APPLICATOR FOR A TWO-COMPONENT FABRIC ADHESIVE

Abstract

The present invention relates to a dispensing system (1) having at least two chambers (2,3) for a tissue adhesive system comprising at least two components, wherein first chamber (2) is designed as a hollow cylinder (H), which has a closed design on an end face (2a) and an open design on its opposite end face (2b) and second chamber (3) in a solid cylinder (V) is designed as an annular gap (4) and annular gap (4) extends from an end face (3a) facing hollow cylinder (H) to a mixing chamber (5) arranged on opposite end (3b) of solid cylinder (V) and hollow cylinder (H) is arranged on the side of its open end face (2b) in annular gap (4) of solid cylinder (V) so it can move in longitudinal direction (L), wherein at least one feed duct (6) is designed in solid cylinder (V), which extends on the inside of annular gap (4) from end face (3a) of solid cylinder (V) facing hollow cylinder (H) to mixing chamber (5), wherein a mixing tube (7) is provisioned in mixing chamber (5), which projects laterally from solid cylinder (V) and is arranged so it can move essentially transversely to the longitudinal expansion of solid cylinder (V) and closes the inside of mixing tube (7) off from feed duct (6) and annular gap (4) in a first position and unblocks it in a second position. The invention also relates to a kit consisting of a dispensing system, which is filled with tissue adhesive system comprising at least two components as well as a method for closing a wound using said kit.

Claims

1.-22. (canceled)

23. A dispensing system having at least two chambers for a tissue adhesive system comprising at least components, wherein first chamber is designed as a hollow cylinder, which has a closed design onan end face and an open design on its opposite end face and second chamber in a solid cylinder is designed as an annular gap and annular gap extends from an end face facing hollow cylinder to a mixing chamber arranged on opposite end of solid cylinder and hollow cylinder is arranged on the side of its open end face in annular gap of solid cylinder so it can move in longitudinal direction, wherein at least one feed duct is designed in solid cylinder, which extends on the inside of annular gap from end face of solid cylinder facing hollow cylinder to mixing chamber, wherein a mixing tube is provisioned in mixing chamber, which projects laterally from solid cylinder and is arranged so it can move essentially transversely to the longitudinal expansion of solid cylinder and closes the inside of mixing tube off from feed duct and annular gap in a first position and unblocks it in a second position.

24. Dispensing system according to claim 23, wherein hollow cylinder and solid cylinder are manufactured from a rigid material, particularly from a plastic material, the polymer matrix of which is preferably selected from polyolefins, preferably polyethylene and polypropylene, ABS plastic, polycarbonate, polyester, preferably polyethylene terephthalate, poly(methyl)methacrylate, polyvinyl chloride, (2-component) epoxy resins, polystyrene, as well as mixtures and mixed polymerisates thereof.

25. Dispensing system according to claim 23, wherein an end stop device is designed in the area of the impact edge of open end face of hollow cylinder, which interacts with a corresponding end stop device designed on end face of solid cylinder facing hollow cylinder in such a way that hollow cylinder and solid cylinder can only be pulled apart to the point end stop devices touch each other.

26. Dispensing system according to claim 25, wherein end stop device on hollow cylinder is designed as a circumferential annular bead, which interacts with a mating surface surrounding the inside on solid cylinder as a corresponding end stop device.

27. Dispensing system according to claim 26, wherein a circumferential sealing element is provisioned on the annular bead, which interacts with at least one longitudinal surfaces of annular gap providing a seal.

28. Dispensing system according to claim 23, wherein longitudinal expansion of hollow cylinder is selected such that the height of the inner wall is substantially identical to the depth of annular gap.

29. Dispensing system according to claim 23, wherein the dispensing system has two chambers and the volume ratio of chambers is from 1:10 to 10:1.

30. Dispensing system according to claim 23, wherein the volume ratio of first chamber to second chamber is from 5:1 to 3:1.

31. Dispensing system according to claim 23, wherein hollow cylinder and solid cylinder are equipped with a securing device, which secures hollow cylinder and solid cylinder from being unintentionally pushed against each other.

32. Dispensing system according to claim 23, wherein hollow cylinder and solid cylinder have a circular, oval, polygonal/angular, ellipsoid or trapezoid cross-sectional surface, particularly a rectangular cross-sectional surface with rounded edges, wherein the ratio of the long side to the short side is at least 3:1.

33. Dispensing system according to claim 23, wherein the outside of hollow cylinder and/or solid cylinder is equipped with a profiling running in the longitudinal direction.

