DEVICE FOR TREATMENT OF A TISSUE AND METHOD OF PREPARATION OF AN IMAGE OF AN IMAGE-GUIDED DEVICE FOR TREATMENT OF A TISSUE

Abstract

A device for treatment of a tissue (8) of a living being, including a transducer (4) for emitting a beam of ultrasound waves mounted on a movable treatment head (1), an ultrasonic imaging device (2, 3), optionally an inflatable balloon (5) surrounding the treatment head (1) and containing a coupling fluid, and a control unit for controlling movement of the treatment head (1) and operation of the transducer (4) and the imaging device (2, 3). In order to avoid displacement of tissues (7, 8) during displacement of the treatment head (1) and increase imaging quality, the treatment head (1) is adjustable to at least two of a treatment position (T), a monitoring position (M) and a travel position (S).

Claims

1-17. (canceled)

18. A device for treatment of a tissue of a living being, the device comprising: a transducer, for emitting a beam of ultrasound waves for irradiating the tissue, mounted on a movable treatment head, and the beam being focused on or focusable onto a focal point; an ultrasonic imaging device mounted on the treatment head having an imaging plane intersecting the focal point; an inflatable balloon at least partially surrounding the treatment head, containing a coupling fluid and defining a contact surface of the treatment head; and a control unit for controlling movement of the treatment head and operation of the transducer and the imaging device; wherein the treatment head is adjustable to a treatment position and a monitoring position, in the monitoring position, a distance between the transducer and the tissue is smaller than in the treatment position, and the control unit is adapted to: trigger the transducer to emit at least one beam of ultrasound waves when the treatment head is in the treatment position, and perform imaging of an area, surrounding the tissue, at least when the treatment head is in the monitoring position.

19. The device according to claim 18, wherein the control unit is adapted to move the treatment head, after emission of an ultrasound pulse from the transducer, from the treatment position to the monitoring position.

20. The device according to claim 18, wherein, after the treatment head is brought from the treatment position to the monitoring position, the control unit is adapted to move the treatment head to the treatment position for further emission of an ultrasound pulse from the transducer.

21. The device according to claim 18, wherein the control unit is adapted to control at least one of a position and an adjustment of the treatment head using the ultrasonic imaging device.

22. The device according to claim 18, wherein the control unit is adapted to control a pressure in the balloon.

23. A method for operating a device for treatment of a tissue of a living being, the device including: a transducer for emitting a beam of ultrasound waves for irradiating the tissue mounted on a movable treatment head, and the beam being focused on or focusable onto a focal point; an ultrasonic imaging device mounted on the treatment head having an imaging plane intersecting the focal point; an inflatable balloon, at least partially surrounding the treatment head, containing a coupling fluid and defining a contact surface of the treatment head; a control unit for controlling movement of the treatment head and operation of the transducer and the imaging device; wherein the treatment head is adjustable, along an axis, to at least two of a treatment position, a monitoring position and a travel position, in the monitoring position, a distance between the transducer and the tissue is smaller than in the treatment position, in the travel position, a distance between the contact surface and the tissue or between the transducer and the tissue is larger than in the treatment position, or a compression force on the tissue is reduced, and the control unit: triggers the transducer to emit at least one beam of ultrasound waves when the treatment head is in the treatment position, positions the treatment head in a plane substantially perpendicular to the axis when the treatment head is in the travel position, and performs imaging of an area surrounding the tissue at least when the treatment head is in the monitoring position.

24. A method of preparation of an image of an image-guided therapeutic device including a treatment head with a transducer for emitting a beam of ultrasound waves for irradiating a tissue, the beam being focused on or focusable onto a focal point, and an ultrasonic imaging device having an imaging plane, the method comprising the following steps: providing an image of a treatment region; displaying the image on a display; choosing a width sector of the treatment region to be analyzed; and drawing a line representing an artefact (9) and visualizing the line on the display together with the image of the treatment region.

25. The method according to claim 24, wherein an offset value is a characteristic of the imaging device.

26. The method according to claim 24, wherein the width sector of the treatment region to be analyzed is determined automatically by an image analysis program.

27. The method according to claim 25, wherein the width sector of the treatment region to be analyzed is determined automatically by an image analysis program.

