Described herein are systems and methods for positioning a radiation source with respect to one or more regions of interest in a coordinate system. Such systems and methods may be used in emission guided radiation therapy (EGRT) for the localized delivery of radiation to one or more patient tumor regions. These systems comprise a gantry movable about a patient area, where a plurality of positron emission detectors, a radiation source are arranged movably on the gantry, and a controller. The controller is configured to identify a coincident positron annihilation emission path and to position the radiation source to apply a radiation beam along the identified emission path. The systems and methods described herein can be used alone or in conjunction with surgery, chemotherapy, and/or brachytherapy for the treatment of tumors.

The present invention refers to a method for determining a position of a divergent radiation source (1), comprising Irradiating a pixel detector (2) with a predetermined intensity distribution of radiation with wavelength λ originated from the radiation source (1), wherein the pixel detector (2) comprises a plurality of pixels with pixel coordinates (x.sub.i, y.sub.i, z.sub.i); Detecting, for each of the plurality of pixels, an intensity of the incident radiation (10); Determining, for each of the plurality of pixels, an incidence direction of the incident radiation using information on an orientation of an internal periodic structure at the pixel and the predetermined intensity distribution, wavelength λ and the detected intensity; and Determining the position (x.sub.p, y.sub.p, z.sub.p) of the radiation source (1) using the pixel coordinates (x.sub.i, y.sub.i, z.sub.i) and the incidence direction for each of the plurality of pixels. The invention further refers to a system, a computer-related product and a sample (8) for performing such method and to the use of a pixel detector (2) for determining a position of a divergent radiation source (1)

A system and method for imaging by gamma radiation detection having at least one processing unit analyzing at least one signal provided by at least one set of detection modules mounted on a frame and including, on the one hand, at least one module of Compton camera type having a field of view directed towards a volume delimited by the frame and, on the other hand, at least one pair of coincidence detection PET modules, diametrically opposite to each other on the frame and defining an imaging axis, the processing unit analyzing the signal derived from the Compton-type module to determine the intersection of the imaging axis with the field of view and to determine the optimal orientations and/or locations of the various detection modules on the frame so that the imaging axis passes through the source of the gamma radiation in the object to be imaged.

A system for directional detection of radiation, comprises a plurality of scintillating crystals, responsive to the radiation and being arranged three-dimensionally, with voids between adjacent crystals, such that there are crystals that are inner and crystals that are outer within the arrangement. The system also comprises a plurality of light sensors coupled to the crystals for receiving optical signals from the crystals and responsively generating electrical signals, and a data processor receiving an electrical signal separately from each light sensor and calculating a direction of the radiation based on relative intensities of the signals and mutual occultation among different crystals.

Various techniques are provided to detect the direction and location of one or more radiation sources. In one example, a system includes a plurality of radiation detectors configured to receive radiation from a radiation source. A first one of the radiation detectors is positioned to at least partially occlude a second one of the radiation detectors to attenuate the radiation received by the second radiation detector. The system also includes a processor configured to receive detection information provided by the first and second radiation detectors in response to the radiation, and determine a direction of the radiation source using the detection information. A modular system including gamma radiation detectors and neutron radiation detectors and related methods are also provided. In some cases, radiation source type may be determined in addition to or separate from radiation source direction.

In one embodiment, a charged-particle trajectory measurement apparatus for measuring a trajectory of a cosmic ray muon as a charged particle includes: a plurality of detectors, each of which generates a detection signal at the time of detecting a cosmic ray muon; a signal processing circuit that processes the detection signal from the detector; a time calculator that calculates the generation time point of the detection signal from the detector on the basis of the signal outputted from the signal processing circuit; a trajectory calculator that calculates the trajectory of the cosmic ray muon on the basis of the generation time point of the detection signal and the positional information of the detector having detected the cosmic ray muon, wherein the signal processing circuit and each of the detectors are integrally configured by being coupled to each other.

The present disclosure provides a gamma ray imaging device and an imaging method, where the imaging device includes a plurality of separate detectors. The plurality of separate detectors are provided at an appropriate spatial position, in an appropriate arrangement manner and are of an appropriate detector material, such that when rays emitted from different positions in an imaging area reach at least one of the plurality of separate detectors, at least one of the thicknesses of the detectors, the materials of the detectors, and the numbers of the detectors though which the rays pass are different, thereby achieving the effect of determining the directions of rays.

A radiation diagnostic device according to an aspect of the present invention includes a first detector, a second detector, and processing circuitry. The first detector detects Cherenkov light that is generated when radiation passes. The second detector is disposed to be opposed to the first detector on a side distant from a generation source of the radiation, and detects energy information of the radiation. The processing circuitry specifies Compton scattering events detected by the second detector, and determines an event corresponding to an incident channel among the specified Compton scattering events based on a detection result obtained by the first detector.

Techniques are disclosed for systems and methods using silicon photomultiplier (SiPM) based radiation detectors to detect radiation in an environment. An SiPM-based radiation detection system may include a number of detector assemblies, each including at least one scintillator providing light to a corresponding SiPM in response to ionizing radiation entering the scintillator. The radiation detection system may include a logic device and a number of other electronic modules to facilitate reporting, calibration, and other processes. The logic device may be adapted to process detection signals from the SiPMs to implement different types of radiation detection procedures. The logic device may also be adapted to use a communication module to report detected radiation to an indicator, a display, and/or a user interface.

A direction determination device for determining a direction of a source of ionizing radiation relative to the direction determination device includes at least two radiation detection devices with longitudinally designed detection volumes, the at least two radiation detection devices are arranged at an angle relative to one another. A first radiation detection device is designed as a symmetry-maintaining angle-dependent radiation detection device. A second radiation detection device is designed as a symmetry-breaking angle-dependent radiation detection device.