Rapid individualized whole blood chip for antibiotic, drug, and food allergies

Abstract

The present invention describes a whole blood assay chip that enables separation of the cellular compartment from surrounding plasma, facilitating multiplexed measurement of otherwise difficult to detect soluble factors produced upon cellular stimulation. The invention is a microfluidic chip with an incubation chamber comprising an inlet, an outlet, and a fluidic barrier. Using this platform, the cellular compartment can be stimulated with various substances and levels of immunologic biomarkers could be measured. Through a proprietary immunologic algorithm described herein, this would allow for the diagnosis of an allergic response to foods, antibiotics, and/or other drugs. Additional applications of the invention besides allergy testing could include pregnancy testing, blood type, and medical applications requiring whole blood cellular stimulation readouts.

Claims

1. A microfluidic chip comprising: (a) an incubation chamber comprising an incubation inlet, an incubation outlet connected to a wash inlet, and a vertical fluidic barrier, wherein said fluidic barrier blocks the diffusion of particles in a solution of 0.1-20 microns in size; (b) a wash chamber comprising the wash inlet connected to the incubation outlet and a wash outlet connected to a readout inlet; and (c) a readout chamber comprising the readout inlet, a readout channel, and a readout outlet connected to the wash outlet and a readout outlet connected to a readout channel, wherein said readout channel comprises a series of sequentially ordered seats having a concave shape with an opening and a separation between the base of the seats, and wherein said readout chamber is configured to allow for a dual flow of the solution through the readout chamber, wherein said dual flow comprises: an unblocked main flow of the solution from the readout inlet to the readout outlet; and a shunt flow of the solution through the opening and separation at the base of the seats, and wherein the shunt flow of the solution through the readout chamber exhibits a hydrodynamic resistance ratio between the hydrodynamic resistance of the shunt flow direction through the first empty seat (R1) and the hydrodynamic resistance of the shunt flow direction through the next empty seat (R2) is from 1 to 3, wherein R1 is smaller than R2, wherein the hydrodynamic resistance is calculated using the solution for Poiseuille flow in a rectangular channel.

2. The microfluidic chip of claim 1, wherein: a) the solution is selected from a biological solution, a wash solution, a nutrient solution, and/or a solution of beads; b) the biological solution of a) is a blood sample, a serum sample, a plasma sample, a urine sample, a fecal sample, a saliva sample, a cerebrospinal fluid (CSF) sample, a bone marrow aspirate sample, and/or a vitreous sample; c) the particles in the solution are processed to detect antigen, detect antibody, capture DNA, capture RNA, capture any protein of interest, and/or capture any particles of interest in the target solution; d) the fluidic barrier blocks the diffusion of particles of a size selected from: 0.5 to 20 microns; e) the fluidic barrier is a micro-pillar, a porous wall, a porous membrane, a hydrogel, micro/nano-grid, or a PVDF-PZT composite; and/or f) the incubation chamber further comprises an incubation channel.

3. The microfluidic chip of claim 2, wherein the incubation channel further comprises: a) an outer channel separated from a center channel by the fluidic barrier; b) the center channel of a) positioned in between at least two outer channels; c) the center channel of a) or b) is surrounded by outer channels; d) the incubation channel is a concentric channel; e) a width of the incubation channel is between 1-500 microns in size; and/or f) a height of the incubation channel is between 1-500 microns in size.

4. The microfluidic chip of claim 1, wherein the incubation chamber comprises multiple incubation channels.

5. The microfluidic chip of claim 4, wherein the multiple incubation channels further comprise: a) at least 3 channels; b) at least two incubation channels connected to one another; c) all of the incubation channels are connected to one another; d) multiple incubation inlets and/or incubation outlets; e) the addition of multiple solutions thru the multiple incubation inlets of d); f) the addition of different solutions in e); g) incubation channels positioned radially, semi-radially, or parallel to one another; h) incubation channels connected to one another which process particles in the solution differently; and/or i) at least two of the incubation channels comprise fluidic barriers that block the diffusion of different sized particles.

6. The microfluidic chip of claim 5, wherein the fluidic barrier is a porous membrane, porous wall, hydrogel, micro/nano-grid, or PVDF-PZT composite.

7. The microfluidic chip of claim 1, wherein: a) the seats in the readout chamber are evenly distributed; b) the readout chamber comprises multiple rows of sequentially ordered seats; c) the multiple rows of b) are separated by a flow guide structure; and/or d) the readout chamber comprises between 2-400 seats.

8. The microfluidic chip of claim 1, wherein the incubation chamber further comprises an antigen.

9. The microfluidic chip of claim 1, wherein the microfluidic chip comprises more than one incubation chamber and each incubation chamber comprises a different antigen.

10. The microfluidic chip of claim 8, wherein: a) the antigen is selected from Table 1; b) at least 2 different antigens are selected from Table 1; c) the same antigen is included in three or four different incubation chambers; d) the antigen is bound to a microbead; e) at least one incubation chamber comprises a marker used to detect pregnancy; f) at least one incubation chamber comprises a marker used to type blood; g) at least one incubation chamber comprising a marker to measure: 1. CBC measurements; i. White Blood Cell fractions; ii. Hemoglobin levels; and/or iii. Platelet levels; 2. Human chorionic gonadotropin (hCG); 3. Blood serum or plasma viscosity; 4. Blood typing; 5. Serologic cross-matching; 6. Yeast; 7. A primary cell; 8. A cancer cell; 9. A stem cell; 10. A differentiation factor; 11. An antibody; 12. An allergen; 13. A drug; 14. A substance used to monitor the change of signal, morphology, cytotoxicity or collecting secreting substance; 15. Static droplet arrays; and/or 16. Cell free tumor or viral DNA.

11. The microfluidic chip of claim 1, wherein the microfluidic chip comprises a polymer, glass, silicon, metal or combination thereof.

12. The microfluidic chip of claim 11, wherein the polymer is selected from: (poly) dimethylsiloxane (PDMS), cyclic olefin copolymer (COC), polyethylene, Polytetrafluoroethylene (PTFE), polyethylene terephthalate (PET), biaxially-oriented polyethylene terephthalate, or other polymer, hydrogel, glass, or metal.

13. The microfluidic chip of claim 1, wherein the microchip further comprises a valve capable of controlling the solution's flow direction.

14. The microfluidic chip of claim 13, wherein the valve dynamically changes the flow direction.

15. The microfluidic chip of claim 13, wherein the valve intermittently switches the flow direction of R2.

16. The microfluidic chip of claim 13, wherein the valve is switched when the solution reaches a row's last sequentially ordered seat.

17. The microfluidic chip of claim 13, wherein the valve is switched when the sample reaches the chamber's last sequentially ordered seat of all odd or even rows.

18. A kit comprising the microfluidic chip of claim 1 and a detecting agent.

19. The kit of claim 18, wherein the kit further comprises: a) a solution comprising an antibody capable of detecting an immune response; b) a solution comprising an antibody capable of binding to a protein selected from: IgGs, IgEs, histamine, IL-2, IL-4, IL-13, tryptase, or LTC4; c) a solution capable of detecting a substance in the biological sample; and/or d) the substance of c) selected from: 1) A WBC; a platelet; a primary cell; a cancer cell; a stem cell; 2) Hgb, a differentiation factor, an antibody, an allergen, a drug, human chorionic gonadotropin (hCG), IgGs, IgEs, histamine, IL-2, IL-4, IL-13, tryptase, or LTC4, or a substance used to monitor the change of signal, morphology, cytotoxicity, or levels of a secreted substance; 3) A microorganism; and/or 4) A droplet containing various physio-chemical and/or biological substances.

20. A method of detecting a particle in a solution comprising: a) placing the solution thought to comprise a particle in the incubation inlet of the microfluidic chip of claim 1; b) adding a second solution capable of detecting the particle; c) processing the solution through a readout chamber to detect the presence of the particle in the solution.

21. The method of claim 20, wherein: a) the solution comprises a biological sample obtained from a patient, and the biological sample is placed on the microfluidic chip wherein the biological sample comes in contact with an antigen; and the presence or absence an immune response is measured; b) the second solution comprises an antibody capable of detecting an immune response; c) the antibody of (b) capable of binding to a protein selected from: IgGs, IgEs, histamine, IL-2, IL-4, IL-13, tryptase, or LTC4; d) the immune response is measured by a fluorescence microscope, surface plasmon resonance, bead-based solid phase detection methodologies, or colorimetric absorbance methodologies; and/or e) a greater than 95%, 96%, 97%, 98%, 99% sensitivity and/or specificity is obtained.

22. The method of claim 20, wherein the following particles are detected in the solution: 1) A WBC; a platelet; a primary cell; a cancer cell; a stem cell; 2) Hgb, a differentiation factor, an antibody, an allergen, a drug, human chorionic gonadotropin (hCG), IgGs, IgEs, histamine, IL-2, IL-4, IL-13, tryptase, or LTC4, or a substance used to monitor the change of signal, morphology, cytotoxicity, or levels of a secreted substance; and/or 3) A microorganism.

Description

BRIEF DESCRIPTION OF DRAWINGS

(1) FIG. 1 shows the top view of the general structure of one exemplified chip, with black lines representing fluidic channels in the bottom layer and red lines representing fluidic channels in the top layer. The exemplified chip is divided into three sections such as an incubation chamber A, a washing chamber B, and a readout chamber C. The outlets of the first two chambers are connected to the inlet of the following chambers via a bridge 4.

(2) FIG. 2 shows a magnified sketch of the bottom layer of the incubation or washing chambers, which have identical structures. There is an outer channel 9 (cellular incubation channel) and a center channel 10 (microbead analyte capture channel).

(3) FIG. 3 shows the magnified sketch of the top layer. There are holes in the ends of channels 6 and 7, which connect to the center channels of the bottom layer.

(4) FIG. 4 shows the bottom layer at higher magnification for further detail.

(5) FIG. 5 shows a one-way readout chamber in which individual microbeads 11 are captured in evenly spaced seats.

(6) FIG. 6 shows the principle of the one-way readout chamber.

(7) FIG. 7 shows a one-way readout chamber fully filled with microbeads 11.

(8) FIG. 8 shows the embodiment of the two-way readout chamber.

(9) FIG. 9 shows the valve position 15 for filling the even rows of a two-way readout chamber.

(10) FIG. 10 shows a two-way readout chamber fully filled with microbeads.

(11) FIG. 11 shows a schematic of an exemplified imaging setup, including the excitation light source (a red or UV light-emitting diode (LED)), the microfluidic chip on the robotic x-y-z stage, and the location of the camera.

(12) FIG. 12 shows a photograph of an exemplified prototype of the microfluidic chip, made of PDMS (a). Magnified view of the incubation chamber shown in (b) and the readout chamber shown in (c).

(13) FIG. 13 depicts an example of an individual microwell bi-well insert, which is comprised of a porous vertical fluidic barrier 16, cellular incubation chamber 17, and well access for the washing chamber 18.

(14) FIG. 14 indicates bi-well insert placed into microplate 19.

(15) FIG. 15 shows a whole microplate bi-well insert.

(16) FIG. 16 depicts a microwell plate with built-in bi-well fluidic barrier 20.

DETAILED DESCRIPTION

(17) The details of one or more embodiments of the invention are set forth in the accompanying drawings and the description below. Other features, objects, and advantages of the invention will be apparent from the description and drawings, and from the claims.

(18) Before describing the present invention in detail, it is to be understood that this invention is not limited to particularly exemplified materials or process parameters as such may, of course, vary. It is also to be understood that the terminology used herein is for the purpose of describing particular embodiments of the invention only, and is not intended to be limiting of the use of alternative terminology to describe the present invention.

Definitions

(19) Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by those of ordinary skill in the art, such as in the arts of peptide chemistry, cell culture and phage display, nucleic acid chemistry, and biochemistry. Standard techniques are used for molecular biology, genetic, and biochemical methods (see Sambrook et al., Molecular Cloning: A Laboratory Manual, 3rd ed., 2001, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY; Ausubel et al., Short Protocols in Molecular Biology (1999) 4.sup.th ed., John Wiley & Sons, Inc.), which are incorporated herein by reference.

(20) As used herein, microfluidic chip or chip is defined as a lab-on-a-chip that comprises at least one channel with an input and an output and at least one chamber that allows the loading of small volumes of biological samples or fluids. The chamber of the chip can be preloaded with any antigens, allergens, and biomarkers. Examples of microchips are described herein.

(21) As used herein, a microwell is a chamber in a microtiter plate that is designed to hold liquid volumes between 10 microliters and 10 milliliters. A plate may contain 6, 12, 24, 48, 96, or 384 microwells.

(22) As used herein, a bi-well insert is a structure comprising a porous vertical fluidic barrier that divides a microwell into two compartments that remain in contact through the aqueous phase, allowing diffusion of soluble molecules. As shown in FIG. 13, a bi-well insert comprises a vertical porous fluidic barrier 16, a cellular incubation chamber 17 containing an inlet, and a washing/capture chamber 18 also containing an inlet, wherein the inlet of the incubation chamber 17 and the washing/capture chamber 18 also functions as an outlet. In preferred embodiments, a bi-well insert can be individually made and plugged into a microwell (see, e.g., FIG. 14). In further preferred embodiments, multiple bi-well inserts integrate to form a whole plate insert which conveniently provides bi-wells for the entire plate (see, e.g. FIG. 15-16).

(23) As used herein, a fluidic barrier is defined as a structure that blocks particles (e.g., such as microbeads and red blood cells) of a desired size while allowing for the diffusion of smaller molecules. In preferred embodiments, a fluidic barrier comprises micro-pillars. The distance between the micro-pillars will determine the size cut-off for particles that can diffuse between the channels. Thus, the fluidic barrier provides fluidic resistance as well as a means of preventing the direct mixing of the sample and a target. Due to the fluidic resistance provided by the micro-pillar, the majority of fluid moves independently. Other similar structures such as porous membranes, porous walls, hydrogels, micro/nano-grids, or PVDF-PZT composite can substitute for the micro-pillar as long as they can provide similar functions.

(24) As used herein, a channel is defined as a rectangular, circular, or tubular enclosed passage or conduit that allows fluidic substances to pass. As used herein, an outer channel is a channel that transports fluidic substances around another channel from which it is separated by pillars 8 or other fluidic barriers as shown in FIG. 4. As used herein, a center channel 10 is a channel that is surrounded by the outer channels 9 as shown in FIG. 4. As shown in FIG. 4, the channels may be arranged as concentric channels.

(25) As used herein, an inlet and/or an outlet refers to a structure allowing the entrance and/or exit of fluidic substances. In some embodiments, the inlet and the outlet are the same.

(26) As used herein, chamber is defined as an artificial reservoir or cavity where fluids are collected and stored for use. Assays are conducted in these chambers to determine the presence and amount of one or more biomarkers, e.g., biomarkers associated with an allergic response. As shown in the figures, an incubation chamber A is where physical and/or chemical reactions between substances occur and real-time analyte capture takes place. A washing chamber B is where microbeads are exposed to a fresh solution to remove unnecessary or unwanted materials from/around the microbeads. A read-out chamber C is where samples are arranged and organized to be investigated under an imaging setup.

(27) As used herein, bridge refers to a channel, which connects the outlet of a chamber to the inlet of another chamber.

(28) As used herein, a seat 13 is defined as a structure that can immobilize or trap an object as shown in FIG. 6.

(29) As used herein, a flow guide structure 14 refers to an impenetrable barrier that determines the direction of flow as shown in FIG. 6.

(30) As used herein, (Poly) dimethylsiloxane, abbreviated as PDMS, is defined as a group of polymeric organosilicon compounds that are commonly referred to as silicones. PDMS is the most widely used silicon-based organic polymer, and is particularly known for its unusual rheological (or flow) properties. PDMS is optically clear, and, in general, inert, non-toxic, and non-flammable. It is also called dimethicone and is one of several types of silicone oil (polymerized siloxane). The chemical formula for PDMS is CH.sub.3[Si(CH.sub.3).sub.2O].sub.nSi(CH.sub.3).sub.3, where n is the number of repeating monomer [SiO(CH.sub.3).sub.2] units.

(31) As used herein, Polyethylene (abbreviated PE) or polythene (IUPAC name polyethene or poly(methylene)) is defined as the most common plastic. Many kinds of polyethylene are known, with most having the chemical formula (C.sub.2H.sub.4).sub.n. Thus PE is usually a mixture of similar organic compounds that differ in terms of the value of n.

(32) As used herein, Teflon, also called Polytetrafluoroethylene (PTFE), is defined as a synthetic fluoropolymer of tetrafluoroethylene that has numerous applications. The best known brand name of PTFE-based formulas is Teflon by DuPont Co.

(33) As used herein, Cyclo olefin copolymer (abbreviated COC), also called Cyclo olefin polymer (abbreviated COP), is defined as a polymer or mixture of polymers produced from a cyclic monomer or monomers. The best known brand name of COC is TOPAS Advanced Polymer's TOPAS.

(34) As used herein, Polyvinylidene fluoride-lead zirconate titanate composite (abbreviated PVDF-PZT composite), is defined as a composite material that combines the excellent piezoelectric properties of ceramics with the flexibility and strength of polymers resulting in relatively high dielectric permittivity and breakdown strength.

(35) As used herein, Mylar, also called BoPET (Biaxially-oriented polyethylene terephthalate), is defined as a polyester film made from stretched polyethylene terephthalate (PET) and is used for its high tensile strength, chemical and dimensional stability, transparency, reflectivity, gas and aroma barrier properties, and electrical insulation. A variety of companies manufacture boPET and other polyester films under different brand names. In the UK and US, the most well-known trade names are Mylar, Melinex, and Hostaphan.

(36) As used herein, hydrodynamic resistance is resistance against fluid flow. We use the analytical solution of Poiseuille flow in a rectangular channel to calculate the hydrodynamic resistance as shown below, where w is the width of the channel, h is the height of the channel, L is the length of the channel and u is the fluid viscosity,

(37) $R_f={\frac{12L}{{\mathrm{wh}}^3}\left[1-\frac{h}{w}\left(\frac{192}{{}^5}\underset{n=1,3,5}{\overset{}{.Math.}}\frac{1}{n^5}\tanh \left(\frac{nw}{2h}\right)\right)\right]}^{-1}$

(38) As used herein, static droplet arrays are evenly spaced aqueous or oil droplets (Mashaghi et al. Droplet microfluidics: A tool for biology, chemistry and nanotechnology, TrAC Trends in Analytical Chemistry, Volume 82, 2016, Pages 118-125; Clausell-Tormos et al. Droplet-Based Microfluidic Platforms for the Encapsulation and Screening of Mammalian Cells and Multicellular Organisms, Chemistry & Biology, Volume 15, Issue 5, 2008, Pages 427-437.

(39) As used herein, Deep learning is one of machine learning methods based on information processing and communication patterns in a biological nervous system. The data representations needed for feature classification are discovered via training from structured, semi-structured or unstructured raw data.

(40) As used herein Image recognition means to identify objects, features, or patterns from an image.

(41) As used herein, biological sample refers to any specimen taken from a patient. The biological sample can include, for example, peripheral blood, stool, saliva, urine, bone marrow, and/or tissue from a surgical resection. In a preferred embodiment, the biological sample is a peripheral blood sample. It is understood that the biological sample reflects the immunological state of the patient, including various biomarkers for allergic, immunological, and other physiological states.

(42) As used herein, antigen refers to any structural substance that, under appropriate conditions, induces a specific immune response and causes the immune system to produce antibodies. The antigen may originate from within the body or from the external environment such as chemicals, bacteria, viruses, and pollen. Antigen is recognized by highly variable antigen receptors such as B cell receptors or T cell receptors of the adaptive immune system.

(43) As used herein, allergen is defined as a type of antigen, most often eaten or inhaled, that generates a hypersensitive immune response and causes an allergic reaction. An allergen is capable of stimulating a type-I hypersensitivity reaction through immunoglobulin E (IgE), a type of antibody normally used as a defense against parasitic infections. Allergens can be found in a wide range of environmental sources. Table 1 provides a non-exhaustive list of potential allergens that can be placed in a chamber of the present invention.

(44) As used herein, parallel, in geometry, means two lines in a plane that do not intersect or touch each other at any point.

(45) As used herein, radially refers to a series of lines that meet at a central point in a circle, cylinder, or sphere.

(46) As used herein, marker, also used interchangeably with biomarker or biological marker, is defined as a measurable indicator of biological processes and biological states or conditions.

(47) As used herein, target, is defined as a substance or cell of interest that can be detected and quantified.

(48) As used herein, blood typing is defined as a method to classify the specific type of blood based on the presence or absence of inherited antigenic substances on the surface of red blood cells. The two most important human blood group systems are ABO (blood type A, B, O, or AB) and RhD antigen (positive, negative, or null).

(49) As used herein, the term serological cross-matching refers to a method involving mixing of donor blood, serum, or plasma against recipient blood, serum, or plasma to evaluate for transfusion compatibility.

(50) As used herein, the term complete blood count or CBC for short refers to a measure of the numbers of different types of blood cells in an individual's body. The measurement includes white blood cell count (WBC, leukocyte), white blood cell types (WBC differential), red blood cell count, hematocrit (HCT, packed cell volume, PCV), hemoglobin, red blood cell indices, platelet count, and mean platelet volume.

(51) As used herein, polymer is defined as a macromolecule consisting of a large number of similar subunits bonded together.

(52) As used herein, hydrogel is defined as a gel in which water is the dispersion medium. It is a network of hydrophilic polymer chains and is highly absorbent.

(53) As used herein, kit refers to any collection of items or components needed for the use of the microfluidic chip.

(54) As used herein, solution is defined as a homogeneous liquid mixture that contains two or more substances.

(55) As used herein, antibody refers to immunoglobulin molecules and immunologically active portions of immunoglobulin molecules, i.e., molecules that contain an antigen binding site that immunospecifically binds peptide or protein. As such, the term antibody encompasses not only whole antibody molecules, but also antibody fragments as well as variants (including derivatives) of antibodies and antibody fragments. Examples of molecules that are described by the term antibody in this application include, but are not limited to: single chain Fvs (scFvs), Fab fragments, Fab fragments, F(ab)2, disulfide linked Fvs (sdFvs), Fvs, and fragments comprising or alternatively consisting of, either a VL or a VH domain. The term single chain Fv or scFv as used herein refers to a polypeptide comprising a VL domain of an antibody linked to a VH domain of an antibody.

