An organ implant, such as a heart implant, including a support structure having a plurality of pores and defining passages configured for the growth of blood vessels; and stem cells from at least one soft tissue source of a patient deposited into the pores of the support structure is described. The implant is configured to repair a portion of an organ of the patient.

A method of creating a synthetic bone implant configured for implantation into a patient is provided. The method includes constructing a synthetic three dimensional composite support structure integrally formed as one piece, the synthetic three dimensional composite support structure including a nonbiodegradable material and having a porous construction with a plurality of passages, wherein the support structure is constructed to have a configuration corresponding to at least one of a bone and a portion of a bone to be replaced in the patient. The method also includes providing the synthetic three dimensional composite support structure to enable placement of the synthetic three dimensional composite support structure in the patient, wherein an outer surface of the support structure is configured to be pressed adjacent the bone, wherein the synthetic three dimensional composite support structure is configured to be positioned in the body to promote growth of tissue in the body of the patient into at least a portion of the synthetic three dimensional composite support structure by having at least a portion of the porous construct adjacent the bone enabling biologic structures to grow into the plurality of passages in the porous construction to securely connect the support structure in place in the body of the patient.

A method of creating a synthetic bone implant configured for implantation into a patient is provided. The method includes constructing a synthetic three dimensional composite support structure integrally formed as one piece, the synthetic three dimensional composite support structure including a nonbiodegradable material and having a porous construction with a plurality of passages, wherein the support structure is constructed to have a configuration corresponding to at least one of a bone and a portion of a bone to be replaced in the patient. The method also includes providing the synthetic three dimensional composite support structure to enable placement of the synthetic three dimensional composite support structure in the patient, wherein an outer surface of the support structure is configured to be pressed adjacent the bone, wherein the synthetic three dimensional composite support structure is configured to be positioned in the body to promote growth of tissue in the body of the patient into at least a portion of the synthetic three dimensional composite support structure by having at least a portion of the porous construct adjacent the bone enabling biologic structures to grow into the plurality of passages in the porous construction to securely connect the support structure in place in the body of the patient.

An improved method of implanting cells in the body of a patient includes positioning viable cells on a support structure. One or more blood vessels may be connected with the support structure to provide a flow of blood through the support structure. A support structure may be positioned at any desired location in a patient's body. The support structure may be configured to replace an entire organ or a portion of an organ. An organ or portion of an organ may be removed from a body cells and/or other tissue is removed to leave a collagen matrix support structure having a configuration corresponding to the configuration of the organ or portion of an organ. Alternatively, a synthetic support structure may be formed. The synthetic support structure may have a configuration corresponding to a configuration of an entire organ or only a portion of an organ.

A method of and system for recirculating a fluid in a particle production system. A reactor produces a reactive particle-gas mixture. A quench chamber mixes a conditioning fluid with the reactive particle-gas mixture, producing a cooled particle-gas mixture that comprises a plurality of precursor material particles and an output fluid. A filter element filters the output fluid, producing a filtered output. A temperature control module controls the temperature of the filtered output, producing a temperature-controlled, filtered output. A content ratio control module modulates the content of the temperature-controlled, filtered output, thereby producing a content-controlled, temperature-controlled, filtered output. A channeling element supplies the content-controlled, temperature-controlled, filtered output to the quench chamber, wherein the content-controlled, filtered output is provided to the quench chamber as the conditioning fluid to be used in cooling the reactive particle-gas mixture.

An apparatus for cooling a reactive mixture, comprising: a reactor configured to form the reactive mixture; a quench chamber comprising a frusto-conical body having a wide end, a narrow end, and a quench region formed between the wide and narrow end, wherein the quench chamber is configured to receive the reactive mixture from the plasma reactor through a reactive mixture inlet into the quench region, to receive a conditioning fluid through at least one fluid inlet, and to flow the conditioning fluid into the quench region, wherein the frusto-conical body is configured to produce a turbulent flow within the quench region with the flow of the conditioning fluid into the quench region, thereby promoting the quenching of the reactive mixture to form a cooled gas-particle mixture; and a suction generator configured to force the cooled gas-particle mixture out of the quench chamber.