28. The method according to claim 24, wherein the step of drawing a line representing an artefact (9) is performed automatically by determining the skin surface line via an image analysis program.

29. The method according to claim 25, wherein the step of drawing a line representing an artefact (9) is performed automatically by determining the skin surface line via an image analysis program.

30. The method according to claim 26, wherein the step of drawing a line representing an artefact (9) is performed automatically by determining the skin surface line via an image analysis program.

31. A device including a calculating unit adapted to perform the following steps: providing an image of a treatment region; displaying the image on a display; choosing a width sector of the treatment region to be analyzed; determining a skin surface line in the chosen width sector; and drawing a line (9) representing an artefact and visualizing the line on the display together with the image of the treatment region.

32. The device according to claim 18, wherein the treatment head is further adjustable to a travel position.

33. The device according to claim 32, wherein, before an ultrasound pulse is emitted from the transducer, the control unit is adapted to move the treatment head from the travel position to the treatment position.

34. The device according to claim 32, wherein the control unit is adapted to move the treatment head from the travel position to the monitoring position to monitor the tissue by the imaging device and then to the treatment position before an ultrasound pulse is emitted from the transducer.

35. The device according to claim 32, wherein the control unit is adapted to move the treatment head to the travel position for further positioning of the treatment head after a preceding movement.

36. The device according to claim 22, wherein the treatment head is further adjustable to a travel position.

37. The device according to claim 36, wherein the control unit is adapted to bring a pressure in the balloon to a first value, when the treatment head is in the travel position, and to a second value higher than the first value, when the treatment head is in the treatment position.

38. The device according to claim 32, wherein the control unit is adapted to bring a pressure in the balloon to a first value, when the treatment head is in the travel position, and to a second value higher than the first value, when the treatment head is in the treatment position.

39. The device according to claim 36, wherein the control unit is adapted to change a pressure in the balloon from a first value to a second value, lower than the first value, when the treatment head is in the travel position and is positioned in a plane substantially perpendicular to the axis.

40. The device according to claim 31, wherein the control unit is adapted to change a pressure in the balloon from a first value to a second value, lower than the first value, when the treatment head is in the travel position and is positioned in a plane substantially perpendicular to the axis.

Description

[0049] The invention will be described below by means of a preferred embodiment in connection with the figures. The figures show:

[0050] FIG. 1: a schematic sectional view of a device according to the present invention in, from left to right, a treatment position, monitoring position and travel position;

[0051] FIG. 2: a schematic view of a displacement pattern of the treatment head according to the method of the present invention;

[0052] FIG. 3: a view of a displayed image, where a skin ghost has been identified with a method according to the present invention.

[0053] FIG. 1 shows a treatment head 1 in a sectional view, whereby the section plane corresponds to an imaging plane of an echography device 2. An imaging array 3 of the echography device is arranged within an HIFU transducer 4 having a shape of a section of a sphere surface. The transducer 4 is of a fixed-focal-point type, the beam of ultrasound waves emitted by the transducer 4 being focused on a focal point F.

[0054] The transducer is enclosed by a flexible membrane 5 of a material with low ultrasound reflection and is filled with an ultrasound coupling fluid.

[0055] The membrane 5 is contacting a skin 6 of a patient delimiting a tissue 7 and thus defining a contact surface. A tumour 8, which must be treated, is located within the tissue 7.

[0056] The treatment head 1 is shown in the FIG. 1 in three different positions, namely from left to right a treatment position T, a monitoring position M and a travel position S.

[0057] Movement of the treatment head 1, emission of the HIFU beam by the transducer 4 and imaging of the tissue 7 and if need be of the tumour 8 as well as other functions are controlled by a control unit (not shown), which may be performed fully automatically, semi-automatically or manually, meaning that each step must be confirmed by an user person, or a combination thereof.

[0058] In the treatment position T, the focal point F of the HIFU beam is focused on the tumour 8, in order to treat the tumour 8.

[0059] In the monitoring position M, the treatment head 1 is lowered along an axis A with respect to the skin 6 compared to the treatment position T such that the distance between the imaging array 3 of the echography device 2 is as small as possible, thus increasing the image quality and reducing the appearance of skin artefacts known as skin ghost. The HIFU beam is not focused on the tumour 8.

