CAP FOR OPTICAL ILLUMINATION ON A CONTAINER
20240395382 ยท 2024-11-28
Inventors
Cpc classification
A61J7/04
HUMAN NECESSITIES
B65D51/248
PERFORMING OPERATIONS; TRANSPORTING
G09F7/08
PHYSICS
International classification
F21K9/235
MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
Abstract
A cap for optical illumination on a container can include a top portion and a base portion having a curved outer surface. The base portion can have a channel formed on at least a part of said curved outer surface. The cap can include a light-emitting diode (LED) electronically connected to circuitry within the cap. The cap can include a light pipe in optical communication with the LED configured to direct light from the LED through the portion of the top portion defined by the light pipe. The cap can include a sensor configured to detect changes in ambient illumination and the LED can turn off when sensor detects the ambient illumination is low.
Claims
1. A cap for optical illumination on a container, the cap comprising: a base portion being connectable to a container; a top portion positioned above the base portion and coupled to the base portion; a light-emitting diode (LED) electronically connected to circuitry disposed within the cap; and a light pipe in optical communication with the LED, a portion of the light pipe forming a part of the top portion and being capable of directing light from the LED through the part of the top portion away from the container.
2. The cap of claim 1 further comprising an RF transmitter disposed within the base portion and electronically coupled with the circuity, wherein the RF transmitter is configured to transmit a signal including data relating to a history of dosing event.
3. The cap of claim 1 further comprising an RF receiver disposed within the base portion and electronically coupled with said circuity, wherein the RF receiver is configured to receive a signal including data relating to one or more of a dosing regimen or display information.
4. The cap of claim 1 further comprising a speaker disposed within the base portion and electronically coupled with the circuitry.
5. The cap of claim 1 further comprising at least one switch electronically coupled with the circuitry.
6. The cap of claim 5 wherein the at least one switch detects removal of the cap from a container.
7. The cap of claim 6 further comprising a button mechanically coupled with the at least one switch and configured to actuate the switch in response to a user depressing the button to manually signal an event via the circuitry.
8. The cap of claim 7 wherein the event comprises a refill request.
9. The cap of claim 1, the cap configured to removably secure to one or more of a bottle, a pill box, a salve tube, a syringe, an inhaler, a pump dispenser, or a drop dispenser.
10. The cap of claim 1 wherein the top portion further includes a pair of opposed surfaces extending toward each other from opposed regions of the base portion, wherein each of the opposed surfaces of the top portion defines an externally concave configuration.
11. The cap of claim 10 wherein the top portion further includes a top surface positioned between the pair of opposed surfaces.
12. The cap of claim 1 wherein the LED comprises a multi-color LED.
13. The cap of claim 1 further comprising an electronic display received in a channel formed on at least a part of a curved outer surface of the base portion, said channel electronically connected to the circuitry disposed within the cap.
14. The cap of claim 13 wherein the electronic display extends around at least part of a perimeter of the base portion.
15. The cap of claim 13, the electronic display comprising: a flexible electronic e-ink display fitting in the channel of the base portion and forming a curved display surface that follows a curvature of the base portion, wherein the e-ink display comprises a membrane of sandwiched charged rotatable microspheres.
16. The cap of claim 13 further comprising a second display distinct from the electronic display, the second display coupled with the circuitry.
17. The cap of claim 13 further comprising a transparent cover covering the electronic display, wherein the transparent cover is tinted with a color.
18. The cap of claim 13 wherein the electronic display is about 0.375 m thick at its thickest part.
19. The cap of claim 13 wherein the electronic display comprises flexible driver wires configured to couple with a connector of the circuitry.
20. The cap of claim 13 wherein the circuitry is operative to provide visual feedback via the electronic display according to a medication regime.
