B1 FIELD MAP WITH CONTRAST MEDIUM INJECTION

20190336082 · 2019-11-07

    Inventors

    Cpc classification

    International classification

    Abstract

    A method is provided for determining a movement-corrected B1 field map on contrast medium injection, wherein before the injection, a B1 field map is determined. Following the contrast medium administration, a position change is determined at the position at which the B1 field map was determined. With the position change and the B1 field map, the movement-corrected B1 field map is determined.

    Claims

    1. A method for recording magnetic resonance (MR) signals from a person under examination in a MR system, wherein a contrast medium is injected into the person under examination, the method comprising: recording MR signals in a first scan portion for generating a first B1 field map of the person under examination before contrast medium administration; determining a position of the person under examination in the MR system before the contrast medium administration; recording MR signals in a second scan portion after the contrast medium administration, with which a dynamic contrast medium distribution in the person under examination is configured to be acquired; recording MR signals in a third scan portion for determination of a position of the person under examination in the MR system after the contrast medium administration received by the person under examination during the third scan portion; determining a position change of the person under examination between the position of the person under examination before the contrast medium administration and the position of the person under examination after the contrast medium administration; correcting the first B1 field map using the determined movement change to provide a movement-corrected B1 field map; recording MR signals in a fourth scan portion; and processing the MR signals of the fourth scan portion with the movement-corrected B1 field map.

    2. The method of claim 1, wherein the MR signals in the fourth scan portion are recorded to generate at least one quantitative physiological MR parameter map of the person under examination.

    3. The method of claim 2, wherein, during the recording of the MR signals in the third scan portion, MR profile scans are carried out in different spatial directions, wherein each MR profile scan has a projection of the MR signals of the person under examination into one spatial direction of the different spatial directions.

    4. The method of claim 3, wherein the position of the person under examination before the contrast medium administration is determined based on the first B1 field map of the person under examination, and wherein the movement change of the person under examination is determined from a difference of the position of the person under examination before and after the contrast medium administration.

    5. The method of claim 1, wherein, during the recording of the MR signals in the third scan portion, MR profile scans are carried out in different spatial directions, wherein each MR profile scan has a projection of the MR signals of the person under examination into one spatial direction of the different spatial directions.

    6. The method of claim 1, further comprising: recording MR signals in a fifth scan portion before the contrast medium administration for the determination of the position of the person under examination in the MR system before the contrast medium administration, wherein the movement change of the person under examination is determined from a position difference of the position of the person under examination before and after the contrast medium administration.

    7. The method of claim 6, wherein, in the fifth scan portion, MR profile scans are carried out in different spatial directions, and wherein each profile scan has a projection of the MR signals of the person under examination into one spatial direction of the different spatial directions.

    8. The method of claim 1, wherein the position of the person under examination before the contrast medium administration is determined based on the first B1 field map of the person under examination, and wherein the movement change of the person under examination is determined from a difference of the position of the person under examination before and after the contrast medium administration.

    9. The method of claim 1, further comprising: determining a transformation matrix from the position change of the person under examination, wherein the transformation matrix is applied to the first B1 field map for determining the movement-corrected B1 field map.

    10. The method of claim 1, wherein the third scan portion is recorded immediately before the fourth scan portion or during the fourth scan portion.

    11. The method of claim 1, further comprising: recording MR signals, before the contrast medium administration, in a comparison scan portion with at least one imaging sequence corresponding to an imaging sequence used in the second scan portion for obtaining the dynamic contrast medium distribution.

