CARDIAC HEALTH ASSESSMENT SYSTEMS AND METHODS
20220354432 · 2022-11-10
Inventors
Cpc classification
G16H10/65
PHYSICS
A61B5/7282
HUMAN NECESSITIES
A61B5/7475
HUMAN NECESSITIES
G16H50/20
PHYSICS
A61B5/08
HUMAN NECESSITIES
A61B5/7264
HUMAN NECESSITIES
G16H50/30
PHYSICS
G16H50/70
PHYSICS
A61B5/7275
HUMAN NECESSITIES
A61B5/0205
HUMAN NECESSITIES
A61B5/6898
HUMAN NECESSITIES
A61B5/7278
HUMAN NECESSITIES
A61B2562/0219
HUMAN NECESSITIES
A61B5/7435
HUMAN NECESSITIES
International classification
A61B5/00
HUMAN NECESSITIES
A61B5/0205
HUMAN NECESSITIES
A61B5/11
HUMAN NECESSITIES
G16H10/65
PHYSICS
G16H50/20
PHYSICS
G16H50/30
PHYSICS
Abstract
A cardiac health assessment system includes a memory, a circuit board, and a touchscreen controller integrated into a handheld electronic device (HED). The memory stores a classification model, a regression model, and instructions about a cardiac monitoring application. The circuit board includes a microphonic sensor, an Inertial Measurement Unit (IMU) sensor, a camera sensor, and a processor. The microphonic sensor captures cardiac sound wave signals indicative of the cardiac health of a user. The IMU sensor captures seismic signals indicative of the cardiac health of the user. The camera sensor enables visual data collection of tissue and photoplethysmography. The processor is configured to: execute the instructions, display commands to position the HED against the chest of the user, detect abnormal heart activity by deploying the classification model, and estimate intracardiac pressure by deploying the regression model. The touchscreen controller displays cardiac diagnostic information.
Claims
1. A cardiac health assessment system, comprising: a handheld electronic device (HED) comprising: a memory configured to store a classification model and/or a regression model, and a plurality of instructions for a cardiac monitoring application; a circuit board; a microphonic sensor in communication with the circuit board configured to capture cardiac sound wave signals indicative of the cardiac health of a user; an Inertial Measurement Unit sensor in communication with the circuit board for capturing seismic signals indicative of the cardiac health of the user; a camera sensor in communication with the circuit board to enable visual analysis of the user's tissue; a processor in communication with the circuit board configured to: execute the plurality of instructions for the cardiac monitoring application; display one or more commands to position the HED against the chest of the user; estimate intracardiac pressure by deploying the regression model; and a touchscreen controller in communication with the circuit board to display cardiac health information of the user.
2. The cardiac health assessment system as claimed in claim 1 further comprising a battery configured to supply electrical power to the HED.
3. The cardiac health assessment system of claim 1, wherein the HED has a curved shape adapted to fit firmly on the user's chest.
4. The cardiac health assessment system of claim 1, wherein the processor is configured to detect an abnormal heart activity arising from a plurality of parameters by deploying the classification model.
5. The cardiac health assessment system of claim 4, wherein the classification model has been trained to detect one or more of the following health conditions: hypertension, ischemic cardiomyopathy, heart arrythmias, aortic stenosis, aortic regurgitation, mitral stenosis and mitral regurgitation.
6. The cardiac health assessment system of claim 1, wherein the processor triggers a message transmission comprising of the user's data to another computing device.
7. The cardiac health assessment system of claim 1, wherein the processor identifies a plurality of unique physiological identification markers of the user based on the cardiac sound wave signals captured by the microphonic sensor.
8. The cardiac health assessment system of claim 1, wherein the processor is configured to present a plurality of instructions regarding the management of the user's disease.
9. The cardiac health assessment system of claim 1, wherein the classification model and the regression model are trained using intracardiac pressure data measured from one or more of the following: a catheter and an invasive sensor.
10. The cardiac health assessment system of claim 1, wherein the cardiac monitoring application is based on one or more of the following operating systems: Amazon Fire®, One UI®, Librem®, EMUI®, Android®, and iOS®.
11. The cardiac health assessment system of claim 1, further comprising a wearable device worn by the user to obtain physiological data of the user and transmit it to the HED over a network.
12. The cardiac health assessment system of claim 1, wherein the HED further comprises a diaphragm to enhance the cardiac audio signals captured by the microphonic sensor.