(56) Additionally, antibodies of the invention include, but are not limited to, monoclonal, multi-specific, bi-specific, human, humanized, mouse, or chimeric antibodies, single chain antibodies, Fab fragments, F(ab) fragments, anti-idiotypic (anti-Id) antibodies (including, e.g., anti-Id antibodies to antibodies of the invention), domain antibodies, and epitope-binding fragments of any of the above. The immunoglobulin molecules of the invention can be of any class (e.g., IgG, IgE, IgM, IgD, IgA and IgY) or subclass (e.g., IgG1, IgG2, IgG3, IgG4, IgA1 and IgA2) of immunoglobulin molecule.

(57) As used herein, immune response is defined as the humoral immune response and/or the cell-mediated immune response to an antigen. In the humoral immune response, B lymphocytes produce antibodies that react with processed antigens. In the cell-mediated immune response, T lymphocytes activate macrophages and other immune cells in the presence of processed antigens.

(58) As used herein, allergic response is defined as a hypersensitivity immune reaction triggered by substances (allergens) that are normally harmless or would only cause an immune response in certain individuals. Immunoglobulin E is produced in response to the presence of each allergen and causes cells to generate histamines and other substances that produce symptoms of allergic reactions.

(59) As used herein, fluorescent refers to a substance that absorbs light and then re-emits it at the same or longer wavelength. Fluorescent substances can be conjugated to antibodies in order to enable detection of antibody binding.

(60) As used herein, surface plasmon resonance refers to the resonant oscillation of conduction electrons at the interface between a negative and positive permittivity material stimulated by incidence light. A surface plasmon is an electro-magnetic wave propagating along the surface of a thin metal layer and the resonance conditions are influenced by the material adsorbed onto the thin metal film. The surface plasmon resonance is expressed in resonance units and is therefore a measure of mass concentration at the sensor chip surface.

(61) As used herein, colorimetric refers to an assay in which a reagent undergoes a color change that indicates the presence of a substance of interest. As an example, an enzymatic colorimetric assay may involve an antibody linked to an enzyme that cleaves a substrate, leading to color change if the enzyme-linked antibody is present.

(62) As used herein, solid phase detection refers to an assay in which one substance is immobilized through binding to a solid surface and then potential binding partners are added in the liquid phase. Binding can be detected through colorimetric or fluorescent detection as described above.

(63) As used herein, bead based detection refers to an assay in which a substance is coupled to a bead and then exposed to potential binding partners. Again, detection of binding may be accomplished through fluorescent or colorimetric assays.

(64) As used herein, sensitivity when used in the context of describing a test refers to the ability of the test to detect a person who has the quality or disease being interrogated by the test. The sensitivity can be described as the true positive rate of a test. For example, in the context of allergy, the sensitivity of a test refers to the probability of having a positive result in a person who has the allergy being tested.

(65) As used herein, specificity when used in the context of describing a test refers to the ability of the test to correctly identify those who do not have the quality or disease being tested. The specificity is also described as the true negative rate of the test.

(66) Table 1 provides a list of potential allergens that can be placed in a chamber of the present invention. Column 1 of Table 1 provides the common name of each allergen. Column 2 lists the species and Column 3 (IUIS Allergen) provides the systemic allergen nomenclature established by the World Health Organization and International Union of Immunological Societies (WHO/IUIS). Column 4 describes the type of allergen and Column 5 provides the structurally related allergens from different species within the same genus, or from closely related genera. Column 6 shows the protein length of the allergen and Column 7 correlates the GenBank Accession Number (GI #) with each allergen. Each allergen shown on Table 1 can be placed in a chamber on the chip of the present invention. Moreover, combinations of different allergens shown in each row of Table 1 can be included in different chambers on the chip of the present invention. The number of allergens that can be included in different chambers on a chip can vary depending on technical constraints, cost considerations, and/or the diagnosis being made. Thus in some embodiments, the chip can comprise at least 1, 2, 3, 4, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 30, 31, 32, 33, 34, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, or 90 or more different allergens listed in each row of Table 1. Each chip can have different combinations of allergens, with each allergen being tested placed in different chambers on a single chip.

