The present relates to a device for providing a radiation treatment to a patient comprising:—an electron source for providing a beam of electrons, and—a linear accelerator for accelerating said beam until a predetermined energy, and—a beam delivery module for delivering the accelerated beam from said linear accelerator toward the patient to treat a target volume with a radiation dose, The device further comprises intensity modulation means configured to modulate the distribution of the radiation dose in the target volume according to a predetermined pattern. The pattern is determined to match the dimensions of a target volume of at least about 50 cm.sup.3, and/or a target volume located at least about 5 cm deep in the tissue of the patient with said radiation dose, The radiation dose distributed is up to about 20 Gy delivered during an overall treatment time less than about 50 ms.

The present relates to a device for providing a radiation treatment to a patient comprising:—an electron source for providing a beam of electrons, and—a linear accelerator for accelerating said beam until a predetermined energy, and—a beam delivery module for delivering the accelerated beam from said linear accelerator toward the patient to treat a target volume with a radiation dose, The device further comprises intensity modulation means configured to modulate the distribution of the radiation dose in the target volume according to a predetermined pattern. The pattern is determined to match the dimensions of a target volume of at least about 50 cm.sup.3, and/or a target volume located at least about 5 cm deep in the tissue of the patient with said radiation dose, The radiation dose distributed is up to about 20 Gy delivered during an overall treatment time less than about 50 ms.

Described are devices, systems, and methods for modulating the spectral energy distribution produced by an x-ray source via control of the energy of the x-ray-generating electron beam, e.g., for energy-modulated radiation therapy or other purposes. In some embodiments, such energy modulation is achieved by an add-on device to a linear accelerator. Also disclosed are computational methods and computer program products for planning energy-modulated therapy.

Described are devices, systems, and methods for modulating the spectral energy distribution produced by an x-ray source via control of the energy of the x-ray-generating electron beam, e.g., for energy-modulated radiation therapy or other purposes. In some embodiments, such energy modulation is achieved by an add-on device to a linear accelerator. Also disclosed are computational methods and computer program products for planning energy-modulated therapy.

Described are devices, systems, and methods for modulating the spectral energy distribution produced by an x-ray source via control of the energy of the x-ray-generating electron beam, e.g., for energy-modulated radiation therapy or other purposes. In some embodiments, such energy modulation is achieved by an add-on device to a linear accelerator. Also disclosed are computational methods and computer program products for planning energy-modulated therapy.

Described are devices, systems, and methods for modulating the spectral energy distribution produced by an x-ray source via control of the energy of the x-ray-generating electron beam, e.g., for energy-modulated radiation therapy or other purposes. In some embodiments, such energy modulation is achieved by an add-on device to a linear accelerator. Also disclosed are computational methods and computer program products for planning energy-modulated therapy.

A particle accelerator comprising a waveguide comprising a series of acceleration cells. The series of acceleration cells comprise an input acceleration cell configured to accelerate a beam of electrons along the central axis of the cells. A source of electrons is configured to input a beam of electrons into the input acceleration cell and a magnet arrangement is configured to prevent electrons that have deviated from the beam of electrons from hitting the source of electrons.

A particle accelerator comprising a waveguide comprising a series of acceleration cells. The series of acceleration cells comprise an input acceleration cell configured to accelerate a beam of electrons along the central axis of the cells. A source of electrons is configured to input a beam of electrons into the input acceleration cell and a magnet arrangement is configured to prevent electrons that have deviated from the beam of electrons from hitting the source of electrons.

A high gradient linear accelerating structure can propagate high frequency waves at a negative harmonic to accelerate low-energy ions. The linear accelerating structure can provide a gradient of 50 MV/m for particles at a β of between 0.3 and 0.4. The high gradient structure can be a part of a linear accelerator configured to provide an energy range from an ion source to 450 MeV/u for .sup.12C.sup.6+ and 250 MeV for protons. The linear accelerator can include one or more of the following sections: a radiofrequency quadrupole (RFQ) accelerator operating at the sub-harmonic of the S-band frequency, a high gradient structure for the energy range from ˜45 MeV/u to ˜450 MeV/u.

A high gradient linear accelerating structure can propagate high frequency waves at a negative harmonic to accelerate low-energy ions. The linear accelerating structure can provide a gradient of 50 MV/m for particles at a β of between 0.3 and 0.4. The high gradient structure can be a part of a linear accelerator configured to provide an energy range from an ion source to 450 MeV/u for .sup.12C.sup.6+ and 250 MeV for protons. The linear accelerator can include one or more of the following sections: a radiofrequency quadrupole (RFQ) accelerator operating at the sub-harmonic of the S-band frequency, a high gradient structure for the energy range from ˜45 MeV/u to ˜450 MeV/u.