21. The cap of claim 1 further comprising: at least one optical sensor electronically connected to the circuitry within the cap, the at least one optical sensor configured to detect changes in ambient illumination, wherein the LED is configured to turn off when the at least one optical sensor detects the ambient illumination is low.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
[0016] The following description, given with respect to the attached drawings, may be better understood with reference to the non-limiting examples of the drawings, wherein:
[0017]
[0018]
[0019]
[0020]
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[0022]
[0023]
[0024]
[0025]
[0026]
[0027]
[0028]
[0029]
[0030]
THE PRESENTLY PREFERRED EXEMPLARY EMBODIMENTS
Overview
[0031] Well-established behavioral medicine research shows that non-compliance with a medication regimen is fundamentally a behavioral psychology problem. The inventors have realized that timely intervention(s) by machine or human may influence the patient and should increase medication adherence rates.
[0032] There are several reasons why patients may not comply with their medication regimens. No one reason or set of reasons may apply to all people. People are motivated in different ways and by different things, and it is an unknown and possibly unique mix of factors that will motivate any particular individual to comply. The inventors have realized that any system for creating or supporting medication compliance will preferably be multi-faceted and be able to learn and adapt to each patient during their course of treatment.
[0033] Commonly acknowledged reasons for non-compliance include the following: [0034] Lack of doctor-patient accountability. [0035] Medication is too expensive. [0036] Lack of social support. [0037] Patient's complain or perceive difficulty obtaining refills. [0038] Some patients think that they do not need the medication. [0039] Some patients do not know how to use the medication. [0040] Patients forget to take their medication. [0041] Patients complain of unpleasant side effects
[0042] The inventors have realized that a solution to the lack of compliance problem should deal with some or all of these factors.
System Architecture
[0043]
[0044] A compliance framework can be considered in three logical parts, namely the patients' homes (each a so-called local end), a back end, and a part corresponding to external entities that may be involved in the compliance system. The term patient's home is used herein to refer to the place (or places) at which a patient is expected to take his medication. It may include, e.g., the patient's home and/or place of work. The patient's home is sometimes referred to herein as the local end.
[0045] At a patient's home (or wherever they are supposed to take their medication), the patient is provided with a local system that includes a system manager 102, an optional feedback indicator 104 and a connector 106. The connector 106 allows the local end to connect with the rest of the system (e.g., the back end), and may be a modem, a network connection and the like. Some or all of these components may be integrated into a single device. For example, the system manager 102, a feedback indicator 104, and the connector 106 may be co-located and/or provided in a single device. Alternatively, e.g., the system manager 102 and connector may be formed in a single device. If there is more than one feedback indicator, the system manager may be incorporated into one of them. In a presently preferred embodiment, the system manager 102, feedback indicator 104, and connector 106 are integrated in a single device which includes a night light indicator.
[0046] The patient's medication is provided in a container 108 with a cap 110. The container 108 may be a regular container or may be specifically adapted to operate with the cap 110. The container/cap combination may be in the form of pill cap, a multi-compartment pillbox, a salve-tube cap, a syringe, an inhaler, a pump dispenser, a drop dispenser and the like. Those of skill in the art will understand, upon reading this description, that the container/cap combination can be used with any medication delivery system and with any type of medication, regardless of its form or dosage. The cap 110 may be fully or partially removable or fully or partially openable, or it may be an integral part of the container through which medication is dispensed. In presently preferred implementations using the cap with the electronic embedded curved display described herein, the container is a regular threaded pill bottle.
[0047] At least one sensor 112 is embedded into the medication container 108 and/or the cap 110. The sensor 112 is triggered whenever the container is opened and closed. The sensor may be a pressure sensor, a piezoelectronic sensor, a light sensor, a motion sensor or the like. If more than one sensor is used, the sensors need not all be of the same kind. The function of the sensor(s) is to detect that the medication container has been opened (and then closed). Any sensor(s) (alone or in combination) that achieve this function are acceptable.
[0048] Those of skill in the art will realize, upon reading this description, that the container/cap combination may take any form, as long as the system can detect when medication was likely or possibly dispensed.