(67) TABLE-US-00001 Common Name Species IUIS Allergen Type Group Protein Length GI# Abalone Haliotis diversicolor Unassigned Food Animal Haliotis Hal m 1 tropomyosin 284 9954249 Alaska pollock Theragra chalcogramma Unassigned Food Animal Theragra parvalbumin 109 14531020 Alaska pollock Theragra chalcogramma Unassigned Food Animal Theragra parvalbumin 109 14531018 Alder Alnus glutinosa Aln g 1 Aero Plant Alnus Aln g 1 160 261407 Alder Alnus glutinosa Aln g 1.0101 Aero Plant Alnus Aln g 4 85 3319651 Almond Prunus dulcis Unassigned Food Plant Prunus persica Pru p 2 IUIS 241 190613941 Almond Prunus dulcis Pru du 4.0101 Food Plant Prunus Pru 4 Profilin peach cherry almond 131 24473794 Almond Prunus dulcis Unassigned Food Plant Prunus Pru du 6 Amandin 531 258588247 Almond Prunus dulcis Unassigned Food Plant Prunus Pru du 6 Amandin 178 523916668 Almond Prunus dulcis Pru du 6.0101 Food Plant Prunus Pru du 6 Amandin 551 307159112 Almond Prunus dulcis Pru du 6.0201 Food Plant Prunus Pru du 6 Amandin 504 307159114 Almond Prunus dulcis Unassigned Food Plant runus Seed allergenic protein 2 (Conglutin gamma 25 75107131 American cockroach Periplaneta americana Unassigned Aero Insect Periplaneta GST 216 60678789 American cockroach Periplaneta americana Unassigned Aero Insect Periplaneta GST 216 359326557 American cockroach Periplaneta americana Per a 7.0102 Aero Insect Periplaneta Per 7 284 4378573 American cockroach Periplaneta americana Per a 7.0101 Aero Insect Periplaneta Per 7 284 4468639 American cockroach Periplaneta americana Unassigned Aero Insect Periplaneta Per 7 284 239740599 American cockroach Periplaneta americana Per a 1.0201 Aero Insect Periplaneta Per a 1 446 2231297 American cockroach Periplaneta americana Per a 1.0104 Aero Insect Periplaneta Per a 1 274 2253610 American cockroach Periplaneta americana Per a 1.0103 Aero Insect Periplaneta Per a 1 395 2580504 American cockroach Periplaneta americana Per a 1.0102 Aero Insect Periplaneta Per a 1 228 2897849 American cockroach Periplaneta americana Per a 1.0101 Aero Insect Periplaneta Per a 1 231 4240399 American cockroach Periplaneta americana Unassigned Aero Insect Periplaneta Per a 1 124 30144660 American cockroach Periplaneta americana Unassigned Aero Insect Periplaneta Per a 1 395 284518361 American cockroach Periplaneta americana Per a 10.0101 Aero Insect Periplaneta Per a 10 ser protease 256 60678799 American cockroach Periplaneta americana Unassigned Aero Insect Periplaneta Per a 2 351 60678785 American cockroach Periplaneta americana Per a 2.0101 Aero Insect Periplaneta Per a 2 351 313870534 American cockroach Periplaneta americana Per a 3.0201 Aero Insect Periplaneta Per a 3 631 1531589 American cockroach Periplaneta americana Per a 3.0202 Aero Insect Periplaneta Per a 3 470 1580794 American cockroach Periplaneta americana Per a 3.0203 Aero Insect Periplaneta Per a 3 393 1580797 American cockroach Periplaneta americana Per a 3.0101 Aero Insect Periplaneta Per a 3 685 2833325 American cockroach Periplaneta americana Unassigned Aero Insect Periplaneta Per a 3 688 284518363 American cockroach Periplaneta americana Unassigned Aero Insect Periplaneta Per a 3 685 289721058 American cockroach Periplaneta americana Unassigned Aero Insect Periplaneta Per a 4 183 60678787 American cockroach Periplaneta americana Unassigned Aero Insect Periplaneta Per a 4 163 215794707 American cockroach Periplaneta americana Unassigned Aero Insect Periplaneta Per a 4 167 212675312 American cockroach Periplaneta americana Per a 6.0101 Aero Insect Periplaneta Per a 6 151 60678791 American cockroach Periplaneta americana Unassigned Aero Insect Periplaneta Per a 9 356 50428904 American cockroach Periplaneta americana Per a 9.0101 Aero Insect Periplaneta Per a 9 356 167782135 American lobster Homarus americanus Hom a 1.0102 Food Animal Homarus Hom a 1 284 2660868 American lobster Homarus americanus Hom a 1.0101 Food Animal Homarus Hom a 1 284 2660866 American oyster Crassostrea gigas Unassigned Food Animal Crassostrea Tropomyosin 233 15419048 American oyster Crassostrea gigas Unassigned Food Animal Crassostrea Tropomyosin 284 219806594 Annual mercury grass Mercurialis annua Mer a 1 Aero Plant Mercurialis Mer a 1 133 2959898 Apple Malus x domestica Mal d 1.0301 Food Plant Malus Mal d 1 159 1313966 Apple Malus x domestica Mal d 1.0401 Food Plant Malus Mal d 1 160 1313968 Apple Malus x domestica Mal d 1.0402 Food Plant Malus Mal d 1 160 1313970 Apple Malus x domestica Mal d 1.0403 Food Plant Malus Mal d 1 160 1313972 Apple Malus x domestica Mal d 1.0206 Food Plant Malus Mal d 1 159 2443824 Apple Malus x domestica Mal d 1.0103 Food Plant Malus Mal d 1 159 4590364 Apple Malus x domestica Mal d 1.0203 Food Plant Malus Mal d 1 159 4590366 Apple Malus x domestica Mal d 1.0204 Food Plant Malus Mal d 1 159 4590368 Apple Malus x domestica Mal d 1.0104 Food Plant Malus Mal d 1 159 4590376 Apple Malus x domestica Mal d 1.0105 Food Plant Malus Mal d 1 159 4590378 Apple Malus x domestica Mal d 1.0106 Food Plant Malus Mal d 1 159 4590380 Apple Malus x domestica Mal d 1.0107 Food Plant Malus Mal d 1 159 4590382 Apple Malus x domestica Mal d 1.0205 Food Plant Malus Mal d 1 159 4590388 Apple Malus x domestica Mal d 1.0208 Food Plant Malus Mal d 1 158 21685277 Apple Malus x domestica Mal d 1.0304 Food Plant Malus Mal d 1 159 27922941 Apple Malus x domestica Mal d 1.0108 Food Plant Malus Mal d 1 159 4768879 Apple Malus x domestica Mal d 1.0201 Food Plant Malus Mal d 1 159 862307 Apple Malus x domestica Mal d 1.0102 Food Plant Malus Mal d 1 159 886683 Apple Malus x domestica Mal d 1.0101 Food Plant Malus Mal d 1 159 747852 Apple Malus x domestica Mal d 1.0109 Food Plant Malus Mal d 1 159 15418742 Apple Malus x domestica Mal d 1.0207 Food Plant Malus Mal d 1 159 15418744 Apple Malus x domestica Mal d 1.0302 Food Plant Malus Mal d 1 159 15418738 Apple Malus x domestica Unassigned Food Plant Malus Mal d 2 26 1478293 Apple Malus x domestica Unassigned Food Plant Malus Mal d 2 246 60418842 Apple Malus x domestica Unassigned Food Plant Malus Mal d 2 246 60418848 Apple Malus x domestica Unassigned Food Plant Malus Mal d 2 246 30316292 Apple Malus x domestica Unassigned Food Plant Malus Mal d 2 158 218059718 Apple Malus x domestica Unassigned Food Plant Malus Mal d 2 158 218059715 Apple Malus x domestica Unassigned Food Plant Malus Mal d 2 193 392507603 Apple Malus x domestica Mal d 2.0101 Food Plant Malus Mal d 2 245 3643249 Apple Malus x domestica Unassigned Food Plant Malus Mal d 3 115 50659891 Apple Malus x domestica Unassigned Food Plant Malus Mal d 3 115 50659889 Apple Malus x domestica Unassigned Food Plant Malus Mal d 3 115 50659885 Apple Malus x domestica Unassigned Food Plant Malus Mal d 3 115 50659879 Apple Malus x domestica Unassigned Food Plant Malus Mal d 3 115 50659859 Apple Malus x domestica Unassigned Food Plant Malus Mal d 3 115 38492338 Apple Malus x domestica Unassigned Food Plant Malus Mal d 3 115 14423814 Apple Malus x domestica Mal d 4.0302 Food Plant Malus Mal d 4 131 28881453 Apple Malus x domestica Mal d 4.0102 Food Plant Malus Mal d 4 131 28881457 Apple Malus x domestica Mal d 4.0202 Food Plant Malus Mal d 4 131 28881455 Apple Malus x domestica Unassigned Food Plant Malus Mal d 4 131 60418854 Apple Malus x domestica Unassigned Food Plant Malus Mal d 4 131 60418858 Apple Malus x domestica Unassigned Food Plant Malus Mal d 4 131 60418862 Apple Malus x domestica Unassigned Food Plant Malus Mal d 4 131 60418866 Apple Malus x domestica Unassigned Food Plant Malus Mal d 4 131 164510842 Apple Malus x domestica Unassigned Food Plant Malus Mal d 4 131 164510858 Apple Malus x domestica Unassigned Food Plant Malus Mal d 4 131 164510860 Apple Malus x domestica Unassigned Food Plant Malus Mal d 4 77 218059730 Apple Malus x domestica Unassigned Food Plant Malus Mal d 4 115 218059733 Apple Malus x domestica Unassigned Food Plant Malus Mal d 4 131 218059728 Apple Malus x domestica Mal d 4.0301 Food Plant Malus Mal d 4 131 4761584 Apple Malus x domestica Mal d 4.0201 Food Plant Malus Mal d 4 131 4761586 Apple Malus x domestica Mal d 4.0101 Food Plant Malus Mal d 4 131 4761588 Apricot Prunus armeniaca Pru ar 1 Food Plant Prunus PRP (Bet v 1 family) 160 2677826 Apricot Prunus armeniaca Unassigned Food Plant Prunus Pru 3 119 313575730 Apricot Prunus armeniaca Unassigned Food Plant Prunus Pru 3 117 313575732 Apricot Prunus armeniaca Pru ar 3.0101 Food Plant Prunus Pru 3 117 313575734 Apricot Prunus armeniaca Unassigned Food Plant Prunus Pru 3 117 313575736 Arizona Cypress Cupressus arizonica Cup a 1 Aero Plant Cupressus Cup a 1/Cup s 1 346 6562326 Arizona Cypress Cupressus arizonica Cup a 1 Aero Plant Cupressus Cup a 1/Cup s 1 367 19069497 Arizona Cypress Cupressus arizonica Unassigned Aero Plant Cupressus Cup a 1/Cup s 1 347 118197955 Arizona Cypress Cupressus arizonica Unassigned Aero Plant Cupressus Cup a 4 165 261865475 Arizona Cypress Cupressus arizonica Unassigned Aero Plant Cupressus Cup s 3 199 9929163 Arthropod Protortonia cacti Unassigned Food Animal Protortonia 335 237769615 Asian green mussell Perna viridis Unassigned Food Animal Perna Tropomyosin 284 9954251 Asian needle ant Pachycondyla chinensis Unassigned Venom or Pachycondyla Pac c 3 allergen 199 169822894 Asian sea bass Lates calcarifer Lat c 1.0101 Food Animal Lates Lat c 1 109 56553743 Asian sea bass Lates calcarifer Lat c 1.0201 Food Animal Lates Lat c 1 109 48526356 Atlantic cod Gadus morhua Gad m 1.0101 Food Animal Gadus Gad c 1 Gad m 1 109 14531014 Atlantic cod Gadus morhua Gad m 1.0201 Food Animal Gadus Gad c 1 Gad m 1 109 14531016 Atlantic cod Gadus morhua Gad m 1.0102 Food Animal Gadus Gad c 1 Gad m 1 109 148356691 Atlantic cod Gadus morhua Gad m 1.0202 Food Animal Gadus Gad c 1 Gad m 1 109 148356693 Atlantic cod Gadus morhua Gad m 2.0101 Food Animal Gadus Morhua Gad m 2 11 576011130 Atlantic cod Gadus morhua Gad m 3.0101 Food Animal Gadus morhua Gad m 3 15 576011086 Atlantic herring Clupea harengus Clu h 1.0101 Food Animal Clupea Clu h 1 109 242253963 Atlantic herring Clupea harengus Clu h 1.0201 Food Animal Clupea Clu h 1 110 242253965 Atlantic herring Clupea harengus Clu h 1.0301 Food Animal Clupea Clu h 1 109 242253967 Atlantic mackerel Scomber scombrus Unassigned Food Animal Scomber Parvalbumin 109 288557436 Avocado Persea americana Pers a 1 Aero Plant Persea Pers a 1 326 3201547 Bacteria Bacillus lentus Unassigned Bacteria airway Bacillus lentus subtilisin 269 267048 Bacteria Bacillus licheniformis Unassigned Bacteria airway Bacillus licheniformis subtlilisin 379 135016 Bacteria Bacillus licheniformis Unassigned Bacteria airway Bacillus licheniformis subtlilisin 374 11127680 Bacteria Bacillus sp. Unassigned Bacteria airway Bacillus lentus Esperase 361 1225905 Bacteria Staphylococcus aureus Unassigned Bacteria skin Staphylococcus enterotoxin SEA 233 1633233 Bacteria Staphylococcus aureus Unassigned Bacteria skin Staphylococcus enterotoxin SEB 254 83308249 Bacteria Staphylococcus aureus Unassigned Bacteria skin Staphylococcus enterotoxin SEC 266 462026 Bacteria Staphylococcus aureus Unassigned Bacteria skin Staphylococcus enterotoxin SED 258 119654 Bacteria Staphylococcus aureus Unassigned Bacteria skin Staphylococcus enterotoxin TSST 1 234 136457 Bahia grass Paspalum notatum Unassigned Aero Plant Paspalum group 13 pollen allergen 169 338930686 Bahia grass Paspalum notatum Unassigned Aero Plant Paspalum group 13 pollen allergen 169 338930684 Bahia grass Paspalum notatum Unassigned Aero Plant Paspalum group 13 pollen allergen 169 338930682 Bahia grass Paspalum notatum Unassigned Aero Plant Paspalum group 13 pollen allergen 169 338930680 Bahia grass Paspalum notatum Unassigned Aero Plant Paspalum group 13 pollen allergen 393 338930678 Bahia grass Paspalum notatum Unassigned Aero Plant Paspalum group 13 pollen allergen 393 338930676 Bahia grass Paspalum notatum Unassigned Aero Plant Paspalum group 13 pollen allergen 391 338930674 Bahia grass Paspalum notatum Unassigned Aero Plant Paspalum group 13 pollen allergen 395 338930672 Bahia grass Paspalum notatum Pas n 1.0101 Aero Plant Paspalum Pas n 1 beta expansin 265 168419914 Balsam of Peru Plant Baltic cod Gadus callarias Gad c 1 Food Animal Gadus Gad c 1 Gad m 1 113 131112 Banana Musa acuminata Unassigned Food Plant Musa Allergen Endo-Beta-1,3-Glucanase 312 83754908 Banana Musa acuminata Mus a 4.0101 Food Plant Musa Mus a 4 200 88191901 Banana Musa acuminata Mus a 2.0101 Food Plant Musa Mus s 2 318 17932710 Banana Musa acuminata Mus xp 1 Food Plant Musa profilin banana 131 14161635 Banana Musa acuminata AAA Group Unassigned Food Plant Musa Allergen Endo-Beta-1,3-Glucanase 340 6073860 Banana Prawn Fenneropenaeus merguiensis Unassigned Food Animal Fenneropenaeus hemocyanin banana shrimp 661 530340505 Banana Prawn Fenneropenaeus merguiensis Unassigned Food Animal Fenneropenaeus enolase 117 344049993 Barley Hordeum vulgare Unassigned Aero Plant Hordeum Alpha-amylase inhibitor component 149 585290 Barley Hordeum vulgare Unassigned Aero Plant Hordeum LTP 1 117 167077 Barley Hordeum vulgare Unassigned Aero Plant Hordeum Trypsin inhibitor CMe 144 1405736 Barley Hordeum vulgare subsp vulgare Unassigned Aero Plant Hordeum Alpha-amylase inhibitor BDAI-1 152 3367714 Barley Hordeum vulgare subsp vulgare Unassigned Aero Plant Hordeum Alpha-amylase inhibitor component 144 18955 Barley Hordeum vulgare subsp vulgare Unassigned Aero Plant Hordeum Alpha-amylase inhibitor component 145 439275 Barley Hordeum vulgare subsp vulgare Unassigned Aero Plant Hordeum Trypsin inhibitor CMe 148 19009 Barley Hordeum vulgare Unassigned Food Plant Hordeum Hor v 20 289 1708280 Barley Hordeum vulgare Hor v 20.0101 Food Plant Hordeum Hor v 20 286 288709 Barley Hordeum vulgare Unassigned Food Plant Hordeum LTP 1 134 19039 Barley Hordeum vulgare subsp vulgare Hor v 15.0101 Food Plant Hordeum Hor v 15 146 19003 Bell pepper Capsicum annuum Cap a 1 Food Plant Capsicum Cap a 1 246 16609959 Bell pepper Capsicum annuum Cap a 2 Food Plant Capsicum Cap a 2 131 16555785 Benguela hake Merluccius polli Unassigned Food Anima Merluccius sp. Parvalbumin Hake 108 308191471 Benguela hake Merluccius polli Unassigned Food Animal Merluccius sp. Parvalbumin Hake 69 308191484 Bent grass Agrostis alba Unassigned Aero Plant Agrostis Agr a 1 26 320606 Bent grass Agrostis alba Unassigned Aero Plant Agrostis Agr a 1 35 75139987 Bent grass Agrostis alba Unassigned Aero Plant Agrostis Agr a 1 35 75139989 Bermuda grass Cynodon dactylon Cyn d 1 Aero Plant Cynodon Cyn d 1 25 451274 Bermuda grass Cynodon dactylon Cyn d 1 Aero Plant Cynodon Cyn d 1 38 451275 Bermuda grass Cynodon dactylon Cyn d 1 Aero Plant Cynodon Cyn d 1 34 691726 Bermuda grass Cynodon dactylon Cyn d 1.0204 Aero Plant Cynodon Cyn d 1 244 10314021 Bermuda grass Cynodon dactylon Cyn d 1.0201 Aero Plant Cynodon Cyn d 1 244 15384338 Bermuda grass Cynodon dactylon Cyn d 1.0202 Aero Plant Cynodon Cyn d 1 262 16076693 Bermuda grass Cynodon dactylon Cyn d 1 Aero Plant Cynodon Cyn d 1 262 16076695 Bermuda grass Cynodon dactylon Cyn d 1.0203 Aero Plant Cynodon Cyn d 1 262 16076697 Bermuda grass Cynodon dactylon Cyn d 1.0101 Aero Plant Cynodon Cyn d 1 246 7687901 Bermuda grass Cynodon dactylon Cyn d 12 Aero Plant Cynodon Cyn d 12 131 2154730 Bermuda grass Cynodon dactylon Unassigned Aero Plant Cynodon Cyn d 7 71 1247373 Bermuda grass Cynodon dactylon Unassigned Aero Plant Cynodon Cyn d 7 73 1247375 Bermuda grass Cynodon dactylon Cyn d 7 Aero Plant Cynodon Cyn d 7 82 1871507 Bermuda grass Cynodon dactylon Unassigned Aero Plant Cynodon Group 4 like-allergen FAD-linked 522 41393750 Bigfin reef squid Sepioteuthis lessoniana Unassigned Food Animal Sepioteuthis tropomyosin 284 83715930 Birch Betula sp. Unassigned Aero Plant Betula Bet v 1 51 298736 Birch Betula sp. Unassigned Aero Plant Betula Bet v 1b 51 298737 biting midges Forcipomyia taiwana For t 1.0101 Venom or Forcipomyia For t 1 118 188572341 biting midges Forcipomyia taiwana For t 1.0101 Venom or Forcipomyia For t 2 325 188572343 Black Fire Ant Solenopsis richteri Sol r 2.0101 Venom or Solenopsis Sol i and Sol r Venom allergen II 119 6136162 Black Fire Ant Solenopsis richteri Sol r 3.0101 Venom or Solenopsis Venom allergen III 211 6136163 Black mulberry Morus nigra Mor n 3.0101 Food Plant Morus Mor n 3 mulberry LTP 91 288561913 Black tiger shrimp Penaeus monodon Pen m 1.0101 Food Animal Penaeus Pen m 1 tropomyosin 284 60892782 Black tiger shrimp Penaeus monodon Pen m 2 Food Animal Penaeus Pen m 2 356 27463265 Black tiger shrimp Penaeus monodon Unassigned Food Animal Penaeus Pen m 2 356 308154236 Black tiger shrimp Penaeus monodon Pen m 3.0101 Food Animal Penaeus Pen m 3 myosin light chain 177 317383196 Black tiger shrimp Penaeus monodon Pen m 4.0101 Food Animal Penaeus Pen m 4 sarcoplasmic calcium binding 193 317383198 Black walnut Juglans nigra Jug n 1.0101 Food Plant Juglans Jug r 1 Jug n 1 161 31321942 Black walnut Juglans nigra Jug n 2.0101 Food Plant Juglans Jug r 2 481 31321944 Blue hake Macruronus novaezelandiae Unassigned Food Animal Merluccius sp. Parvalbumin Hake 83 308191475 Blue Lupin Lupinus angustifolius Unassigned Food Plant Lupinus Lup an 1 conglutin beta 521 149208401 Blue Lupin Lupinus angustifolius Unassigned Food Plant Lupinus Lup an 1 conglutin beta 455 149208403 Blue Lupin Lupinus angustifolius Lup an 1.0101 Food Plant Lupinus Lup an 1 conglutin beta 611 169950562 blue swimmer crab Portunus pelagicus Por p 1.0101 Food Animal Portunus Por p 1 tropomyosin 284 448278534 Bovine Bos taurus Unassigned Aero Mite Vaccine 1364 27806257 Bovine Bos taurus Unassigned Food Animal Bos Alpha-s1 casein 93 162650 Bovine Bos taurus Unassigned Food Animal Bos Alpha-s1 casein 214 162794 Bovine Bos taurus Unassigned Food Animal Bos Alpha-s1 casein 76 162927 Bovine Bos taurus Bos d 9.0101 Food Animal Bos Alpha-s1 casein 214 30794348 Bovine Bos taurus Unassigned Food Animal Bos Alpha-s1 casein 205 159793197 Bovine Bos taurus Unassigned Food Animal Bos Alpha-s1 casein 172 159793201 Bovine Bos taurus Unassigned Food Animal Bos Alpha-s1 casein 129 159793217 Bovine Bos taurus Bos d 10.0101 Food Animal Bos Bos d 10 222 27806963 Bovine Bos taurus Unassigned Food Animal Bos Bos d 11 beta casein 224 162797 Bovine Bos taurus Unassigned Food Animal Bos Bos d 11 beta casein 224 162805 Bovine Bos taurus Unassigned Food Animal Bos Bos d 11 beta casein 224 459292 Bovine Bos taurus Unassigned Food Animal Bos Bos d 12 190 162811 Bovine Bos taurus Bos d 12.0101 Food Animal Bos Bos d 12 190 27881412 Bovine Bos taurus Unassigned Aero Animal Bos Bos d 2 172 2497701 Bovine Bos taurus Bos d 3 Aero Animal Bos Bos d 3 101 2493414 Bovine Bos taurus Unassigned Food Animal Bos Bos d 4 142 295774 Bovine Bos taurus Bos d 4.0101 Food Animal Bos Bos d 4 142 163283 Bovine Bos taurus Bos d 5 Food Animal Bos Bos d 5 178 520 Bovine Bos taurus Unassigned Food Animal Bos Bos d 5 14 162750 Bovine Bos taurus Unassigned Food Animal Bos Bos d 5 178 125910 Bovine Bos taurus Unassigned Food Animal Bos Bos d 5 178 195957138 Bovine Bos taurus Bos d 6 Food Animal Bos Bos d 6 607 162648 Bovine Bos taurus Unassigned Food Animal Bos Bos d 6 607 3336842 Bovine Bos taurus Unassigned Food Animal Bos lactotransferrin 708 30794292 Brazil nut Bertholletia excelsa Ber e 1 Food Plant Bertholletia Ber e 1 146 112754 Brazil nut Bertholletia excelsa Ber e 2 Food Plant Bertholletia Ber e 2 465 30313867 Brazilian Fire Ant Solenopsis saevissima Unassigned Venom or Solenopsis Sol g 4 Sol i 4 137 291092710 Brook trout Salvelinus fontinalis Unassigned Food Animal Salvelinus parvalbumin 109 288557438 Brook trout Salvelinus fontinalis Unassigned Food Animal Salvelinus parvalbumin 108 288557440 Brown garden snail Helix aspersa Hel as 1.0101 Food Animal Helix Hel as 1 tropomyosin 284 4468224 Brown shrimp Farfantepenaeus aztecus Pen a 1 Food Animal Farfantepenaeus Pen a 1 284 73532979 Buckwheat Fagopyrum esculentum Unassigned Food Plant Fagopyrum BW 8 kDa protein 133 17907758 Buckwheat Fagopyrum esculentum Unassigned Food Plant Fagopyrum Fag e 2 Fag t 2 127 61970231 Buckwheat Fagopyrum esculentum Fag e 2.0101 Food Plant Fagopyrum Fag e 2 Fag t 2 149 83416591 Buckwheat Fagopyrum esculentum Unassigned Food Plant Fagopyrum Legumin-like protein 565 29839254 Buckwheat Fagopyrum esculentum Unassigned Food Plant Fagopyrum Legumin-like protein 504 29839255 Buckwheat Fagopyrum esculentum Unassigned Food Plant Fagopyrum Legumin-like protein 538 29839419 Buckwheat Fagopyrum esculentum Fag e 3.0101 Food Plant Fagopyrum vicilin-like protein 136 146217148 Buckwheat Fagopyrum tataricum Unassigned Food Plant Fagopyrum BW 8 kDa protein 133 144228127 Buckwheat Fagopyrum tataricum Fag t 2.0101 Food Plant Fagopyrum Fag e 2 Fag t 2 149 320445237 Buckwheat Fagopyrum tataricum Unassigned Food Plant Fagopyrum Legumin-like protein 515 113200131 Bumblebee Bombus pennsylvanicus Bom p 1.0101 Venom or Bombus Bom p 1 136 47117013 Bumblebee Bombus pennsylvanicus Bom p 4.0101 Venom or Bombus Bom p 4 protease 243 75009997 Bumblebee Bombus terrestris Bom t 1.0101 Venom or Bombus Bom t 1 136 14423832 Bumblebee Bombus terrestris Unassigned Venom or Bombus Bom t 4 protease 20 313471465 Cabbage Brassica oleracea Unassigned Food Plant Brassica Bra o 3 LTP manual entry 20 1 Canary grass Phalaris aquatica Unassigned Aero Plant Phalaris Pha a 1 20 409328 Canary