BREATH TEST SYSTEM

Abstract

The invention relates to a breath test system that is unobtrusive in that it does not require a person subjected to the system to take any other action to breath. It comprises a sensor unit (5) configured to sense the presence or concentration of a volatile substance, present in air flowing through a predefined inlet area (4), and to generate a signal corresponding to the concentration of said substance. There is also provided an apparatus (2, 3) configured to detect the presence of a person at a position in the vicinity of said input area, and having means for registering said presence, and further configured to respond to said presence by delivering an output. This said apparatus includes a unit configured to call for immediate attention of said person, upon said registration of the presence of said person, and a unit configured to provide instructions to said person to direct an expiratory air flow towards said inlet area (4). An analyzer (10) for the determination of breath substance concentration of said person is also provided, the determination being based on said signal corresponding to the substance concentration.

Claims

1.-15. (canceled)

16. A breath test system for determining the concentration of a volatile substance present in a breath of air, said breath test system comprising: a chamber having an inlet for receiving a breath of air, an outlet, and a lumen extending between said inlet and said outlet; an electromagnetic emitter configured to emit light into said lumen of said chamber; at least one electromagnetic detector configured to detect light emitted by said electromagnetic emitter after said light has passed through said lumen, said at least one electromagnetic detector being configured to generate a signal corresponding to at least one characteristic of said light after said light has passed through said lumen and been received by said at least one electromagnetic detector; said light emitted by said electromagnetic emitter and detected by said at least one electromagnetic detector being directed along an optical path contained within said chamber; an analyzer for analyzing the signal generated by said at least one electromagnetic detector so as to determine (i) whether a breath of air has entered said lumen of said chamber; and (ii) if a breath of air has entered said lumen of said chamber, the concentration of the volatile substance present in a breath of air.

17. The breath test system according to claim 16, wherein said breath test system comprises a first electromagnetic detector providing a first signal corresponding to the concentration of the volatile substance within the breath of air and a second electromagnetic detector providing a second signal corresponding to the concentration of a tracer substance within the breath of air, said determination of the concentration of the volatile substance present in the breath of air taking said tracer substance concentration into account.

18. The breath test system according to claim 16, wherein said volatile substance is acetone, acetaldehyde, methanol, ethanol, carbon monoxide, methane, ethane, propane, pentane, hexane, heptane, octane, isoprene, ammonia, hydrogen sulfide, methyl mercaptan, ethyl acetate, dimethyl ether, diethyl ether, benzene, toluene, methyl ethyl ketone, or methyl isobutyl ketone or a combination thereof.

19. The breath test system according to claim 16, wherein a response time of said breath test system is shorter than one second.

20. The breath test system according to claim 16, wherein said system comprises registration means for registering the presence of a person in the vicinity of said inlet, wherein the registration means comprises a microphone, and means for identification of the person using voice recognition, and further wherein said system further comprises a camera or other optical detector, and means for identification of the person using image analysis, bar code reading or biometrics.

21. The breath test system according to claim 17, wherein said first electromagnetic detector and said second electromagnetic detector are based on substance-specific infrared absorption in predetermined wavelength bands, and further wherein said predetermined wavelength band for said first electromagnetic detector is 9.1-9.9 μm corresponding to ethyl alcohol, and said predetermined wavelength band for said second electromagnetic detector is 4.2-4.3 μm corresponding to CO.sub.2.

22. The breath test system according to claim 16, comprising means for active transport of air from said inlet to said at least one electromagnetic detector and said outlet.

23. The breath test system according to claim 16, wherein attention of a person is called for by coordinated flashing of a light, and a distinctive sound combined with a specific symbol or icon representing said breath test.

24. The breath test system according to claim 16, wherein said system is configured to provide instructions to a person in the vicinity of said inlet to direct a breath of air into said inlet such that the breath of air enters said lumen of said chamber, wherein said instructions are provided to the person verbally or as text message, step by step and with the level of detail provided to the person increasing with time.

25. The breath test system according to claim 16, wherein said breath test system further comprises a display for communicating messages of text, symbols, icons or images, or a loudspeaker for communicating recorded spoken messages, or symbolic sound tracks.

26. The breath test system according to claim 16, wherein said determination of the concentration of the volatile substance present in the breath of air accounts for quality criteria, wherein said quality criteria includes at least one of a concentration of tracer gas exceeding a predefined threshold and background variations of said signal being below a predefined upper limit.