    12. A magnetic resonance (MR) system configured to record MR signals from a person under examination, wherein a contrast medium is configured to be injected into the person under examination, wherein the MR system comprises at least one receiving coil for recording MR signals, a control unit, and a memory unit, wherein the memory unit stores control information items executable by the control unit, and wherein the MR system, on execution of the control information items in the control unit, is configured to: record MR signals in a first scan portion for generating a first B1 field map of the person under examination before the contrast medium administration, determine a position of the person under examination in the MR system before the contrast medium administration, record MR signals in a second scan portion after the contrast medium administration, with which a dynamic contrast medium distribution in the person under examination is configured to be acquired; record MR signals in a third scan portion for the determination of a position of the person under examination in the MR system after the contrast medium administration received by the person under examination takes during the third scan portion; determine a movement change of the person under examination between the position of the person under examination before the contrast medium administration and the position of the person under examination after the contrast medium administration; correct the first B1 field map using the determined movement change to provide a movement-corrected B1 field map; record MR signals in a fourth scan portion; and process the MR signals of the fourth scan portion with the movement-corrected B1 field map.

    13. The MR system of claim 10, wherein the MR system, on execution of the control information in the control unit, is further configured to: record MR signals in a fifth scan portion before the contrast medium administration for the determination of the position of the person under examination in the MR system before the contrast medium administration, wherein the movement change of the person under examination is determined from a position difference of the position of the person under examination before and after the contrast medium administration.

    14. The MR system of claim 10, wherein the MR system, on execution of the control information in the control unit, is further configured to: determine a transformation matrix from the position change of the person under examination, wherein the transformation matrix is applied to the first B1 field map for determining the movement-corrected B1 field map.

    15. The MR system of claim 10, wherein the MR system, on execution of the control information in the control unit, is further configured to: recording MR signals, before the contrast medium administration, in a comparison scan portion with at least one imaging sequence corresponding to an imaging sequence used in the second scan portion for obtaining the dynamic contrast medium distribution.

    16. A computer program product comprising program code, wherein the computer program product is directly loadable into a memory unit of a control unit of a magnetic resonance (MR) system, wherein the computer program product, when executed in the control unit, is configured to cause the MR system to: record MR signals in a first scan portion for generating a first B1 field map of the person under examination before the contrast medium administration, determine a position of the person under examination in the MR system before the contrast medium administration, record MR signals in a second scan portion after the contrast medium administration, with which a dynamic contrast medium distribution in the person under examination is configured to be acquired; record MR signals in a third scan portion for the determination of a position of the person under examination in the MR system after the contrast medium administration received by the person under examination takes during the third scan portion; determine a movement change of the person under examination between the position of the person under examination before the contrast medium administration and the position of the person under examination after the contrast medium administration; correct the first B1 field map using the determined movement change to provide a movement-corrected B1 field map; record MR signals in a fourth scan portion; and process the MR signals of the fourth scan portion with the movement-corrected B1 field map.

    Description

    BRIEF DESCRIPTION OF THE DRAWINGS

    [0022] The disclosure will now be described in greater detail, referring to the accompanying drawings.

    [0023] FIG. 1 depicts a schematic representation of an example of a MR system with which the B1 field maps may be calculated following contrast medium administration.

    [0024] FIG. 2 depicts a schematic representation of a flow diagram with the use of a B1 map according to the prior art.

    [0025] FIG. 3 depicts an example of a flow diagram for the recording of MR signals with a contrast medium injection and the calculation of a movement-corrected B1 field map.

    [0026] FIG. 4 depicts a schematic representation of an example of a flow diagram with the acts that may be carried out for determining a B1 field map during the use of contrast medium.

    DETAILED DESCRIPTION

    [0027] The present disclosure will now be described in greater detail based on certain embodiments, referring to the accompanying drawings. In the drawings, the same reference signs denote the same or similar elements. Furthermore, the drawings are schematic representations of different embodiments of the disclosure and the elements shown in the figures are not necessarily shown to scale. Rather, the elements shown in the drawings are reproduced so that their function and purpose are comprehensible to a person skilled in the art. The connections shown in the figures between the functional units or other elements may also be implemented as an indirect connection, whereby a connection may be wireless or wire-connected. Functional units may be implemented as hardware, software or a combination of hardware and software.

    [0028] Shown schematically in FIG. 1 is a MR system with which, as described below, MR images of a person under examination 13 may be recorded, with contrast medium administration and determination of an accurate B1 field map.