13. The cardiac health assessment system of claim 1, further comprising a soundwave transducer in communication with the circuit board for transmitting soundwaves into the body of the user to detect a plurality of physiological processes comprising intracardiac pressure and heart muscles.
14. The cardiac health assessment system of claim 1, further comprising a magnetometer in communication with the circuit board to detect abnormal traces of ferromagnetic levels in the blood of the user.
15. The cardiac health assessment system of claim 1, wherein the processor is further configured to display one or more commands for positioning the HED against the thoracic cage of the user.
16. The cardiac health assessment system of claim 1, wherein the processor is further configured to detect abnormal pulmonary health activity arising from a plurality of parameters by deploying a pulmonary disease classification model.
17. The cardiac health assessment system of claim 1, wherein the processor is further configured to display one or more commands for positioning the HED against a leg of the user.
18. The cardiac health assessment system of claim 1, wherein the processor is further configured to detect abnormal thrombotic activity arising from a plurality of parameters by deploying a deep vein thrombosis classification model.
19. The cardiac health assessment system of claim 1, wherein the processor is further configured to estimate lung fluid levels arising from a plurality of parameters by deploying a lung fluid estimation model.
20. The cardiac health assessment system of claim 1, further comprising a temperature sensor in communication with the circuit board for measuring one or more temperatures of the user.
21. The cardiac health assessment system of claim 1, wherein the processor is further configured to estimate patient hospitalization risk by deploying a patient risk stratification model.
22. A method for cardiac health assessment, comprising: integrating a memory, a circuit board, and a touchscreen controller in a handheld electronic device (HED); storing, in a memory, a classification model, a regression model, and a plurality of instructions for a cardiac monitoring application; wherein the circuit board is connected to a microphonic sensor, an Inertial Measurement Unit (IMU) sensor, a camera sensor, and a processor; capturing, by the microphonic sensor, cardiac sound wave signals indicative of the cardiac health of a user; capturing, by the IMU sensor, seismic signals indicative of the cardiac health of the user; performing, by the camera sensor, visual data collection of tissue and photoplethysmography; executing, by the processor, the instructions pertaining to the cardiac monitoring application; displaying, by the processor, one or more commands to aid in the positioning of the HED against the chest of the user; estimating, by the processor, intracardiac pressure by deploying the regression model; and displaying, by the touchscreen controller, cardiac health information derived from the classification model and the regression model.
23. The method as claimed in claim 22 further comprising a step of supplying, by a battery, electrical power to the circuit board.
24. The method as claimed in claim 22, wherein the HED has a shape adapted to fit firmly on the user's chest.
25. The method as claimed in claim 22, wherein the processor triggers a message transmission to another computing device upon detection of a high severity of heart disease based on the estimation from the regression model.
26. The method as claimed in claim 22, wherein the method comprises detecting, by the processor, an abnormal heart activity arising from a plurality of parameters by deploying the classification model.
27. The method as claimed in claim 26, wherein the plurality of parameters comprise one or more of the following: hypertension, heart arrythmias, ischemic cardiomyopathy, aortic stenosis, aortic regurgitation, mitral stenosis, and mitral regurgitation.
28. The method as claimed in claim 22, wherein the processor identifies a plurality of unique physiological markers of the user based on cardiac sound wave signals captured by the microphonic sensor.
29. The method as claimed in claim 22, wherein the processor is configured to present a plurality of instructions regarding the management of the user's disease.
30. The method as claimed in claim 22, wherein the classification model and the regression model are trained by using intracardiac pressure data measured from one or more of the following: a catheter and an invasive sensor.
31. The method as claimed in claim 22, wherein the cardiac monitoring application is based on one or more of the following operating systems: Amazon Fire®, One UI®, Librem®, EMUI®, Android®, and iOS®.
32. The method as claimed in claim 22 further comprising a step of obtaining, by a wearable device worn by the user, physiological data of the user and transmitting it to the HED over a network.
33. The method as claimed in claim 22, wherein the cardiac audio signals captured by the microphonic sensor are enhanced by a diaphragm.
34. The method as claimed in claim 22, further comprising the step of transmitting sound waves into the body of the user to detect a plurality of physiological processes indicating intracardiac blood pressure and blood flow with the use of a sound transducer connected to the circuit board.
