BISMUTH OXIDE BASED AMMONIA SENSOR

Abstract

A bismuth oxide material with a hierarchical structure in gas detection used for detecting the content of low-concentration ammonia in an environment. The bismuth oxide material with the hierarchical structure integrally presents a microsphere shape. The diameter of the microsphere is 1-3 μm. The bismuth oxide material is formed by self-assembling lamellar structure units with the thickness of 10-80 nm. The bismuth oxide material is made into a gas sensor with high sensitivity and selectivity to ammonia gas at room temperature, which is suitable for detecting trace harmful gas in the environment. The gas sensor made of bismuth oxide does not need to be heated when in use, so that the heating step of the conventional gas sensor is omitted, and the gas sensor can be directly placed in a normal-temperature environment for operation. The method is simple, easy to operate, high in efficiency and wide in application prospect.

Claims

1. A method of detecting ammonia in a user's breath, wherein the ammonia is detected by porous bismuth oxide endowed renewable seaweed fabric.

2. The method of claim 1, wherein the porous bismuth oxide material is prepared by a one-pot hydrothermal method; the method comprising the steps of: a) dissolving an amount of bismuth nitrate in a mixture of ethanol and ethylene glycol, and kept stirring at room temperature; b) transferring the above mixture into a Teflon®-lined stainless-steel autoclave; c) reacting the mixture at 120-160° C. for 2-16 hours; d) collecting the precipitates by centrifugation; e) washing the product with absolute ethanol and deionized water; and f) air-drying the product at 60° C. in an oven for more than 8 h.

3. The method of claim 1, wherein the bismuth oxide material possesses microsphere morphology with diameter of 4-6 μm.

4. The method of claim 3 wherein the microspheres are assembled by multiple interlaced two-dimensional (2D) nanosheets with thickness of 10-50 nm to produce an aggregate.

5. The method of claim 4 wherein the aggregate structure has the appearance of an aggregate of micro-flowers.

6. The method according to claim 1, wherein the renewable seaweed fabrics are fabricated from alginate fibers by wet-spinning and papermaking processes.

7. The method according to claim 1, wherein the thermally treated semiconducting bismuth oxide is combined with renewable seaweed fabrics by a spray technology; preferably wherein the bismuth oxide and renewable seaweed fabric comprise a composite layer having a thickness of about 100-250 μm.

8. A gas sensor for detecting ammonia in the environment, wherein the gas sensor comprises a porous bismuth oxide endowed renewable seaweed fabric.

9. The gas sensor according to claim 8, wherein the gas sensor comprises a flexible gas sensor.

10. The gas sensor according to claim 9, wherein the flexible gas sensor is flame retardant and reproducible at either flat or bent states.

11. The gas sensor according to claim 8, for use in the detection of ammonia in patients having a Helicobacter pylori infection.

12. The gas sensor according to claim 8, wherein the gas sensor is provided in a wearable medical device.

13. A gas sensor according to claim 12, wherein the wearable medical device is configured to receive, analyze and output physiological health data.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0005] FIG. 1 is a SEM image of the Bi.sub.2O.sub.3 material with hierarchical structure according to an embodiment of the invention.

[0006] FIG. 2 is a SEM image of the renewable seaweed fabric according to an embodiment of the invention.

[0007] FIG. 3 is a SEM image of the Bi.sub.2O.sub.3 endow seaweed fabric according to an embodiment of the invention.

[0008] FIG. 4 is the limiting oxygen index (LOI) index refers to the Bi.sub.2O.sub.3 endow seaweed fabric according to an embodiment of the invention, as compared with the traditional A4 paper and seaweed fabric (SA).

[0009] FIG. 5 is the XRD pattern of the annealed Bi.sub.2O.sub.3 material according to an embodiment of the invention.

[0010] FIG. 6 is a response-recovery curve of a fabricated gas sensor to 20 ppm NH.sub.3 according to an embodiment of the invention.

[0011] FIG. 7 is the response of a fabricated gas sensor to 20 ppm different gases according to an embodiment of the invention.

[0012] FIG. 8 is the response of a fabricated gas sensor measured under different bending angles according to an embodiment of the invention.

[0013] FIG. 9 is the response of a fabricated gas sensor measured under different relative humidity according to an embodiment of the invention.

[0014] FIG. 10 is the relationships between the sensor response and NH.sub.3 concentration according to an embodiment of the invention.

[0015] FIG. 11 is the transient curves of a flexible gas sensor upon exposure to a healthy breath and illness breath of a patient with Helicobacter pylori infection according to an embodiment of the invention.

[0016] FIG. 12 is the overall structure of a flexible gas sensor according to an embodiment of the invention.