    [0029] The MR system 9 has a magnet 10 for generating a polarization field BO wherein a person under examination 13 arranged on a support 12 is moved into the magnet 10 in order to record magnetic resonance signals from the person under examination 13 there. The coils 11 used for the signal recording represent the whole-body coil or the local coils that are utilized. By irradiation of high frequency (HF) pulses and the switching of magnetic field gradients, the magnetization created by the polarization field BO may be deflected out of the equilibrium position and positionally encoded and the resultant magnetization is detected by the receiving coils 11. How MR images may be generated by the irradiation of the HF pulses and by switching magnetic field gradients in different combinations and sequences is in principle known to persons skilled in the art and is not described in detail here.

    [0030] The MR system also has a control unit 20 which may be used for controlling the MR system 9. The control unit 20 has a high frequency (HF) control unit 14 and a gradient control unit 15 for controlling and switching the magnetic field gradient, wherein the HF control unit 14 is provided for the control and generation of the HF pulses for deflecting the magnetization. An image sequence control system 16 controls the sequence of the magnetic field gradients, the signal detection, and the HF pulses. By an input unit 17, an operator may control the MR system and on a display unit 18, the MR images or other information necessary for the control may be displayed. A computer unit 19 with at least one processor unit is provided for controlling the different units in the control unit 20. Furthermore, a memory unit 21 is provided in which, for example, program modules or programs may be stored which, when they are executed by the computer unit 19, may control the sequence of the MR system. The computer unit 19 may be configured, as described below, to create a movement-corrected B1 map following a contrast medium injection.

    [0031] FIG. 2 depicts schematically a sequence according to the prior art wherein the generated B1 field map has not provided satisfactory results in the whole person under examination 13 because the T1 time is partially shortened such that a B1 determination is no longer possible. In a scan portion 25, the recording of MR signals takes place before the contrast medium administration, and in a scan portion 26 following the contrast medium administration in portion 27, the repetition of the same scan takes place in order to receive information about the contrast medium progress in the person under examination 13. Subsequently, in a portion 28, there follows the actual MRF scan for the determination of the quantitative physiological MR parameters such as the T1 time, the T2 time or the proton density.

    [0032] In the portion 28 the recording of the MR signals for determining a B1 field map likewise takes place. In a method of this type, the contrast medium administration has shortened the T1 time to the extent that a scan of the B1 map is not possible in all regions of the person under examination 13.

    [0033] FIG. 3 depicts a scan sequence, showing how with contrast medium injection a B1 field map may nevertheless be calculated. In a first scan portion 31, the recording of MR signals takes place for generating a first B1 field map of the person under examination 13 before the contrast medium administration. How a B1 field map may be generated with the aid of MR signals is known to a person skilled in the art. For example, an equilibrium state at different repetition times TR is used, whereby this method places the signal in relation to both the repetition times, which depends on the tilt angle and thus enables the calculation of B1. Other methods for determining the B1 map are however known, but all the known methods may be used here. Finally, in a portion 32, the contrast medium administration takes place. Following the contrast medium administration in portion 32, a second scan portion 33 takes place for the reception of MR signals, in order to obtain information about the contrast medium distribution in the person under examination 13. Herein, in the second scan portion 33, the same image sequence may be used as in a comparison scan portion 34 which is carried out before the contrast medium administration. By comparison of the MR signals in the scan portions 33 and 34, the contrast medium distribution in the person under examination 13 may be determined. In the portions 33 and 34, different MR scans may be carried out, for example, fluid-attenuated scans or other scans. The imaging sequences may be the same in the scan portions 33 and 34. Following the second scan portion 33, in a third scan portion 35, the recording of MR signals for the determination of the position of the person under examination 13 in the MR system following contrast medium administration takes place. Subsequently, immediately thereafter, there follows the recording of the MR signals in the fourth scan portion 36, which is, for example, a MRF scan.