35. The method as claimed in claim 22, further comprising the step of detecting abnormal traces of ferromagnetic levels in the blood of the user using a magnetometer connected to the circuit board.
36. The method as claimed in claim 22, wherein the one or more commands displayed by the processor to aid in the positioning of the HED are used to aid the user in positioning the HED against the thoracic cage of the user.
37. The method as claimed in claim 22, further comprising the step of using the processor to detect abnormal pulmonary health activity arising from a plurality of parameters by deploying a pulmonary disease classification model
38. The method as claimed in claim 22, wherein the one or more commands displayed by the processor to aid in the positioning of the HED are used to aid the user in positioning the HED against the leg of the user.
39. The method as claimed in claim 22, further comprising the step of using the processor to detect abnormal thrombotic activity arising from a plurality of parameters by deploying a deep vein thrombosis classification model.
40. The method as claimed in claim 22, further comprising the step of using the processor to estimate lung fluid levels arising from a plurality of parameters by deploying a lung fluid estimation model.
41. The method as claimed in claim 22, further comprising the step of measuring one or more temperatures of the user with the use of a temperature sensor connected to the circuit board.
42. The method as claimed in claim 22, further comprising the step of using the processor to estimate patient hospitalization risk by deploying a patient risk stratification model.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
[0053] The accompanying drawings illustrate the embodiments of systems, methods, and other aspects of the disclosure. A person with ordinary skill in the art will appreciate that the illustrated element boundaries (e.g., boxes, groups of boxes, or other shapes) in the figures represent an example of the boundaries. In some examples, one element may be designed as multiple elements, or multiple elements may be designed as one element. In some examples, an element shown as an internal component of one element may be implemented as an external component in another and vice versa. Furthermore, the elements may not be drawn to scale.
[0054] Various embodiments are described in accordance with the appended drawings, which are provided to illustrate and not limit the scope of the claimed subject matter wherein similar designations denote similar elements, and in which:
[0055]
[0056]
[0057]
[0058]
DETAILED DESCRIPTION
[0059] The present description is best understood with reference to the detailed figures and description set forth herein. Various embodiments of the present systems and methods have been discussed with reference to the figures. However, those skilled in the art will readily appreciate that the detailed description provided herein with respect to the figures are merely for explanatory purposes, as the present systems and methods may extend beyond the described embodiments. For instance, the teachings presented and the needs of a particular application may yield multiple alternative and suitable approaches to implement the functionality of any detail of the present systems and methods described herein. Therefore, any approach to implement the disclosed systems and methods may extend beyond certain implementation choices in the following embodiments.
[0060] According to the described embodiments, the methods may be implemented by performing or completing manually, automatically, and/or a combination of thereof. The term “method” refers to manners, means, techniques, and procedures for accomplishing any task including, but not limited to, those manners, means, techniques, and procedures either known to a person skilled in the art or readily developed from existing manners, means, techniques and procedures by practitioners of the art to which the present invention belongs. A person skilled in the art will envision many other possible variations within the scope of the systems and methods described herein.
[0061]
[0062] In an embodiment, the plurality of instructions pertaining to a cardiac monitoring application may comprise but are not limited to information regarding how and when to execute the classification and regression models, what questions and how the user should be prompted with these questions, information regarding the detection of whether or not the HED has been correctly placed by the user, the prompts given to the user so that the user can log in with their credentials, information regarding ensuring that there are no cyber security risks present, and information regarding enabling data transmission and enabling connectivity with the wearable device coupled to the system. These instructions may take several forms, they may be simple decision rules and/or they may be adaptive to the use patterns of the user to ensure robustness across different users with different interpretations of the information that may be presented in the cardiac monitoring application.
[0063] In an embodiment, the cardiac monitoring application is based on one or more operating systems, for example operating systems such as Amazon Fire®, One UI®, Librem®, EMUI®, Android®, and iOS®. The cardiac health assessment system 100 allows the user to register with the cardiac monitoring application configured to operate within the HED 102. In an embodiment, the user may be required to answer a short questionnaire about their health. In some embodiments requested, information may be requested but not required from the user. A user may include a patient, a patient using the cardiac monitoring application using the HED 102 with their own body, and/or any other person such as a healthcare professional using the HED, for example using the HED to execute the functions of the embodiments with a patient.
