This application disclosures a method and system for detecting a centerline of a vessel. The method may include obtaining image data, wherein the image data may include vessel data; selecting two endpoints of the vessel based on the vessel data; transforming the image data to generate a transformed image based on at least one image transformation function; and determining a path of the centerline of the vessel connecting the first endpoint of the vessel and the second endpoint of the vessel to obtain the centerline of the vessel based on the transformed image. The two endpoints of the vessel may include a first endpoint of the vessel and a second endpoint of the vessel.

A method for performing a computer-aided diagnosis (CAD) includes: acquiring a medical image set; generating a three-dimensional (3D) tumor distance map corresponding to the medical image set, each voxel of the tumor distance map representing a distance from the voxel to a nearest boundary of a primary tumor present in the medical image set; and performing neural-network processing of the medical image set to generate a predicted probability map to predict presence and locations of oncology significant lymph nodes (OSLNs) in the medical image set, wherein voxels in the medical image set are stratified and processed according to the tumor distance map.

This application disclosures a method and system for detecting a centerline of a vessel. The method may include obtaining image data, wherein the image data may include vessel data; selecting two endpoints of the vessel based on the vessel data; transforming the image data to generate a transformed image based on at least one image transformation function; and determining a path of the centerline of the vessel connecting the first endpoint of the vessel and the second endpoint of the vessel to obtain the centerline of the vessel based on the transformed image. The two endpoints of the vessel may include a first endpoint of the vessel and a second endpoint of the vessel.

One example provides a computing system comprising a depth sensor comprising a plurality of pixels, and a storage machine holding instructions executable by a logic machine to, for each pixel, make K phase measurements to form a set of noisy phase measurements, determine a location at which a projection line that passes through the set of noisy phase measurements in a K-dimensional phase space passes through a lower dimensional plane, the projection line being parallel to a noise free phase evolution line, compare the location to a plurality of independent terms of a predetermined matrix of points in the lower dimensional plane, locate a corresponding set of noiseless phase orders by using a selected set of independent terms to reference a look-up table, determine a distance value for the pixel based upon the corresponding set of noiseless phase orders, and output the distance value for the pixel.

A method and a device for the characterization of living specimens from a distance are disclosed. The method comprises: acquiring an image of a living specimen and segmenting the image, providing a segmented image; measuring a distance to several parts of said image, providing several distance measurements, and selecting a subset of those contained in the segmented image. The method also processes the segmented image and the distance measurements referred to different positions contained within the segmented image by characterizing the shape and the depth of the living specimen and by comparing a shape analysis map and a depth profile analysis map. If a result of the comparison is comprised inside a given range, parameters of the living specimen are further determined including posture parameters, location or correction of anatomical reference points and/or body size parameters, and/or a body map of the living specimen is represented.

A computer-implemented method comprising: receiving a 3D image including an object depicted in the image, the 3D image comprising an ordered set of 2D images; determining a contour around the object in a first of said 2D images; and determining a contour around the object in a second of said 2D images, the second 2D image being non-contiguous with the first in said ordered set, having an intermediate region comprising one or more intermediate ones of said 2D images between the first and second 2D images within said ordered set. In each of the first and second 2D images, inside of the contour is classified as foreground and outside of the contour is classified as background. The method further comprises performing a 3D geodesic distance computation to classify points in the intermediate region as foreground of background.

The disclosure relates to a method for determining a boundary about an area of interest in an image set. The includes obtaining the image set from an imaging modality and processing the image set in a convolutional neural network. The convolutional neural network is trained to perform the acts of predicting an inverse distance map for the actual boundary in the image set; and deriving the boundary from the inverse distance map. The disclosure also relates to a method of training a convolutional neural network for use in such a method, and a medical imaging arrangement.

Systems and methods related to combing multiple images are disclosed. An example method of combining multiple images of a body structure includes capturing a first input image with a digital camera positioned at a first location at a first time point, representing the first image with a first plurality of pixels, capturing a second input image with the digital camera positioned at a second location at a second time point, representing the second image with a second plurality of pixels, generating a first feature distance map of the first input image, generating a second feature distance map of the second input image, calculating the positional change of the digital camera between the first time point and the second time point and utilizing the first feature distance map, the second feature distance map and the positional change of the digital camera to generate a three-dimensional surface approximation the body structure.

The method for determining property feature segmentation includes: receiving a region image for a region; determining parcel data for the region; determining a final segmentation output based on the region image and parcel data using a trained segmentation module; optionally generating training data; and training a segmentation module using the training data S500.

Techniques are provided for determining a cell count within a whole slide pathology image. The image is segmented using a global threshold value to define a tissue area. A plurality of patches comprising the tissue area are selected. Stain intensity vectors are determined within the plurality of patches to generate a stain intensity image. The stain intensity image is iteratively segmented to generate a cell mask using a local threshold value that is and gradually reduced after each iteration. A chamfer distance transform is applied to the cell mask to generate a distance map. Cell seeds are determined on the distance map. Cell segments are determined using a watershed transformation, and a whole cell count is calculated for the plurality of patches based on the cell segments. A client device may be configured for real-time cell counting based on the whole cell count.