[0049] Although only one medication container 108 is shown in detail in
[0050] A particular system may be open or closed. A closed system will only allow specific and dedicated caps to upload data through the network gateway. (The inventors characterize a closed system as a family of devices in which family members can talk to other family members.) An open system allows all caps to upload their data through the network gateway. (In an open system any member of one family can talk to members of another family.)
[0051] Thus, a particular patient may have more than one container (as shown in
[0052] The system assumes that if the medicine container has been opened and then closed, that the medication was actually taken and that the dosage was correct. Preferably the number of pills has to be accounted for upon setup. This known number at the start is decremented by the dosage amount when the cap is opened, and is used to determine whether to initiate a refill.
[0053] A local end may also include one or more peripheral sensors 107 to measure and provide data such as the patient's weight, blood pressure (BP), pulse, etc. Peripheral measurements can be provided automatically to the system manager 102 and, in some cases, may be requested by the system manager.
[0054] The various containers, sensors and feedback indicators may communicate with the system manager 102 in any known way. The presently preferred implementation uses radio frequencies (ISM band) similar to that used in domestic garage door openers or key fob key-less entry systems. Other protocols such as Bluetooth, ZigBee, Z-wave, 802.11, etc. may be used.
[0055] The system manager 102 receives information from and about the sensors in its jurisdictionthe patient's home (in a closed system the system manager will only interact with known sensors). The system manager 102 also communicates with the back end, e.g., via connector 106 using, e.g., a network or a phone system. In some embodiments, the connector 106 is a dedicated telephone dial-up, Ethernet or cellular modem called a network gateway. A network agnostic model may also be used where the network gateway has a plurality of embedded modems and, in the limiting case, the one with the lowest cost of connection, strongest signal or present availability (for instance) defines the connection used. The choice of connection is managed by the central processor or dedicated processor that is in receipt of decision making information from the network(s).
[0056] A network gateway is a device that connects the system manager 102 to an external network via POTS (Plain Old Telephone Service) line modem, cellular, pager, 802.11 connections, or the like. In the POTS line modem version, the connector device may be embedded into a so-called dongle. In addition to the network connectivity, the dongle may communicate with the system manager over wireless, radio frequency communications.
[0057] In a presently preferred embodiment, the connector 106 is a cellular modem that connects to the back end via a cellular telephone network.
[0058] The suite of devices described above communicates locally (in the home) and asynchronously from the virtual backend system components. Schematically these are local devices that communicate with the backend.
Backend
[0059] The backend is a data service platform that manages individual patients' data. The structure and operation of the backend are described in detail in co-pending U.S. application Ser. No. 12/352,647, filed Jan. 13, 2009, and titled Medication Dispenser with Automatic Refill, (Atty. Docket No. 2694-0005), which has been incorporated herein by reference for all purposes.
Pill Cap
[0060]
[0061] With reference to the diagram in
[0062] A one-way pill cap only contains an RF transmitter but no receiver. It broadcasts a signal whenever it is opened and then closed within some period of time. Optionally this transmit signal may also be bundled with a payload of data which includes, battery level and a history of last dosing events (e.g., valid close times, where valid is defined to be the time between open and close is short and known) times, unique identification, etc.
[0063] A two-way pill cap 400, e.g., as depicted in
[0064] Those skilled in the art will realize, upon reading this description, that different and/or other data may be provided to a one-way cap and to and from a two-way cap.
[0065]
[0066] With reference to
[0067] The bottle cap 500 includes a light pipe 512 (not shown in
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[0069]
[0070] The board 510 also includes RF (radio frequency) transmitter/receiver 404, data store (e.g., EEPROM memory) 406, a clock 413, refill button/switch 412, computational resource (computer) 414, a reset control 420, and appropriate circuitry which ties these components together to enable the functional behavior to take place.
[0071]
[0072]
[0073] Preferably the display 502 is a flexible display that uses ultra-low power and is easily read under any lighting condition including direct sunlight. Also, preferably the display 502 should look the same from various different viewing angles and should not distort when touched or flexed.