27. The breath test system according to claim 16, wherein said system is integrated into the interior of the vehicle compartment or an entrance of building or a workplace.

28. The breath test system according to claim 16, wherein the total test time of said breath test system does not exceed five seconds.

29. The breath test system according to claim 16, further comprising capacitive and inductive electronic elements for protective purposes, and wherein said at least one electromagnetic detector and associated analog input stages is equipped with differential preamplifiers in order to suppress the influence of common mode interference.

30. The breath test system according to claim 16, wherein said breath test system is confined in a box adapted to be wall-mounted in such a way that means for registering a presence of a person and said inlet are located on one side of the box and thereby accessible through a hole in the wall to which said breath test system is mounted.

31. A method for determining the concentration of a volatile substance present in a breath of air, said method comprising: providing a breath test system comprising: a chamber having an inlet for receiving a breath of air, an outlet, and a lumen extending between said inlet and said outlet; an electromagnetic emitter configured to emit light into said lumen of said chamber; at least one electromagnetic detector configured to detect light emitted by said electromagnetic emitter after said light has passed through said lumen, said at least one electromagnetic detector being configured to generate a signal corresponding to at least one characteristic of said light after said light has passed through said lumen and been received by said at least one electromagnetic detector; said light emitted by said electromagnetic emitter and detected by said at least one electromagnetic detector being directed along an optical path contained within said chamber; an analyzer for analyzing the signal generated by said at least one electromagnetic detector so as to determine (i) whether a breath of air has entered said lumen of said chamber; and (ii) if a breath of air has entered said lumen of said chamber, the concentration of the volatile substance present in a breath of air; passing a breath of air into said lumen of said chamber; using said electromagnetic emitter to emit light into said lumen of said chamber such that said light passes through said breath of air in said lumen of said chamber, such that said light is detected by said at least one electromagnetic detector so as to generate said signal; analyzing said signal so as to determine (i) whether a breath of air has entered said lumen of said chamber; and (ii) if a breath of air has entered said lumen of said chamber, the concentration of the volatile substance present in a breath of air.

32. The method according to claim 31, wherein said breath test system comprises a first electromagnetic detector providing a first signal corresponding to the concentration of the volatile substance within the breath of air and a second electromagnetic detector providing a second signal corresponding to the concentration of a tracer substance within the breath of air, said determination of the concentration of the volatile substance present in the breath of air taking said tracer substance concentration into account.

33. The method according to claim 31, wherein said volatile substance is acetone, acetaldehyde, methanol, ethanol, carbon monoxide, methane, ethane, propane, pentane, hexane, heptane, octane, isoprene, ammonia, hydrogen sulfide, methyl mercaptan, ethyl acetate, dimethyl ether, diethyl ether, benzene, toluene, methyl ethyl ketone, or methyl isobutyl ketone or a combination thereof.

34. The method according to claim 31, wherein a response time of said breath test system is shorter than one second.

35. The method according to claim 31, wherein said system comprises registration means for registering the presence of a person in the vicinity of said inlet, wherein said registration means comprises a microphone, and means for identification of the person using voice recognition, and further wherein said system further comprises a camera or other optical detector, and means for identification of the person using image analysis, bar code reading or biometrics.

36. The method according to claim 32, wherein said first electromagnetic detector and said second electromagnetic detector are based on substance-specific infrared absorption in predetermined wavelength bands, and further wherein said predetermined wavelength band for said first electromagnetic detector is 9.1-9.9 μm corresponding to ethyl alcohol, and said predetermined wavelength band for said second electromagnetic detector is 4.2-4.3 μm corresponding to CO.sub.2.

37. The method according to claim 31, comprising means for active transport of air from said inlet to said at least one electromagnetic detector and said outlet.

38. The method according to claim 31, further comprising calling attention to a person, wherein the attention of the person is called for by coordinated flashing of a light, and a distinctive sound combined with a specific symbol or icon representing said breath test.

39. The method according to claim 31, wherein said method further comprises providing instructions to a person in the vicinity of said inlet to direct a breath of air into said inlet such that the breath of air enters said lumen of said chamber, wherein said instructions are provided to the person verbally or as text message, step by step and with the level of detail provided to the person increasing with time.

40. The method according to claim 31, wherein said breath test system further comprises a display for communicating messages of text, symbols, icons or images, or a loudspeaker for communicating recorded spoken messages, or symbolic sound tracks.