grass Phalaris aquatica Pha a 1 Aero Plant Phalaris Pha a 1 269 2498576 Canary grass Phalaris aquatica Pha a 5.0101 Aero Plant Phalaris Pha a 5 320 2498577 Canary grass Phalaris aquatica Unassigned Aero Plant Phalaris Pha a 5 305 2498578 Canary grass Phalaris aquatica Unassigned Aero Plant Phalaris Pha a 5 294 2498579 Canary grass Phalaris aquatica Unassigned Aero Plant Phalaris Pha a 5 175 2498580 Caridean shrimp Pandalus borealis Pan b 1.0101 Food Animal Pandalus Pan b 1 284 312831088 Carp Cyprinus carpio Cyp c 1.0101 Food Animal Cyprinus Cyp c 1 Parvalbumin 109 17977825 Carp Cyprinus carpio Cyp c 1.0201 Food Animal Cyprinus Cyp c 1 Parvalbumin 109 17977827 Carrot Daucus carota Unassigned Food Plant Daucus cyclophilin 171 373939374 Carrot Daucus carota Dau c 1.0101 Food Plant Daucus Dau c 1 168 1335877 Carrot Daucus carota Dau c 1.0102 Food Plant Daucus Dau c 1 154 1663522 Carrot Daucus carota Dau c 1.0103 Food Plant Daucus Dau c 1 154 2154732 Carrot Daucus carota Dau c 1.0104 Food Plant Daucus Dau c 1 154 2154734 Carrot Daucus carota Dau c 1.0105 Food Plant Daucus Dau c 1 154 2154736 Carrot Daucus carota Dau c 1.0201 Food Plant Daucus Dau c 1 154 18652047 Carrot Daucus carota Unassigned Food Plant Daucus Dau c 1 154 19912791 Carrot Daucus carota Dau c 1.0301 Food Plant Daucus Dau c 1 154 302379147 Carrot Daucus carota Unassigned Food Plant Daucus Dau c 1 154 302379149 Carrot Daucus carota Unassigned Food Plant Daucus Dau c 1 154 302379151 Carrot Daucus carota Unassigned Food Plant Daucus Dau c 1 154 302379153 Carrot Daucus carota Unassigned Food Plant Daucus Dau c 1 154 302379155 Carrot Daucus carota Unassigned Food Plant Daucus Dau c 1 154 302379157 Carrot Daucus carota Unassigned Food Plant Daucus Dau c 1 154 302379159 Carrot Daucus carota Dau c 4 Food Plant Daucus Dau c 4 134 18652049 Carrot Daucus carota Dau c 5.0101 Food Plant Daucus Dau c 5 isoflavone reductase 306 373939378 Carrot Daucus carota Unassigned Food Plant Daucus Dau c 5 isoflavone reductase 306 373939376 Cashew Anacardium occidentale Ana 0 1.0102 Food Plant Anacardium Ana o 1 536 21666498 Cashew Anacardium occidentale Ana 0 1.0101 Food Plant Anacardium Ana o 1 538 21914823 Cashew Anacardium occidentale Ana o 2 Food Plant Anacardium Ana o 2 457 25991543 Cashew Anacardium occidentale Ana o 3 Food Plant Anacardium Ana o 3 138 24473800 Cassava Manihot esculenta Unassigned Food Plant Manihot Man e 5.0101 177 21585695 Cassava Manihot esculenta Man e 5.0101 Food Plant Manihot Man e 5.0101 177 332713934 Castor bean Ricinus communis Ric c 1.0101 Food Plant Ricinus Ric c 1 258 21068 Cat Felis catus Fel d 1 Aero Animal Felis Fel d 1 Chain 1 88 1364212 Cat Felis catus Fel d 1 Aero Anima Felis Fel d 1 Chain 1 92 1364213 Cat Felis catus Fel d 1 Aero Animal Felis Fel d 1 Chain 1 92 1169665 Cat Felis catus Fel d 1.0101 Aero Animal Felis Fel d 1 Chain 1 92 163825 Cat Felis catus Unassigned Aero Animal Felis Fel d 1 Chain 1 88 114326420 Cat Felis catus Unassigned Aero Animal Felis Fel d 1 chain 2 107 395407 Cat Felis catus Fel d 1.0101 Aero Animal Felis Fel d 1 chain 2 109 163823 Cat Felis catus Fel d 2.0101 Aero Animal Felis Fel d 2 608 886485 Cat Felis catus Fel d 3 Aero Animal Felis Fel d 3 98 17939981 Cat Felis catus Fel d 4 Aero Anima Felis Fel d 4 186 45775300 Cat Felis catus Fel d 7.0101 Aero Animal Felis Fel d 7 180 301072397 Cat Felis catus Fel d 8.0101 Aero Anima Felis Fel d 8 latherin-like 228 303387468 Cedar Juniperus rigida Unassigned Aero Plant Juniperus Jun a 3 225 38456224 Cedar Juniperus rigida Unassigned Aero Plant Juniperus Jun a 3 225 38456222 Celery Apium graveolens Api g 1.0101 Food Plant Apium Api g 1 154 1346568 Celery Apium graveolens Api g 1.0201 Food Plant Apium Api g 1 159 14423646 Celery Apium graveolens Api g 2.0101 Food Plant Apium Api g 2 118 256600126 Celery Apium graveolens Api g 4 Food Plant Apium Api g 4 134 4761578 Celery Apium graveolens Api g 5.0101 Food Plant Apium Api g 5 86 33300920 Celery Apium graveolens Rapaceum Group Api g 6.0101 Food Plant Apium graveolens Api g 6 LTP 2 67 550540827 Cephalosporins Chemical Cherry Prunus avium Pru av 1.0101 Food Plant Prunus PRP (Bet v 1 family) 160 1513216 Cherry Prunus avium Pru av 1.0203 Food Plant Prunus PRP (Bet v 1 family) 160 44409496 Cherry Prunus avium Pru av 1.0202 Food Plant Prunus PRP (Bet v 1 family) 160 44409474 Cherry Prunus avium Pru av 1.0201 Food Plant Prunus PRP (Bet v 1 family) 160 44409451 Cherry Prunus avium Unassigned Food Plant Prunus PRP (Bet v 1 family) 159 159162378 Cherry Prunus avium Pru av 3 Food Plant Prunus Pru 3 117 6715520 Cherry Prunus avium Unassigned Food Plant Prunus Pru 3 117 313575726 Cherry Prunus avium Unassigned Food Plant Prunus Pru 3 117 313575728 Cherry Prunus avium Pru av 4 Food Plant Prunus Pru 4 Profilin peach cherry almond 131 4761582 Cherry Prunus avium Pru av 2 Food Plant Prunus Pru av 2 245 1144346 Chicken Gallus gallus Gal d 1 Food Animal Gallus Gal d 1 210 124757 Chicken Gallus gallus Unassigned Food Animal Gallus Gal d 1 210 209979542 Chicken Gallus gallus Gal d 2 Food Animal Gallus Gal d 2 155 63052 Chicken Gallus gallus Gal d 2.0101 Food Animal Gallus Gal d 2 386 129293 Chicken Gallus gallus Gal d 2 Food Animal Gallus Gal d 2 386 808969 Chicken Gallus gallus Gal d 2 Food Animal Gallus Gal d 2 385 15826578 Chicken Gallus gallus Unassigned Food Animal Gallus Gal d 2 385 34811333 Chicken Gallus gallus Gal d 3.0101 Food Animal Gallus Gal d 3 705 757851 Chicken Gallus gallus Gal d 3 Food Animal Gallus Gal d 3 705 1351295 Chicken Gallus gallus Gal d 4 Food Animal Gallus Gal d 4 147 126608 Chicken Gallus gallus Gal d 4 Food Animal Gallus Gal d 4 24 212279 Chicken Gallus gallus Gal d 4.0101 Food Animal Gallus Gal d 4 147 63581 Chicken Gallus gallus Gal d 5 Food Animal Gallus Gal d 5 615 63748 Chicken Gallus gallus Unassigned Food Animal Gallus Gal d 6 YGP42 284 3 Chicken Gallus gallus Unassigned Food Anima Gallus parvalbumin 110 225877920 Chinese mitten crab Eriocheir sinensis Unassigned Food Animal Eriocheir tropomyosin 284 134305330 Chinese razor clam Sinonovacula constricta Unassigned Food Animal Sinonovacula tropomyosin [Song paper] 284 156145810 Chinese white shrimp Fenneropenaeus chinensis Unassigned Food Animal Fenneropenaeus Arginine kinase 53 46486948 Chinese white shrimp Fenneropenaeus chinensis Unassigned Food Animal Fenneropenaeus Arginine kinase 53 46486951 Chinese-date Ziziphus mauritiana Ziz m 1.0101 Food Plant Ziziphus Ziz m 1 330 61225281 Chromium Metals Chub mackerel Scomber japonicus Unassigned Food Animal Scomber Parvalbumin 109 29420793 Chum salmon Oncorhynchus keta Onc k 5.0101 Food Animal Oncorhynchus Onc k 5 193 296040357 Clam Scapharca broughtonii Unassigned Food Animal Scapharca tropomyosin 284 219806592 clam Tresus keenae Unassigned Food Animal Tresus tropomyosin 284 219806600 Clam Venerupis philippinarum Unassigned Food Animal Venerupis tropomyosin 284 219806573 Cobalt chloride Metals Coffee Coffea arabica Cof a 1.0101 Food Plant Coffea Cof a 1 263 296399179 Common Amaranth Amaranthus retroflexus Ama r 2.0101 Aero Plant Amaranthus Ama r 2 Proflin 133 227937304 Common timothy Phleum pratense Phl p 1.0102 Aero Plant Phleum Phl p 1 263 473360 Common timothy Phleum pratense Phl p 1.0101 Aero Plant Phleum Phl p 1 263 3901094 Common timothy Phleum pratense Phl p 1 Aero Plant Phleum Phl p 1 241 28373838 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 1 240 45823012 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 1 262 1582250 Common timothy Phleum pratense Phl p 11 Aero Plant Phleum Phi p 11 143 23452313 Common timothy Phleum pratense Phl p 12.0103 Aero Plant Phleum Phl p 12 131 2415700 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 12 131 110644906 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 12 131 110644908 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 12 131 110644910 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 12 131 110644912 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 12 131 110644914 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 12 131 110644916 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 12 131 110644918 Common timothy Phleum pratense Phl p 12.0102 Aero Plant Phleum Phl p 12 131 2415698 Common timothy Phleum pratense Phl p 12.0101 Aero Plant Phleum Phl p 12 131 453976 Common timothy Phleum pratense Phl p 13 Aero Plant Phleum Phl p 13 394 4826572 Common timothy Phleum pratense Phl p 2 Aero Plant Phleum Phl p 2 122 415896 Common timothy Phleum pratense Phl p 4.0101 Aero Plant Phleum Phl p 4 508 54144332 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 4 500 45108973 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 4 500 45108967 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 4 500 189014266 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 4 500 189014268 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 4 500 189014270 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 4 500 189014272 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 4 500 405944794 Common timothy Phleum pratense Phl p 4.0201 Aero Plant Phleum Phl p 4 508 54144334 Common timothy Phleum pratense Phl p 5.0101 Aero Plant Phleum Phl p 5 312 398830 Common timothy Phleum pratense Phl p 5 Aero Plant Phleum Phl p 5 257 422005 Common timothy Phleum pratense Phl p 5 Aero Plant Phleum Phl p 5 280 481397 Common timothy Phleum pratense Phl p 5 Aero Plant Phleum Phl p 5 24 75139900 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 5 285 1092249 Common timothy Phleum pratense Phl p 5.0202 Aero Plant Phleum Phl p 5 281 1684718 Common timothy Phleum pratense Phl p 5.0104 Aero Plant Phleum Phl p 5 276 1684720 Common timothy Phleum pratense Phl p 5.0102 Aero Plant Phleum Phl p 5 286 2398757 Common timothy Phleum pratense Phl p 5.0105 Aero Plant Phleum Phl p 5 276 3135497 Common timothy Phleum pratense Phl p 5.0106 Aero Plant Phleum Phl p 5 276 3135499 Common timothy Phleum pratense Phl p 5.0107 Aero Plant Phleum Phl p 5 276 3135501 Common timothy Phleum pratense Phl p 5.0108 Aero Plant Phleum Phl p 5 276 3135503 Common timothy Phleum pratense Phl p 5.0103 Aero Plant Phleum Phl p 5 312 3309039 Common timothy Phleum pratense Phl p 5.0203 Aero Plant Phleum Phl p 5 295 3309041 Common timothy Phleum pratense Phl p 5.0206 Aero Plant Phleum Phl p 5 290 3309045 Common timothy Phleum pratense Phl p 5.0207 Aero Plant Phleum Phl p 5 287 3309047 Common timothy Phleum pratense Phl p 5 Aero Plant Phleum Phl p 5 275 13430402 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 5 287 21725606 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 5 287 21725608 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 5 287 21725610 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 5 287 21725612 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 5 287 21725614 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 5 287 21725616 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 5 287 21725618 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 5 287 21725620 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 5 287 21725622 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 5 287 21725624 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 5 287 21725626 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 5 287 21725628 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 5 287 21725630 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 5 287 21725632 Common timothy Phleum pratense Phl p 5 Aero Plant Phleum Phl p 5 102 28948464 Common timothy Phleum pratense Phl p 5.0109 Aero Plant Phleum Phl p 5 284 29500897 Common timothy Phleum pratense Phl p 5.0201 Aero Plant Phleum Phl p 5 284 2398759 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 5 309 345108717 Common timothy Phleum pratense Phl p 6.0102 Aero Plant Phleum Phl p 6 138 3004465 Common timothy Phleum pratense Phl p 6.0101 Aero Plant Phleum Phl p 6 138 3004467 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 6 106 3004469 Common timothy Phleum pratense Unassigned Aero Plant Phleum Phl p 6 111 28374072 Common timothy Phleum pratense Phl p 7.0101 Aero Plant Phleum Polcalin (Phl p 7) 78 3367732 Common timothy Phleum pratense Unassigned Aero Plant Phleum pollen allergen group 3 100 283806867 Corn Zea mays Unassigned Aero Plant Zea group 13 pollen allergen 410 89892725 Corn Zea mays Unassigned Aero Plant Zea group 13 pollen allergen 404 89892727 Corn Zea mays Unassigned Aero Plant Zea group 13 pollen allergen 411 89892729 Corn Zea mays Unassigned Aero Plant Zea pollen specific protein 170 1588669 Corn Zea mays Zea m 1.0101 Aero Plant Zea Zea m 1 beta-expansin 269 28630919 Corn Zea mays Unassigned Aero Plant Zea Zea m 1 beta-expansin 269 28630923 Corn Zea mays Unassigned Aero Plant Zea Zea m 1 beta-expansin 269 14193761 Corn Zea mays Unassigned Aero Plant Zea Zea m 1 beta-expansin 245 114794319 Corn Zea mays Unassigned Aero Plant Zea Zea m 1 isoform 263 89892721 Corn Zea mays Unassigned Aero Plant Zea Zea m 1 isoform 252 89892723 Corn Zea mays Unassigned Aero Plant Zea Zea m 1 isoform 99 105969543 Corn Zea mays Unassigned Aero Plant Zea Zea m 1 isoform 269 105969545 Corn Zea mays Unassigned Aero Plant Zea Zea m 1 isoform 270 115502167 Corn Zea mays Unassigned Aero Plant Zea Zea m 1 isoform 269 115502168 Corn Zea mays Unassigned Aero Plant Zea Zea m 25 thioredoxin 128 66841002 Corn Zea mays Zea m 12.0104 Food Plant Zea Zea m 12 profilin 131 2642324 Corn Zea mays Unassigned Food Plant Zea Zea m 12 profilin 131 110644952 Corn Zea mays Unassigned Food Plant Zea Zea m 12 profilin 131 110644954 Corn Zea mays Unassigned Food Plant Zea Zea m 12 profilin 131 110644956 Corn Zea mays Unassigned Food Plant Zea Zea m 12 profilin 131 110644958 Corn Zea mays Unassigned Food Plant Zea Zea m 12 profilin 131 110644960 Corn Zea mays Unassigned Food Plant Zea Zea m 12 profilin 131 110644962 Corn Zea mays Unassigned Food Plant Zea Zea m 12 profilin 130 110644964 Corn Zea mays Zea m 12.0101 Food Plant Zea Zea m 12 profilin 131 313138 Corn Zea mays Zea m 12.0102 Food Plant Zea Zea m 12 profilin 137 313140 Corn Zea mays Zea m 12.0103 Food Plant Zea Zea m 12 profilin 131 313142 Corn Zea mays Zea m 12.0105 Food Plant Zea Zea m 12 profilin 131 11493677 Corn Zea mays Zea m 14.0101 Food Plant Zea Zea m 14 120 168576 Corn Zea mays Zea m 14.0102 Food Plant Zea Zea m 14 99 168578 Crab Charybdis feriatus Cha f 1.0101 Food Animal Charybdis Cha f 1 264 7024506 Crab Portunus sanguinolentus Unassigned Food Animal Portunus Por p 1.0101 tropomyosin 284 119674937 Crab Portunus trituberculatus Unassigned Food Animal Portunus Por p 1.0101 tropomyosin 284 151505281 Crimson seabream Evynnis japonica Unassigned Food Anima Evynnis parvalbumin 109 327342663 Crimson seabream Evynnis japonica Unassigned Food Anima Evynnis parvalbumin 108 327342661 Crustacean Balanus rostratus Unassigned Food Anima Balanus r tropomyosin 284 125659386 cuttle fish Sepia esculenta Unassigned Food Animal Sepia tropomyosin 284 83715928 Danube crayfish Pontastacus leptodactylus Pon | 4.0101 Food Animal Pontastacus Pon | 4 192 134309 Date palm Phoenix dactylifera Pho d 2 Aero Plant Phoenix Pho d 2 131 21322677 Deep-water cape hake Merluccius paradoxus Unassigned Food Animal Merluccius sp. Parvalbumin Hake 108 308191457 Deep-water cape hake Merluccius paradoxus Unassigned Food Animal Merluccius sp. Parvalbumin Hake 108 308191470 Deep-water cape hake Merluccius paradoxus Unassigned Food Animal Merluccius sp. Parvalbumin Hake 95 308191483 Dilantin Chemical Disk abalone Haliotis discus discus Unassigned Food Animal Haliotis Hal m 1 tropomyosin 284 219806586 Disk abalone Haliotis discus discus Unassigned Food Animal Haliotis paramyosin 860 318609972 Dog Canis familiaris Can f 1.0101 Aero Animal Canis Can f 1 Lipocalin 174 2598974 Dog Canis familiaris Can f 2 Aero Animal Canis Can f 2 Lipocalin 177 29292272 Dog Canis familiaris Can f 2 Aero Animal Canis Can f 2 Lipocalin 179 29292274 Dog Canis familiaris Can f 2.0101 Aero Animal Canis Can f 2 Lipocalin 180 2598976 Dog Canis familiaris Can f 3 Aero Animal Canis Can f 3 Serum albumin 265 633938 Dog Canis familiaris Can f 3 Aero Animal Canis Can f 3 Serum albumin 585 3319897 Dog Canis familiaris Can f 3.0101 Aero Animal Canis Can f 3 Serum albumin 608 22531688 Dog Canis familiaris Can f 4.0101 Aero Animal Canis Can f 4 epithelial 18 kDa 174 262232390 Dog Canis familiaris Can f 5.0101 Aero Animal Canis Can f 5 260 868 Dog Canis familiaris Can f 6.0101 Aero Animal Canis Can f 6 Lipocalin 190 374092884 Domestic guinea pig Cavia porcellus Cav p 1 Aero Animal Cavia Cav p 1 15 32469617 Domestic guinea pig Cavia porcellus Cav p 2.0101 Aero Animal Cavia Cav p 2 170 325910590 Domestic guinea pig Cavia porcellus Cav p 3.0101 Aero Animal Cavia Cav p 3 lipocalin 170 325910592 Dust Mite Tyrophagus putrescentiae Unassigned Aero mite Tyrophagus Tyr p 10 tropomyosin 284 148615631 Dust Mite Tyrophagus putrescentiae Unassigned Aero mite Tyrophagus Tyr p 10 tropomyosin 201 156938915 Dust Mite Tyrophagus putrescentiae Tyr p 10.0101 Aero mite Tyrophagus Tyr p 10 tropomyosin 284 48249227 Dust Mite Tyrophagus putrescentiae Tyr p 13 Aero mite Tyrophagus Tyr p 13 131 51860756 Dust Mite Tyrophagus putrescentiae Unassigned Aero mite Tyrophagus Tyr p 13 130 121296500 Dust Mite Tyrophagus putrescentiae Unassigned Aero mite Tyrophagus Tyr p 13 131 156938917 Dust Mite Tyrophagus putrescentiae Tyr p 2 Aero mite Tyrophagus Tyr p 2 141 2182106 Dust Mite Tyrophagus putrescentiae Tyr p 24.0101 Aero mite Tyrophagus Tyr p 24 Troponin C 153 219815476 Dust Mite Tyrophagus putrescentiae Tyr p 3.0101 Aero mite Tyrophagus Tyr p 3 285 167540622 Dust Mite Tyrophagus putrescentiae Unassigned Aero mite Tyrophagus Tyr p 8 218 452215228 Eastern oyster Crassostrea virginica Unassigned Food Animal Crassostrea Tropomyosin 160 3668408 Egg Food English walnut Juglans regia Jug r 1.0101 Food Plant Juglans Jug r 1 Jug n 1 139 1794252 English walnut Juglans regia Jug r 2.0101 Food Plant Juglans Jug r 2 593 6580762 English walnut Juglans regia Unassigned Food Plant Juglans Jug r 3 119 209484145 English walnut Juglans regia Jug r 4.0101 Food Plant Juglans Jug r 4 seed storage protein 507 56788031 European ash Fraxinus excelsior Unassigned Aero Plant Fraxinus excelsior profilin 134 589912889 European ash Fraxinus excelsior Fra e 1.0201 Aero Plant Fraxinus Fra e 1 146 34978692 European ash Fraxinus excelsior Fra e 1.0102 Aero Plant Fraxinus Fra e 1 145 56122438 European ash Fraxinus excelsior Fra e 1.0101 Aero Plant Fraxinus Fra e 1 145 33327133 European Beech Fagus sylvatica Unassigned Aero Plant Fagus Fag s 1 160 212291472 European Beech Fagus sylvatica Fag s 1 Aero Plant Fagus Fag s 1 160 212291470 European Beech Fagus sylvatica Unassigned Aero Plant Fagus Fag s 1 160 212291474 European chestnut Castanea sativa Cas s 1 Aero Plant Castanea Cas s 1 160 16555781 European chestnut Castanea sativa Unassigned Aero Plant Castanea Cas s 1 159 212291466 European chestnut Castanea sativa Cas s 1.0101 Aero Plant Castanea Cas s 1 159 212291464 European chestnut Castanea sativa Unassigned Aero Plant Castanea Cas s 1 159 212291468 European chestnut Castanea sativa Unassigned Aero Plant Castanea Cas s 5 298 307159110 European chestnut Castanea sativa Cas s 5 Food Plant Castanea Cas s 5 316 1359600 European hake Merluccius merluccius Unassigned Food Animal Merluccius sp. Parvalbumin Hake 108 131116 European hake Merluccius merluccius Unassigned Food Animal Merluccius sp. Parvalbumin Hake 108 308191469 European hazelnut Corylus avellana Cor a 1.0103 Aero Plant Corylus Cor a 1 160 22684 European hazelnut Corylus avellana Cor a 1.0104 Aero Plant Corylus Cor a 1 160 22686 European hazelnut Corylus avellana Cor a 1.0102 Aero Plant Corylus Cor a 1 160 22690 European hazelnut Corylus avellana Cor a 1.0201 Aero Plant Corylus Cor a 1 160 1321731 European hazelnut Corylus avellana Cor a 1.0301 Aero Plant Corylus Cor a 1 160 1321733 European hazelnut Corylus avellana Cor a 2.0101 Aero Plant Corylus Cor a 2 profilins 131 12659206 European hazelnut Corylus avellana Cor a 2.0102 Aero Plant Corylus Cor a 2 profilins 131 12659208 European hazelnut Corylus avellana Cor a 1.0401 Food Plant Corylus Cor a 1 161 5726304 European hazelnut Corylus avellana Cor a 1.0402 Food Plant Corylus Cor a 1 161 11762102 European hazelnut Corylus avellana Cor a 1.0403 Food Plant Corylus Cor a 1 161 11762104 European hazelnut Corylus avellana Cor a 1.0404 Food Plant Corylus Cor a 1 161 11762106 European hazelnut Corylus avellana Cor a 1.0101 Food Plant Corylus Cor a 1 160 22688 European hazelnut Corylus avellana Cor a 11 Food Plant Corylus Cor a 11 448 19338630 European hazelnut Corylus avellana Cor a 12.0101 Food Plant Corylus Cor a 12 159 49617323 European hazelnut Corylus avellana Cor a 13.0101 Food Plant Corylus Cor a 13 Oleosin 140 29170509 European hazelnut Corylus avellana Cor a 14.0101 Food Plant Corylus Cor a 14 2S albumin 147 226437844 European hazelnut Corylus avellana Unassigned Food Plant Corylus Cor a 2 profilins 131 576017879 European hazelnut Corylus avellana Unassigned Food Plant Corylus Cor a 2 profilins 133 576017878 European hazelnut Corylus avellana Unassigned Food Plant Corylus Cor a 2 profilins 133 576017819 European hazelnut Corylus avellana Unassigned Food Plant Corylus Cor a 2 profilins 131 576017779 European