A system for optimizing a machine learning model. The machine learning model generates predictions based on at least one input feature vector, each input feature vector having one or more vector values; and an optimization module with a processor and an associated memory, the optimization module being configured to: create at least one slice of the predictions based on at least one vector value, determine at least one optimization metric of the slice that is based on at least a total number of predictions for the vector value, and optimize the machine learning model based on the optimization metric.

An IDS generator determines multiple classes for electronic data items. The IDS generator determines, for each class, a class-specific candidate ruleset. The IDS generator performs a differential analysis of each class-specific candidate ruleset. The differential analysis is based on differences between result values of a scoring objective function. In some cases, the differential analysis determines at least one of the differences based on additional data structures, such as an augmented frequent-pattern tree. A probability function based on the differences is compared to a threshold probability At least one testing ruleset is modified based on the comparison. The IDS generator determines, for each class, a class-specific optimized ruleset based on the differential analysis of each class-specific candidate ruleset. The IDS generator creates an optimized interpretable decision set based on combined class-specific optimized rulesets for the multiple classes.

An IDS generator determines multiple classes for electronic data items. The IDS generator determines, for each class, a class-specific candidate ruleset. The IDS generator performs a differential analysis of each class-specific candidate ruleset. The differential analysis is based on differences between result values of a scoring objective function. In some cases, the differential analysis determines at least one of the differences based on additional data structures, such as an augmented frequent-pattern tree. A probability function based on the differences is compared to a threshold probability At least one testing ruleset is modified based on the comparison. The IDS generator determines, for each class, a class-specific optimized ruleset based on the differential analysis of each class-specific candidate ruleset. The IDS generator creates an optimized interpretable decision set based on combined class-specific optimized rulesets for the multiple classes.

Methods for generating data models using a generative adversarial network can begin by receiving a data model generation request by a model optimizer from an interface. The model optimizer can provision computing resources with a data model. As a further step, a synthetic dataset for training the data model can be generated using a generative network of a generative adversarial network, the generative network trained to generate output data differing at least a predetermined amount from a reference dataset according to a similarity metric. The computing resources can train the data model using the synthetic dataset. The model optimizer can evaluate performance criteria of the data model and, based on the evaluation of the performance criteria of the data model, store the data model and metadata of the data model in a model storage. The data model can then be used to process production data.

Methods for generating data models using a generative adversarial network can begin by receiving a data model generation request by a model optimizer from an interface. The model optimizer can provision computing resources with a data model. As a further step, a synthetic dataset for training the data model can be generated using a generative network of a generative adversarial network, the generative network trained to generate output data differing at least a predetermined amount from a reference dataset according to a similarity metric. The computing resources can train the data model using the synthetic dataset. The model optimizer can evaluate performance criteria of the data model and, based on the evaluation of the performance criteria of the data model, store the data model and metadata of the data model in a model storage. The data model can then be used to process production data.

Methods, systems, and devices for automated feature selection and model generation are described. A device (e.g., a server, user device, database, etc.) may perform model generation for an underlying dataset and a specified outcome variable. The device may determine relevance measurements (e.g., stump R-squared values) for a set of identified features of the dataset and can reduce the set of features based on these relevance measurements (e.g., according to a double-box procedure). Using this reduced set of features, the device may perform a least absolute shrinkage and selection operator (LASSO) regression procedure to sort the features. The device may then determine a set of nested linear models—where each successive model of the set includes an additional feature of the sorted features—and may select a “best” linear model for model generation based on this set of models and a model quality criterion (e.g., an Akaike information criterion (AIC)).

Methods, systems, and devices for automated feature selection and model generation are described. A device (e.g., a server, user device, database, etc.) may perform model generation for an underlying dataset and a specified outcome variable. The device may determine relevance measurements (e.g., stump R-squared values) for a set of identified features of the dataset and can reduce the set of features based on these relevance measurements (e.g., according to a double-box procedure). Using this reduced set of features, the device may perform a least absolute shrinkage and selection operator (LASSO) regression procedure to sort the features. The device may then determine a set of nested linear models—where each successive model of the set includes an additional feature of the sorted features—and may select a “best” linear model for model generation based on this set of models and a model quality criterion (e.g., an Akaike information criterion (AIC)).

A system and method for analyzing a data store of de-identified patient data to generate one or more dynamic user interfaces usable to predict an expected response of a particular patient population or cohort when provided with a certain treatment. The automated analysis of patterns occurring in patient clinical, molecular, phenotypic, and response data, as facilitated by the various user interfaces, provides an efficient, intuitive way for clinicians to evaluate large data sets to aid in the potential discovery of insights of therapeutic significance.

A system and method for analyzing a data store of de-identified patient data to generate one or more dynamic user interfaces usable to predict an expected response of a particular patient population or cohort when provided with a certain treatment. The automated analysis of patterns occurring in patient clinical, molecular, phenotypic, and response data, as facilitated by the various user interfaces, provides an efficient, intuitive way for clinicians to evaluate large data sets to aid in the potential discovery of insights of therapeutic significance.

A method includes generating first contrast significance data for a first computer vision model generated from a first training set of medical scans. First significant contrast parameters are identified based on the first contrast significance data. A first re-contrasted training set is generated based on performing a first intensity transformation function on the first training set of medical scans, where the first intensity transformation function utilizes the first significant contrast parameters. A first re-trained model is generated from the first re-contrasted training set, which is associated with corresponding output labels based on abnormality data for the first training set of medical scans. Re-contrasted image data of a new medical scan is generated based on performing the first intensity transformation function. Inference data indicating at least one abnormality detected in the new medical scan is generated based on utilizing the first re-trained model on the re-contrasted image data.