41. The method according to claim 31, wherein said determination of the concentration of the volatile substance present in the breath of air accounts for quality criteria, wherein said quality criteria includes at least one of a concentration of tracer gas exceeding a predefined threshold and background variations of said signal being below a predefined upper limit.

42. The method according to claim 31, wherein said system is integrated into the interior of the vehicle compartment or an entrance of building or a workplace.

43. The method according to claim 31, wherein the total test time of said breath test system does not exceed five seconds.

44. The method according to claim 31, further comprising capacitive and inductive electronic elements for protective purposes, and wherein said at least one electromagnetic detector and associated analog input stages is equipped with differential preamplifiers in order to suppress the influence of common mode interference.

45. The method according to claim 31, wherein said breath test system is confined in a box adapted to be wall-mounted in such a way that means for registering a presence of a person and said inlet are located on one side of the box and thereby accessible through a hole in the wall to which said breath test system is mounted.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0012] The invention will now be described below with reference to the drawings in which

[0013] FIG. 1 shows a schematic drawing of the system according to one embodiment.

[0014] FIG. 2 shows a flow graph of the system function.

[0015] FIG. 3a shows a time sequence of typical breath tests performed with the system according to the invention for an experienced person, and

[0016] FIG. 3b shows a time sequence of typical breath tests performed with the system according to the invention for an inexperienced person.

DETAILED DESCRIPTION

[0017] The present invention involves both physical attributes and functional characteristics, as evident both in the enclosed claims and the detailed description.

[0018] FIG. 1 is a schematic drawing (not to scale) of one embodiment of the system 1 according to the invention. The system 1 may be built into a separate physical enclosure, or being part of inventories, e.g. in a vehicle cabin. A test person 12 is shown positioned in the vicinity of an inlet area 4 of the sensor unit 5, equipped with a sensor element 8 generating a signal corresponding to the ethyl alcohol concentration of the air flowing through the inlet area 4. Means for active transport of air through the sensor unit 5 is provided by a fan or pump 9, preferably including means for controlling the volume flow. The inlet area 4 constitutes one or several openings, into which air can be freely flowing, or driven by the fan 9. Preferably, a particle filter 11 e.g. made from porous material is included in the inlet area 4. This prevents particles and aerosols from contaminating the sensor unit 5 while not impeding the air flow to any significant degree. When the person 12 is directing expiratory air towards the inlet area 4 from a distance not exceeding 50 cm, the air flowing through the sensor unit 5 will consist of a mixture of ambient and expiratory air from the person 12.

[0019] As already explained in the background, a central characteristic of the present system is to obtain cooperation with the person 11 during a short moment of time. The apparatus configured for achieving this includes means for registration 2 of the presence of a person 12 at a position in the vicinity of the inlet area 4, and an audiovisual unit 3. The implementation of the means of registration 2 is highly depending on the actual application and could include a microswitch indicating door opening/closure, microphone, camera, contactless detector using ultrasound or infrared radiation, force sensor responding to the weight of the person. It may include means for identification of the person by voice control, image analysis, barcode reading, or biometric analysis. The audiovisual unit 3 preferably includes a loudspeaker 3a and a display 3b. The loudspeaker 3a may generate artificial speech or symbolic sound tracks, and the display 3b may convey text, images, icons or other symbols.

[0020] Preferably, the audiovisual unit 3 is located in close vicinity to the inlet area 4 of the sensor unit 5, in order to direct the person's 12 attention to this area. It is capable of calling for the immediate attention of the person 12 upon presence registration or at some later instant. It is also capable of conveying an instruction, even a detailed one, in the case that the person 12 may need one.

[0021] The location of the audiovisual unit 3 in close vicinity to the inlet area 4 is particularly important in the case of an experienced but distracted or otherwise un-attentive person 12. When reminded by the signals from the audiovisual unit 3, the experienced person 12 will react with minimal time delay, and deliver a directed breath towards the inlet area 3. Alternative solutions would increase the mental load of the person 12.

[0022] From research in experimental psychology it is known that the reaction time of a person may vary from 0.2 to several seconds depending on the degree of distraction, mental load, and choice options. The capability of the present invention to both call for and direct the attention of the experienced person 12 to the sensor inlet area is thus highly important in order to save time.