[0064] The memory 104 may be a non-volatile memory or a volatile memory or any combination of these types of memory. Examples of non-volatile memory may include, but are not limited to flash memory, a Read Only Memory (ROM), a Programmable ROM (PROM), Erasable PROM (EPROM), and Electrically EPROM (EEPROM) memory. Examples of volatile memory may include but are not limited to Dynamic Random-Access Memory (DRAM), and Static Random-Access memory (SRAM).
[0065] The circuit board 106 includes a microphonic sensor 108, an Inertial Measurement Unit (IMU) sensor 110, a camera sensor 112, and a processor 114. In an embodiment, the circuit board 106 is referred to as a printed wiring board, printed wiring card, or a printed circuit board (PCB) that mechanically supports and electrically connects electrical or electronic components of the embodiments using conductive tracks, pads, and other features etched from one or more sheet layers of copper laminated onto and/or between sheet layers of a non-conductive substrate. The microphonic sensor 108 captures cardiac sound wave signals indicative of the cardiac health of a user and/or a patient. The IMU sensor 110 captures seismic signals indicative of the cardiac health of the user. The camera sensor 112 enables visual data collection of tissue and photoplethysmography. In an embodiment, the camera sensor 112 is a phone camera image sensor such as a CMOS image sensor.
[0066] The processor 114 is configured to: execute the plurality of instructions about the cardiac monitoring application; display one or more commands so that the HED 102 can be positioned against the chest of the user, detect an abnormal heart activity arising from a plurality of parameters by deploying the classification model; and estimate intracardiac pressure by deploying the regression model. In an embodiment, ejection fraction, cardiac output and blood pressure may be estimated by deploying the regression model. In an embodiment, the classification model, and the regression model are trained by using intracardiac pressure data measured from a catheter and/or an invasive pressure sensor which are considered the gold standard in the industry for measuring such types of data. According to several embodiments, gold standard ejection fraction data may comprise data obtained from an ultrasound analysis and/or cardiovascular magnetic resonance (CMR) that is used to train the classification model and regression model. According to many embodiments, gold standard cardiac output data may comprise data obtained from a Pulmonary Artery catheter-based thermodilution. According to many embodiments, gold standard blood pressure data may comprise data obtained from a sphygmomanometer and/or an arterial line.
[0067] Memory 104 is configured to register the user over the cardiac monitoring application by receiving one or more credentials from the user for providing access to the cardiac monitoring application. Examples of the credentials, include but are not limited to, a username, password, age, gender, phone number, email address, location, as well as any other suitable information. In several embodiments, the cardiac monitoring application is commercialized as a software application or a mobile application, a web application for cardiac health assessment or any combination of these.
[0068] The processor 114 may include at least one data processor for executing program components for executing user- or system-generated requests. Processor 114 may include specialized processing units such as integrated system (bus) controllers, memory management control units, floating point units, graphics processing units, digital signal processing units, etc. Processor 114 may include a microprocessor, such as AMD® ATHLON® microprocessor, DURON® microprocessor OR OPTERON® microprocessor, ARM's application, embedded or secure processors, IBM® POWERPC®, INTEL'S CORE® processor, ITANIUM® processor, XEON® processor, CELERON® processor or other line of processors, etc. Processor 114 may be implemented using mainframe, distributed processor, multi-core, parallel, grid, or other architectures. Some embodiments may utilize embedded technologies like application-specific integrated circuits (ASICs), digital signal processors (DSPs), Field Programmable Gate Arrays (FPGAs), and the like.
[0069] Processor 114 may be disposed of in communication with one or more input/output (I/O) devices via an I/O interface. I/O interface may employ communication protocols/methods such as, without limitation, audio, analog, digital, RCA, stereo, IEEE-1394, serial bus, universal serial bus (USB), infrared, PS/2, BNC, coaxial, component, composite, digital visual interface (DVI), high-definition multimedia interface (HDMI), RF antennas, S-Video, VGA, IEEE 802.n/b/g/n/x, Bluetooth, cellular (e.g., code-division multiple access (CDMA), high-speed packet access (HSPA+), global system for mobile communications (GSM), long-term evolution (LTE), WiMax, or the like), and the like.
[0070] In an embodiment, the processor 114 triggers a message transmission to a computing device, for instance a computing device used by a healthcare professional, upon detection of high severity of heart disease based on the cardiac signals captured by the HED. Examples of computing device include but are not limited to a laptop, a desktop, smartphone, a server, and any combination of these.
