RHINOMANOMETRY DEVICE

Abstract

A rhinomanometry device including: a measurement device for measuring at least one set of values of one or more parameters relating to a respiratory function of the nose of a patient; a memory for storing measurement values; a processing and control device for processing an output of the measurement device, the processing and control device to: determine if the set of measured values satisfies at least a first predetermined criterion; control the memory to store the set of measured values, and control the measurement device to stop the measurement in response to determining that the set of measured values satisfies at least a second predetermined criterion.

Claims

1. A rhinomanometry device comprising: a measurement device adapted to measure a set of values of one or more parameters relating to a respiratory function of nose of a patient; a memory for storing measurement values; a processing and control device for processing an output of the measurement device, the processing and control device being configured to: determine if the set of measured values satisfies at least a first predetermined criterion; control the memory to store the set of measured values, and control the measurement device to stop the measurement in response to determining that the set of measured values satisfies at least a second predetermined criterion.

2. The rhinomanometry device of claim 1, wherein there are a plurality of sets of measured values, and each said set of measured values corresponds to a measuring period defined by an inhalation phase and an exhalation phase.

3. The rhinomanometry device of claim 2, wherein said parameters include at least one of volume flow or pressure of air in the nose of the patient.

4. The rhinomanometry device of claim 3, wherein said first criterion includes one or more thresholds for at least one of the volume flow or the pressure of air in the nose of the patient or a duration of the measuring period.

5. The rhinomanometry device of claim 4, wherein the processing and control device is configured to at least one of: determine a maximum of the volume flow of air in the nose of the patient during the inhalation phase, wherein said first criterion is satisfied if a maximum of the volume flow exceeds a predetermined first threshold, or determine a minimum of the volume flow of air in the nose of the patient during the exhalation phase, wherein said first criterion is satisfied if the minimum of the volume flow falls below a predetermined second threshold.

6. The rhinomanometry device of claim 5, wherein said first criterion is satisfied if the duration of the measurement period exceeds a predetermined third threshold.

7. The rhinomanometry device of claim 6, wherein at least one of: the first threshold is at least 30 ccm/s, and can reach a threshold of up to 600 ccm/s or 50% of a maximum scale value, the second threshold is less than −30 ccm/s, and can reach a threshold of down to −600 ccm/s or 50% of a minimum scale value, or the third threshold is at least 0.5 and can reach a threshold of up to 5s.

8. The rhinomanometry device of claim 7, wherein the processing and control device is configured to determine a deviation of one or more or all of a newly measured set of values with one or more values from a previously measured set of values, and the second criterion is satisfied if the deviation is below a predetermined fourth threshold.

9. The rhinomanometry device of claim 8, wherein the processing and control device is configured to determine the deviation of one or more or all of a newly measured set of values with one or more values from each of at least the two or three last-measured sets of values, the second criterion is satisfied if the deviation in respect of each of the at least two or three last-measured sets of values is below the fourth threshold, and the fourth threshold is less than 50%.

10. The rhinomanometry device of claim 9, wherein the second criterion is satisfied if at least one of the maxima or minima of at least one of the volume flow or the duration of the combined inhalation and exhalation phases included in or represented by respective ones of the stored sets of measured values do not deviate from one another by more than the fourth threshold.

11. The rhinomanometry device of claim 1, further comprising an input device for at least one of entering or adjusting the parameters defining said first and second criteria.

12. The rhinomanometry device of claim 1, further comprising an input device configured to enable a user to manually stop the measurement, and in response to a manual stop, the processing and control device is configured to control the memory to store the last set of measured values prior to the manual stop that represents a full measuring period.

13. The rhinomanometry device of claim 12, wherein, in response to a manual stop, the processing and control device is configured to determine if at least the two last sets of measured values prior to the manual stop satisfy the second criterion, and to control the memory to store the at least two last sets of measured values in response to determining that the second criterion is satisfied.

14. The rhinomanometry device of claim 1, wherein the parameters are adapted to include the volume flow and pressure of air in the nose of the patient, and the measurement device is configured to measure a plurality of said parameter values over a period of time corresponding to an inhalation phase, and wherein the processing and control device is to determine: a first maximum value corresponding to a maximum of measured volume flow values; a second maximum value corresponding to a maximum of measured pressure values; a first value corresponding to an area of a rectangle defined by said first and second maximum values, a zero volume flow value and a zero pressure value; and a second value corresponding to an integration of an area under a curve defined by consecutive values of the volume flow over the pressure between a zero pressure value and the maximum pressure value; a third value corresponding to an integration of an area under a curve defined by consecutive values of the volume flow over the pressure between the maximum pressure value and the zero pressure value; a fourth value corresponding to a difference between the second and third values; a fifth value corresponding to a difference between the first and fourth values; and an output value corresponding to a ratio of the first and fifth values; and an output device configured to generate an output signal indicative of the output value.