[0023] As a consequence of mixing between ambient and expiratory air, the signal generated by the sensor element 8 will be diminished by a factor corresponding to the dilution of the expiratory air. Therefore, another sensor element 7 is included in addition to the element 8, for measuring the concentration of a tracer gas, e.g. carbon dioxide (CO.sub.2) or water vapor. Since the tracer gas concentration is approximately constant when leaving the airways on expiration, it is possible to obtain a fair approximation of the degree of dilution of the air entering the sensor unit 5. Another option for a tracer signal besides CO.sub.2 and H.sub.2O is temperature. The temperature of expiratory air is almost the same as body temperature as it leaves the mouth or nose but is cooled will get closer to ambient upon mixing.

[0024] The sensor elements 7 and 8 constitute the receiver ends of a measurement cell for infrared (IR) transmission measurement. From an infrared emitter 6, preferably a blackbody radiating element, a beam of broadband infrared radiation is illuminating the cell, and eventually after multiple reflections it will reach the elements 7, and 8. Preferably, the emitter 6 is modulated at a frequency, e.g. 5 Hz, above the frequency band of typical signals. Each of the sensor elements 7 and 8 include thermopile detectors of infrared radiation with bandpass interference filters tuned to the absorption peak of the substance to be detected. The element 8 includes a filter with the pass band within the interval 9.1 . . . 9.9 μm for ethyl alcohol, and the element 7 the filter in the interval 4.2 . . . 4.3 μm in the case of CO.sub.2 as tracer gas. Water vapor, an alternative tracer gas, has strong absorption in the wavelength intervals 2.5 . . . 2.8 μm and 5.7 . . . 6.9 μm. Other combinations of gases and filter characteristics are possible. Acetone, acetaldehyde, methyl alcohol, carbon monoxide, methane, ethane, propane, pentane, hexane, heptane, octane, isoprene, ammonia, hydrogen sulfide, methyl mercaptan, ethyl acetate, dimethyl ether, diethyl ether, benzene, toluene, methyl ethyl ketone, and methyl isobutyl ketone are examples of volatile substances that may be of interest interest from a diagnostic or toxicological perspective.

[0025] The optical path from the IR emitter 6 to the detectors 7, and 8 may depend on the concentration range and the absorption coefficients of the actual substances. CO.sub.2 has strong absorption and high concentration in expiratory air which calls for a short optical path, 10-25 mm. For alcohol detection below the legal concentration limits, path lengths of more than 0.5 m may be necessary. By folding the optical path using multiple reflections, the length/width/height of the sensor unit 5 can still be kept smaller than 70/30/15 mm.

[0026] The sensor unit 5 responds almost instantaneously, i.e. within a fraction of a second, to concentration variations occurring at the inlet area 4. This is partly due to the small distance between the inlet area 4 and the sensor unit 5, typically 10-20 mm, its small inner volume, typically 20-60 ml, and the air volume flow, typically 100-200 ml/sec, generated by the fan 9. It is also due to the relatively fast modulation frequency of the infrared emitter. The signal information extracted from the sensor elements 7 and 8 is represented as the amplitude of the modulation frequency.

[0027] The signals from the sensor elements 7, 8 are brought to an analyzer 10, which preferably includes a general purpose digital microcontroller with capacity to execute signal algorithms, and also controlling the audiovisual unit 3, IR emitter 6, fan or pump 9. Signal conversion between different formats, including analog signals, can be managed by the microcontroller 10, which will also be capable of communicating with external units, e.g. an actuator unit for taking action or counteraction depending on the result of the breath test. Electric power for the system 1 can either be obtained from a battery or from an external power source. The system 1 can be designed as a stand-alone unit, or as an integrated part of other inventories, e.g. a vehicle compartment or entrance of building or workplace. Preferably, the inlet area 4 includes means for protection of the sensor unit 5, e.g. a lid which is closed when the system 1 is inactive.

[0028] In order to meet requirements on electromagnetic emission and immunity, the system according to the invention includes capacitive and inductive electronic elements for protective purposes. In addition, the elements 7 and 8 and their associated analog input stages are preferably equipped with differential preamplifiers in order to suppress the influence of common mode interference.

[0029] The system according to the invention is preferably confined in a box to be wall-mounted in such a way that the means for registration 2, audiovisual unit 3, and inlet area 4, are located on one side of the box and thereby accessible through a hole in the wall.