[0060] In the travel position T, the treatment head 1 is raised along an axis A with respect to the skin 6 compared to the treatment position, whereby a contact between the membrane 5 and the skin 6 is kept in order to ensure coupling of the echography device 2 and cooling of the skin 6 and tissue 7. The HIFU beam is also not focused on the tumour 8. As an alternative, the pressure in the membrane may be adjusted in order to reduce friction, while keeping the treatment head 1 in a constant position. In another alternative, the membrane 5 or other equivalent means may be displaced with respect to the treatment head 1, which is kept in the same position. Combination of those alternatives may also be possible.

[0061] In FIG. 2, different displacing patterns of the treatment head 1 are schematically shown. The upper line indicates if the treatment head 1 is moving along a scanning pattern (“displace”) or is at rest (“stop”). The line in the middle indicates the position of the treatment head 1 along the axis A. The bottom line shows if the HIFU transducer 4 is operated (“ON”) or not (“OFF”).

[0062] The HIFU transducer 4 is located at a first treatment point I and is triggered to emit an HIFU beam and is successively moved along the scanning pattern in a plane substantially perpendicular to the axis A, referred to in FIG. 2 as the “scanning plane”, to reach the next treatment point II. During displacement from the treatment point I to the treatment point II, no displacement of the treatment head 1 along the axis A takes place. The treatment head 1 is kept in the treatment position T, as known from the prior art.

[0063] According to the present invention, before the treatment head 1 is displaced from the treatment point II to the treatment point III, the treatment head 1 is moved from the treatment position T to the travel position S along the axis A, then displaced along the scanning plane and subsequently moved back to the treatment position T, where a HIFU beam is emitted.

[0064] The treatment head 1 is then moved again from the treatment position T to the travel position S along the axis A and then displaced in the scanning plane from the treatment point III to the treatment point IV. The treatment head 1 is then moved from the travel position T to the monitoring position M along the axis A, where imaging of the tissue 7 and of the tumour 8 takes place, and further to the treatment position T along the axis A, where a HIFU beam is emitted. After emission of the HIFU beam, the treatment head 1 is moved again to the monitoring position M along the axis A for imaging the tissue 7 and tumour 8 and check the effect of the emitted HIFU beam.

[0065] The treatment head 1 is further moved to the travel position S along the axis A and displaced to the next treatment point V, where it is moved back along the axis A to the treatment position T and a HIFU beam is delivered.

[0066] When displacing the treatment head 1 from the treatment point V to the treatment point VI, the treatment head 1 is moved along the axis A from the treatment position T to the travel position S and then displaced in the scanning plane. The treatment head 1 is then moved to the monitoring position M along the axis A to perform imaging of the tissue 7 and tumour 8 and then to the treatment position T where a HIFU beam is emitted.

[0067] FIG. 3 shows an image treated with a method according to the present invention is shown.

[0068] The beginning of the image corresponding to the echography device 2 is the upper edge of the image. The width of the analyzed sector ranges from x.sub.min to x.sub.max.

[0069] The skin 6 is displayed as a thick bright curved line, the tumour 8 as a black surface about in the middle of the image. In the upper part of the image between the beginning of the image and the skin 6, the coupling fluid is displayed as a dark surface.

[0070] In the lower part of the tumour 8, a second bright curved line 9 running parallel to the skin 6 is displayed. This curved line is referred to as a skin ghost and covers a sector of the tumour 8, thus impeding correct imaging of the tissue 7.

[0071] After determination of the region corresponding to a run of the skin 6, which is done either manually or automatically by known techniques and is shown schematically by a curve 10, a distance y.sub.n between the beginning of the image and the line 10 is determined over the whole width of sector (from x.sub.min to x.sub.max). Then, a second line y.sub.s representing the skin ghost 9 is drawn at twice the distance y.sub.n from the beginning of the image. In FIG. 3, an offset A is set to zero.

[0072] This helps in improving recognition of the skin ghost 9. In case the skin ghost 9 overlaps the tumour 8, the treatment head 1 may be moved along the axis A in order to shift the skin ghost 9 downward and allow imaging of the whole tumour 8.