hazelnut Corylus avellana Unassigned Food Plant Corylus Cor a 2 profilins 133 576017777 European hazelnut Corylus avellana Unassigned Food Plant Corylus Cor a 2 profilins 133 576017776 European hazelnut Corylus avellana Cor a 8 Food Plant Corylus Cor a 8 115 13507262 European hazelnut Corylus avellana Cor a 9 Food Plant Corylus Cor a 9 515 18479082 European hop hornbeam Ostrya carpinifolia Ost c 1.0101 Aero Plant Ostrya Ost c 1pollen allergen 160 300872535 European hornet Vespa crabro Unassigned Venom or Vespa Vesp c 1 phospholipase 301 313471397 European hornet Vespa crabro Vesp c 5.0101 Venom or Vespa Vesp c 5 202 549184 European hornet Vespa crabro Vesp c 5.0102 Venom or Vespa Vesp c 5 202 549185 European pigeon tick Argas reflexus Arg r 1 Venom or Argas Arg r 1 159 58371884 European pigeon tick Argas reflexus Unassigned Venom or Argas Arg r 1 144 322812205 European rabbit Oryctolagus cuniculus Ory c 3.A.0101 Aero Animal Oryctolagus Ory c 3 93 11993600 European rabbit Oryctolagus cuniculus Ory c 3.B.0101 Aero Animal Oryctolagus Ory c 3 90 11993592 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 51 320545 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 160 534898 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 159 534900 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 160 534910 European white birch Betula pendula Bet v 1.1601 Aero Plant Betula Bet v 1 160 1321714 European white birch Betula pendula Bet v 1.1701 Aero Plant Betula Bet v 1 160 1321716 European white birch Betula pendula Bet v 1.1801 Aero Plant Betula Bet v 1 160 1321718 European white birch Betula pendula Bet v 1.1502 Aero Plant Betula Bet v 1 160 1321720 European white birch Betula pendula Bet v 1.1901 Aero Plant Betula Bet v 1 160 1321722 European white birch Betula pendula Bet v 1.2001 Aero Plant Betula Bet v 1 160 1321724 European white birch Betula pendula Bet v 1.2101 Aero Plant Betula Bet v 1 160 1321726 European white birch Betula pendula Bet v 1.2201 Aero Plant Betula Bet v 1 160 1321728 European white birch Betula pendula Bet v 1m/n Aero Plant Betula Bet v 1 160 1168710 European white birch Betula pendula Bet v 1.0108 Aero Plant Betula Bet v 1 160 1542861 European white birch Betula pendula Bet v 1.0109 Aero Plant Betula Bet v 1 160 1542863 European white birch Betula pendula Bet v 1.0110 Aero Plant Betula Bet v 1 160 1542865 European white birch Betula pendula Bet v 1.0111 Aero Plant Betula Bet v 1 160 1542867 European white birch Betula pendula Bet v 1.0112 Aero Plant Betula Bet v 1 160 1542869 European white birch Betula pendula Bet v 1.0113 Aero Plant Betula Bet v 1 160 1542871 European white birch Betula pendula Bet v 1.0114 Aero Plant Betula Bet v 1 160 1542873 European white birch Betula pendula Bet v 1.2301 Aero Plant Betula Bet v 1 160 2414158 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 160 2564220 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 160 2564222 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 160 2564224 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 160 2564228 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 160 4006928 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 160 4006945 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 160 4006953 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 160 4006955 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 160 4006957 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 160 4006959 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 160 4006961 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 160 4006965 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 160 4006967 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 159 4376216 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 159 4376219 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 159 4376220 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 159 4376221 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 159 4376222 European white birch Betula pendula Bet v 1 b1 Aero Plant Betula Bet v 1 160 4590392 European white birch Betula pendula Bet v 1 b2 Aero Plant Betula Bet v 1 160 4590394 European white birch Betula pendula bet v 1 b3 Aero Plant Betula Bet v 1 160 4590396 European white birch Betula pendula Bet v 1.0701 Aero Plant Betula Bet v 1 160 1168706 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 159 11514622 European white birch Betula pendula Bet v 1x Aero Plant Betula Bet v 1 21 30908931 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 159 38492423 European white birch Betula pendula Unassigned Aero Plant Betula Bet v 1 43 239734 European white birch Betula pendula Unassigned Aero Plant Betula Bet v 1 120 4006963 European white birch Betula pendula Unassigned Aero Plant Betula Bet v 1 120 4006947 European white birch Betula pendula Bet v 1.0203 Aero Plant Betula Bet v 1 160 452742 European white birch Betula pendula Bet v 1 Aero Plant Betula Bet v 1 159 159162097 European white birch Betula pendula Unassigned Aero Plant Betula Bet v 1 159 560188693 European white birch Betula pendula Unassigned Aero Plant Betula Bet v 1 159 550544347 European white birch Betula pendula Unassigned Aero Plant Betula Bet v 1 160 565807648 European white birch Betula pendula Unassigned Aero Plant Betula Bet v 1 159 560188694 European white birch Betula pendula Unassigned Aero Plant Betula Bet v 1 159 560188692 European white birch Betula pendula Bet v 1.0101 Aero Plant Betula Bet v 1 160 17938 European white birch Betula pendula Bet v 1.0102 Aero Plant Betula Bet v 1 160 452732 European white birch Betula pendula Bet v 1.0103 Aero Plant Betula Bet v 1 160 452734 European white birch Betula pendula Bet v 1.0104 Aero Plant Betula Bet v 1 160 452736 European white birch Betula pendula Bet v 1.0106 Aero Plant Betula Bet v 1 160 452740 European white birch Betula pendula Bet v 1.0107 Aero Plant Betula Bet v 1 160 452744 European white birch Betula pendula Bet v 1.0201 Aero Plant Betula Bet v 1 160 450885 European white birch Betula pendula Bet v 1.0202 Aero Plant Betula Bet v 1 160 452730 European white birch Betula pendula Unassigned Aero Plant Betula Bet v 1b 51 320546 European white birch Betula pendula Unassigned Aero Plant Betula Bet v 2 133 157830684 European white birch Betula pendula Bet v 2.0101 Aero Plant Betula Bet v 2 133 166953 European white birch Betula pendula Unassigned Aero Plant Betula Bet v 2 133 576017922 European white birch Betula pendula Bet v 3.0101 Aero Plant Betula Bet v 3 205 488605 European white birch Betula pendula Bet v 4.0101 Aero Plant Betula Bet v 4 85 809536 European white birch Betula pendula Bet v 6.0102 Aero Plant Betula Bet v 6 308 10764491 European white birch Betula pendula Bet v 7 Aero Plant Betula Bet v 7 173 21886603 Fishtail palm Caryota mitis Unassigned Aero Plant Caryota profilin 131 121277849 Flat fish Lepidorhombus whiffiagonis Lep w 1.0101 Food Animal Lepidorhombus Lep w 1 parvalbumin 109 208608078 Formaldehyde Chemical Frog Rana esculenta Ran e 1 Food Animal Rana Ran e 1 110 20796729 Frog Rana esculenta Ran e 2 Food Animal Rana Ran e 2 109 20797081 Frog Rana sp. CH-2001 Unassigned Food Animal Rana Ran e 1 110 20796733 Frog Rana sp. CH-2001 Unassigned Food Animal Rana Ran e 2 109 20797085 Fungicide Chemica Fungus Alternaria alternata Alt a 1.0101 Aero Fungi Alternaria Alt a 1 157 1842045 Fungus Alternaria alternata Unassigned Aero Fungi Alternaria Alt a 1 115 21913174 Fungus Alternaria alternata Alt a 1.0102 Aero Fungi Alternaria Alt a 1 157 45680856 Fungus Alternaria alternata Unassigned Aero Fungi Alternaria Alt a 1 133 390980892 Fungus Alternaria alternata Unassigned Aero Fungi Alternaria Alt a 1 130 508123617 Fungus Alternaria alternata Alt a 10.0101 Aero Fungi Alternaria Alt a 10 ADH 497 76666767 Fungus Alternaria alternata Alt a 12 Aero Fungi Alternaria Alt a 12 Ribosomal BP P1 110 1350779 Fungus Alternaria alternata Alt a 13.0101 Aero Fungi Alternaria Alt a 13 231 74611808 Fungus Alternaria alternata Alt a 3 Aero Fungi Alternaria Alt a 3 HSP 152 14423730 Fungus Alternaria alternata Alt a 4 Aero Fungi Alternaria Alt a 4 thioredoxin 436 85701160 Fungus Alternaria alternata Alt a 5 Aero Fungi Alternaria Alt a 5 ribosomal P2 113 1850540 Fungus Alternaria alternata Unassigned Aero Fungi Alternaria Alt a 5 ribosomal P2 113 1173071 Fungus Alternaria alternata Alt a 6 Aero Fungi Alternaria Alt a 6 enolase 438 14423684 Fungus Alternaria alternata Alt a 7.0101 Aero Fungi Alternaria Alt a 7 flavodoxin 204 1168402 Fungus Alternaria alternata Alt a 8.0101 Aero Fungi Alternaria Alt a 8 (mannitol dehydrogenase) 266 37780013 Fungus Alternaria alternata Unassigned Aero Fungi Alternaria Alt a 8 (mannitol dehydrogenase) 266 118595439 Fungus Alternaria alternata Alt a 14.0101 Aero Fungi Alternaria MnSOD Alt a 14 191 529279957 Fungus Alternaria alternata Unassigned Aero Fungi Alternaria Nuc Transport 2 124 21748153 Fungus Alternaria alternata Unassigned Aero Fungi Alternaria TCTP IgE binding 169 112824341 Fungus Aspergillus flavus Unassigned Aero Fungi Aspergillus Oryzin Asp o 13, fl 13 403 74665726 Fungus Aspergillus fumigatus Asp f 1 Aero Fungi Aspergillus Asp f 1 125 3021324 Fungus Aspergillus fumigatus Asp f 1 Aero Fungi Aspergillus Asp f 1 150 9280360 Fungus Aspergillus fumigatus Unassigned Aero Fungi Aspergillus Asp f 1 176 54039254 Fungus Aspergillus fumigatus Asp f 10 Aero Fungi Aspergillus Asp f 10 395 963013 Fungus Aspergillus fumigatus Asp f 11 Aero Fungi Aspergillus Asp f 11 178 5019414 Fungus Aspergillus fumigatus Asp f 18.0101 Aero Fungi Aspergillus Asp f 18 and Asp n 18 495 2143220 Fungus Aspergillus fumigatus Asp f 2 Aero Fungi Aspergillus Asp f 2 250 664852 Fungus Aspergillus fumigatus Asp f 2 Aero Fungi Aspergillus Asp f 2 310 83300352 Fungus Aspergillus fumigatus Asp f 22 Aero Fungi Aspergillus Asp f 22 438 13925873 Fungus Aspergillus fumigatus Unassigned Aero Fungi Aspergillus Asp f 22 438 83288046 Fungus Aspergillus fumigatus Asp f 23.0101 Aero Fungi Aspergillus Asp f 23 392 21215170 Fungus Rhodotorula mucilaginosa Rho m 1.0101 Aero Fungi Rhodotorula Rho m 1 439 30314940 Fungus Rhodotorula mucilaginosa Rho m 2.0101 Aero Fungi Rhodotorula Rho m 2 342 54654335 Fungus Stachybotrys chartarum Sta 3.0101 Aero Fungi Stachybotrys Sta c 3 144 253970748 Fungus Stemphylium callistephi Unassigned Aero Fungi Stemphylium major allergen alt a1-like 137 49476467 Fungus Stemphylium sp. CID1012 Unassigned Aero Fungi Stemphylium major allergen alt a1-like 137 152060760 Fungus Stemphylium vesicarium Unassigned Aero Fungi Stemphylium major allergen alt a1-like 137 49476465 Fungus Aspergillus fumigatus Unassigned Aero Fungi Aspergillus Asp f 23 392 83305621 Fungus Aspergillus fumigatus Asp f 27.0101 Aero Fungi Aspergillus Asp f 27 163 91680605 Fungus Aspergillus fumigatus Asp f 28.0101 Aero Fungi Aspergillus Asp f 28 108 91680607 Fungus Aspergillus fumigatus Asp f 29.0101 Aero Fungi Aspergillus Asp f 29 110 91680609 Fungus Aspergillus fumigatus Asp f 3 Aero Fungi Aspergillus Asp f 3 168 2769700 Fungus Aspergillus fumigatus Asp f 34.0101 Aero Fungi Aspergillus Asp f 34 185 133920236 Fungus Aspergillus fumigatus Asp f 4 Aero Fungi Aspergillus Asp f 4 286 3005839 Fungus Aspergillus fumigatus Unassigned Aero Fungi Aspergillus Asp f 4 322 83300369 Fungus Aspergillus fumigatus Asp f 5 Aero Fungi Aspergillus Asp f 5 634 3776613 Fungus Aspergillus fumigatus Unassigned Aero Fungi Aspergillus Asp f 5 634 85541646 Fungus Aspergillus fumigatus Asp f 6 Aero Fungi Aspergillus Asp f 6 221 1648970 Fungus Aspergillus fumigatus Unassigned Aero Fungi Aspergillus Asp f 6 210 83305645 Fungus Aspergillus fumigatus Asp f 7 Aero Fungi Aspergillus Asp f 7 270 83300389 Fungus Aspergillus fumigatus Asp f 8 Aero Fungi Aspergillus Asp f 8 111 6686524 Fungus Aspergillus fumigatus Unassigned Aero Fungi Aspergillus Asp f 8 111 83305635 Fungus Aspergillus fumigatus Asp f 9 Aero Fungi Aspergillus Asp f 9 302 2879890 Fungus Aspergillus fumigatus Af293 Unassigned Aero Fungi Aspergillus Asp f 2 304 66849502 Fungus Aspergillus niger Unassigned Aero Fungi Aspergillus Asp f 18 and Asp n 18 533 289172 Fungus Aspergillus niger Asp n 14 Aero Fungi Aspergillus Asp n 14 804 2181180 Fungus Aspergillus niger Asp n 14 Aero Fungi Aspergillus Asp n 14 804 4235093 Fungus Aspergillus oryzae Asp o 21 Aero Fungi Aspergillus Asp o 21 499 94706935 Fungus Aspergillus oryzae Asp o 21.0101 Aero Fungi Aspergillus Asp o 21 499 166531 Fungus Aspergillus oryzae Asp o 13 Aero Fungi Aspergillus Oryzin Asp o 13, fl 13 403 129235 Fungus Cladosporium cladosporioides Cla c 14.0101 Aero Fungi Cladosporium Cla c 14 325 301015198 Fungus Cladosporium cladosporioides Cla c 9.0101 Aero Fungi Cladosporium Cla c 9 Davidiella 388 148361511 Fungus Cochliobolus lunatus Cur | 3.0101 Aero Fungi Cochliobolus (Curvularia) Cur | 3 108 14585755 Fungus Cochliobolus lunatus Cur | 2.01 Aero Fungi Cochliobolus (Curvularia) enolase Cur | 2.01 440 14585753 Fungus Cochliobolus lunatus Cur | 4.0101 Aero Fungi Curvularia Cur | 4 506 193507493 Fungus Davidiella tassiana Cla h 10 Aero Fungi Cladosporium / Davidiella Cla h 10 496 76666769 Fungus Davidiella tassiana Cla h 5.0101 Aero Fungi Cladosporium / Davidiella Cla h 5 111 5777795 Fungus Davidiella tassiana Cla h 6 Aero Fungi Cladosporium / Davidiella Cla h 6 440 467660 Fungus Davidiella tassiana Cla h 6 Aero Fungi Cladosporium / Davidiella Cla h 6 440 6015094 Fungus Davidiella tassiana Cla h 7.0101 Aero Fungi Cladosporium / Davidiella Cla h 7 204 467629 Fungus Davidiella tassiana Cla h 8.0101 Aero Fungi Cladosporium / Davidiella Cla h 8 267 37780015 Fungus Davidiella tassiana Cla h 9.0101 Aero Fungi Cladosporium / Davidiella Cla h 9 vacuolar serine 518 60116876 Fungus Davidiella tassiana Unassigned Aero Fungi Cladosporium / Davidiella Heat shock 70 kDa 643 729764 Fungus Davidiella tassiana Unassigned Aero Fungi Cladosporium / Davidiella Hydrophobin 105 22796153 Fungus Davidiella tassiana Unassigned Aero Fungi Cladosporium / Davidiella putative hydrolase 274 76446100 Fungus Davidiella tassiana Unassigned Aero Fungi Cladosporium / Davidiella Putative nuclear 125 21748151 Fungus Epicoccum nigrum Epi p 1.0101 Aero Fungi Epicoccum Epi p 1 18 24636820 Fungus Fusarium culmorum Unassigned Aero Fungi Fusarium claimed Fus c 3 450 25361513 Fungus Fusarium culmorum Fus c 1 Aero Fungi Fusarium Fus c 1 109 19879657 Fungus Fusarium culmorum Fus c 2 Aero Fungi Fusarium Fus c 2 121 19879659 Fungus Fusarium proliferatum Fus p 4.0101 Aero Fungi Fusarium Fus p 4 323 619498167 Fungus Penicillium brevicompactum Pen b 26.0101 Aero Fungi Penicillium Pen b 26 107 59894749 Fungus Penicillium chrysogenum Pen ch 18.0101 Aero Fungi Penicillium Pen 18 494 7963902 Fungus Penicillium chrysogenum Pen ch 18 Aero Fungi Penicillium Pen 18 494 14215732 Fungus Penicillium chrysogenum Pen ch 13.0101 Aero Fungi Penicillium Pen ch 13 397 6684758 Fungus Penicillium chrysogenum Pen ch 13 Aero Fungi Penicillium Pen ch 13 398 21069093 Fungus Penicillium chrysogenum Pen ch 20 Aero Fungi Penicillium Pen ch 20 117 999009 Fungus Penicillium chrysogenum Pen ch 35.0101 Aero Fungi Penicillium Pen ch 35 324 300679427 Fungus Penicillium citrinum Unassigned Aero Fungi Penicillium Pen 18 457 4588118 Fungus Penicillium citrinum Unassigned Aero Fungi Penicillium Pen 18 358 12005501 Fungus Penicillium citrinum Pen c 19 Aero Fungi Penicillium Pen c 19 503 14423733 Fungus Penicillium citrinum Pen c 22 Aero Fungi Penicillium Pen c 22 438 13991101 Fungus Penicillium citrinum Pen c 24 Aero Fung Penicillium Pen c 24 228 38326693 Fungus Penicillium citrinum Pen c 3 Aero Fungi Penicillium Pen c 3 167 5326864 Fungus Penicillium citrinum Pen c 30.0101 Aero Fungi Penicillium Pen c 30 733 82754305 Fungus Penicillium citrinum Pen c 32.0101 Aero Fungi Penicillium Pen c 32 290 121584258 Fungus Penicillium citrinum Unassigned Aero Fungi Penicillium Pen ch 13 397 4587983 Fungus Penicillium crustosum Pen cr 26.0101 Aero Fungi Penicillium crustosum Pen cr 26 60s P1 107 371537645 Fungus Penicillium oxalicum Pen o 18.0101 Aero Fungi Penicillium Pen 18 503 12005497 Fungus Arthroderma benhamiae Unassigned Contact Trichophyton (Arthroderma) Tri m 4 726 23894232 Fungus Arthroderma benhamiae Unassigned Contact Trichophyton (Arthroderma) Tri r 2 292 23894240 Fungus Arthroderma benhamiae Unassigned Contact Trichophyton (Arthroderma) Tri r 2 404 23894244 Fungus Arthroderma vanbreuseghemii Unassigned Contact Trichophyton (Arthroderma) Tri m 4 726 219687753 Fungus Trichophyton rubrum Tri r 2 Contact Trichophyton (Arthroderma) Tri r 2 412 5813790 Fungus Trichophyton rubrum Tri r 4 Contact Trichophyton tri 4 allergen (Arthroderma) 726 5813788 Fungus Trichophyton schoenleinii Unassigned Contact Trichophyton (Arthroderma) Tri r 2 405 74663809 Fungus Trichophyton schoenleinii Unassigned Contact Trichophyton tri 4 allergen (Arthroderma) 726 23894227 Garlic Food German cockroach Blattella germanica Unassigned Aero Insect Blattella 36 kDa allergen 20 544618 German cockroach Blattella germanica Unassigned Aero Insect Blattella 36 kDa allergen 25 544619 German cockroach Blattella germanica Unassigned Aero Insect Blattella arginine kinase 356 221602737 German cockroach Blattella germanica Bla g 1.0201 Aero Insect Blattella Bla g 1 492 4240395 German cockroach Blattella germanica Bla g 1.0101 Aero Insect Blattella Bla g 1 412 4572592 German cockroach Blattella germanica Bla g 11.0101 Aero Insect Blattella Bla g 11 alpha Amylase 515 85002763 German cockroach Blattella germanica Unassigned Aero Insect Blattella Bla g 2 330 62738637 German cockroach Blattella germanica Unassigned Aero Insect Blattella Bla g 2 352 145105726 German cockroach Blattella germanica Bla g 2.0101 Aero Insect Blattella Bla g 2 352 1176397 German cockroach Blattella germanica Unassigned Aero Insect Blattella Bla g 2 334 315113421 German cockroach Blattella germanica Unassigned Aero Insect Blattella Bla g 3 657 262272875 German cockroach Blattella germanica Bla g 3.0101 Aero Insect Blattella Bla g 3 657 262272877 German cockroach Blattella germanica Bla g 4 Aero Insect Blattella Bla g 4 182 1166573 German cockroach Blattella germanica Unassigned Aero Insect Blattella Bla g 4 182 144952778 German cockroach Blattella germanica Unassigned Aero Insect Blattella Bla g 4 181 212675308 German cockroach Blattella germanica Unassigned Aero Insect Blattella Bla g 4 191 194350815 German cockroach Blattella germanica Unassigned Aero Insect Blattella Bla g 4 190 194350817 German cockroach Blattella germanica Unassigned Aero Insect Blattella Bla g 5 200 144952780 German cockroach Blattella germanica Bla g 5.0101 Aero Insect Blattella Bla g 5 200 2326190 German cockroach Blattella germanica Bla g 6.0101 Aero Insect Blattella Bla g 6 151 82704032 German cockroach Blattella germanica Bla g 6.0201 Aero Insect Blattella Bla g 6 151 82704034 German cockroach Blattella germanica Bla g 6.0301 Aero Insect Blattella Bla g 6 154 82704036 German cockroach Blattella germanica Bla g 7.0101 Aero Insect Blattella Bla g 7 284 8101069 German cockroach Blattella germanica Unassigned Aero Insect Blattella delta GST 216 161137518 Gian Bull ant Myrmecia banksi Myr p 3.0101 Venom or Myrmecia Myr p 3 84 51241753 Giant honeybee Apis dorsata Api d 1.0101 Venom or Apis Api m 1 Api d 1 Api c 1 134 47117012 Giant honeybee Apis dorsata Unassigned Venom or Apis Api m 4 Melittin 26 126955 giant mud crab Scylla serrata Unassigned Food Animal Scylla sp. (mud crab) tropomyosin 284 151505279 Giant ragweed Ambrosia trifida Amb t 5 Aero Plant Ambrosia Amb t 5 Ra5G 73 114091 Giant River Prawn Macrobrachium rosenbergii Mac r 1.0101 Food Animal Macrobrachium rosenbergii shrimp tropomyosin 284 288819271 Giant River Prawn Macrobrachium rosenbergii Unassigned Food Animal Macrobrachium rosenbergii shrimp tropomyosin 284 558698675 Gold gold sodium thiosulfate Metals Gould's razor shell Solen strictus Unassigned Food Animal Solen tropomyosin 284 219806602 Grape Vitis sp. Unassigned Food Plant Vitis Lipid transfer protein P3 91 145559502 Grape Vitis sp. Vit v 1 Food Plant Vitis Vit v 1 LTP 37 462719 Grape Vitis sp. Unassigned Food Plant Vitis Vit v 1 LTP 38 462717 Greasyback shrimp Metapenaeus ensis Met e 1 Food Animal Metapenaeus Met e 1 Tropomyosin 274 607633 green mud crab Scylla paramamosain Unassigned Food Animal Scylla arginine kinase 357 375298903 Hardy Kiwi Actinidia arguta Unassigned Food Plant Actinidia arguta kiwellin 213 441482362 Hardy Kiwi Actinidia arguta Unassigned Food Plant Actinidia arguta kiwellin 213 441482364 Hardy Kiwi Actinidia arguta Unassigned Food Plant Actinidia arguta kiwellin 213 441482366 Honeybee Apis mellifera Api m 1 Venom or Apis Api m 1 Api d 1 Api c 1 167 24418862 Honeybee Apis mellifera Unassigned Venom or Apis Api m 10 icarapin 223 94471622 Honeybee Apis mellifera Api m 10.0101 Venom or Apis Api m 10 icarapin 175 94471624 Honeybee Apis mellifera Api m 2 Venom or Apis Api m 2 382 585279 Honeybee Apis mellifera Unassigned Venom or Apis Api m 3 acid phosphatase 388 208342441 Honeybee Apis mellifera Api m 3.0101 Venom or Apis Api m 3 acid phosphatase 388 74835477 Honeybee Apis mellifera Api m 4.0101 Venom or Apis Api m 4 Melittin 70 5622 Honeybee Apis mellifera Unassigned Venom or Apis Api m 4 Melittin 27 69552 Honeybee Apis mellifera Api m 5.0101 Venom or Apis Api m 5 dipeptidylpeptidase 