[0074] The display is preferably monochrome and uses a fixed set of glyphs, a so-called, segmented display, as is common in the realm of low cost liquid crystal displays. If the number of display segments is very dense, a so called dot-matrix display may be created. In this configuration, the displayed content could become a 2D bar-code readable display enabling it to also function as a machine-readable information display.
[0075] In a presently preferred implementation the display 502 is made by E Ink Corporation of Cambridge, Mass. The display 502 is flexible and so curves with the curve of the main body 508. In presently preferred embodiments, the display is about 0.3750.020 m thick at its thickest part.
[0076] The E Ink display features a membrane of sandwiched charged microspheres that may be rotated to indicate information by changing the charge in a fluid that surrounds the microspheres. Properties of this display that make it desirable for this invention are its extreme low power requirements, mechanical stability, wide viewing angle and sunlight readability. In addition, this invention benefits from this display technology being ultra thin, lightweight and flexible.
[0077] To control the display an array of driver wires (538 in
[0078] To maintain the curvature of the cap, the display preferably fits into a receiver channel in the base 508. To make the display appear as if it is on the exterior surface of the cap and not protruding from that surface, a shallow bezel may receive the display so that its top surface shares a common radius with the cylindrical caps exterior. Accordingly, an appropriate indent is preferably formed in the main body 508 to hold the display in place against the body.
[0079] To protect the display from damage due to handling, etc., a optionally transparent, wrapper (clear portion 506) covers the display. This wrapper may be selectively tinted as a pneumonic device for the cap owner to recognize which medicine is in the container using the cap. E.g., the transparent wrapper may be tinted a color (e.g., such as red) to help the user identify the medication. Accordingly, the clear portion 506 fits over the display and main body and keeps the display in place and protects it.
[0080] The presently preferred connector 522 is a 45-contact connector made by FCI (part number 62684-451100ALF).
[0081] While the display is shown in the drawings as going around only a part of the main body (and thus the cap), those of skill in the art will appreciate and understand, upon reading this description, that the display can have different dimensions in length and height, and that the display can cover a greater or smaller portion of the cap. In addition, while the cap is shown with only one display, those of skill in the art will appreciate and understand, upon reading this description, that more than one display can be used, though each display could require its own connector on the board 510.
[0082]
TABLE-US-00001 TABLE 1 Pin Segment description 1 top plane 2 Field 3 One 4 Bottom left 5 Battery 6 Top left 7 Top 8 Middle 9 Bottom 10 Top right 11 Bottom right 12 Antenna signal 13 AM 14 PM 15 M bottom middle 16 M bottom outside 17 M top outside 18 M top middle 19 T bottom middle 20 T bottom outside 21 T top outside 22 T top middle 23 W bottom middle 24 W bottom outside 25 W top outside 26 W top middle 27 T Bottom middle 28 T Bottom outside 29 T top outside 30 T top middle 31 F bottom middle 32 F bottom outside 33 F top outside 34 F top middle 35 S bottom middle 36 S bottom outside 37 S top outside 38 S top middle 39 S Bottom middle 40 S bottom outside 41 S top outside 42 S top middle Pins 43, 44, 45 have no connection
[0083] The mapping of the pins shown in Table 1 above is implementation dependent. Thus, while a specific wiring to the indicia/components in the display is shown in the drawing, those of skill in the art will know and understand, upon reading this description, that different and/or other wiring may be used, depending on the display.
[0084]
[0085]
[0086] Switch 528 (corresponding to 412 in
[0087]
[0088] The main body main include an indented circular portion 509. This portion may be color coded to provide additional information to the patient.
[0089] The patient's medication is provided in a container with a cap. The container may be a regular container or may be specifically adapted to operate with the cap. Those of skill in the art will understand, upon reading this description, that the container/cap combination can be used with any medication delivery system and with any type of medication, regardless of its form or dosage. The cap may be fully or partially removable or fully or partially openable, or it may be an integral part of the container through which medication is dispensed.
