Risk prediction models are trained and deployed to analyze images, such as computed tomography scans, for predicting risk of lung cancer (e.g., current or future risk of lung cancer) for one or more subjects. Individual risk prediction models are trained on nodule-specific and non-nodule specific features, including longitudinal nodule specific and longitudinal non-nodule specific features, such that each risk prediction model can predict risk of lung cancer across different time horizons. Such risk prediction models are useful for developing preventive therapies for lung cancer by enabling clinical trial enrichment.

A Computer Aided Diagnosis, CADx, system (200) is described that comprises: at least one input (210, 212, 214) configured to provide at least one input medical image; and a CADx processing engine (220) configured to receive and process the at least one input medical image and produce at least one CADx score. A CADx score mapping circuit is operably coupled to the CADx processing engine (220) and configured to: map the at least one CADx score to a risk adjusted virtual score; and generate an output (235) of at least the risk adjusted virtual score associated with the processed at least one input medical image. The at least one CADx score and the risk adjusted virtual score correspond to an equivalent risk of condition or disease associated with a patient.

An X-ray imaging system using multiple puked X-ray sources to perform highly efficient and ultrafast 3D radiography is presented. There are multiple puked X-ray sources mounted on a structure in motion to form an array of sources. The multiple X-ray sources move simultaneously relative to an object on a pre-defined arc track at a constant speed as a group. Electron beam inside each individual X-ray tube is deflected by magnetic or electrical field to move focal spot a small distance. When focal spot of an X-ray tube beam has a speed that is equal to group speed but with opposite moving direction, the X-ray source and X-ray flat panel detector are activated through an external exposure control unit so that source tube stay momentarily standstill equivalently. 3D scan can cover much wider sweep angle in much shorter time and image analysis can also be done in real-time.

A local extension method for segmentation of anatomical treelike structures includes receiving an initial segmentation of 3D image data including an initial treelike structure. A target point in the 3D image data is defined, and a region of interest based on the target point is extracted to create a sub-image. Highly tubular voxels are detected in the sub-image, and a spillage-constrained region growing is performed using the highly tubular voxels as seed points. Connected components are extracted from the results of the region growing. The extracted components are pruned to discard components not likely to be connected to the initial treelike structure, keeping only candidate components likely to be a valid sub-tree of the initial treelike structure. The candidate components are connected to the initial treelike structure, thereby extending the initial segmentation in the region of interest.

Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) are commonly used to assess patients with known or suspected pathologies of the lungs and liver. In particular, identification and quantification of possibly malignant regions identified in these high-resolution images is essential for accurate and timely diagnosis. However, careful quantitative assessment of lung and liver lesions is tedious and time consuming. This disclosure describes an automated end-to-end pipeline for accurate lesion detection and segmentation.

An information processing apparatus including at least one processor, wherein the at least one processor is configured to: derive a property score indicating a prominence of a property for each of predetermined property items from at least one image; and derive, for each of the property items, a description score indicating a degree of recommendation for including a description regarding the property item in a document.

An image processing apparatus, an image display system, an image processing method, and a program by which it is possible to grasp, on a screen for observing a given low-dimensional image having a lower level of dimensions than a medical image, information of the low-dimensional image in which a region of interest is present and information of the region of interest. A medical image including two or more low-dimensional images (102) is acquired, region-of-interest information representing information of a region of interest (108) automatically detected from the medical image is acquired for each of the low-dimensional images, axis information (104) representing a space axis or a time axis is generated, additional information (106) associated with the axis information is generated, the additional information including presence information indicating that the region of interest is present and content information indicating content of the region of interest, and the low-dimensional images, the axis information, and the additional information are displayed on a display.

The present disclosure relates to a non-transitory computer-readable medium storing computer-executable instructions that, when executed, cause a processor to perform operations, including generating an imaging data set having both scan data and digitized biopsy data from a patient with small cell lung cancer (SCLC). Scan derived features are extracted from the scan data and biopsy derived features are extracted from the digitized biopsy data. A radiomic-pathomic risk score (RPRS) is calculated from one or more of the scan derived features and one or more of the biopsy derived features. The RPRS is indicative of a prognosis of the patient.

An information processing method includes deducing a diagnosis name derived from a medical image on the basis of an image feature amount corresponding to a value indicating a feature of a medical image, deducing an image finding representing a feature of the medical image on the basis of the image feature amount, and presenting the image finding deduced in the deducing the image finding which is affected by an image feature amount common to the image feature amount that has affected the deduction of the diagnosis name in the deducing the diagnosis name and the diagnosis name to a user.

An information processing apparatus includes at least one processor, and the processor derives a property for at least one predetermined property item which is related to a structure of interest included in an image. The processor specifies a basis region serving as a basis for deriving the property related to the structure of interest for each property item and derives a basis image including the basis region.