (MI). Despite the urgent clinical need, there are no non-ionizing and non-invasive techniques available in clinic to directly visualize the coronary microvasculature and assess the local coronary microvascular system. Flow imaging remains a difficult task to perform in the heart because of the fast movements of this organ. In order to overcome the limitations of actual imaging methods for the coronary blood flow, the inventors proposed an ultrasound ultrafast imaging method that automatically detect the time periods in which the myocardium velocity is low and estimate the coronary flow velocity and the tissue velocity from the same data acquisition.

The present invention related to an ultrasound imaging system win which the scan head includes a beamformer circuit that performs far field subarray beamforming or includes a sparse array selecting circuit that actuates selected elements. When using a hierarchical two-stage or three-stage beamforming system, three dimensional ultrasound images can be generated in real-time. The invention further relates to flexible printed circuit boards in the probe head. The invention furthermore related to the use of coded or spread spectrum signaling in ultrasound imagining systems. Matched filters based on pulse compression using Golay code pairs improve the signal-to-noise ratio thus enabling third harmonic imaging with suppressed sidelobes. The system is suitable for 3D full volume cardiac imaging.

An imaging system includes transmit circuitry, a transducer array with an array of capacitive micromachined ultrasonic transducer elements, a beamformer, a decoder and a display. The transmit circuitry includes a signal generator and at least one excitation coding scheme. The transmit circuitry combines an excitation signal generated by the signal generator with an excitation coding scheme of the at least one excitation coding scheme, generating a coded excitation signal. The array of transducer elements is excited with the coded excitation signal to emit ultrasound signals. The coding scheme does not introduce heating on the capacitive micromachined ultrasonic transducer elements. The array of ultrasonic transducer elements receives echo signals produced in response to the ultrasound signals interacting with structure and generates electrical signals indicative thereof. The beamformer beamforms the electrical signals, the decoder removes the coding from the beamformed signals, and the display displays an image with the decoded signals.

Techniques for operating an ultrasonic sensor array, the ultrasonic sensor array disposed under a platen, include making a determination whether or not to recalibrate the ultrasonic sensor array based on whether a first screen protector disposed above the platen has been removed or replaced by a second screen protector; and recalibrating the ultrasonic sensor array, when the determination is to recalibrate the ultrasonic sensor array. In some cases, the techniques include prompting a user to indicate whether or not the screen protector has been changed or removed, and recalibrating the ultrasonic sensor array only after confirmation from the user.

Multifunctional ultrasound systems and methods for body section registration and mapping of microbubble dynamics. A system is provided that includes one or more micromachined ultrasonic transducer arrays (MUTAs) configured to capture a high-resolution image of at least a portion of a body section using ultrasound and monitor microbubble activity during ultrasound treatment. The system includes an image registration module configured to spatially register the high-resolution image with a reference image. The system includes electronics configured to control one or more of drive signal amplitude, frequency filtering, multiplexing, and DC bias voltage. The system can be configured to control ultrasound treatment based on the monitoring of the microbubble activity during treatment.

Methods and systems for ultrasound imaging and beamforming with a matrix array of transducer elements are provided. Receive signals of each transducer array element are amplified. The amplified receive signal of each transducer array element is digitized. A delay and weight are applied on the amplified and digitized receive signals. The amplified, digitized, delayed, and weighted receive signals are summed across all transducer elements of the matrix array to form a dynamically focused receive beam. An application specific integrated circuit (ASIC) that is integrated with the matrix array of transducer elements performs such steps.

According to one embodiment, an ultrasound diagnostic apparatus includes a transmitter/receiver and processing circuitry. The transmitter/receiver sequentially transmits a first transmission beam group and a second transmission beam group and receives at least one reception beam for each transmission beam, via an ultrasound probe having a plurality of transducers arranged along an azimuth direction and an elevation direction. The processing circuitry combines a first reception beam based on a first transmission beam included in the first transmission beam group and a second reception beam based on a second transmission beam included in the second transmission beam group. Transmission beams that are adjacent to each other in the azimuth direction or the elevation direction belong to transmission beam groups that are different from each other.

According to examples, systems, devices, and methods for detecting rapid eye movement (REM) are described. The device may include an array of ultrasound sensors oriented to emit transmit ultrasounds signals in an eyeward direction, wherein the ultrasound sensors are to receive a return signal of the transmit signal reflecting off of a target, and wherein the ultrasound sensors are to output a distance signal representative of a distance to a target, the distance signal generated based on the return signal, and a transceiver to receive the distance signals, wherein the transceiver is to transmit the distance signals from the array of ultrasound sensors to a remote device.

A medical system includes an ultrasound probe configured for insertion into an organ of a body, and a processor. The probe includes a two-dimensional (2D) ultrasound transducer array, and a sensor configured to output signals indicative of a position, direction and orientation of the 2D ultrasound transducer array inside the organ. The processor is configured to (a) using the signals output by the sensor, register multiple ultrasound images of a tissue region, acquired over a given time duration by the 2D ultrasound transducer array, with one another, (b) estimate, based on the ultrasound images acquired over the given time duration, three-dimensional displacements as a function of time for one or more locations in the tissue region, (c) estimate respective mechanical strains of the one or more locations in the tissue region, based on the three-dimensional displacements, and (d) present a time-dependent rendering of the mechanical strains to a user.

A medical system includes an ultrasound probe for insertion into an organ of a body and a processor. The ultrasound probe includes (i) a two-dimensional (2D) ultrasound transducer array, and (ii) a sensor configured to output signals indicative of a position, direction and orientation of the 2D ultrasound transducer array inside the organ. The processor is configured to (a) using the signals output by the sensor, register multiple ultrasound images of a tissue region, acquired over a given time duration by the 2D ultrasound transducer array, with one another, and (b) generate a map of the tissue region indicative of respective amounts of motion of tissue locations in the tissue region.