WOUND DRESSING DEVICE, ASSEMBLY AND METHOD

Abstract

Device, method and assembly for wound treatment. Specifically a wound dressing device; an assembly, e.g. a kit-of-parts, including the device as a component; and method of wound dressing and use wherein the device is a key component. The device includes a cavity defined by concave walls surrounded by lips for attachment to skin in fluid tight manner and a closure removably fixed to the lips and sealing the cavity. The assembly also includes, as another component a device for introducing blood into the cavity after it is fixed over a wound to permit the blood to clot over the wound within the cavity. In use, the clotting mold device is fixed on top of a wound, and blood is introduced into the mold space to permit the blood to clot within the mold space to form a blood clot over the wound.

Claims

1.-8. (canceled)

9. A method for dressing a wound, comprising: fixing a clotting mold device on top the wound, said device comprises a cavity surrounded by lips that are configured for attachment to skin in a fluid tight manner, and said fixing comprises attaching the lips to skin portions surrounding the wound to thereby form a mold space defined between the wound and the cavity; introducing blood into the mold space and permitting the blood to clot within the mold space to thereby form a blood clot over the wound; and maintaining the blood clot over the wound for a wound-healing period.

10. The method of claim 9, wherein said fixing comprise adhering the lips onto said skin portions.

11. The method of claim 10, wherein the lips comprises said adhesive or said adhesive is fitted onto said lips or onto said skin portions prior to said fixing.

12. The method of claim 9, wherein said fixing comprises forming a vacuum within the mold space.

13. The method of claim 9, comprising combining the blood clot with a scaffold matrix prior to blood clot formation, such that said scaffold matrix becomes integrated within the formed blood clot.

14. The method of claim 13, wherein said scaffold matrix is fitted onto the wound prior to said fixing.

15. The method of claim 14, wherein said scaffold matrix is comprised within said cavity.

16. The method of claim 9, comprising following formation of the blood clot, removing said device off the wound; and fixing a dressing material, e.g. gauze, over the blood clot.

17. The method of claim 9, wherein said introducing comprises: piercing the walls by a needle; and injecting blood into said mold space through the needle.

18. The method of claim 9, wherein the blood is whole blood.

19. The method of claim 9, comprising contacting the blood with a coagulation initiator, said coagulation initiator is characterized by one of the following: is mixed with the blood prior to said introducing, is a priori present in the cavity, is added into said mold space prior to or after said introducing, and is incorporated into a scaffold matrix that is comprised within said cavity or fitted onto the wound prior to said fixing.

20. (canceled)

21. The method of claim 9, wherein said device comprises a closure, removably fixed to the lips and sealing the cavity, said closure is removed prior to said fixing.

22. A wound dressing assembly, comprising a clotting mold device comprising a cavity defined by concave walls surrounded by lips configured for attachment to skin in a fluid tight manner, wherein, for introducing blood into the cavity once said lips are attached to the skin, the concave walls of the clotting mold device comprise one of (i) a portion being pierceable and suitable for introducing blood into the cavity, and (ii) a port suitable for introducing said blood into the cavity, a device for introducing blood into the cavity after it is fixed over a wound to permit the blood to come into contact with the wound and to clot over the wound within said cavity; and a blood coagulation initiator.

23. The wound dressing assembly of claim 22, wherein the device comprises a closure removably fixed to the lips and sealing the cavity.

24.-26. (canceled)

27. The wound dressing assembly of claim 22, comprising a scaffold matrix configured for integration within the formed blood clot.

28. The wound dressing of assembly of claim 27, wherein the scaffold matrix is comprised within said cavity.

29. The wound dressing assembly of claim 22, comprising one or both of a syringe and a needle for piercing the walls and injection of the blood into the cavity, and a dressing material for fixing over the blood clot.

30. The wound dressing assembly of claim 22, wherein said coagulation initiator is in a form of a powder, granulate or solution suitable for mixing with the blood or for applying directly onto the wound, being a priori present in the cavity, being incorporated into a scaffold matrix that is comprised within said cavity or intended for placement onto the wound prior to said attachment.

31. The wound dressing assembly of claim 22, wherein the walls of the cavity comprise one or both of a vent that is a priori sealed, for removal of excess pressure during introduction of the blood into the enclosure, and a port for introducing blood into the mold space.

32. The wound dressing assembly of claim 22, wherein the enclosure is made of a material to which a blood clot does not adhere.

33.-34. (canceled)

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to better understand the subject matter that is disclosed herein and to exemplify how it may be carried out in practice, embodiments will now be described, by way of non-limiting example only, with reference to the accompanying drawings, in which:

[0024] FIG. 1 shows a wound dressing device according to an embodiment of this disclosure.

[0025] FIG. 2 shows the wound dressing device after removal of the closure and applied onto the skin.

[0026] FIGS. 3A and 3B show, respectively, two steps of introducing blood into the mold space.

[0027] FIG. 4 shows the wound dressing device with blood still in liquid form with the device secured by adhesive tape to the skin.

[0028] FIG. 5 shows the blood clot with the device partially ruptured prior to removal.

[0029] FIG. 6 shows the blood clot on the skin after its formation and after the device has been removed.

DETAILED DESCRIPTION OF EMBODIMENTS

[0030] The invention will now be illustrated with reference to embodiments shown in the annexed Figures. It should be noted that these Figures are pictures from a test trial on skin without a wound, to demonstrate the wound dressing procedure of this disclosure.

[0031] The device 100 shown in FIG. 1 includes generally concave walls 102 that form a cavity 104 defined between lips 106 that are generally flat. The opening defined between the lips is sealed by a removable closure 108 which is a laminate/film fitted onto lips 106. After removal of closure 108, the device 100 is placed onto skin, an adhesive remaining after removal of the closure causes it to adhere to the skin. A device 100 fixed to a subject's skin is shown in FIG. 2.

[0032] Also shown in FIG. 1 is a scaffold matrix 112 placed within the cavity, the scaffold matrix holds a coagulation initiator 110.

[0033] Turning now to FIGS. 3A-3B, steps of introducing blood, typically whole blood into the mold space are shown. Specifically, blood withdrawn from the subject or alternatively taken from a blood bank, is injected with a needle 120 into the mold space formed between the walls 102 and underlying portion of the skin or wound. According to this non-limiting embodiment, upon introduction into the mold space, the blood is mixed with the coagulation initiator 110 a priori present in the cavity. The needle 120 first pierces the walls of the device and then injects the blood contained in the syringe (not seen).

[0034] In some other embodiments, the blood is pre-mixed with a coagulation initiator, such as Kaolin, that is provided in a separate container (not shown), or the coagulation initiator is introduced into the mold space separately, either before, during or after the blood introduction.

[0035] As can also be seen in FIGS. 1-3B the walls of the device are transparent to permit monitoring the introduction and subsequent blood clotting.

[0036] The device is then allowed to remain attached to the skin with the blood held within the mold space for a time at least until the blood has clotted. Such time may range from several days, to one or more weeks, The device can be secured to the skin by use of an adhesive strip 130, as seen in FIG. 4.

[0037] After a period of time, a blood clot is formed and the walls of the device can then be cut away, as seen in FIG. 5; and, after removal, a blood clot 140 remains on top of the skin, as seen in FIG. 6. Where the procedure will be performed over a wound, the blood clot will cover the wound and a dressing material, which may be conventional dressing material, such as gauze or bandage, will be applied over the clot for protecting the wound and securing the clot in place.