[0030] FIG. 2 shows a flow diagram of the system function according to the invention. The system is started or initiated either manually or automatically, by some external control signal. In the case of a vehicle, the start signal could be unlocking of the vehicle doors. The initiating phase preferably involves some self-testing functions of the system, to make sure that no functional errors have occurred since the previous test occasion. The initiating phase could also include preheating of sensitive components and stabilization of signals.

[0031] When the system is ready for test it will remain in a standby condition until the presence of a person within the predefined position is detected. As previously described, detection may or may not involve identification of the person, and could require two-way communication between the person and the system. After or during the presence detection step, the system will call for the person's attention by coordinated flashing light, distinctive and directional sound combined with specific symbol or icon representing the breath test.

[0032] An experienced person is then expected to direct expiratory air towards the sensor inlet area, whereas an inexperienced person may require a more or less detailed instruction on how to proceed. Example of instruction provided verbally or as a text message: “Take a deep breath, lean over, open your mouth wide and exhale gently.” Alternatively, instructions are provided by text, still or moving images, graphic symbols or other means. If the criteria for breath detection are not fulfilled after one round of instruction, repeated instructions may be delivered at increasing level of detail.

[0033] The criteria for breath detection preferably involve tracer gas detection as previously described. In the case of CO.sub.2 as tracer gas, a simple criterion is reaching a threshold CO.sub.2 concentration of e.g. 2500 ppm (parts per million), which corresponds to a dilution factor of 20 (alveolar CO.sub.2 concentration being approximately 5 vol %, or 50 000 ppm). Additional criteria could be related to the time derivative of the CO.sub.2 signal. The simultaneously measured alcohol concentration will in this case have to be multiplied with 20 in order to obtain an estimated breath alcohol concentration. The criteria for breath detection should also include correction for background CO.sub.2 concentration, which is typically 400-600 ppm in normal environments. A mathematical expression or algorithm will normally be adequate for defining the criteria, using settable parameters to adapt for variations between different conditions. Such an algorithm can be implemented for execution in real time using standard microcontrollers.

[0034] The level of dilution is a measure of the signal quality. High concentration (small dilution factor) provides high confidence of the determination, whereas the influence of interfering factors, such as other nearby persons, will increase with degree of dilution. Preferably, the result of the breath test is presented not only as a concentration but also in terms of an estimated error depending on the dilution factor.

[0035] Breath detection may in some applications override the presence detection as symbolized in FIG. 2 by the dotted line short-cutting both the ‘attention’ and ‘instruction’ sequences. Another way of expression is to include the tracer gas detection into the ‘means of registration’.

[0036] Determination of BrAC is performed by another algorithm based on the correlation between the signals from the sensor elements 7 and 8. When the sensor unit 5 is receiving expired air from a person, both sensor elements exhibit concentration peaks which occur almost simultaneously. An average BrAC value is obtained by multiplying a number of measured alcohol concentrations by their respective dilution factors. By averaging, the effect of noise and interference is reduced. A small time difference between the CO.sub.2 and the alcohol signals due to differences caused by the anatomic dead space or by the design of the sensor unit 5 is also possible to accommodate in the algorithm.

[0037] The completion and result of a breath test defined by fulfillment of the criteria for breath detection, is preferably communicated to the person, e.g. using the audiovisual unit 3.

[0038] In the flow diagram of FIG. 2, the further steps taken after termination of the actual breath test are not included, since they may be highly depending on the actual application of the breath test. Such steps may involve rule-based decision for controlling action or counteraction based on the determination, e.g. enable/disable functions of a vehicle or locking/unlocking of door.

[0039] FIG. 3 shows time sequences of typical breath tests performed with the system according to the invention for (a) and experienced person, and (b) an inexperienced person. From top to bottom the signals represented are: ‘P’ presence, ‘C’ communication, ‘T’ tracer gas, ‘A’ alcohol in both diagrams 3 (a) and 3 (b).

[0040] In the time sequence of FIG. 3 (a) a person is detected within the first half second, and is almost immediately followed by the ‘attention’ communication to the experienced test person, who responds after another half a second by distinctive peaks representing both the tracer substance and alcohol. After two seconds, the breath test is completed.

[0041] The time sequence of FIG. 3 (b) follows a somewhat different pattern. The inexperienced test person does not immediately respond, but requires a short instruction before supplying an approved breath. The entire sequence is completed after 15 seconds.