An automatic slicing and collecting device, the device including: a first tank, a vibrating microtome, a first pipeline, and a second pipeline. The first tank is filled with a buffer solution. The vibrating microtome is disposed in the first tank. One end of the first pipeline is connected to the vibrating microtome to collect sections, and the other end of the first pipeline is connected to a pump. The pump includes a reversible motor. The first pipeline is provided with a first valve, and a filter is disposed between the pump and the first pipeline. One end of the second pipeline is disposed between the first valve of the first pipeline and the pump, and the second pipeline is provided with a second valve.

A thin-section preparation method and device includes, in a one-blade set state where an entire first cutting blade is held by a holder, performing a first rough cutting step of rough cutting an embedded block using a first end region of the first cutting blade, and a first main cutting step of main cutting the embedded block using a second end region of the first cutting blade; and further includes, in a two-blade set state where the second end region of the first cutting blade and a first end region of a second cutting blade are held by the holder, performing a second rough cutting step of rough cutting the embedded block using the second end region of the first cutting blade, and a second main cutting step of main cutting the embedded block using the first end region of the second cutting blade.

An apparatus and method for faster pathology are provided that removes the need for time consuming preparation of a hardened tissue block. Such hardening is necessary to enable cutting of the thin tissue sections required for pathology evaluation. Rather the tissue specimen is hardened by freezing only at the surface from which tissue is to be sectioned by contact with a cold surface or slide thereby lessening the time required for hardening. Sectioning is performed by passing a cutting device such as a blade, cutting wire or laser beam along a plane parallel to the cold surface and using the cold surface as a guide.

An apparatus having a sample sectioning device including a cutting mechanism that is operable to cut sections from a sample and a sample holder that is operable to hold the sample. The apparatus further includes a drive system coupled with the sample holder to drive movement of the sample holder and a reciprocating member coupled to the drive system to drive vertical movement of the drive system. The reciprocating member to move in a reciprocating manner within an angle of rotation of less than 180 degrees. A surface orientation sensor may further be provided that is operable to sense an orientation of a surface of the sample held by the sample holder.

An apparatus and method for faster pathology are provided that removes the need for time consuming preparation of a hardened tissue block. Such hardening is necessary to enable cutting of the thin tissue sections required for pathology evaluation. Rather the tissue specimen is hardened by freezing only at the surface from which tissue is to be sectioned by contact with a cold surface or slide thereby lessening the time required for hardening. Sectioning is performed by passing a cutting member such as a blade, cutting wire or laser along a plane parallel to the cold surface and using the cold surface as a guide.

Devices and methods for processing animal or human tissue are provided. The devices may include a vacuum surface to secure the tissue in place and an apparatus for removing fat or other material from the tissue. The apparatus can include one or more blades and/or a fluid jet system.

Devices and methods for processing animal or human tissue are provided. The devices may include a vacuum surface to secure the tissue in place and an apparatus for removing fat or other material from the tissue. The apparatus can include one or more blades and/or a fluid jet system.

An automatic slicing and collecting device, the device including: a first tank, a vibrating microtome, a first pipeline, and a second pipeline. The first tank is filled with a buffer solution. The vibrating microtome is disposed in the first tank. One end of the first pipeline is connected to the vibrating microtome to collect sections, and the other end of the first pipeline is connected to a pump. The pump includes a reversible motor. The first pipeline is provided with a first valve, and a filter is disposed between the pump and the first pipeline. One end of the second pipeline is disposed between the first valve of the first pipeline and the pump, and the second pipeline is provided with a second valve.

A microtome method and apparatus includes a microtome blade configured to oscillate in a direction transverse to a direction of advancing a cut, and a first flexure to support and guide the blade. The first flexure is compliant in the transverse direction while being stiff in the cut direction. A second flexure operatively engaged at one end portion with the first flexure, is stiff in the transverse direction while being compliant in the cut direction. The other end portion of the second flexure is rotatably engaged by an eccentric driven by a rotatable actuator, which oscillates the blade in the transverse direction while effectively isolating non-transverse motion from the blade. The second flexure is configured to move independently of any guides or other stationary objects during oscillation.

An apparatus having a sample sectioning device including a cutting mechanism that is operable to cut sections from a sample and a sample holder that is operable to hold the sample. The apparatus further includes a drive system coupled with the sample holder to drive movement of the sample holder and a reciprocating member coupled to the drive system to drive vertical movement of the drive system. The reciprocating member to move in a reciprocating manner within an angle of rotation of less than 180 degrees. A surface orientation sensor may further be provided that is operable to sense an orientation of a surface of the sample held by the sample holder.