A time-of-flight mass spectrometry device, includes: a flight tube: a flight tube power supply that applies a voltage to the flight tube; and a noise reduction circuit that is connected to a flight tube voltage portion which lies between the flight tube and the flight tube power supply, wherein: the noise reduction circuit inverts and amplifies an input voltage from an input end of the noise reduction circuit, and feeds inverted and amplified voltage back to the flight tube voltage portion through an output end.

A time-of-flight mass spectrometry device, includes: a flight tube: a flight tube power supply that applies a voltage to the flight tube; and a noise reduction circuit that is connected to a flight tube voltage portion which lies between the flight tube and the flight tube power supply, wherein: the noise reduction circuit inverts and amplifies an input voltage from an input end of the noise reduction circuit, and feeds inverted and amplified voltage back to the flight tube voltage portion through an output end.