34. Dispensing system according to claim 23, wherein mixing elements are arranged within mixing tube, wherein mixing tube is designed in particular as a static mixer.

35. Dispensing system according to claim 23, wherein a latching mechanism is provisioned on mixing tube, which secures mixing tube in the first position so it cannot be unintentionally pulled out.

36. Dispensing system according to claim 23, wherein a retraction locking device is provisioned on mixing tube, which is designed in such a way that it secures mixing tube after being moved to the second position and prevents it from moving back.

37. Dispensing system according to claim 23, wherein mixing tube is guided in mixing chamber so that it cannot twist and equipped with one or more openings on its inward facing end on the side facing the feed duct, through which feed duct and/or annular gap can be connected to the inside of mixing tube if mixing tube is put in the second position.

38. Dispensing system according to claim 23, wherein mixing tube is equipped with a removable plug on its side out of solid cylinder.

39. Dispensing system according to claim 23, wherein mixing chamber is designed within solid cylinder.

40. Dispensing system according to claim 23, wherein an annular gap seal is provisioned in mixing chamber between the junction of the annular gap and the exterior opening of the mixing chamber, which serves to seal between mixing chamber and the outer surface of mixing tube in position 1 and position 2.

41. Dispensing system according to claim 23, wherein feed duct runs essentially parallel to annular gap and is spaced from the annular gap at least 2 mm.

42. Dispensing system according to claim 23, wherein hollow cylinder and solid cylinder are collectively enclosed in a foil bag.

43. A kit consisting of a dispensing system according to claim 23, and a tissue adhesive system comprising two components, optionally a process manual for wound closure using said kit, wherein the tissue adhesive system comprises at least one aspartic acid ester as a hardener with optionally at least one filler as a first component, and an isocyanate-functional prepolymer as a second component, wherein the first component is located in first chamber and the second component is located in second chamber of the dispensing system.

44. A method for closing a wound using a kit in accordance with claim 43 comprising the steps: a) pulling out mixing tube until the second position is reached; b) exerting pressure on hollow cylinder and solid cylinder relatively to each other in the longitudinal direction of cylinders, whereby both components of the tissue adhesive system are conveyed in the direction of mixing chamber and mixed together upon flowing through mixing tube; c) optionally discarding at least the first 10 mm of tissue adhesive discharging out of mixing tube; d) applying the tissue adhesive discharged through the continued application of pressure from mixing tube onto the wound; e) allowing the tissue adhesive to cure.

Description

[0064] FIG. 1 An embodiment of an apparatus pursuant to the invention in lateral plan view,

[0065] FIGS. 2a) and b) Detailed views of the first chamber of the apparatus from FIG. 1 diagonally from above,

[0066] FIGS. 3a) and b) Detailed views of the second chamber of the apparatus from FIG. 1 diagonally from above,

[0067] FIG. 4 A sectional view of the apparatus from FIG. 1 diagonally from above,

[0068] FIGS. 5a) and b) Detailed views of the mixing tube of the apparatus from FIG. 1 in lateral plan view and lateral sectional view, as well as

[0069] FIGS. 6a) and b) An embodiment of a kit pursuant to the invention prior to and after opening.

[0070] A dispensing system 1 pursuant to the invention is depicted in FIG. 1 in lateral plan view. Dispensing system 1 consists of two elongated, oval chambers 2, 3 for a tissue adhesive system comprising two components, for example, a system based on isocyanate-functional prepolymers on the basis of aliphatic polyisocyanates and amino-functional aspartic acid esters as one component and a polyol as a second component. Hollow cylinder H and solid cylinder V are manufactured from a rigid material, in the present case from polypropylene.

[0071] First chamber 2 is designed as a hollow cylinder H, which has a closed design on an end face 2a and an open design on its opposite end face 2b, thus forming a cavity for receiving a component of the tissue adhesive system. First chamber 2 is once again separately depicted in FIG. 2a) and b).

[0072] Second chamber 3 is designed as an oval annular gap 4 in a solid cylinder V. The second component of the tissue adhesive system can be filled in annular gap 4. Annular gap 4 extends from an end face 3a facing hollow cylinder H to a mixing chamber 5 designed therein on an opposite end 3b of solid cylinder V, wherein hollow cylinder H is arranged on the side of its open end face 2b in annular gap 4 of solid cylinder V so it can move in longitudinal direction L.

[0073] A mixing tube 7 is provisioned in mixing chamber 5, which is designed as a static mixer. Mixing tube 7 projects laterally from the solid cylinder V and is arranged essentially transversely to the longitudinal expansion of solid cylinder V.

