A tube preparation step of preparing a resin tube that has a tube wall impregnable with a solution including a fine substance and is made of a light-transmitting resin material, a solution preparation step of preparing a solution that includes a fine fluorescent substance that emits fluorescence or a fine scattering substance that scatters light as an oscillation material and an impregnation step of causing the resin tube to be immersed in the solution and causing the tube wall of the resin tube to be impregnated with the oscillation material, are included.

An optical arrangement for adjusting the wavelength of light, comprising: a first light source arranged to generate a first beam of light at a first wavelength; a second light source arranged to generate seed light at a second wavelength; a first Raman shifting medium arranged to receive the light from the first light source in combination with the seed light from the second light source, and to produce, by stimulated Raman scattering, output light at the second wavelength and having temporal properties determined by those of the first beam of light; a third light source arranged to generate seed light at a third wavelength; and a second Raman shifting medium arranged to receive the output light from the first Raman shifting medium in combination with the seed light from the third light source, and to produce, by stimulated Raman scattering, output light at the third wavelength and having temporal properties determined by those of the output light from the first Raman shifting medium; wherein the third wavelength is greater than the second wavelength, and the second wavelength is greater than the first wavelength; wherein the frequency difference between the first beam of light and the seed light from the second light source is a frequency difference where the first Raman shifting medium exhibits Raman gain; and wherein the frequency difference between the output light from the first Raman shifting medium and the seed light from the third light source is a frequency difference where the second Raman shifting medium exhibits Raman gain. Also provided is a corresponding method of adjusting the wavelength of light.

A tube preparation step of preparing a resin tube that has a tube wall impregnable with a solution including a fine substance and is made of a light-transmitting resin material, a solution preparation step of preparing a solution that includes a fine fluorescent substance that emits fluorescence or a fine scattering substance that scatters light as an oscillation material and an impregnation step of causing the resin tube to be immersed in the solution and causing the tube wall of the resin tube to be impregnated with the oscillation material, are included.

A tube preparation step of preparing a resin tube that has a tube wall impregnable with a solution including a fine substance and is made of a light-transmitting resin material, a solution preparation step of preparing a solution that includes a fine fluorescent substance that emits fluorescence or a fine scattering substance that scatters light as an oscillation material and an impregnation step of causing the resin tube to be immersed in the solution and causing the tube wall of the resin tube to be impregnated with the oscillation material, are included.

The present invention relates to a method and system for identifying mechanical properties of a cell nucleus through a label-free cell analysis based on Brillouin light scattering techniques. The present application additionally provides a method and system for identifying cancerous cells based on mechanical properties of the cell nucleus.

A fluid filled fiber for a quasi-phase matched generator and a laser incorporating such a fluid filled fiber. The liquid filled fiber has charge transfer molecules dissolved in a solvent. In another embodiment, the liquid of the LF fiber comprises or consists essentially of highly polar liquids and/or charge transfer molecules having relatively high molecular dipole values. The liquid filled fiber is usable with a laser for differential frequency generation.

The present invention relates to a method and system for identifying mechanical properties of a cell nucleus through a label-free cell analysis based on Brillouin light scattering techniques. The present application additionally provides a method and system for identifying cancerous cells based on mechanical properties of the cell nucleus.

A fluid filled fiber for a quasi-phase matched generator and a laser incorporating such a fluid filled fiber. The liquid filled fiber has charge transfer molecules dissolved in a solvent. In another embodiment, the liquid of the LF fiber comprises or consists essentially of highly polar liquids and/or charge transfer molecules having relatively high molecular dipole values. The liquid filled fiber is usable with a laser for differential frequency generation.