15. A rhinomanometry device comprising: a measurement device configured to measure values of one or more parameters relating to a respiratory function of a nose of a patient, wherein the parameters include a volume flow and pressure of air in the nose of the patient, and the measurement device is configured to measure a plurality of said parameter values over a period of time corresponding to an inhalation phase; a processing device for processing an output of the measurement device to determine: a first maximum value corresponding to a maximum of measured volume flow values; a second maximum value corresponding to a maximum of measured pressure values; a first value corresponding to an area of a rectangle defined by said first and second maximum values, a zero volume flow value and a zero pressure value; and a second value corresponding to an integration of an area under a curve formed by consecutive values of the volume flow over the pressure between a zero pressure value and the maximum pressure value; a third value corresponding to an integration of the area under a curve formed by consecutive values of the volume flow over the pressure between the maximum pressure value and the zero pressure value; a fourth value corresponding to a difference between the second and third values; a fifth value corresponding to a difference between the first and fourth values; and an output value corresponding to a ratio of the first and fifth values; and an output device configured to generate an output signal indicative of the output value.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0019] The present invention may be better understood from reading the following description of non-limiting embodiments, with reference to the attached drawings, wherein:

[0020] FIG. 1 schematically shows a rhinomanometry device in accordance with an embodiment of the present invention;

[0021] FIGS. 2A and 2B illustrate diagrams of volume flow and pressure values from exemplary measurements using the rhinomanometry device of FIG. 1; and

[0022] FIGS. 3A and 3B illustrate diagrams of the volume flow over the pressure of an exemplary averaged measurement using the rhinomanometry device of FIG. 1.

DETAILED DESCRIPTION

[0023] FIG. 1 schematically shows a rhinomanometry device 1 in accordance with an embodiment of the present invention. The rhinomanometry device 1 comprises a rhinomanometer 2 to measure the volume flow and the pressure of air in the nose of a patient. The rhinomanometry device 1 also comprises a computer 3 that is connected to the rhinomanometer 2. The computer 3 that is adapted to process and store measurement values from rhinomanometer 2. The computer 3 comprises a display 4 for displaying the measurement values to a user.

[0024] Rhinomanometers are known as such and therefore not describe herein.

[0025] In operation, the rhinomanometry device 1 measures and records a sequence of values of the volume flow and the pressure of air in the nose of a patient. For example, the volume flow and pressure of air can be measured every 5 ms. The measurement frequency is adjustable.

[0026] Each breath consists of an inhalation and an exhalation and includes a plurality of measurement values of the volume flow and the pressure. At the end of each breath, the volume flow of the air, coming from a negative value, becomes zero, i.e. crosses the x-axis of a diagram representing the volume flow of air over time.

[0027] FIGS. 2A and 2B illustrate diagrams of volume flow and pressure values, respectively, from exemplary measurements. FIG. 2A illustrates the volume flow of air over four breaths. FIG. 2B illustrates the pressure of air over the same period.

[0028] For each breath, the maxima and minima of the volume flow and pressure are determined. In addition, the duration of each breath is determined. Measurements that satisfy predetermined criteria are added to a list of records representing “good” breaths, i.e. breaths that enable a practitioner to diagnose the condition of the patient's respiratory system. In an exemplary embodiment, these criteria are satisfied if the duration of the breath is at least 1s, the maximum volume flow during inhalation is at least 50 ccm/s and the minimum volume flow during exhalation is −50 ccm/s or less.

[0029] Measurements of a subsequent breath are added to the list if the above criteria are met and, additionally, there is a sufficient similarity with the measurements of one or more previous breaths. In an exemplary embodiment, there is sufficient similarity if the duration as well as the maximum and minimum volume flows do not vary by more than 30%.

[0030] If a predetermined number of consecutive breaths satisfy the above criteria, the measurement is stopped. For example, if three consecutive breaths are sufficiently similar to one another, then the corresponding measurements are “approved” and the measurement is terminated. The measurement values of the approved measurements can then be displayed for further use, e.g. diagnosis by a practitioner.

[0031] In an embodiment of the invention, the measurement values are processed to determine a Nasal Valve Index (NVI). In a first step, the measurement values of the approved measurements are averaged, thereby to determine an average set of values corresponding to one breath. This set of values is divided in two sub-sets corresponding to the inhalation and the exhalation phase of the breath, respectively. This is done on the basis of the zero-point of the volume flow. For determining the NVI, only the measurement values of the inhalation phase are used. The inhalation phase is further sub-divided into two portions, a first portion corresponding to the phase before the maximum pressure value within the inhalation phase is attained, and a second portion corresponding to the phase after the maximum pressure value within the inhalation phase is attained.

[0032] FIGS. 3A and 3B illustrate diagrams of the volume flow over the pressure of an exemplary measurement averaged as described above. The curves in the first quadrant of the diagram represent the measurement values of the inhalation phase.

[0033] In order to determine the NVI, the areas underneath the curves corresponding to the above-mentioned first and second portions of the inhalation phase are determined and subtracted from one another. The result corresponds to the highlighted area between the curves shown in FIG. 3B.

[0034] The ratio of this area to the total area corresponding to the rectangle in FIG. 3B, i.e. the maximum pressure multiplied with the maximum volume flow at the maximum pressure, when represented as a percentage, results in the NVI.

[0035] The NVI is independent of time and absolute volume flow and pressure values. Instead, the NVI indicates the deviation of the curves from one another before and after the maximum pressure value. It has been found that the NVI constitutes a useful and reliable representation of the state of a patient's respiratory system.

[0036] The description of embodiments has been presented for purposes of illustration and description. Suitable modifications and variations to the embodiments may be performed in light of the above without departing from the scope of protection as determined by the claims.