[0074] The volumes of both chambers 2, 3 can be respectively adapted to the mixing ratio of the adhesive system, wherein the ratio of first chamber 2 to second chamber 3 at hand is approximately 3:1.

[0075] As seen in FIGS. 3a) and b), second chamber 3 consists of two elements 10a, 10b, which can be connected to each other firmly and gas-tight by means of a latching mechanism after being assembled in direction indicated by the dashed arrows. For the purpose of sealing between two elements 10a, 10b, one of these is equipped with a circumferential seal.

[0076] The division of second chamber 3 in two elements 10a, 10b serves the purpose of simplifying filling chambers 2, 3 with the components of the tissue adhesive system. Thus, initially first chamber 2 can be filled with the one component of the tissue adhesive system and assembled together with element 10a bearing annular gap 4 in such a way that the circumferential edge bead of first chamber 2 is inserted into annular gap 4. Oval, annular second element 10b is then slipped over first chamber 2 and connected to element 10a via the latching mechanism described above, whereby first chamber 2 is simultaneously clamped such that it can no longer become detached. Annular gap 4 of second chamber 3 is then filled with the other component of the tissue adhesive system. This occurs expediently prior to inserting mixing tube 7 through the opening of second chamber 3 provisioned for mixing tube 7. Alternatively, the base area of chamber 3 below mixing chamber 5 can also be designed to be removed, which simplifies filling into annular gap 4.

[0077] When filled and assembled, the bottom of the circumferential annular bead of first chamber 2 serves as a cylindrical surface and the top of the annular bead in conjunction with the circumferential bottom edge act as corresponding end stop devices 8, 9 of hollow cylinder H and solid cylinder V, such that hollow cylinder H and solid cylinder V can only be pulled apart to the point end stop devices 8, 9 touch each other. This prevents dispensing system 1 from being unintentionally opened. To ensure that the adhesive components are used as completely as possible when compressing the dispensing system, the longitudinal expansion of hollow cylinder H is selected such that the height of the inner wall is substantially identical to the depth of annular gap 4. This is particularly apparent from the sectional view in FIG. 4.

[0078] At least one feed duct 6 is designed in solid cylinder V, which extends on the inside of annular gap 4 from end face 3a of solid cylinder V facing hollow cylinder H to mixing chamber 5. The tissue adhesive component contained in hollow cylinder H is conveyed through feed duct 6 in the direction of mixing chamber 5 as soon as chambers 2, 3 are pushed into each other by compressing dispensing system 1. To ensure that no adhesive components can exit here on the interfaces between first and second chamber 2, 3, a circumferential sealing element 10 is provisioned externally on the annular bead, which interacts with both longitudinal surfaces of annular gap 4 providing a seal.

[0079] To prevent both adhesive components from prematurely and unintentionally mixing, mixing tube 7 closes the inside of mixing tube 7 off from feed duct 6 and annular gap 4 in a first position and only unblocks these openings in a second position, wherein the second position is defined by completely extracted mixing tube 7. This can be seen in particular in the detailed diagrams of mixing tube 7 in FIGS. 5a) and b). For this purpose, mixing tube 7 has two openings 14, 15 on its inward facing end on the side facing the feed duct 6, through which feed duct 6 and annular gap 4 can be connected to the inside of mixing tube 7 if mixing tube 7 is placed in the second position. To ensure that openings 14,15 remain in the proper position when extracting mixing tube 7, mixing tube 7 is guided in mixing chamber 5 so that it cannot twist.

[0080] FIGS. 5a) and b) further show that mixing tube 7 has a retraction locking device 13, which is designed such that it secures mixing tube 7 and prevents retraction after being moved into the second position, wherein retraction locking device 13 in the present case is designed as a latching element in the form of a barb, which stops therein after retracting mixing tube 7. A latching mechanism 12 in the form of an annular groove is embedded in the area of the front end of mixing tube 7, which secures mixing tube 7 from unintentionally slipping out when compressed with a corresponding pin on the outlet of mixing chamber 5.

[0081] Three annular gap seals 17, 18, 19 are provisioned in the mixing chamber 5 between the junction of annular gap 4 and the exterior opening of mixing chamber 5. Outer annular gap seal 17 serves as a seal between mixing chamber 5 and the outer surface of mixing tube 7 in position 1 and position 2. Middle annular gap seal 18 is arranged between the passage of annular gap 4 and feed duct 6 to prevent the two adhesive components from unintentionally mixing outside of mixing tube 7 in mixing chamber 5. Inside annular gap seal 19 is arranged on the side of feed duct 6 facing away from the passage of annular gap 4. Annular gap seal 19 can inhibit the component contained in hollow cylinder 2 from leaking into mixing chamber 5.

