METHOD AND DEVICE FOR THE OBJECTIVE CHARACTERIZATION OF SYMPTOMS OF PARKINSON'S DISEASE

Abstract

A method and a system are described for performing an objective characterization of symptoms of the Parkinson's disease, through an analysis of the motion status of patients, wherein said motion status can be in one of the following phases: OFF phase, wherein Parkinson's symptoms, such as rigidity, tremor and bradykinesia, emerge; ON phase wherein the symptoms markedly improve; DIS phase wherein involuntary movements emerge, called dyskinesias; as detectors of the symptoms the following are used: voice analysis, face analysis, tremor analysis and movement analysis of said patient, an algorithm being provided adapted to use the detecting parameters to determine the motion status of the patient.

Claims

1. A method for performing an objective characterization of symptoms of Parkinson's disease, comprising determining a motor status of a patient affected by said Parkinson's disease, wherein said motor status can be in one of the following phases: OFF phase, wherein Parkinson's symptoms, comprising one or more of rigidity, tremor and bradykinesia, emerge; ON phase, wherein said symptoms markedly improve; DYS phase, wherein involuntary movements emerge, called dyskinesias; wherein said method uses as detectors of said symptoms: voice analysis, face analysis, tremor analysis and movement analysis of said patient, wherein an algorithm is provided that is adapted to use said detecting parameters to determine the motor status of said patient.

2. A system for the objective characterization of symptoms of Parkinson's disease, comprising: an electronic bracelet, equipped with an accelerometer, a magnetometer and a gyroscope, three-axial, for collecting data continuously about tremor and movement; a photo-camera to shoot face expressions, to be actuated upon request of a patient; a recorder to record the patient voice, to be actuated upon request of the patient; a processing device, equipped with a suitable software which, using a suitable algorithm, integrates data about movement, tremor, face and voice to identify a motor status of the patient affected by Parkinson's disease, comprising ON, OFF, and DYS; a display on which the motor status of the patient is displayed.

3. The system for the objective characterization of symptoms of Parkinson's disease according to claim 2, wherein said photo-camera, said recorder, said processing device, said display and the related software are integrated in a handheld computer/smartphone, so that the electronic bracelet sends combined data about analysis of movement and tremor directly to said handheld computer/smartphone, said handheld computer/smartphone being equipped with a display adapted to display the motor motion status of the patient: ON, OFF, DYS.

Description

[0024] The present invention will be better described by a preferred embodiment, given by way of non-limiting example, with reference to the attached drawings, in which:

[0025] FIG. 1 shows a system for the objective characterization of the symptoms of Parkinson's disease, according to the invention;

[0026] FIG. 2 shows a variant of the system according to the invention.

[0027] With reference to FIG. 1, the system (1) for the objective characterization of symptoms of Parkinson's disease includes: [0028] an electronic bracelet (2), equipped with an accelerometer, a magnetometer and a triaxial gyroscope, used to continuously collect data on tremor and movement; [0029] a camera (3) for recording facial expressions, to be activated at the request of the patient; [0030] a recorder (4) to record the voice to be activated at the request of the patient; [0031] a processing device (5), equipped with suitable software which, using a special algorithm, integrates movement, tremor, facial and vocal data to identify the motor state of the patient suffering from Parkinson's disease (ON, OFF, DIS); [0032] a display (6) showing the patient's motor status (ON, OFF, DIS).

[0033] This system is used for the objective characterization of the symptoms of Parkinson's disease.

[0034] The operation of the system (1) is divided into the following steps.

[0035] Step 1—The electronic bracelet (2) continuously records the patient's movement (10) and tremor (11) data.

[0036] Step 2—When the patient perceives a state of OFF or marked dyskinesias (DIS), he uses the camera (3) to capture facial expressions and the recorder (4) to record his voice.

[0037] Step 3—The processing device (5) receives from the electronic bracelet (2), the camera (3) and the recorder (4) the combined data of movement (10), tremor (11), facial images (12) and item (13) and, through the motor state characterization algorithm, identifies the patient's motor state (14) and displays it on the display (6): ON, OFF, DIS.

[0038] According to a preferred embodiment (la) shown in FIG. 2, the camera (3), the recorder (4), the processing device (5), the display (6) and the related software are integrated in a PDA/smartphone (7), for which the electronic bracelet (2) sends the combined analysis data of movement (10) and tremor (11) directly to the PDA/smartphone (7), which carries out the analysis by applying the motor status characterization algorithm indicates on its display the patient's motor status: ON, OFF, DIS.