775 187281543 Honeybee Apis mellifera Unassigned Venom or Apis Api m 6 92 94400907 Honeybee Apis mellifera Unassigned Venom or Apis Api m 6 94 88770352 Honeybee Apis mellifera Api m 11.0101 Venom or Apis mellifera Api m 11 416 Honeybee Apis mellifera Api m 11.0201 Venom or Apis mellifera Api m 11 423 Honeybee Apis mellifera Api m 12.0101 Venom or Apis mellifera Api m 12 1770 29329817 Hornbeam Carpinus betulus Car b 1.0102 Aero Plant Carpinus Car b 1 159 402745 Hornbeam Carpinus betulus Car b 1.0103 Aero Plant Carpinus Car b 1 160 1545875 Hornbeam Carpinus betulus Car b 1.0104 Aero Plant Carpinus Car b 1 160 1545877 Hornbeam Carpinus betulus Car b 1.0105 Aero Plant Carpinus Car b 1 160 1545879 Hornbeam Carpinus betulus Car b 1.0108 Aero Plant Carpinus Car b 1 160 1545893 Hornbeam Carpinus betulus Car b 1.0301 Aero Plant Carpinus Car b 1 161 1545895 Hornbeam Carpinus betulus Car b 1.0302 Aero Plant Carpinus Car b 1 161 1545897 Hornbeam Carpinus betulus Unassigned Aero Plant Carpinus Car b 1 40 239735 Hornbeam Carpinus betulus Car b 1.0113 Aero Plant Carpinus Car b 1 160 167472845 Hornbeam Carpinus betulus Car b 1.0109 Aero Plant Carpinus Car b 1 160 167472837 Hornbeam Carpinus betulus Car b 1.0112 Aero Plant Carpinus Car b 1 160 167472843 Hornbeam Carpinus betulus Car b 1.0111 Aero Plant Carpinus Car b 1 160 167472841 Hornbeam Carpinus betulus Car b 1.0110 Aero Plant Carpinus Car b 1 160 167472839 Hornbeam Carpinus betulus Unassigned Aero Plant Carpinus Car b 1 80 1008578 Hornbeam Carpinus betulus Unassigned Aero Plant Carpinus Car b 1 80 1008579 Hornbeam Carpinus betulus Unassigned Aero Plant Carpinus Car b 1 80 1008580 Hornbeam Carpinus betulus Car b 1.0101 Aero Plant Carpinus Car b 1 159 402743 Hornbeam Carpinus betulus Car b 1.0106 Aero Plant Carpinus Car b 1 160 1545881 Hornbeam Carpinus betulus Car b 1.0107 Aero Plant Carpinus Car b 1 160 1545889 Hornbeam Carpinus betulus Car b 1.0201 Aero Plant Carpinus Car b 1 159 402747 Hornet Vespa magnifica Unassigned Venom or Vespa magnifica Vesp ma 2 hyaluronidase 357 315133295 Hornet Vespa magnifica Unassigned Venom or Vespa magnifica Vesp ma 5 225 319801357 Horse Equus caballus Equ c 1.0101 Aero Animal Equus Equ c 1 187 1575778 Horse Equus caballus Equ c 2.0101 Aero Animal Equus Equ c 2 29 3121755 Horse Equus caballus Equ c 2.0102 Aero Animal Equus Equ c 2 19 3121756 Horse Equus caballus Equ c 3.0101 Aero Animal Equus Equ c 3 607 399672 Horse Equus caballus Equ c4.0101 Aero Animal Equus Equ c 4 and Equ c 5 228 126514234 Horse fly Tabanus yao Tab y 1.0101 Venom or Tabanus Tab y 1 Apyrase 554 323473390 Horse fly Tabanus yao Tab y 2.0101 Venom or Tabanus Tab y 2 Hyaluronidase 349 304273371 Horse fly Tabanus yao Tab y 5.0101 Venom or Tabanus Tab y 5 256 304273369 Horse hair crab Erimacrus isenbeckii Unassigned Food Animal Erimacrus tropomyosin 284 125995169 Horse hair crab Erimacrus isenbeckii Unassigned Food Animal Erimacrus tropomyosin 284 125995171 Hot Peppers Food House dust mite Dermatophagoides farinae Der f 13.0101 Aero Mite Dermatophagoides Der f 13 131 37958167 House dust mite Dermatophagoides farinae Der f 16 Aero Mite Dermatophagoides Der f 16 480 21591547 House dust mite Dermatophagoides farinae Der f 25.0101 Aero Mite Dermatophagoides Der f 25 247 442565872 House dust mite Dermatophagoides farinae Der f 25.0201 Aero Mite Dermatophagoides Der f 25 247 685432812 House dust mite Dermatophagoides farinae Der f 28.0101 Aero Mite Dermatophagoides Der f 28 659 442565876 House dust mite Dermatophagoides farinae Der f 28.0201 Aero Mite Dermatophagoides Der f 28 654 685432788 House dust mite Dermatophagoides farinae Der f 29.0101 Aero Mite Dermatophagoides Der f 29 164 37958141 House dust mite Dermatophagoides farinae Der f 30.0101 Aero Mite Dermatophagoides Der f 30 171 442565878 House dust mite Dermatophagoides farinae Der f 1 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 321 730035 House dust mite Dermatophagoides farinae Der f 1.0101 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 321 27530349 House dust mite Dermatophagoides farinae Der f 1.0102 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 276 76097507 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 321 156106765 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 263 37958161 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 305 387178006 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 303 305387429 House dust mite Dermatophagoides farinae Der f 1.0108 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 321 119633260 House dust mite Dermatophagoides farinae Der f 1.0109 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 321 119633262 House dust mite Dermatophagoides farinae Der f 1.0110 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 321 119633264 House dust mite Dermatophagoides farinae Der f 10.0101 Aero Mite Dermatophagoides Der p 10 / Der f 10 299 1359436 House dust mite Dermatophagoides farinae Der f 11 Aero Mite Dermatophagoides Der p 11 / Der f 11 692 13785807 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides Der p 14 / Der f 14 341 729979 House dust mite Dermatophagoides farinae Der f 14.0101 Aero Mite Dermatophagoides Der p 14 / Der f 14 349 1545803 House dust mite Dermatophagoides farinae Der f 2.0102 Aero Mite Dermatophagoides Der p 2 / Der f 2 146 217306 House dust mite Dermatophagoides farinae Der f 2.0103 Aero Mite Dermatophagoides Der p 2 / Der f 2 138 217308 House dust mite Dermatophagoides farinae Der f 2.0105 Aero Mite Dermatophagoides Der p 2 / Der f 2 129 17978844 House dust mite Dermatophagoides farinae Der f 2.0108 Aero Mite Dermatophagoides Der p 2 / Der f 2 146 55859470 House dust mite Dermatophagoides farinae Der f 2.0107 Aero Mite Dermatophagoides Der p 2 / Der f 2 146 55859468 House dust mite Dermatophagoides farinae Der f 2.0106 Aero Mite Dermatophagoides Der p 2 / Der f 2 146 55859466 House dust mite Dermatophagoides farinae Der f 2.0109 Aero Mite Dermatophagoides Der p 2 / Der f 2 129 76097511 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides Der p 2 / Der f 2 146 256631558 House dust mite Dermatophagoides farinae Der f 2.0112 Aero Mite Dermatophagoides Der p 2 / Der f 2 140 37958157 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides Der p 2 / Der f 2 129 387178018 House dust mite Dermatophagoides farinae Der f 2.0101 Aero Mite Dermatophagoides Der p 2 / Der f 2 138 217304 House dust mite Dermatophagoides farinae Der f 2.0116 Aero Mite Dermatophagoides Der p 2 / Der f 2 146 124696217 House dust mite Dermatophagoides farinae Der f 3 Aero Mite Dermatophagoides Der p 3 / Der f 3 232 1314736 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides Der p 3 / Der f 3 259 163638970 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides Der p 3 / Der f 3 259 218203816 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides Der p 3 / Der f 3 259 218203818 House dust mite Dermatophagoides farinae Der f 3.0101 Aero Mite Dermatophagoides Der p 3 / Der f 3 259 1311457 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides Der p 6 / Der f 6 20 404371 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides Der p 6 / Der f 6 279 218203826 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides Der p 6 / Der f 6 279 218203828 House dust mite Dermatophagoides farinae Der f 6.0101 Aero Mite Dermatophagoides Der p 6 / Der f 6 279 6808530 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides Der p 7 / Der f 7 213 37958165 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides Der p 7 / Der f 7 213 218203832 House dust mite Dermatophagoides farinae Der f 18 Aero Mite Dermatophagoides farinae Der f 18 Der p 18 462 27550039 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides farinae Der f 21 Chew 136 140089314 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides farinae Der f 21 Chew 136 140089316 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides farinae Der f 21 Chew 136 140089320 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides farinae Der f 21 Chew 136 140089322 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides farinae Der f 21 Chew 136 140089324 House dust mite Dermatophagoides farinae Unassigned Aero Mite Dermatophagoides farinae Der f 21 Chew 136 140089326 House dust mite Dermatophagoides farinae Der f 21.0101 Aero Mite Dermatophagoides farinae Der f 21 Chew 136 567768173 House dust mite Dermatophagoides microceras Der m 1.0101 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 30 127205 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der f 30 180 15072346 House dust mite Dermatophagoides pteronyssinus Der p 1 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 222 21725560 House dust mite Dermatophagoides pteronyssinus Der p 1 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 222 21725562 House dust mite Dermatophagoides pteronyssinus Der p 1 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 222 21725564 House dust mite Dermatophagoides pteronyssinus Der p 1 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 222 21725566 House dust mite Dermatophagoides pteronyssinus Der p 1 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 222 21725568 House dust mite Dermatophagoides pteronyssinus Der p 1 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 222 21725570 House dust mite Dermatophagoides pteronyssinus Der p 1 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 222 21725572 House dust mite Dermatophagoides pteronyssinus Der p 1 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 222 21725574 House dust mite Dermatophagoides pteronyssinus Der p 1 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 222 21725576 House dust mite Dermatophagoides pteronyssinus Der p 1 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 222 21725578 House dust mite Dermatophagoides pteronyssinus Der p 1 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 222 21725580 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 216 61608445 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 222 83754033 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 223 157696052 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 222 223365887 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 320 195933901 House dust mite Dermatophagoides pteronyssinus Der p 1.0124 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 302 256095986 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 96 387592 House dust mite Dermatophagoides pteronyssinus Der p 1.0101 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 320 511953 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 304 387178004 House dust mite Dermatophagoides pteronyssinus Der p 1.0113 Aero Mite Dermatophagoides Der p 1 Der f 1 Der m 1 302 76097505 House dust mite Dermatophagoides pteronyssinus Der p 10 Aero Mite Dermatophagoides Der p 10 / Der f 10 284 2353266 House dust mite Dermatophagoides pteronyssinus Der p 10.0101 Aero Mite Dermatophagoides Der p 10 / Der f 10 284 2440053 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der p 10 / Der f 10 281 80553470 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der p 10 / Der f 10 284 208970286 House dust mite Dermatophagoides pteronyssinus Der p 11.0101 Aero Mite Dermatophagoides Der p 11 / Der f 11 875 37778944 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der p 13 131 302035350 House dust mite Dermatophagoides pteronyssinus Der p 14.0101 Aero Mite Dermatophagoides Der p 14 / Der f 14 1662 20385544 House dust mite Dermatophagoides pteronyssinus Der p 2 Aero Mite Dermatophagoides Der p 2 / Der f 2 129 21465915 House dust mite Dermatophagoides pteronyssinus Der p 2 Aero Mite Dermatophagoides Der p 2 / Der f 2 129 21725582 House dust mite Dermatophagoides pteronyssinus Der p 2 Aero Mite Dermatophagoides Der p 2 / Der f 2 129 21725584 House dust mite Dermatophagoides pteronyssinus Der p 2 Aero Mite Dermatophagoides Der p 2 / Der f 2 129 21725586 House dust mite Dermatophagoides pteronyssinus Der p 2 Aero Mite Dermatophagoides Der p 2 / Der f 2 129 21725588 House dust mite Dermatophagoides pteronyssinus Der p 2 Aero Mite Dermatophagoides Der p 2 / Der f 2 129 21725590 House dust mite Dermatophagoides pteronyssinus Der p 2 Aero Mite Dermatophagoides Der p 2 / Der f 2 129 21725592 House dust mite Dermatophagoides pteronyssinus Der p 2 Aero Mite Dermatophagoides Der p 2 / Der f 2 129 21725594 House dust mite Dermatophagoides pteronyssinus Der p 2 Aero Mite Dermatophagoides Der p 2 / Der f 2 129 21725596 House dust mite Dermatophagoides pteronyssinus Der p 2 Aero Mite Dermatophagoides Der p 2 / Der f 2 129 21725600 House dust mite Dermatophagoides pteronyssinus Der p 2 Aero Mite Dermatophagoides Der p 2 / Der f 2 129 21725602 House dust mite Dermatophagoides pteronyssinus Der p 2 Aero Mite Dermatophagoides Der p 2 / Der f 2 129 21725604 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der p 2 / Der f 2 129 76097509 House dust mite Dermatophagoides pteronyssinus Der p 2.0114 Aero Mite Dermatophagoides Der p 2 / Der f 2 146 99644635 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der p 2 / Der f 2 130 110560872 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der p 2 / Der f 2 129 157829757 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der p 2 / Der f 2 145 164415595 House dust mite Dermatophagoides pteronyssinus Der p 2.0101 Aero Mite Dermatophagoides Der p 2 / Der f 2 145 9280543 House dust mite Dermatophagoides pteronyssinus Der p 2.0110 Aero Mite Dermatophagoides Der p 2 / Der f 2 129 256095984 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der p 2 / Der f 2 129 387178014 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der p 2 / Der f 2 129 387178008 House dust mite Dermatophagoides pteronyssinus Der p 21.0101 Aero Mite Dermatophagoides Der p 21 140 85687540 House dust mite Dermatophagoides pteronyssinus Der p 23.0101 Aero Mite Dermatophagoides Der p 23 Peritrophin- like 90 171466145 House dust mite Dermatophagoides pteronyssinus Der p 3 Aero Mite Dermatophagoides Der p 3 / Der f 3 261 511476 House dust mite Dermatophagoides pteronyssinus Der p 4 Aero Mite Dermatophagoides Der p 4 496 5059162 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der p 4 19 1351935 House dust mite Dermatophagoides pteronyssinus Der p 5.0102 Aero Mite Dermatophagoides Der p 5 132 913285 House dust mite Dermatophagoides pteronyssinus Der p 5 Aero Mite Dermatophagoides Der p 5 132 28798085 House dust mite Dermatophagoides pteronyssinus Der p 5.0101 Aero Mite Dermatophagoides Der p 5 148 9072 House dust mite Dermatophagoides pteronyssinus Der p 6 Aero Mite Dermatophagoides Der p 6 / Der f 6 20 1352239 House dust mite Dermatophagoides pteronyssinus Der p 7.0101 Aero Mite Dermatophagoides Der p 7 / Der f 7 215 1045602 House dust mite Dermatophagoides pteronyssinus Der p 7 Aero Mite Dermatophagoides Der p 7 / Der f 7 215 10189811 House dust mite Dermatophagoides pteronyssinus Der f 7.0101 Aero Mite Dermatophagoides Der p 7 / Der f 7 213 1311689 House dust mite Dermatophagoides pteronyssinus Der p 8.0101 Aero Mite Dermatophagoides Der p 8 219 807138 House dust mite Dermatophagoides pteronyssinus Unassigned Aero Mite Dermatophagoides Der p 8 219 60920878 House dust mite Dermatophagoides pteronyssinus Der p 18.0101 Aero Mite Dermatophagoides farinae Der f 18 Der p 18 462 67975085 House dust mite Dermatophagoides siboney Unassigned Aero Mite Dermatophagoides Der p 2 / Der f 2 146 86450747 House dust mite Euroglyphus maynei Eur m 1.0101 Aero Mite Euroglyphus Eur m 1 321 3941388 House dust mite Euroglyphus maynei Unassigned Aero Mite Euroglyphus Eur m 1 327 3941390 House dust mite Euroglyphus maynei Eur m 2.0102 Aero Mite Euroglyphus Eur m 2 135 3941386 House dust mite Euroglyphus maynei Eur m 2.0101 Aero Mite Euroglyphus Eur m 2 145 3941384 Indian honeybee Apis cerana Unassigned Venom or Apis Api m 1 Api d 1 Api c 1 134 7435005 Indian honeybee Apis cerana cerana Api c 1.0101 Venom or Apis Api m 1 Api d 1 Api c 1 134 12958583 Indian meal moth Plodia interpunctella Plo i 1.0101 Aero Plant Plodia Plo i 1 Arginine kinase 355 15886861 Indian meal moth Plodia interpunctella Plo i 2.0101 Aero Plant Plodia Plo i 2 thioredoxin 106 308193268 Intravenous contrast dye Chemical Japanese cedar Cryptomeria japonica Unassigned Aero Plant Cryptomeria class IV chitinase 281 56550550 Japanese cedar Cryptomeria japonica Cry j 1.0102 Aero Plant Cryptomeria Cry j 1 374 493634 Japanese cedar Cryptomeria japonica Cry j 1.0101 Aero Plant Cryptomeria Cry j 1 374 493632 Japanese cedar Cryptomeria japonica Cry j 1.0103 Aero Plant Cryptomeria Cry j 1 374 516728 Japanese cedar Cryptomeria japonica Cry j 2 Aero Plant Cryptomeria Cry j 2 514 1171004 Japanese cedar Cryptomeria japonica Cry j 2 Aero Plant Cryptomeria Cry j 2 514 24898904 Japanese cedar Cryptomeria japonica Cry j 2 Aero Plant Cryptomeria Cry j 2 514 24898906 Japanese cedar Cryptomeria japonica Cry j 2 Aero Plant Cryptomeria Cry j 2 514 24898908 Japanese cedar Cryptomeria japonica Unassigned Aero Plant Cryptomeria Cry j 2 514 114841607 Japanese cedar Cryptomeria japonica Unassigned Aero Plant Cryptomeria Cry j 2 514 114841617 Japanese cedar Cryptomeria japonica Unassigned Aero Plant Cryptomeria Cry j 2 514 114841629 Japanese cedar Cryptomeria japonica Unassigned Aero Plant Cryptomeria Cry j 2 514 114841635 Japanese cedar Cryptomeria japonica Unassigned Aero Plant Cryptomeria Cry j 2 514 114841641 Japanese cedar Cryptomeria japonica Unassigned Aero Plant Cryptomeria Cry j 2 514 114841653 Japanese cedar Cryptomeria japonica Unassigned Aero Plant Cryptomeria Cry j 2 514 114841657 Japanese cedar Cryptomeria japonica Unassigned Aero Plant Cryptomeria Cry j 2 514 114841663 Japanese cedar Cryptomeria japonica Unassigned Aero Plant Cryptomeria Cry j 2 514 114841665 Japanese cedar Cryptomeria japonica Cry j 2.0101 Aero Plant Cryptomeria Cry j 2 514 506858 Japanese cedar Cryptomeria japonica Unassigned Aero Plant Cryptomeria Cry j 2 65 123299282 Japanese cedar Cryptomeria japonica Unassigned Aero Plant Cryptomeria Isoflavone reductase-like protein 306 19847822 Japanese cedar Cryptomeria japonica Unassigned Aero Plant Cryptomeria pollen allergen CJP-8 165 291621332 Japanese cedar Cryptomeria japonica Unassigned Aero Plant Cryptomeria pollen allergen CPA63 472 293329689 Japanese cedar Cryptomeria japonica Unassigned Aero Plant Cryptomeria thaumatin like Cry j 3.8 225 139002766 Japanese cypress Chamaecyparis obtusa Cha o 1.0101 Aero Plant Chamaecyparis Cha o 1 375 1514943 Japanese cypress Chamaecyparis obtusa Unassigned Aero Plant Chamaecyparis Cha o 2 514 47606004 Japanese cypress Chamaecyparis obtusa Unassigned Aero Plant Chamaecyparis Cha o 2 419 114841683 Japanese flying squid Todarodes pacificus Unassigned Food Animal Todarodes Tod p 1 284 83715932 Japanese hop Humulus japonicus Hum j 1 Aero Plant Humulus Humj1 155 33113263 Japanese hop Humulus scandens Unassigned Aero Plant Humulus profilin-like protein 131 34851176 Japanese hop Humulus scandens Unassigned Aero Plant Humulus profilin-like protein 131 34851174 Japanese horse mackerel Trachurus japonicus Unassigned Food Animal Trachurus parvalbumin 107 77799800 Japanese turban shell Batillus cornutus Unassigned Food Animal Batillus Tur c1 284 219806588 Japanese white birch Betula platyphylla Unassigned Aero Plant Betula Bet v 1 160 12583681 Japanese white birch Betula platyphylla Unassigned Aero Plant Betula Bet v 1 160 12583683 Japanese white birch Betula platyphylla Unassigned Aero Plant Betula Bet v 1 160 12583685 Johnson grass Sorghum halepense Sor h 1.0101 Aero Plant Sorghum Sor h 1 266 674275729 Johnson grass Sorghum halepense Sor h 1.0201 Aero Plant Sorghum Sor h 1 266 674275731 Johnson grass Sorghum halepense Sor h 13.0101 Aero Plant Sorghum Sor h 13 422 674275737 Johnson grass Sorghum halepense Sor h 13.0201 Aero Plant Sorghum Sor h 13 410 674275739 Jumper ant Myrmecia pilosula Unassigned Venom or Myrmecia Myr p 1 112 1911819 Jumper ant Myrmecia pilosula Myr p 1.0101 Venom or Myrmecia Myr p 1 112 312284 Jumper ant Myrmecia pilosula Myr p 2 Venom or Myrmecia Myr p 2 75 1587177 Jumper ant Myrmecia pilosula Myr p 2.0101 Venom or Myrmecia Myr p 2 75 1438761 Juniper Juniperus oxycedrus Unassigned Aero Plant Juniperus Jun a/v 1 367 15139849 Juniper Juniperus oxycedrus Jun o 4 Aero Plant Juniperus Jun o 4 165 5391446 Kamchatka crab Paralithodes camtschaticus Unassigned Food Animal Paralithodes tropomyosin 284 125995163 Kamchatka crab Paralithodes camtschaticus Unassigned Food Animal Paralithodes tropomyosin 284 125995165 Kentucky bluegrass Poa pratensis Poa p 5 Aero Plant Poa Poa p 5 303 11991227 Kentucky bluegrass Poa pratensis Unassigned Aero Plant Poa Poa p 9 373 113560 Kentucky bluegrass Poa pratensis Unassigned Aero Plant Poa Poa p 9 307 113562 Kentucky bluegrass Poa pratensis Poa p 1 Aero Plant Poa Poa p 1 20 280414 Kentucky bluegrass Poa pratensis Poa p 1 Aero Plant Poa Poa p 1 26 320620 Kentucky bluegrass Poa pratensis Poa p 1.0101 Aero Plant Poa Poa p 1 263 4090265 Kentucky bluegrass Poa pratensis Unassigned Aero Plant Poa Poa p 9 131 539056 Kentucky bluegrass Poa pratensis Unassigned Aero Plant Poa Poa p 9 333 113561 Kidney bean Phaseolus vulgaris Pha v 3.0101 Aero Plant Phaseolus Pha v 3 115 289064177 Kidney bean Phaseolus vulgaris Pha v 3.0201 Aero Plant Phaseolus Pha v 3 118 