Fluid flow manifold assemblies for use in fluid flow sets are provided. The fluid flow manifold assembly includes a body having a main fluid channel and a reinforcing plate, the main fluid channel having a fluid inlet, a fluid outlet and a drug port. A flow control assembly is disposed opposite the main fluid channel from the drug port. The flow control assembly is configured to shut off fluid flow through the drug port into the main fluid channel with a plunger of the flow control assembly in a closed position and to allow incremental levels of fluid flow through the drug port into the main fluid channel by variably retracting the plunger based on rotation of a knob of the flow control assembly.

Fluid flow manifold assemblies for use in fluid flow sets are provided. The fluid flow manifold assembly includes a body having a main fluid channel, an inlet connector, an outlet connector and a drug port. A flow control assembly is disposed opposite the main fluid channel from the drug port. The flow control assembly includes a plunger, a seal member and a knob, wherein the plunger is disposed within the main fluid flow channel in a full open flow position and is configured to extend through the main fluid channel and be sealingly received by the drug port in a closed position, wherein the plunger position is based on rotation of the knob. Fluid flow sets with fluid flow manifold assemblies are also provided.

A valve is provided for controlling flow along a fluid line that includes an outer shell and an inner housing slidably disposed therein that includes connector threads surrounding a boss on one end and a passage through the boss. A backing member is coupled to the outer shell and has a sealing pin extending into the passage. The inner housing is movable helically relative to the outer shell from a closed position wherein a sealing pin engages an outlet opening at the distal end of the boss to seal the opening and an open position in which the inner housing is directed away from the sealing pin to open a fluid path through the valve. A torque limiter mechanism between the outer shell and inner housing resists movement from the valve closed position to the valve open position until a selected torque level is reached.

Methods of assembling a manifold for a medical waste collection system. A flapper valve unit is secured to a head of a cap. A filter element is positioned within a shell. Basket hands of the filter element are fitted between first pairs of ribs of the cap skirt. Fingers of the shell are fitted between second pairs of ribs of the cap skirt. The cap is secured to the shell to cover an open distal end of the shell. A drip stop is secured to the proximal end base of the shell to seat within the outlet opening. Ears may be fitted through holes defined by the flapper valve unit and cap holes defined by the cap so as to snap lock to the head of the cap. The hub of the flapper valve unit may be compressed with the ears snap locked to the head of the cap.

A dual-handle and dual-control faucet includes a faucet body and a faucet spout, a mechanical control unit, a sensor control unit, a water flow sensor and a controller that are mounted to the faucet body. The controller detects whether the mechanical control unit is operated through the water flow sensor. When the mechanical control unit acts, the sensor control unit becomes inactive. The faucet has a mechanical control mode and a sensor control mode and is convenient to use.

A duct intersection comprising a first duct portion and a second duct portion extending laterally from a side of the first duct portion. At least one flow modifier is mounted inside one of the first and second duct portions. The flow modifier is a contoured duct liner and/or the flow modifier includes at least one turning vane. The duct intersection may also include a transition portion extending between the first and second duct portions, wherein the transition portion has a length extending along a side of the first duct portion and a depth extending away from the side of the first duct portion, wherein the length is greater than a diameter of the second duct portion.

Methods of assembling a manifold for a medical waste collection system. A flapper valve unit is secured to a head of a cap. A filter element is positioned within a shell. Basket hands of the filter element are fitted between first pairs of ribs of the cap skirt. Fingers of the shell are fitted between second pairs of ribs of the cap skirt. The cap is secured to the shell to cover an open distal end of the shell. A drip stop is secured to the proximal end base of the shell to seat within the outlet opening. Ears may be fitted through holes defined by the flapper valve unit and cap holes defined by the cap so as to snap lock to the head of the cap. The hub of the flapper valve unit may be compressed with the ears snap locked to the head of the cap.

A system for processing a biological sample includes a substrate comprising a plurality of wells and a plurality of flow channels. The system further includes a flow control system comprising a manifold having a plurality of ports configured to fluidically couple to the plurality of wells, and one or more containment structures configured to contain carrier fluid and fluidically couple to the ports. The flow control system further includes a cradle configured to removably receive the substrate. The flow control system is configured to transmit pressure differential, via the manifold, to the plurality of wells so as to cause a plurality of sample volumes held by at least some wells of the plurality of wells to flow through respective flow channels and cause the carrier fluid to flow through the flow channels and form a plurality of droplets of the plurality of sample volumes separated by the carrier fluid.

A system for processing a biological sample can include a droplet generation assembly comprising a plurality of first reservoirs configured to contain an aqueous sample and a plurality of second reservoirs configured to contain a carrier fluid immiscible with the aqueous sample. The plurality of first reservoirs and the plurality of second reservoirs can be arranged to be in respective flow communication in pairs of reservoirs comprising a first reservoir of the plurality of first reservoirs and a second reservoir of the plurality of second reservoirs constituting a plurality of pairs of reservoirs. The droplet generation assembly can further include a flow control system configured to control a pressure in the plurality of pairs of reservoirs so as to generate a flow of a series of volumes of the aqueous sample separated by the carrier fluid. The system can further include a thermocycling system.

A dual-handle and dual-control faucet includes a faucet body and a faucet spout, a mechanical control unit, a sensor control unit, a water flow sensor and a controller that are mounted to the faucet body. The controller detects whether the mechanical control unit is operated through the water flow sensor. When the mechanical control unit acts, the sensor control unit becomes inactive. The faucet has a mechanical control mode and a sensor control mode and is convenient to use.