    [0034] For the determination of a position change between the first scan portion 31 in which the B1 field map has been calculated before the contrast medium administration, in a fifth scan portion 37, the position of the person under examination 13 before the contrast medium administration may be determined. In the scan portions 35 and 37, profiles may be recorded along the three spatial directions. The fifth scan portion 37 may be omitted if the position of the person under examination 13 may be directly estimated from the calculated B1 field map before the contrast medium administration.

    [0035] The B1 map recorded before the contrast medium administration during the first scan portion 31 has a temporal spacing from the fourth scan portion 36 which may lie in the region of several minutes. For this reason, the B1 field map calculated in portion 31 no longer fits to the scans in portion 36, due to the movements of the test person. In order to provide the accuracy of the B1 field map before the recording of the MR signals in the fourth scan portion, MR signals such as profile scans are recorded along the three spatial directions. These may be recorded within 1 second. Because the B1 map may cover the whole object, the B1 map may have a sharply defined edge. The profiles along the three spatial directions then show the change of the position of the person under examination 13 due to the movement, whereby with the changes, the B1 field map, which was recorded in the portion 31, may be corrected. With the aid of the MR signals in the portion 35, it is thus possible to generate a movement-corrected B1 field map which may then be used for post-processing the MR signals of the scan portion 36. The recording of the MR signals in the third scan portion 35 may also lie temporally within the fourth scan portion 36.

    [0036] With the sequence as set out in FIG. 3, it is possible, independently of the contrast medium administration, to cover T1 and T2 maps with a large value region. The movement-corrected B1 field map may be generated because the time point of the acquisition of the B1 field map is configured to the contrast medium administration. In order to enable the correct allocation, a movement correction is used in the largest possible recording region of the person under examination 13 in order to enable the transformation of the B1 field map to the movement-corrected B1 field map.

    [0037] FIG. 4 brings together some acts of the method described above. In act 41, the recording of the MR signals takes place in the first scan portion 31 for generating the first B1 field map of the person under examination 13 before the contrast medium administration. Following the contrast medium administration in the portion 32, the position of the person under examination 13 in the MR system may be calculated before the contrast medium administration in the act 42. This act 42 is not necessarily completed before the contrast medium administration but may also take place thereafter during the determination of the movement-corrected B1 field map. In act 43, the recording of the MR signals takes place in the second scan portion 33 in order to follow the contrast medium distribution in the person under examination 13. In act 44, MR signals are recorded in the third scan portion 35 in order to determine the position of the person under examination 13 in the MR system after contrast medium administration. This may be achieved, for example, by profile scans or other scans which enable a determination of the position of the person under examination 13 in the MR system. In act 45, the determination of the position change of the person under examination 13 between the position before the contrast medium administration and the position after the contrast medium administration takes place. Thus, in act 46, it is possible to correct the first B1 field map that was recorded and determined in act 41 for the determination of the movement-corrected B1 field map. In act 47, the recording of the MR signals takes place in the fourth scan portion 36, for example, to determine the physiological quantitative MR parameter maps, for example, a MRF scan. In act 48, the processing of the MR signals of the fourth scan portion with the movement-corrected B1 field map takes place, so that it is possible finally to determine the quantitative physiological MR parameter maps with a high degree of accuracy.

    [0038] Although the disclosure has been illustrated and described in detail by the exemplary embodiments, the disclosure is not restricted by the disclosed examples and the person skilled in the art may derive other variations from this without departing from the scope of protection of the disclosure. It is therefore intended that the foregoing description be regarded as illustrative rather than limiting, and that it be understood that all equivalents and/or combinations of embodiments are intended to be included in this description.

    [0039] It is to be understood that the elements and features recited in the appended claims may be combined in different ways to produce new claims that likewise fall within the scope of the present disclosure. Thus, whereas the dependent claims appended below depend from only a single independent or dependent claim, it is to be understood that these dependent claims may, alternatively, be made to depend in the alternative from any preceding or following claim, whether independent or dependent, and that such new combinations are to be understood as forming a part of the present specification.