289064179 Kiwi Actinidia chinensis Unassigned Food Plant Actinidia Act c 1 Act d 1 Actinidin 380 190358935 Kiwi Actinidia chinensis Act c 1 Food Plant Actinidia Act c 10 LTP 15 378548410 Kiwi Actinidia chinensis Act c 5.0102 Food Plant Actinidia Act c 5 kiwellin 213 441482354 Kiwi Actinidia chinensis Act c 8.0101 Food Plant Actinidia Act c 8 Act d 8 PR-10 159 281552896 Kiwi Actinidia chinensis Unassigned Food Plant Actinidia Act d 2 thaumatin like protein 20 68064399 Kiwi Actinidia chinensis Unassigned Food Plant Actinidia Act d 2 thaumatin like protein 225 441482370 Kiwi Actinidia deliciosa Act d 1 Food Plant Actinidia Act c 1 Act d 1 Actinidin 380 15984 Kiwi Actinidia deliciosa Unassigned Food Plant Actinidia Act c 1 Act d 1 Actinidin 380 166317 Kiwi Actinidia deliciosa Unassigned Food Plant Actinidia Act c 1 Act d 1 Actinidin 380 193806686 Kiwi Actinidia deliciosa Act d 8.0101 Food Plant Actinidia Act c 8 Act d 8 PR-10 157 281552898 Kiwi Actinidia deliciosa Act d 10.0201 Food Plant Actinidia Act d 10 LTP 92 378548411 Kiwi Actinidia deliciosa Act d 10.0101 Food Plant Actinidia Act d 10 LTP 92 378405189 Kiwi Actinidia deliciosa Act d 11 Food Plant Actinidia Act d 11 Kirola MLP 150 332319679 Kiwi Actinidia deliciosa Act d 2.0101 Food Plant Actinidia Act d 2 thaumatin like protein 225 71057064 Kiwi Actinidia deliciosa Unassigned Food Plant Actinidia Act d 2 thaumatin like protein 201 146737976 Kiwi Actinidia deliciosa Act d 4.0101 Food Plant Actinidia Act d 4 Phytocystatin 116 40807635 Kiwi Actinidia deliciosa Act d 5.0101 Food Plant Actinidia Act d 5 kiwellin 189 85701136 Kiwi Actinidia deliciosa Unassigned Food Plant Actinidia Act d 5 kiwellin 213 441482346 Kiwi Actinidia deliciosa Unassigned Food Plant Actinidia Act d 5 kiwellin 213 441482348 Kiwi Actinidia deliciosa Unassigned Food Plant Actinidia Act d 5 kiwellin 213 441482350 Kiwi Actinidia deliciosa Unassigned Food Plant Actinidia Act d 5 kiwellin 213 441482352 Kiwi Actinidia deliciosa Act d 7.0101 Food Plant Actinidia Act d 7 321 160419153 Krill Euphausia superba Unassigned Food Animal Euphausia 284 156712752 Kuruma Shrimp Marsupenaeus japonicus Unassigned Food Animal Marsupenaeus tropomyosin 284 125995159 Latex Hev b1, Hev b3, Hev b5, Hev b 6.02 Lemon Citrus limon Cit | 3.0101 Food Plant Citrus LTP Cit s 3/Cit | 3 20 52783176 Lentil Lens culinaris Len c 3.0101 Food Plant Lens Len c 3 118 60735410 Lentil Lens culinaris Len c 1.0101 Food Plant Lens Len c 1 418 29539109 Lentil Lens culinaris Len c 1.0102 Food Plant Lens Len c 1 415 29539111 Lesser banded hornet Vespa affinis Unassigned Food Animal Vespa affinis Phospholipase A1 334 576011175 Lesser banded hornet Vespa affinis Unassigned Food Animal Vespa affinis Phospholipase A1 334 576011171 Lilac Syringa vulgaris Syr v 3.0101 Aero Plant Syringa Syr v 3 81 14423847 Lilac Syringa vulgaris Syr v 1.0101 Aero Plant Syringa Syr v I 145 631911 Lilac Syringa vulgaris Syr v 1.0102 Aero Plant Syringa Syr v I 145 631912 Lilac Syringa vulgaris Syr v 1.0103 Aero Plant Syringa Syr v I 145 631913 Lobster Panulirus stimpsoni Pan s 1.0101 Food Animal Panulirus Pan s 1 274 3080761 Local anesthetics Chemica London plane tree Platanus x acerifolia Pla a 1 Aero Plant Platanus Pla a 1 179 26190140 London plane tree Platanus x acerifolia Pla a 2 Aero Plant Platanus Pla a 2 377 49523394 Lychee nut Litchi chinensis Lit c 1 Aero Plant Litchi Lit c 1 131 15809696 Lychee nut Litchi chinensis Unassigned Aero Plant Litchi Lit c 1 131 83317152 Madagascar periwinkle Catharanthus roseus Cat r 1.0101 Aero Plant Catharanthus cyclophilin 172 1220142 Mantis Shrimp Oratosquilla oratoria Unassigned Food Animal Oratosquilla tropomyosin 284 162286975 Mediterranean Cypress Cupressus sempervirens Cup s 1.0101 Aero Plant Cupressus Cup a 1/Cup s 1 367 8101711 Mediterranean Cypress Cupressus sempervirens Cup s 1.0102 Aero Plant Cupressus Cup a 1/Cup s 1 367 8101713 Mediterranean Cypress Cupressus sempervirens Cups 1.0103 Aero Plant Cupressus Cup a 1/Cup s 1 367 8101715 Mediterranean Cypress Cupressus sempervirens Cup s 1.0104 Aero Plant Cupressus Cup a 1/Cup s 1 367 8101717 Mediterranean Cypress Cupressus sempervirens Cup s 1.0105 Aero Plant Cupressus Cup a 1/Cup s 1 367 8101719 Mediterranean Cypress Cupressus sempervirens Cup s 3.0102 Aero Plant Cupressus Cup s 3 225 38456228 Mediterranean Cypress Cupressus sempervirens Cup s 3.0101 Aero Plant Cupressus Cup s 3 225 38456226 Midge Chironomus kiiensis Chi k 10 Aero Insect Chironomus Chi k 10 285 7321108 Midge Chironomus thummi Chi t 3.0501 Aero Insect Chironomus Chi t 3 160 156585 Midge Chironomus thummi thummi Chi t 1.01 Aero Insect Chironomus Chi t 1 151 121219 Midge Chironomus thummi thummi Chi t 1.02 Aero Insect Chironomus Chi t 1 151 121227 Midge Chironomus thummi thummi Chi t 2.0101 Aero Insect Chironomus Chi t 2 158 2506460 Midge Chironomus thummi thummi Chi t 3.0601 Aero Insect Chironomus Chi t 3 161 56405052 Midge Chironomus thummi thummi Chi t 3.0901 Aero Insect Chironomus Chi t 3 151 121237 Midge Chironomus thummi thummi Chi t 3.0701 Aero Insect Chironomus Chi t 3 161 56405054 Midge Chironomus thummi thummi Chi t 3.0702 Aero Insect Chironomus Chi t 3 161 121248 Midge Chironomus thummi thummi Chi t 3.0801 Aero Insect Chironomus Chi t 3 162 121249 Midge Chironomus thummi thummi Chi t 3.0301 Aero Insect Chironomus Chi t 3 161 56405306 Midge Chironomus thummi thummi Chi t 3.0101 Aero Insect Chironomus Chi t 3 160 1707908 Midge Chironomus thummi thummi Chi t 3.0401 Aero Insect Chironomus Chi t 3 161 1707911 Midge Chironomus thummi thummi Chi t 3.0201 Aero Insect Chironomus Chi t 3 162 2506461 Midge Chironomus thummi thummi Chi t 4 Aero Insect Chironomus Chi t 4 151 121256 Midge Chironomus thummi thummi Chi t 7 Aero Insect Chironomus Chi t 7 161 121244 Midge Chironomus thummi thummi Chi t 9 Aero Insect Chironomus Chi t 9 151 121259 Milk alpha S1-casein Food Mite Acarus siro Unassigned Aero Mite Acarus Aca s 4 517 118638278 Mite Acarus siro Aca s 13 Aero Mite Acarus Aca s 13 131 118638268 Mite Blomia tropicalis Blot 1 Aero Mite Blomia Blo t 1.01 221 14276828 Mite Blomia tropicalis Unassigned Aero Mite Blomia Blo t 1.02 333 33667928 Mite Blomia tropicalis Unassigned Aero Mite Blomia Blo t 1.02 333 2 Mite Blomia tropicalis Blo t 10.0101 Aero Mite Blomia Blo t 10 284 156938889 Mite Blomia tropicalis Blo t 11 Aero Mite Blomia Blo t 11 875 21954740 Mite Blomia tropicalis Blo t 12 Aero Mite Blomia Blo t 12 144 902012 Mite Blomia tropicalis Blo t 13 Aero Mite Blomia Blo t 13.01 130 1377859 Mite Blomia tropicalis Blo t 21.0101 Aero Mite Blomia Blo t 21 129 60679570 Mite Blomia tropicalis Unassigned Aero Mite Blomia Blo t 21 129 111120432 Mite Blomia tropicalis Unassigned Aero Mite Blomia Blo t 21 129 111494253 Mite Blomia tropicalis Unassigned Aero Mite Blomia Blo t 21 129 111120424 Mite Blomia tropicalis Unassigned Aero Mite Blomia Blo t 21 129 111120428 Mite Blomia tropicalis Blo t 3.0101 Aero Mite Blomia Blo t 3 266 25989482 Mite Blomia tropicalis Unassigned Aero Mite Blomia Blo t 3 266 33667930 Mite Blomia tropicalis Unassigned Aero Mite Blomia Blo t 4 alpha amylase 506 33667932 Mite Blomia tropicalis Blo t 5 Aero Mite Blomia Blo t 5 134 4204917 Mite Blomia tropicalis Unassigned Aero Mite Blomia Blo t 5 134 111120436 Mite Blomia tropicalis Unassigned Aero Mite Blomia Blo t 5 134 111120450 Mite Blomia tropicalis Unassigned Aero Mite Blomia Blo t 5 119 160285626 Mite Blomia tropicalis Unassigned Aero Mite Blomia Blo t 7 non_iuis allergen 192 33667936 Mite Blomia tropicalis Unassigned Aero Mite Blomia Blo t 8 236 37958149 Mite Blomia tropicalis Blo t 8.0101 Aero Mite Blomia Blo t 8 236 256665455 Mite Suidasia medanensis Unassigned Aero mite Suidasia putative Sui m 2 141 45738062 Mollusc Fulvia mutica Unassigned Food Animal Fulvia tropomyosin 284 219806596 Mollusc Pseudocardium sachalinensis Unassigned Food Animal Pseudocardium tropomyosin 284 219806598 Mountain cedar Juniperus ashei Jun a 2 Aero Plant Juniperus Jun a 2 507 9955725 Mountain cedar Juniperus ashei Jun a 3.0101 Aero Plant Juniperus Jun a 3 225 9087177 Mountain cedar Juniperus ashei Jun a 1.010101 Aero Plant Juniperus Jun a/v 1 367 4138877 Mouse Mus musculus Mus m 1 Aero Animal Mus Mus m 1 180 20178291 Mouse Mus musculus Mus m 1.0101 Aero Animal Mus Mus m 1 180 295910 Mouse Mus musculus domesticus Mus m 1.0102 Aero Animal Mus Mus m 1 180 199881 Mozambique tilapia Oreochromis mossambicus Ore m 4.0101 Food Anima Oreochromis Ore m 4 tropomyosin 284 410060781 Mugwort Artemisia vulgaris Art v 1 Aero Plant Artemisia Art v 1 132 27818335 Mugwort Artemisia vulgaris Art v 2.0101 Aero Plant Artemisia Art v 2 162 148887203 Mugwort Artemisia vulgaris Art v 3.0101 Aero Plant Artemisia Art v 3 37 73621307 Mugwort Artemisia vulgaris Art v 3.0201 Aero Plant Artemisia Art v 3 114 189544578 Mugwort Artemisia vulgaris Art v 3.0202 Aero Plant Artemisia Art v 3 116 189544584 Mugwort Artemisia vulgaris Art v 3.0301 Aero Plant Artemisia Art v 3 117 189544590 Mugwort Artemisia vulgaris Unassigned Aero Plant Artemisia Art v 3 117 189544595 Mugwort Artemisia vulgaris Art v 4.0101 Aero Plant Artemisia Art v 4 133 25955969 Mugwort Artemisia vulgaris Art v 4.0201 Aero Plant Artemisia Art v 4 133 25955971 Mugwort Artemisia vulgaris Art v 6.0101 Aero Plant Artemisia Art v 6 pectate lyase 396 62530263 Mugwort Artemisia vulgaris Art v 5.0101 Aero Plant Artemisia mugwort Art v 5 82 62530265 Mulberry Morus bombycis Unassigned Food Plant Morus winter accumulating protein 157 54311115 Mulberry Morus bombycis Unassigned Food Plant Morus winter accumulating protein 157 54311119 mung bean Vigna radiata Vig r 1.0101 Food Plant Vigna Vig r 1 PR 10 155 60418924 mung bean Vigna radiata Vig r 2.0101 Food Plant Vigna Vig r 2 453 108743976 mung bean Vigna radiata Vig r 2.0201 Food Plant Vigna Vig r 2 454 158251953 mung bean Vigna radiata Vig r 6.0101 Food Plant Vigna Vig r 6 Cytokinin-specific binding protein 155 4190976 mung bean Vigna radiata var. radiata Vig r 4.0101 Food Plant Vigna Vig r 4 272 1000708 Mushroom Schizophyllum commune H4-8 Sch c 1.0101 Gliadin Schizophyllum Sch c 1 576 302681819 Muskmelon Cucumis melo Cuc m 1 Aero Plant Cucumis Cuc m 1 731 807698 Muskmelon Cucumis melo Unassigned Aero Plant Cucumis Cuc m 2 131 31559374 Muskmelon Cucumis melo Cuc m 2 Aero Plant Cucumis Cuc m 2 131 58263793 Muskmelon Cucumis melo Cuc m 3.0101 Aero Plant Cucumis Cuc m 3 41 46396595 Muskmelon Cucumis melo var. inodorus Unassigned Food Plant Cucumis Cuc m 3 151 171464770 Mustard Brassica juncea Bra j 1 Food Plant Brassica Bra j 1 2S albumin 129 32363444 Narrow-leaved plantain Plantago lanceolata Pla | 1.0101 Aero Plant Plantago Pla | 1 131 14422359 Narrow-leaved plantain Plantago lanceolata Pla | 1.0102 Aero Plant Plantago Pla | 1 131 14422361 Narrow-leaved plantain Plantago lanceolata Pla | 1.0103 Aero Plant Plantago Pla | 1 131 14422363 Narrow-leaved plantain Plantago lanceolata Unassigned Aero Plant Plantago Pla | 1 65 29163773 Navel orange Citrus sinensis Cit s 1.0101 Food Plant Citrus Cit s 1 25 52782810 Navel orange Citrus sinensis Cit s 2.0101 Food Plant Citrus Cit s 2 131 56000996 Navel orange Citrus sinensis Unassigned Food Plant Citrus LTP Cit s 3/Cit | 3 20 52783177 Navel orange Citrus sinensis Cit s 3 Food Plant Citrus LTP Cit s 3/Cit | 3 91 50199132 Netted muskmelon Cucumis melo var. reticulatus Unassigned Food Plant Cucumis Cuc m 2 131 57021110 Nickel nickel sulfate hexahydrate Metals Noble scallop Mimachlamys nobilis Unassigned Food Animal Mimachlamys Tropomyosin 284 9954253 Non-steroidal anti-inflammatoir Chemical North Pacific hake Merluccius productus Unassigned Food Anima Merluccius sp. Parvalbumin Hake 108 308191459 North Pacific hake Merluccius productus Unassigned Food Animal Merluccius sp. Parvalbumin Hake 108 308191472 North Pacific Krill Euphausia pacifica Unassigned Food Animal Euphausia 284 156712754 Oak Quercus alba Que a 1.0201 Aero Plant Quercus Que a 1 159 167472847 Oak Quercus alba Que a 1.0401 Aero Plant Quercus Que a 1 160 167472851 Oak Quercus alba Que a 1.0301 Aero Plant Quercus Que a 1 160 167472849 ocean perch (red fish) Sebastes marinus Seb m 1.0101 Food Animal Sebastes Seb m 1 109 242253959 ocean perch (red fish) Sebastes marinus Seb m 1.0201 Food Animal Sebastes Seb m 1 110 242253961 Octopus Amphioctopus fangsiao Unassigned Food Animal Amphioctopus arginine kinase 348 340742817 Octopus Octopus vulgaris Unassigned Food Animal Octopus tropomyosin 284 83715936 Olive tree Olea europaea Ole e 1 Aero Plant Olea Ole e 1 145 14424429 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 137 1362128 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 136 1362129 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 136 1362130 Olive tree Olea europaea Ole e 1.0104 Aero Plant Olea Ole e 1 145 1362131 Olive tree Olea europaea Ole e 1 Aero Plant Olea Ole e 1 137 1362132 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 136 1362133 Olive tree Olea europaea Ole e 1.0103 Aero Plant Olea Ole e 1 145 1362136 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 136 1362137 Olive tree Olea europaea Ole e 1.0105 Aero Plant Olea Ole e 1 146 2465127 Olive tree Olea europaea Ole e 1.0106 Aero Plant Olea Ole e 1 146 2465129 Olive tree Olea europaea Ole e 1.0107 Aero Plant Olea Ole e 1 146 2465131 Olive tree Olea europaea Ole e 1.0101 Aero Plant Olea Ole e 1 130 13195753 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 134 37724597 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 135 37724593 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 132 37548753 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 131 33329758 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 132 33329756 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 132 33329754 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 131 33329752 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 131 33329750 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 129 33329748 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 131 33329744 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 132 33329738 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 132 33329732 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 132 33325115 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 140 145313982 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 140 145313984 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 140 145313988 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 140 145313990 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 1 140 145313992 Olive tree Olea europaea Ole e 10 Aero Plant Olea Ole e 10 123 29465664 Olive tree Olea europaea Ole e 11.0102 Aero Plant Olea Ole e 11.0101 and 0102 364 68270856 Olive tree Olea europaea Ole e 11.0101 Aero Plant Olea Ole e 11.0101 and 0102 364 269996495 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 13 226 449061783 Olive tree Olea europaea Ole e 2 Aero Plant Olea Ole e 2 134 3914427 Olive tree Olea europaea Ole e 2 Aero Plant Olea Ole e 2 134 3914428 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 2 131 576017874 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 2 131 576017774 Olive tree Olea europaea Ole e 2.0101 Aero Plant Olea Ole e 2 134 2465133 Olive tree Olea europaea Ole e 3.0101 Aero Plant Olea Ole e 3 84 3337403 Olive tree Olea europaea Ole e 3 Aero Plant Olea Ole e 3 52 37725377 Olive tree Olea europaea Ole e 5.0101 Aero Plant Olea Ole e 5 30 122064581 Olive tree Olea europaea Ole e 5 Aero Plant Olea Ole e 5 152 39840779 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 145313972 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160347106 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 144 160347108 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160347112 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160347120 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160347122 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160347124 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160347126 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160347130 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160347134 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160347138 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160962543 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160962547 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160962557 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160962569 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160962577 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160962583 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 144 160962587 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160962591 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160962597 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160962611 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 5 152 160962613 Olive tree Olea europaea Ole e 6.0101 Aero Plant Olea Ole e 6 50 2276458 Olive tree Olea europaea Ole e 7 Aero Plant Olea Ole e 7 21 22002032 Olive tree Olea europaea Ole e 8 Aero Plant Olea Ole e 8 171 6901654 Olive tree Olea europaea Ole e 8.0101 Aero Plant Olea Ole e 8 171 6901652 Olive tree Olea europaea Ole e 9 Aero Plant Olea Ole e 9 460 14279169 Olive tree Olea europaea Unassigned Aero Plant Olea Ole e 9 101 166235350 Orchard grass Dactylis glomerata Dac g 1 Aero Plant Dactylis Dac g 1 264 18093991 Orchard grass Dactylis glomerata Dac g 1.0101 Aero Plant Dactylis Dac g 1 240 33149333 Orchard grass Dactylis glomerata Dac g 2 Aero Plant Dactylis Dac g 2 196 1093120 Orchard grass Dactylis glomerata Dac g 2 Aero Plant Dactylis Dac g 2 122 4007040 Orchard grass Dactylis glomerata Dac g 3 Aero Plant Dactylis Dac g 3 96 1825459 Orchard grass Dactylis glomerata Dac g 4.0101 Aero Plant Dactylis Dac g 4 55 32363463 Orchard grass Dactylis glomerata Dac g 5 Aero Plant Dactylis Dac g 5 290 14423124 Orchard grass Dactylis glomerata Dac g 5 Aero Plant Dactylis Dac g 5 265 18093971 Oriental plane Platanus orientalis Pla or 1.0101 Aero Plant Platanus Pla or 1 170 162949336 Oriental plane Platanus orientalis Pla or 2.0101 Aero Plant Platanus Pla or 2 378 162949338 Papaya Carica papaya Unassigned Food Plant Carica Car p 1 345 129614 Paper wasp Polistes annularis Pol a 5.0101 Food Plant Polistes Pol 5 209 160780 Paper wasp Polistes annularis Pol a 1.0101 Food Plant Polistes Pol a 1 Pol d 1 301 5815249 Paper wasp Polistes annularis Pol a 2.0101 Food Plant Polistes Pol a 2 367 5815251 Paper wasp Polistes dominulus Pol d 5 Food Plant Polistes Pol 5 227 51093377 Paper wasp Polistes dominulus Pol d 1.0104 Food Plant Polistes Pol a 1 Pol d 1 316 45510893 Paper wasp Polistes dominulus Pol d 1.0103 Food Plant Polistes Pol a 1 Pol d 1 316 45510891 Paper wasp Polistes dominulus Pol d 1.0102 Food Plant Polistes Pol a 1 Pol d 1 316 45510889 Paper wasp Polistes dominulus Pol d 1.0101 Food Plant Polistes Pol a 1 Pol d 1 337 45510887 Paper wasp Polistes dominulus Pol d 4.0101 Food Plant Polistes Venom serine protease 277 30909091 Paper wasp Polistes exclamans Pol e 5.0101 Food Plant Polistes Pol 5 226 51093375 Paper wasp Polistes fuscatus Pol f 5 Food Plant Polistes Pol 5 205 549188 Paper wasp Polistes gallicus Pol g 5 Food Plant Polistes Pol 5 206 25091511 Paper wasp Polistes gallicus Unassigned Food Plant Polistes Pol a 1 Pol d 1 42 41017429 Para rubber tree Hevea brasiliensis Hev b 1.0101 Aero Plant Hevea Hev b 1 138 18839 Para rubber tree Hevea brasiliensis Hev b 10.0101 Aero Plant Hevea Hev b 10 233 348137 Para rubber tree Hevea brasiliensis Hev b 10.0102 Aero Plant Hevea Hev b 10 205 5777414 Para rubber tree Hevea brasiliensis Hev b 10.0103 Aero Plant Hevea Hev b 10 205 10862818 Para rubber tree Hevea brasiliensis Hev b 11.0101 Aero Plant Hevea Hev b 11 295 14575525 Para rubber tree Hevea brasiliensis Hev b 12 Aero Plant Hevea Hev b 12 116 20135538 Para rubber tree Hevea brasiliensis Hev b 13 Aero Plant Hevea Hev b 13 391 30909057 Para rubber tree Hevea brasiliensis Hev b 14.0101 Aero Plant Hevea Hev b 14 hevamine 208 313870530 Para rubber tree Hevea brasiliensis Hev b 2.0101 Aero Plant Hevea Hev b 2 374 1184668 Para rubber tree Hevea brasiliensis Hev b 2 Aero Plant Hevea Hev b 2 374 32765543 Para rubber tree Hevea brasiliensis Unassigned Aero Plant Hevea Hev b 2 374 124294783 Para rubber tree Hevea brasiliensis Unassigned Aero Plant Hevea Hev b 2 374 124294785 Para rubber tree Hevea brasiliensis Unassigned Aero Plant Hevea Hev b 2 374 124365249 Para rubber tree Hevea brasiliensis Unassigned Aero Plant Hevea Hev b 2 374 124365251 Para rubber tree Hevea brasiliensis Unassigned Aero Plant Hevea Hev b 2 374 124365253 Para rubber tree Hevea brasiliensis Unassigned Aero Plant Hevea Hev b 2 374 268037674 Para rubber tree Hevea brasiliensis Unassigned Aero Plant Hevea Hev b 2 374 270315180 Para rubber tree Hevea brasiliensis Unassigned Aero Plant Hevea Hev b 2 373 359359690 Para rubber tree Hevea brasiliensis Unassigned Aero Plant Hevea Hev b 2 374 387778882 Para rubber tree Hevea brasiliensis Unassigned Aero Plant Hevea Hev b 2 374 387778880 Para rubber tree Hevea brasiliensis Hev b 3.0101 Aero Plant Hevea Hev b 3 204 3818475 Para rubber tree Hevea brasiliensis Hev b 4.0101 Aero Plant Hevea Hev b 4 366 46410859 Para rubber