A fabrication system may generally comprise an x-y positioning assembly, a clamping head to receive an end effector, wherein the clamping head is coupled to the x-y positioning assembly, a z positioning assembly, a platform including a surface that is rigid and substantially planar, wherein the platform is coupled to the z positioning assembly, and a controller operably coupled to the x-y positioning assembly, end effector, z positioning assembly, and platform. Methods of using the fabrication system are also described.