[0082] A kit 20 pursuant to the invention consisting of a dispensing system 1, as shown in FIGS. 1 to 5, is depicted in FIGS. 6a) and b). The respective exterior sides of hollow cylinder H and solid cylinder V are equipped with profiling 11 in the form of a ribbed profile running in the longitudinal direction, which enhances grip and stability. Two components of a polyurethane urea tissue adhesive system are filled in chambers 2, 3. The isocyanate functional prepolymer on the basis of aliphatic polyisocyanates and amino-functional aspartic acid esters is filled in annular gap 4 of the second chamber 3 and the polyol in the first chamber 2. For this purpose, as a 2-component tissue adhesive system, those presented in EP 2 173 782 B1, EP 2 182 018 B1, WO 2011/006606 A1, WO 2010/006714 A2, A3, EP 2 699 615 B1, WO 2013/104563 A1, WO 2012/107375 A1, WO 2013/092506 A1, EP 2 699 614 B1 or WO 2013/092504 A1 are used.

[0083] To ensure that no oxygen, no moisture or other environmental impacts can unfavorably alter the adhesive components, dispensing system 1 is shrink-wrapped in a foil bag 21 consisting of aluminized PET film and the outer end of mixing tube 7 is equipped with a removable plug 16. Removable plug 16 also serves to extract mixing tube 7 from mixing chamber 5 during use. For simplified handling, foil bag 21 is provided with a tear line in the area of projecting mixing tube 7, which enables a systematic opening of foil bag 21 on mixing tube 7. Thus, removing entire foil bag 21 is not required when using the system; rather it is sufficient to open it in the area of plug 16.

[0084] To fill kit 20 pursuant to the invention with a 2-component tissue adhesive system, it is possible to proceed in such a manner that first chamber 2 is filled with the one component of the tissue adhesive system in a dry inert gas atmosphere and assembled together with element 10a bearing annular gap 4 in such a way that the circumferential edge bead of first chamber 2 is inserted into annular gap 4. Oval, annular second element 10b is then stripped over first chamber 2 and connected to element 10a via the latching mechanism described above, whereby first chamber 2 is simultaneously clamped such that it can no longer become detached. Annular gap 4 of second chamber 3 is then filled with the other component of the tissue adhesive system. This occurs expediently prior to inserting mixing tube 7 through the opening of second chamber 3 provisioned for mixing tube 7. Alternatively, the base area of chamber 3 below mixing chamber 5 can also be designed to be removed, which simplifies filling into annular gap 4. Mixing tube 7 is then inserted into filled dispensing system 1 over latching mechanism 12 and shrink-wrapped under dry inert gas in a foil bag 21, the inside of which is aluminized. u

[0085] To use kit 20 pursuant to the invention for closing a wound, for example a laceration on the arm, by pulling on plug 16, foil bag 21 is simultaneously tom open, mixing tube 7 is pulled out until the end position is reached, and plug 16 is then removed by a slightly tilting pulling movement. This can also be done, for example, through the use of teeth if the arm injury does not enable the use of both hands. The dispensing system is then compressed with one hand so that first and second chamber 2, 3 are pushed together, whereby both components are conveyed into mixing tube 7, mixed there, and discharged at the opening of mixing tube 7. The first 2 cm of discharged compound can be discarded. The subsequent adhesive mixture strand is then applied directly to the bleeding wound, where the wound adhesive, accelerated through the moisture contact with the wound, hardens within 30 seconds to 3 minutes depending on the adhesive system, and thus stops the bleeding.

LIST OF REFERENCE NUMBERS

[0086] 1 Dispensing system [0087] 2 Chamber [0088] 2a End face [0089] 2b End face [0090] 3 Chamber [0091] 3a End face [0092] 3b End face [0093] 4 Annular gap [0094] 5 Mixing chamber [0095] 6 Feed duct [0096] 7 Mixing tube [0097] 8 End stop device [0098] 9 End stop device [0099] 10 Circumferential seal [0100] 10a Element [0101] 10b Element [0102] 11 Profiling [0103] 12 Latching mechanism [0104] 13 Retraction locking device [0105] 14 Opening [0106] 15 Opening [0107] 16 Plug [0108] 17 Outer annular gap seal [0109] 18 Middle annular gap seal [0110] 19 Inner annular gap seal [0111] 20 Kit [0112] 21 Foil bag [0113] H Hollow cylinder [0114] V Solid cylinder [0115] L Longitudinal direction