DETAILED DESCRIPTION

[0017] The invention adopts a simple one-step hydrothermal method to prepare the hierarchical bismuth oxide microspheres and a simple spray technology to prepare bismuth oxide endow renewable seaweed fabrics. These three-dimensional (3D) hierarchical microspheres with diameters of 4-6 μm are assembled from two-dimensional (2D) nanosheets with thickness of 10 to 50 nm, ensuring a higher contacting area for the gas adsorption, which could allow the application of devices with excellent performance. The obtained bismuth oxide endow renewable seaweed fabrics (Bi.sub.2O.sub.3/SA) displays excellent flexibility, flame retardancy and can withstand deformation (e.g. bending), providing possibility for the realization of flexible and wearable sensor. The flexible gas sensor can work at room temperature, and exhibits high response (1300), ultrashort response/recovery time (<25 s/10 s), small detection limit (100 ppb), and high selectivity to ammonia. Additionally, the gas sensor displays excellent anti-interference ability, long-term stability and reproducibility. Also, the gas sensor shows excellent response to exhalation in Helicobacter pylori infected patients. The above results provide us with the opportunity that a room-temperature operated gas-sensitive oxide semiconductor can be integrated with flexible and renewable seaweed substrate to achieve a smart wearable electronic device for real-time environment monitoring and medical diagnosis.

[0018] FIG. 1 shows that the as-synthesized product is a compact aggregate of flower-shape microspheres with diameters of 4-6 μm, and these nanoflowers are actually assembled by many interlaced 2D nanosheets with the thickness in the range of 10-50 nm. Mostly, uniform thickness of nanosheets gather with each other in the spherical way, forming a porosity surface and the hollow interiors. FIG. 2 shows that the renewable seaweed fabric (SA) interweaves with each other, increasing the surface-to-volume ratio. After spraying, numerous of bismuth oxide microspheres are on the surface and interweave of SA fibers (FIG. 3), and the thickness of the Bi.sub.2O.sub.3/SA composite layer is about 200 μm. As shown in FIG. 4, the LOI index refers to the minimum concentration of oxygen in a mixture of oxygen and nitrogen which will be used to determine the flammability of the samples. The LOI levels of SA and Bi.sub.2O.sub.3/SA are obviously higher than that of traditional A4 paper, revealing the good flammability.

[0019] X-ray diffraction (XRD) was used to characterize the crystal structure of the prepared Bi.sub.2O.sub.3, as shown in FIG. 5. Each characteristic peak is consistent with the standard card PDF #71-2274, and the main crystal plane spacing d value: 3.4564, 3.3112, 3.2532, 3.1830, 2.7097 and 2.6918 correspond to the crystal planes of (002), (111), (012), (202), (121) and (200) of monocline Bi.sub.2O.sub.3 respectively. It can be observed that there is no excess impurity peak in the Bi.sub.2O.sub.3 sample.

[0020] FIG. 6 shows that the response and recovery time of the gas sensor to 20 ppm NH.sub.3 at room temperature. When the Bi.sub.2O.sub.3 material is exposed to atmosphere, the oxygen molecules are absorbed onto the surface, they capture these free electrons and become O.sup.2− irons at room temperature, forming the electron-depletion depletion region and causing high resistance of the Bi.sub.2O.sub.3 sensor in air. Upon adsorption of NH.sub.3, which is a reductive gas, more electrons transform the substrate, resulting in a decrease in resistance. The whole process takes only 20 s. The large surface area to volume ratio and high porosity of the hierarchical structures can generate abundant channels for NH.sub.3 mass transfer and provide abundant active sites, which greatly reduces the gas desorption time (7 s).

[0021] The selectivity of the gas sensor is a significant parameter for gas sensors, and we compare the response of the gas sensor toward various gases with a concentration of 20 ppm. As shown in FIG. 7, the sensor exhibits the highest detection response to 20 ppm NH.sub.3 (about 1300), and negligible response when exposed to methanol, isopropanol, methanol, ethanol, acetone and triethylamine, indicating weak interference for NH.sub.3 detection. The prepared Bi.sub.2O.sub.3 material show high response and selectivity towards NH.sub.3.

[0022] In addition to normal flat state, the Bi.sub.2O.sub.3/SA sensor is flexible and can be bend at different angles without losing its gas-sensitive properties (FIG. 8). The response of the gas sensor changes in range of 4%-9%. Meanwhile, inconspicuous changes in response time (1-5 s) and recovery time (3-8 s) can also be nearly ignored, confirming the excellent stability of the sensor.

