A secure specimen sample bottle includes a base container for receiving a specimen. The base container has a plurality of locking protrusions formed along an inner surface of the base receptacle. A bottle includes a lock ring that has an upright spire structure that has a closed top end and the opposing open bottom end including a plurality of flexible fins that are configured to interlockingly mate with the locking protrusions so as to prevent removal of the lock ring relative to the base container upon engagement of the flexible fins to the locking protrusions. A removable cap is coupled to the lock ring.

A tamper-evident closure (1) for a container, the closure comprising: a shell comprising a first shell part (3A) and a second shell part (3B); and a tamper-evident overcap, the overcap comprising a cap (4A) which is fixed to the exterior of the first shell part and a tamper-evident member (4B) which is releasably connected to the cap (4A) and releasably located around the exterior of at least part of the second shell part (3B), such that the first and second shell parts (3A, 3B) cannot be separated unless the member (4B) is released, and thereafter the cap (4A) is removable together with the first shell part (3A).

A system for opening a secure specimen sample bottle includes a base having a first area and a first raised hollow portion for receiving and holding the specimen sample bottle. The first raised hollow portion has a groove formed along an outer surface thereof. The system includes a cutter for cutting a first portion of the specimen sample bottle. The cutter has a handle at a first end and a second end portion that receives the first portion of the specimen sample bottle and a blade for cutting the first portion. The second end portion has a flange with a raised rail formed along an inner surface of the flange, with the raised rail being received within the groove to couple the cutter to first raised portion during performance of a cutting operation.

A secure specimen sample bottle includes a base container for receiving a specimen. The base container has a plurality of locking protrusions formed along an inner surface of the base receptacle. A bottle includes a lock ring that has an upright spire structure that has a closed top end and the opposing open bottom end including a plurality of flexible fins that are configured to interlockingly mate with the locking protrusions so as to prevent removal of the lock ring relative to the base container upon engagement of the flexible fins to the locking protrusions. A removable cap is coupled to the lock ring.

A system for opening a secure specimen sample bottle includes a base having a first area and a first raised hollow portion for receiving and holding the specimen sample bottle. The first raised hollow portion has a groove formed along an outer surface thereof. The system includes a cutter for cutting a first portion of the specimen sample bottle. The cutter has a handle at a first end and a second end portion that receives the first portion of the specimen sample bottle and a blade for cutting the first portion. The second end portion has a flange with a raised rail formed along an inner surface of the flange, with the raised rail being received within the groove to couple the cutter to first raised portion during performance of a cutting operation.

A tamper-evident closure (1) for a container, the closure comprising: a shell comprising a first shell part (3A) and a second shell part (3B); and a tamper-evident overcap, the overcap comprising a cap (4A) which is fixed to the exterior of the first shell part and a tamper-evident member (4B) which is releasably connected to the cap (4A) and releasably located around the exterior of at least part of the second shell part (3B), such that the first and second shell parts (3A, 3B) cannot be separated unless the member (4B) is released, and thereafter the cap (4A) is removable together with the first shell part (3A).