[0090] Those of skill in the art will realize, upon reading this description, that the container/cap combination may take any form, as long as the system can detect when medication was likely or possibly dispensed.
[0091] In a preferred embodiment the pill cap includes a light sensor that can detect changes in ambient illumination. This is part of a further battery saving scheme that enables the illuminator to turn off if the container is stored in a dark place. Patients often store their medication in a closed cabinet or drawer (much medication should be stored in a dark place) and there is no reason to deplete battery illuminating the feedback signal if no one can see it. In this scenario the pill cap immediately gives visual indication that it is dose time (its me (as opposed to the other caps for which it is not time to dose now)) if dose time has occurred and the ambient light sensor has indicated a change (suggesting it is in view of patient). The ambient light sensor could be replaced with or supplemented with a motion sensor.
[0092] In some embodiments, the sensor also detects that the correct medication dose was actually removed from the container.
[0093] The display 502 embedded in the cap can provide textual and other visual feedback to the patient. Data on display 502 may instruct the patient which dose (afternoon/morning, etc.), which pill (shape, color, size) needs to be taken.
[0094] The cap includes local data memory and permanent memory. The device preferably includes a store and forward architecture to ensure data collected on it has a physical location in which to reside if an upload network connection is not possible for some period of time.
[0095] A smart cap version provides interoperable mounting rings or bases to the cap. If needed, coupling rings are provided to enable one type of smart cap to mount to any of a variety of commercially available bottles of near similar opening diameter. This avoids having to develop custom caps for each bottle and enables patients to take this platform and use it for medications provided in vials sold by disparate retail pharmacies.
[0096] Thus is described a bottle cap having an embedded electronic display that curves around the cap's exterior. The cap is operable in service of promoting medication adherence with a novel feedback loop, e.g., as described in the related patent applications which have been incorporated herein by reference. A cap preferably includes at least the following functional components: [0097] battery, [0098] processor, [0099] open/close switch, [0100] some mechanism for keeping time; and [0101] the curved electronic display.
[0102] The display may provide useful information, e.g., an indication of whether the cap has been opened and may optionally indicate a schedule of past open events or indicate future events. The display may also display other information such as, e.g., instructions, medicine name, battery level, time, network connectivity strength (if RF connectivity is also embedded in the cap), patient name, availability of rewards, financial incentives, social network status, who the data is shared with or other such medically relevant information.
[0103] In a preferred embodiment, the cap also has network connectivity via standard means (local RF or intermittently via physical connector). In this configuration, among other messages, e.g., the display may indicate environmental conditions such as pollen forecast for allergy related medication, biometrics such as blood pressure for hypertension patients or whether a refill is pending pickup or has been ordered.
[0104] As used herein, the term medication refers to any kind of medicine, prescription or otherwise. Further, the term medication includes medicine in any form, including, without limitation pills, salves, creams, powders, ointments, capsules, injectable medications, drops, vitamins and suppositories. The scope of this invention is not limited by the type, form or dosage of the medication.
[0105] Although aspects of this invention have been described with reference to a particular system, the present invention operates on any computer system and can be implemented in software, hardware or any combination thereof. When implemented fully or partially in software, the invention can reside, permanently or temporarily, on any memory or storage medium, including but not limited to a RAM, a ROM, a disk, an ASIC, a PROM and the like.
[0106] While certain configurations of structures have been illustrated for the purposes of presenting the basic structures of the present invention, one of ordinary skill in the art will appreciate that other variations are possible which would still fall within the scope of the appended claims. While the invention has been described in connection with what is presently considered to be the most practical and preferred embodiment, it is to be understood that the invention is not to be limited to the disclosed embodiment, but on the contrary, is intended to cover various modifications and equivalent arrangements included within the spirit and scope of the appended claims.