Various methods and systems are provided for computed tomography imaging. In one embodiment, a method includes acquiring, with an x-ray detector and an x-ray source coupled to a gantry, a three-dimensional image volume of a subject while the subject moves through a bore of the gantry and the gantry rotates the x-ray detector and the x-ray source around the subject, inputting the three-dimensional image volume to a trained deep neural network to generate a corrected three-dimensional image volume with a reduction in aliasing artifacts present in the three-dimensional image volume, and outputting the corrected three-dimensional image volume. In this way, aliasing artifacts caused by sub-sampling may be removed from computed tomography images while preserving details, texture, and sharpness in the computed tomography images.

A multi-color quantitative magnetic nanoparticle imaging method and system based on trapezoidal wave excitation solves the problem that the existing technology cannot implement multi-color quantitative magnetic particle imaging. The method includes: constructing, based on hysteresis effect and hysteresis inertial growth differences of n superparamagnetic iron oxide nanoparticles (SPIOs) under trapezoidal wave excitation, an equation set of quality of n SPIOs in a to-be-tested sample formed by any composition of n SPIO standard products; solving the equation set to obtain the quality distribution of the to-be-tested sample at position r; and performing rearrangement, color assignment, and image merging on the quality distribution to implement multi-color quantitative imaging of various particles in magnetic particle imaging (MPI). The method broadens the functions of MPI to realize multi-color quantitative imaging, such that MPI has greater potential for application in the medical field.

Various methods and systems are provided for artifact reduction with resolution preservation. In one example, a method includes obtaining projection data of an imaging subject, identifying a metal-containing region in the projection data, interpolating the metal-containing region to generate interpolated projection data, extracting high frequency content information from the projection data in the metal-containing region, adding the extracted high frequency content information to the interpolated projection data to generate adjusted projection data, and reconstructing one or more diagnostic images from the adjusted projection data.

The present disclosure provides systems and methods for hybrid imaging. The systems and methods may obtain a first magnetic resonance (MR) image of a target object. The first MR image may be acquired by a magnetic resonance imaging (MRI) device using a first imaging sequence. The systems and methods may also obtain a second MR image of the target object. The second MR image may be acquired by the MRI device using a second imaging sequence. The second MR image may correspond to a target respiratory phase of the target object. The systems and methods may also obtain a target emission computed tomography ECT) image of the target object. The target ECT image may correspond to the target respiratory phase. The systems and methods may further fuse, based on the second MR image, the first MR image and the target ECT image.

A system and method for estimating vascular flow using CT imaging include a computer readable storage medium having stored thereon a computer program comprising instructions, which, when executed by a computer, cause the computer to acquire a first set of data comprising anatomical information of an imaging subject, the anatomical information comprises information of at least one vessel. The instructions further cause the computer to process the anatomical information to generate an image volume comprising the at least one vessel, generate hemodynamic information based on the image volume, and acquire a second set of data of the imaging subject. The computer is also caused to generate an image comprising the hemodynamic information in combination with a visualization based on the second set of data.

The apparatus for an X-ray data generation according to an embodiment of the inventive concept includes a processor that receives 3D data to generate output data and a buffer, and the processor includes an extraction unit that extracts raw object data from the 3D data and projects the raw object data onto a 2D plane to generate first object data, an augmentation unit that performs data augmentation on the first object data to generate second object data, a composition unit that synthesizes the second object data and background data to generate composite data, and a post-processing unit that performs post-processing on the composite data to generate the output data, and the buffer stores a plurality of parameters related to generation of the first object data, the second object data, the composite data, and the output data.

Disclosed are a system, method, and computer program product for generating pruned tractograms of neural fiber bundles. The method includes receiving scan data produced by diffusion imaging of at least a portion of a brain from a magnetic-resonance imaging (MRI) device. The method also includes generating an initial tractogram by mapping neuronal fiber pathways of a target fiber bundle of the scan data. The method further includes generating a density map using a set of tracts from the initial tractogram, identifying each tract that passes through a segment of the density map more than once, and setting a contribution of said tract to a unique tract count of the segment equal to a threshold pruning value. The method further includes generating a pruned tractogram by identifying a segment having a unique tract count less than or equal to the threshold pruning value and excluding the segment from the pruned tractogram.

The present invention discloses a clustering algorithm-based multi-parameter cumulative calculation method for lower limb vascular calcification indexes, including the following steps: firstly carrying out super-pixel segmentation of a CT image, and enabling calcified spots in the CT image to be segmented in each super-pixel region; after the super-pixel segmentation is accomplished, extracting a brightness characteristic value of a super-pixel region where the calcified spots are located by using a Lab color space, and performing edge detection and contour extraction on the calcified spots in the image; and after edge detection and contour extraction, fitting the calcified spots in the image by using a segmented ellipse, and extracting the area of the calcified spots after optimizing an ellipse contour.

A method for compensating motion in positron emission tomographic, PET, data comprising coincident lines of response from positron-emitting position markers, includes: detecting a slippage of one or more of the position markers; determining slippage correction parameters based on the detected slippage; and applying motion correction to the PET data by taking into account the slippage correction parameters, thereby obtaining a motion-compensated PET data.

Systems and methods for reconstructing medical images are disclosed. Measurement data from positron emission tomography (PET) data, and measurement data from an anatomy modality, such as magnetic resonance (MR) data or computed tomography (CT) data, is received from an image scanning system. A PET image is generated based on the PET measurement data, and an anatomy image is generated based on the anatomy measurement data. A trained neural network is applied to the PET image and the anatomy image to generate an attenuation map. The neural network may be trained based on anatomy and PET images. In some examples, the trained neural network generates an initial attenuation map based on the anatomy image, registers the initial attenuation map to the PET image, and generates an enhanced attenuation map based on the registration. Further, a corrected image is reconstructed based on the generated attenuation map and the PET image.