[0071] In several embodiments, the processor 114 identifies a plurality of unique physiological markers of the user based on historical cardiac signals captured by the HED 102. In an embodiment, processor 114 is configured to present a plurality of instructions regarding the management of the user's disease. The touchscreen controller 124 displays cardiac diagnostic information received from the HED 102 that is derived from the cardiac sensor signal data.
[0072] In an embodiment, the touchscreen controller 124 is a capacitive touch screen that uses the conductive touch of a human finger or a specialized input device. The touchscreen controller 124 provides a User Interface (UI) used by the user or an administrator to initiate a request to view the data assessed by the cardiac health assessment system and provide various inputs to the cardiac health assessment system 100. In many of the embodiments, the UI also known as a Graphic User Interface (GUI) is a convenient interface for accessing the information related to the status of the user's heart health. The touchscreen controller 124 may be operated by a display driver such as an LCD driver or a LED driver. In many embodiments, the touchscreen controller 124 includes an ASIC (application-specific integrated circuit) a digital signal processor (DSP) and/or any other suitable technology known to those skilled in the art.
[0073] In many embodiments, the plurality of parameters that may be sensed and/or monitored includes hypertension, atrial fibrillation, ischemic cardiomyopathy, aortic stenosis, aortic regurgitation, mitral stenosis, and/or mitral regurgitation. It is well-known that hypertension and atrial fibrillation can be detected using visual based analysis including but not limited to photoplethysmography and/or analyzing acoustic patterns related to irregular heartbeats and/or velocity of blood-flow and/or patterns related to pulse transmit time. It is further well known that ischemic cardiomyopathy, aortic stenosis, aortic regurgitation, mitral stenosis, regurgitation can result in abnormal seismic and/or acoustic activity that can be detected using inertial measurement units, microphonic sensors and/or other soundwave-based technologies such as ultrasound transceivers. These abnormal seismic and/or acoustic activities may results from arterial blockages and/or abnormal sounds relating to excess blood-flow from cardiac leakages between chambers in the heart. In some embodiments, the cardiac health assessment system 100 includes a battery 118 configured to supply electrical power to the circuit board 106. According to some embodiments, battery 118 is based on Lithium Polymer (Li-Poly) and Lithium-Ion (Li-Ion). In some embodiments, the battery 118 is operated by a power management integrated circuit such as power MOSFETs.
[0074]
[0075] In an embodiment, the circuit board 106 includes a diaphragm 116 to enhance the cardiac audio signals captured by the microphonic sensor.
[0076]
[0077] The method further comprises step 424 of obtaining, by a wearable device worn by the user, physiological data of the user and transmit it to the HED over a network. In many embodiments, the diaphragm enhances the cardiac audio signals captured by the microphonic sensor. Any other suitable signal enhancer known to those skilled in the art may be used to enhance the one or more signals in the embodiments. In many embodiments, the ultrasound transducer transmits high-frequency waves into the body of the user to deflect a plurality of physiological processes comprising intracardiac blood pressure and blood flow and return sound wave data to be analyzed with the classification model and the regression model. In some embodiments, the infrasound transducer transmits low-frequency waves into the body of the user to deflect the physiological processes and return wave data to be analyzed with the classification model and the regression model. In an embodiment, the magnetometer detects abnormal traces of ferromagnetic levels in the blood of the user.
[0078] Thus, embodiments of the cardiac health assessment systems and methods provide a real-time diagnostic mechanism for heart disease and heart failure. The cardiac monitoring application incorporates reminders, nudges, and notifications to help the heart patient to track the risk of heart diseases and progression of heart failure.
[0079] Accordingly, one advantage of the claimed subject matter is that it provides a telehealth mechanism to facilitate the user to interact with a clinician or get on a video call with the clinician.
[0080] Another advantage of the claimed subject matter is that the use of telehealth mechanism allows the user to interact with a medical chatbot.
[0081] Another advantage of the claimed subject matter is that the telehealth mechanism allows for remote patient monitoring and management of heart diseases and heart failure.
[0082] Another advantage of the claimed subject matter is that the telehealth mechanism allows for treatment and medication adjustments based on the results assessed by the HED.
[0083] In the foregoing specification, embodiments of the claimed subject matter have been described with reference to numerous specific details that may vary from implementation to implementation. The specification and drawings are, accordingly, to be regarded in an illustrative rather than a restrictive sense. The embodiments are only limited by the scope of the claimed subject matter.