[0023] To explore the effect of relative humidity to the gas sensor, the sensor response were recorded at various humidity conditions (20% RH, 40% RH, 60% RH and 90% RH) at room temperature, as shown in FIG. 9. Apparently, there is a tolerable decrease of the response with the increase of respective RH value of 20-90% RH, because of the interference of water molecules with the surface adsorbed target gas of gas sensor. However, a linear-relationship with R-square of 0.99308 between the response and relative humidity is observed, indicating that the response can be sufficiently predictable in the whole humidity.

[0024] As shown in FIG. 10, the response of the gas sensor has a linear relationship with triethylamine concentration, which was consistent with the law of gradually increasing response. According to the least-squares method of fitting in the linear regime, the theoretical low detection limit (D.sub.L) of gas sensor is the value of gas concentration when sensor response is three times greater than the standard deviation of noise signal (rms.sub.noise). Thus, the theoretical low detection limit of the gas sensor is calculated to be about 100 ppb.

[0025] To determine the application potential of using the gas sensor for simple medical diagnosis, the gas sensitivity of synthesized illness gas containing trace NH.sub.3 respiration is tested. The exhaled breath of healthy people is collected with a 500 mL gas sample bag and injected into the vacuum chamber. For a health breath, the obtained gas has little effect on the sensor resistance (FIG. 11). We then injected 50 ppm of NH3 into a gas sample bag and mixed it with normal exhalation gas to form synthesized illness gas, resting for 1 hour to simulate the exhaled air of Helicobacter pylori infected patients. We found that the sensor resistance decreased obviously after synthesized illness gas injection, indicating high potential for feasibility of the flexible gas sensor as new sensing platforms.

[0026] FIG. 12 shows the overall structure of a flexible gas sensor, containing layers of substrate 1, electrode 2, sensitive material 3 and packaging material 4.

Embodiment 1

[0027] The pure Bi.sub.2O.sub.3 nanosphere is synthesized using a facile one-pot hydrothermal method. In a typical process, 0.97 g of Bi (NO.sub.3).sub.3 is dissolved in the mixture of 34 mL of ethanol and 17 mL of ethylene glycol and kept stirring at room temperature. Then the above mixture is transferred into a 50 ml Teflon-lined stainless-steel autoclave and reacted at 160° C. for 5 h. The white precipitates are collected by centrifugation and washed with absolute alcohol for several cycles, which are air-dried at 60° C. more than 8 h in an oven.

[0028] The crystallographic structural and morphology were investigated by X-ray diffraction, (XRD, DX2700) at 40 K and scanning electron microscope (SEM, Quanta 250 FEG) with an energy dispersive spectrometry (EDS) spectrometer. The as-synthesized product is a compact aggregate of flower-shape microspheres with diameters of 4-6 μm, and these nanoflowers are actually assembled by many interlaced 2D nanosheets with the thickness in the range of 10-50 nm. Each characteristic peak is consistent with the standard card PDF #71-2274, and the main crystal plane is in accordance with that of monocline Bi.sub.2O.sub.3.

Embodiment 2

[0029] A transparent solution was obtained by dissolving 0.5 g of bismuth nitrate pentahydrate (Bi(NO.sub.3).sub.3.5H.sub.2O) in 10 mL of ethylene glycol. Before 60 min of stirring at room temperature, 20 mL of ethanol were added into the above solution. Then the above mixture is transferred into a 50 ml Teflon-lined stainless-steel autoclave and reacted at 160° C. for 8 h. The white precipitates are collected by centrifugation and air-dried at 60° C. more than 24 h in an oven.

Embodiment 3

[0030] The seaweed fibers (SA) with length of 1-2 cm were mixed with deionized water, which was then transferred to a standard fiber dissociator and stirred at 1000 rpm for 20 minutes to ensure that the fibers were evenly dispersed in deionized water. Then, the uniform slurry was quickly transferred to a paper-making apparatus to make SA paper with thickness of 0.4 mm.

[0031] A uniform paste was obtained by thoroughly mixing the Bi.sub.2O.sub.3 samples with terpineol in an agate mortar, followed by spraying or coating on the SA papers. The above process is repeated several times to form a continuous thin coating on the SA surface. Then, zeolite film was coated on the sensing layer. Finally, the gas sensor element was dried overnight in an oven at 60° C. to improve stability.

[0032] The resistance of the sensor in air (R.sub.0) or target gas (R.sub.g) was tested in a heated vacuum chamber using a source measurement unit (Keithley 2612) with a DC bias voltage of 3 V and a homemade computer control system. The gas response of the sensor in this research was deduced as S=R.sub.0/R.sub.g (for reducing gases). The response time is defined as the time taken from R.sub.0 to R.sub.0−90%×(R.sub.0−R.sub.g) after injecting the target gas. The recovery time is defined as the time taken from R.sub.g to R.sub.g+90%×(R.sub.0−R.sub.g) after removing the gas.