tree Hevea brasiliensis Hev b 5 Aero Plant Hevea Hev b 5 151 1480457 Para rubber tree Hevea brasiliensis Hev b 6 Aero Plant Hevea Hev b 6 187 2832430 Para rubber tree Hevea brasiliensis Unassigned Aero Plant Hevea Hev b 6 43 73535415 Para rubber tree Hevea brasiliensis Unassigned Aero Plant Hevea Hev b 6 204 158342650 Para rubber tree Hevea brasiliensis Hev b 6.01 Aero Plant Hevea Hev b 6 204 168209 Para rubber tree Hevea brasiliensis Hev b 7.01 Aero Plant Hevea Hev b 7 388 1916805 Para rubber tree Hevea brasiliensis Hev b 7.02 Aero Plant Hevea Hev b 7 388 3087805 Para rubber tree Hevea brasiliensis Unassigned Aero Plant Hevea Hev b 7 388 3288200 Para rubber tree Hevea brasiliensis Hev b 7 Aero Plant Hevea Hev b 7 388 6707018 Para rubber tree Hevea brasiliensis Unassigned Aero Plant Hevea Hev b 7 387 41581137 Para rubber tree Hevea brasiliensis Hev b 8.0203 Aero Plant Hevea Hev b 8 131 6979171 Para rubber tree Hevea brasiliensis Hev b 8.0101 Aero Plant Hevea Hev b 8 131 3183706 Para rubber tree Hevea brasiliensis Hev b 8 Aero Plant Hevea Hev b 8 131 11513601 Para rubber tree Hevea brasiliensis Hev b 8.0201 Aero Plant Hevea Hev b 8 131 6979167 Para rubber tree Hevea brasiliensis Hev b 8.0202 Aero Plant Hevea Hev b 8 131 6979169 Para rubber tree Hevea brasiliensis Hev b 8.0102 Aero Plant Hevea Hev b 8 131 5689740 Para rubber tree Hevea brasiliensis Hev b 8.0204 Aero Plant Hevea Hev b 8 131 8919948 Para rubber tree Hevea brasiliensis Hev b 9 Aero Plant Hevea Hev b 9 445 9581744 Para rubber tree Hevea brasiliensis Unassigned Aero Plant Hevea Hev b 9 445 14423687 Para rubber tree Hevea brasiliensis subsp brasiliensis Hev b 11.0102 Aero Plant Hevea Hev b 11 295 27526732 Parasitic fish worm Anisakis pegreffii Unassigned Food Animal Anisakis Ani s 12 264 442577845 Parasitic fish worm Anisakis pegreffii Unassigned Food Animal Anisakis Ani s 12 264 442577847 parasitic fish worm Anisakis pegreffii Unassigned Food Animal Anisakis Ani s 12 264 442577849 Parasitic fish worm Anisakis pegreffii Unassigned Food Animal Anisakis Ani s 2 paramyosin 869 442577833 Parasitic fish worm Anisakis simplex Ani s 1 Food Animal Anisakis Ani s 1 protease inhibitor 194 47605452 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 1 protease inhibitor 163 442577863 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 1 protease inhibitor 163 442577865 Parasitic fish worm Anisakis simplex Ani s 10.0101 Food Animal Anisakis Ani s 10 231 272574378 Parasitic fish worm Anisakis simplex Ani s 11.0101 Food Animal Anisakis Ani s 11 307 323575361 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 11 160 323575363 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 11 287 323575365 Parasitic fish worm Anisakis simplex Ani s 12.0101 Food Animal Anisakis Ani s 12 295 323575367 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 12 264 442577851 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 12 264 442577853 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 12 264 442577855 Parasitic fish worm Anisakis simplex Ani s 2 Food Animal Anisakis Ani s 2 paramyosin 473 8453086 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 2 paramyosin 869 42559536 Parasitic fish worm Anisakis simplex Ani s 3 Food Animal Anisakis Ani s 3 tropomyosin 284 14423976 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 3 tropomyosin 284 350285785 Parasitic fish worm Anisakis simplex Ani s 4 Food Animal Anisakis Ani s 4 14 47605398 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 4 115 110346534 Parasitic fish worm Anisakis simplex Ani s 5.0101 Food Animal Anisakis Ani s 5 SXP/RAL-2 family protein 152 121308878 Parasitic fish worm Anisakis simplex Ani s 7.0101 Food Animal Anisakis Ani s 7 UA3-recognized allergen 1096 119524036 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 8 SXP/RAL-2 family protein 2 150 155676636 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 8 SXP/RAL-2 family protein 2 150 155676682 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 8 SXP/RAL-2 family protein 2 150 155676684 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 8 SXP/RAL-2 family protein 2 150 155676686 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 8 SXP/RAL-2 family protein 2 150 155676688 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 8 SXP/RAL-2 family protein 2 150 155676690 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 8 SXP/RAL-2 family protein 2 150 155676692 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 8 SXP/RAL-2 family protein 2 150 155676694 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 8 SXP/RAL-2 family protein 2 150 155676696 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis Ani s 8 SXP/RAL-2 family protein 2 150 155676698 Parasitic fish worm Anisakis simplex Ani s 9.0101 Food Animal Anisakis Ani s 9 147 157418806 Parasitic fish worm Anisakis simplex Unassigned Food Animal Anisakis simplex troponin-like 161 6065738 Parasitic nematode Strongyloides stercoralis Unassigned Work (parasite) Strongyloides L3NieAg.01 229 5669875 Parasitic nematode Onchocerca volvulus Unassigned Worm (parasite) Onchocerca tropomyosin 284 42559586 Parasitic roundworm Ascaris lumbricoides Unassigned Worm (parasite) Ascaris Asc s 1 134 2735096 Parasitic roundworm Ascaris lumbricoides Unassigned Worm (parasite) Ascaris Asc s 1 134 2735098 Parasitic roundworm Ascaris lumbricoides Unassigned Worm (parasite) Ascaris Asc s 1 133 2735102 Parasitic roundworm Ascaris lumbricoides Unassigned Worm (parasite) Ascaris Asc s 1 133 2735106 Parasitic roundworm Ascaris lumbricoides Unassigned Worm (parasite) Ascaris Asc s 1 267 2735108 Parasitic roundworm Ascaris lumbricoides Unassigned Worm (parasite) Ascaris Asc s 1 267 2735110 Parasitic roundworm Ascaris lumbricoides Unassigned Worm (parasite) Ascaris Asc s 1 267 2735112 Parasitic roundworm Ascaris lumbricoides Unassigned Worm (parasite) Ascaris Asc s 1 134 2735114 Parasitic roundworm Ascaris lumbricoides Unassigned Worm (parasite) Ascaris Asc s 1 134 2735118 Parasitic roundworm Ascaris lumbricoides Unassigned Worm (parasite) Ascaris Asc s 1 134 2735100 Parasitic roundworm Ascaris lumbricoides Asc | 3.0101 Worm (parasite) Ascaris tropomyosin Asc | 3 287 224016002 Parasitic roundworm Ascaris suum Asc s 1 Worm (parasite) Ascaris Asc s 1 68 299550 Parasitic roundworm Ascaris suum Asc s 1 Worm (parasite) Ascaris Asc s 1 1365 77416849 Parasitic roundworm Ascaris suum Unassigned Worm (parasite) Ascaris Asc s 1 134 343197079 Parasitic roundworm Ascaris suum Asc s 13.0101 Worm (parasite) Ascaris lumbricoides/suum Glutathione S- 206 1170109 Patagonian Grenadier Macruronus magellanicus Unassigned Food Animal Merluccius sp. Parvalbumin Hake 98 308191450 Patagonian Grenadier Macruronus magellanicus Unassigned Food Animal Merluccius sp. Parvalbumin Hake 108 308191461 Patagonian Grenadier Macruronus magellanicus Unassigned Food Anima Merluccius sp. Parvalbumin Hake 74 308191474 Pea Pisum sativum Pis s 1.0102 Food Plant Pisum Pis s 1 415 42414629 Pea Pisum sativum Pis s 1.0101 Food Plant Pisum Pis s 1 415 42414627 Pea Pisum sativum Pis s 2.0101 Food Plant Pisum Pis s 2 613 7339551 Peanut Arachis hypogaea Unassigned Food Plant Arachis Agglutinin (lectin) 273 253289 Peanut Arachis hypogaea Ara h 1 Food Plant Arachis Ara h 1 614 1168390 Peanut Arachis hypogaea Ara h 1 Food Plant Arachis Ara h 1 626 1168391 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 1 299 46560474 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 1 303 46560472 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 1 428 46560476 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 1 619 312233063 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 1 418 375332427 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 1 418 347447588 Peanut Arachis hypogaea Ara h 2.0201 Food Plant Arachis Ara h 2 172 26245447 Peanut Arachis hypogaea Ara h 2.0101 Food Plant Arachis Ara h 2 169 31322017 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 2 156 15418705 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 2 158 224747150 Peanut Arachis hypogaea Ara h 3.0101 Food Plant Arachis Ara h 3 Glycinin 507 3703107 Peanut Arachis hypogaea Ara h 3.0201 Food Plant Arachis Ara h 3 Glycinin 530 5712199 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 3 Glycinin 538 21314465 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 3 Glycinin 219 22135348 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 3 Glycinin 512 112380623 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 3 Glycinin 530 199732457 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 3 Glycinin 510 224036293 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 3 Glycinin 512 312233065 Peanut Arachis hypogaea Ara h 5 Food Plant Arachis Ara h 5 131 5902968 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 5 131 284810529 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 5 131 431812555 Peanut Arachis hypogaea Ara h 6 Food Plant Arachis Ara h 6 129 5923742 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 6 144 17225991 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 6 127 159163254 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 6 145 75114094 Peanut Arachis hypogaea Ara h 7.0101 Food Plant Arachis Ara h 7 160 5931948 Peanut Arachis hypogaea Ara h 7.0201 Food Plant Arachis Ara h 7 164 158121995 Peanut Arachis hypogaea Ara h 8.0101 Food Plant Arachis Ara h 8 157 37499626 Peanut Arachis hypogaea Ara h 8.0201 Food Plant Arachis Ara h 8 153 145904610 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 8 157 169786740 Peanut Arachis hypogaea Unassigned Food Plant Arachis Ara h 8 157 110676574 Peanut Arachis hypogaea Ara h 9.0101 Food Plant Arachis Ara h 9 LTP isoallergens 116 161087230 Peanut Arachis hypogaea Ara h 9.0201 Food Plant Arachis Ara h 9 LTP isoallergens 92 161610580 Pear Pyrus communis Pyr c 3.0101 Food Plant Pyrus LTP Pyr c 3 IUIS 115 6715524 Pear Pyrus communis Unassigned Food Plant Pyrus LTP Pyr c 3 IUIS 94 355525862 Pear Pyrus communis Unassigned Food Plant Pyrus LTP Pyr c 3 IUIS 94 355525860 Pear Pyrus communis Unassigned Food Plant Pyrus LTP Pyr c 3 IUIS 94 355525856 Pear Pyrus communis Pyr c 1.0101 Food Plant Pyrus Pyr c 1 159 14423877 Pear Pyrus communis Pyr c 4 Food Plant Pyrus Pyr c 4 131 4761580 Pear Pyrus communis Pyr c 5 Food Plant Pyrus Pyr c 5 308 3243234 Pecan Carya illinoinensis Car i 1.0101 Food Plant Carya Car i 1 Seed storage protein 143 28207731 Pecan Carya illinoinensis Car i 4.0101 Food Plant Carya Car i 4 11s legumin 505 158998780 Pecan Carya illinoinensis Unassigned Food Plant Carya Car i 4 11s legumin 505 158998782 Penicillin Chemical Perennial ryegrass Lolium perenne Lol p 1 Aero Plant Lolium Lol p 1 263 126385 Perennial ryegrass Lolium perenne Lol p 1.0102 Aero Plant Lolium Lol p 1 252 168314 Perennial ryegrass Lolium perenne Lol p 1.0101 Aero Plant Lolium Lol p 1 263 168316 Perennial ryegrass Lolium perenne Lol p 1.0103 Aero Plant Lolium Lol p 1 263 6599300 Perennial ryegrass Lolium perenne Lol p 11 Aero Plant Lolium Lol p 11 134 47605808 Perennial ryegrass Lolium perenne Lol p 2.0101 Aero Plant Lolium Lol p 2 97 126386 Perennial ryegrass Lolium perenne Lol p 2 Aero Plant Lolium Lol p 2 88 939932 Perennial ryegrass Lolium perenne Lol p 3 Aero Plant Lolium Lol p 3 97 126387 Perennial ryegrass Lolium perenne Lol p 4.0101 Aero Plant Lolium Lol p 4 423 55859464 Perennial ryegrass Lolium perenne Lol p 5 Aero Plant Lolium Lol p 5 301 4416516 Perennial ryegrass Lolium perenne Lol p 5 Aero Plant Lolium Lol p 5 301 6634467 Perennial ryegrass Lolium perenne Lol p 5.0101 Aero Plant Lolium Lol p 5 339 455288 Perennial ryegrass Lolium perenne Lol p 5.0102 Aero Plant Lolium Lol p 5 307 332278195 Photographic developers Chemical Pig Sus scrofa Unassigned Aero animal Sus Porcine Pepsin 385 118572685 Pigweed Chenopodium album Che a 1 Aero Plant Chenopodium Che a 1 168 22074346 Pigweed Chenopodium album Che a 2 Aero Plant Chenopodium Che a 2 131 29465666 Pigweed Chenopodium album Unassigned Aero Plant Chenopodium Che a 2 133 238886048 Pigweed Chenopodium album Che a 3 Aero Plant Chenopodium Che a 3 86 29465668 Pine moth Thaumetopoea pityocampa Tha p 1.0101 Contact Thaumetopoea Tha p 1 full length 126 301030229 Pine moth Thaumetopoea pityocampa Tha p 2.0101 Contact Thaumetopoea Tha p 2 115 408387552 Pineapple Ananas comosus Ana c 2.0101 Aero Plant Ananas Ana c 2 Bromelain precursor 351 75277440 Pineapple Ananas comosus Ana c 1.0101 Food Plant Ananas profilin 131 75306610 Pistachio Pistacia vera Unassigned Food Plant Pistacia 11S globulin 472 156001070 Pistachio Pistacia vera Pis v 2.0101 Food Plant Pistacia 11S globulin 496 110349083 Pistachio Pistacia vera Pis v 2.0201 Food Plant Pistacia 11S globulin 472 110349085 Pistachio Pistacia vera Pis v 1.0101 Food Plant Pistacia Pis v 1 2S albumin 149 110349081 Pistachio Pistacia vera Pis v 3.0101 Food Plant Pistacia Pis v 3 vicilin 519 133711974 Pistachio Pistacia vera Pis v 4.0101 Food Plant Pistacia Pis v 4 230 149786150 Plum Prunus domestica Pru d 3 Food Plant Prunus Pru 3 91 9297015 Pomegranate Punica granatum Pun g 1.0101 Food Plant Punica Pun g 1 120 559797767 Pomegranate Punica granatum Pun g 1.0201 Food Plant Punica Pun g 1 120 559797765 Pomegranate Punica granatum Pun g 1.0301 Food Plant Punica Pun g 1 120 559797763 Potato Solanum tuberosum Unassigned Food Plant Solanum profilin-like 131 77416979 Potato Solanum tuberosum Unassigned Food Plant Solanum profilin-like 131 77999277 Potato Solanum tuberosum Unassigned Food Plant Solanum Sola t 1 386 21510 Potato Solanum tuberosum Unassigned Food Plant Solanum Sola t 1 386 21512 Potato Solanum tuberosum Unassigned Food Plant Solanum Sola t 1 386 21514 Potato Solanum tuberosum Unassigned Food Plant Solanum Sola t 1 386 169500 Potato Solanum tuberosum Sola t 1 Food Plant Solanum Sola t 1 386 158517845 Potato Solanum tuberosum Sola t 2 Food Plant Solanum Sola t 2 188 124148 Potato Solanum tuberosum Sola t 3 Food Plant Solanum Sola t 3 222 20141344 Potato Solanum tuberosum Sola t 3.0101 Food Plant Solanum Sola t 3 186 1575306 Potato Solanum tuberosum Sola t 4.0101 Food Plant Solanum Sola t 4 221 994779 Privet Ligustrum vulgare Lig v 1.0101 Aero Plant Ligustrum Lig v 1 145 3256210 Privet Ligustrum vulgare Lig v 1.0102 Aero Plant Ligustrum Lig v 1 145 3256212 rainbow trout Oncorhynchus mykiss Onc m 1.0101 Food Animal Oncorhynchus Rainbow trout parv Onc m 1 108 288559139 rainbow trout Oncorhynchus mykiss Onc m 1.0201 Food Animal Oncorhynchus Rainbow trout parv Onc m 1 107 288559140 Rape Brassica napus Unassigned Aero Plant Bra n Bra r 2 83 2129801 Rape Brassica napus Unassigned Aero Plant Bra n Bra r 2 83 2129802 Rape Brassica napus Bra n 1 Food Plant Bra n 1 125 75107016 Rape Brassica napus Unassigned Food Plant Brassica napus 2S albumin 109 26985163 Raspberry Rubus idaeus Rub i 1.0101 Food Plant Rubus Rub i 1 137 110180525 Raspberry Rubus idaeus Rub i 3.0101 Food Plant Rubus Rub i 3 117 110180523 Rat Rattus norvegicus Rat n 1 Aero Animal Rattus Rat n 1 181 127533 Rat Rattus norvegicus Rat n 1 Aero Animal Rattus Rat n 1 181 81890324 Rat Rattus norvegicus Rat n 1.0101 Aero Animal Rattus Rat n 1 177 204261 Red Fire Ant Solenopsis invicta Sol i 4 Venom or Solenopsis Sol g 4 Sol i 4 137 4038411 Red Fire Ant Solenopsis invicta Sol i 4.0101 Venom or Solenopsis Sol g 4 Sol i 4 137 4038409 Red Fire Ant Solenopsis invicta Unassigned Venom or Solenopsis Sol i 1 58 1336809 Red Fire Ant Solenopsis invicta Unassigned Venom or Solenopsis Sol i 1 25 1336811 Red Fire Ant Solenopsis invicta Unassigned Venom or Solenopsis Sol i 1 26 1336812 Red Fire Ant Solenopsis invicta Unassigned Venom or Solenopsis Sol i 1 26 1336813 Red Fire Ant Solenopsis invicta Sol i 1.0101 Venom or Solenopsis Sol i 1 346 51093373 Red Fire Ant Solenopsis invicta Sol i 2.0101 Venom or Solenopsis Sol i and Sol r Venom allergen II 138 549179 Red Fire Ant Solenopsis invicta Sol i 3.0101 Venom or Solenopsis Venom allergen III 234 2293571 Red cedar Juniperus virginiana Unassigned Aero Plant Juniperus Jun a 3 110 51316532 Red cedar Juniperus virginiana Jun v 1.0102 Aero Plant Juniperus Jun a/v 1 367 8843917 Red cedar Juniperus virginiana Jun v 1.0101 Aero Plant Juniperus Jun a/v 1 367 8843921 red squid Ommastrephes bartramii Unassigned Food Animal Ommastrephes tropomyosin 284 83715934 red swamp crayfish Procambarus clarkii Unassigned Food Animal Procambarus red crayfish arginine kinase 357 375298901 red swamp crayfish Procambarus clarkii Unassigned Food Animal Procambarus tropomysin 284 225348412 Rice Oryza sativa Ory s 1.0101 Aero Plant Oryza Ory s 1 263 1173557 Rice Oryza sativa Unassigned Aero Plant Oryza Ory s 1 267 8118439 Rice Oryza sativa (japonica cultivar-group) Ory s 1 Aero Plant Oryza Ory s 1 267 109913547 Rice Oryza sativa (japonica cultivar-group) Unassigned Aero Plant Oryza putative polcalcin Phl p 7 82 45736119 Rice Oryza sativa Unassigned Food Plant Oryza Glyoxalase I 291 84029333 Rice Oryza sativa (japonica cultivar-group) Unassigned Food Plant Oryza Glyoxalase I 291 16580747 Rice Oryza sativa (japonica cultivar-group) Unassigned Food Plant Oryza Trypsin alpha-amylase inhibitor 157 23616954 Rice Oryza sativa (japonica cultivar-group) Unassigned Food Plant Oryza Trypsin alpha-amylase inhibitor 165 218193 Rice Oryza sativa (japonica cultivar-group) Unassigned Food Plant Oryza Trypsin alpha-amylase inhibitor 157 218197 Rice Oryza sativa (japonica cultivar-group) Unassigned Food Plant Oryza Trypsin alpha-amylase inhibitor 111 1304216 Rice Oryza sativa (japonica cultivar-group) Unassigned Food Plant Oryza Trypsin alpha-amylase inhibitor 109 1304217 Rice Oryza sativa (japonica cultivar-group) Unassigned Food Plant Oryza Trypsin alpha-amylase inhibitor 113 1304218 Rice Oryza sativa (japonica cultivar-group) Unassigned Food Plant Oryza Trypsin alpha-amylase inhibitor 166 1398913 Rice Oryza sativa (japonica cultivar-group) Unassigned Food Plant Oryza Trypsin alpha-amylase inhibitor 160 1398915 Rice Oryza sativa (japonica cultivar-group) Unassigned Food Plant Oryza Trypsin alpha-amylase inhibitor 157 1398916 Rice Oryza sativa (japonica cultivar-group) Unassigned Food Plant Oryza Trypsin alpha-amylase inhibitor 160 1398918 Rice Oryza sativa (japonica cultivar-group) Unassigned Food Plant Oryza Trypsin alpha-amylase inhibitor 157 2827316 Rice Oryza sativa (japonica cultivar-group) Unassigned Food Plant Oryza Trypsin alpha-amylase inhibitor 166 114152865 Rice Oryza sativa (japonica cultivar-group) Unassigned Food Plant Oryza Trypsin alpha-amylase inhibitor 163 114152864 Rice Oryza sativa (japonica cultivar-group) Unassigned Food Plant Oryza Trypsin alpha-amylase inhibitor 160 23495787 Rice Oryza sativa (japonica cultivar-group) Unassigned Food Plant Oryza Trypsin alpha-amylase inhibitor 160 23616947 Rye Secale cereale Unassigned Aero Plant Secale Sec c 4 520 55859456 Rye Secale cereale Unassigned Aero Plant Secale Sec c 4 518 55859454 Rye Secale cereale Unassigned Aero Plant Secale Sec c 5 16 75140047 Rye Secale cereale Sec c 5.0101 Food Plant Secale Sec c 5 292 332205751 Rye Secale cereale Sec c 20.0101 Food Plant Secale Sec c 20 23 1699225 Rye Secale cereale Sec c 20.0201 Food Plant Secale Sec c 20 29 1699228 Rye Secale cereale Sec c 38.0101 Food Plant Secale Sec c 38.01 26 994865 Saffron crocus Crocus sativus Cro s 2.0101 Aero Plant Crocus profilin Cro s 2 131 58700651 Salmon Salmo salar Sal s 1 Food Animal Salmo Sal s 1 108 18281421 Salmon Salmo salar Unassigned Food Animal Salmo Sal s 1 109 209734468 Salmon Salmo salar Sal s 1.0101 Food Animal Salmo Sal s 1 109 1322183 Salmon Salmo salar Unassigned Food Animal Salmo Sal s 2 enolase 432 385145180 Salmon Salmo salar Sal s 2.0101 Food Anima Salmo Sal s 2 enolase 434 197632415 Salmon Salmo salar Unassigned Food Animal Salmo Sal s 3 aldolase 363 385145176 Salmon Salmo salar Sal s 3.0101 Food Animal Salmo Sal s 3 aldolase 363 213511774 Sapodilla plum Manilkara zapota Unassigned Food Plant Manilkara Thaumatin like protein 1 12 442580988 Sapodilla plum Manilkara zapota Unassigned Food Plant Manilkara Thaumatin like protein 1 9 442570282 Sapodilla plum Manilkara zapota Unassigned Food Plant Manilkara Thaumatin like protein 1 207 663434113 Scabies mite Sarcoptes scabiei type suis Unassigned Aero mite Sarcoptes Apolipoprotein Ssag1.2 310 507480520 Scabies mite Sarcoptes scabiei type hominis Unassigned Venom or Sarcoptes Apolipoprotein Ssag1.2 330 27462848 Scabies mite Sarcoptes scabiei type hominis Unassigned Venom or Sarcoptes cysteine protease CO8 340 46406002 Scabies mite Sarcoptes scabiei type hominis Unassigned Venom or Sarcoptes cysteine proteases FO4 338 46406012 Scabies mite Sarcoptes scabiei type hominis Unassigned Venom or Sarcoptes cysteine proteases FO4 339 46406014 Scabies mite Sarcoptes scabiei type hominis Unassigned Venom or Sarcoptes cysteine proteases FO4 273 46406016 Scabies mite Sarcoptes scabiei type hominis Unassigned Venom or Sarcoptes Glutathione S-transferase Mu 219 27462836 Scabies mite Sarcoptes scabiei type hominis Unassigned Venom or Sarcoptes Glutathione S-transferase Mu 219 60920770 Schistosoma Schistosoma japonicum Unassigned Protozoan Schistosoma profilin 129 29841461 Schistosoma Schistosoma japonicum Unassigned Protozoan Schistosoma tegumental antigen 191 2739154 Semen Sesame Sesamum indicum Ses i 1 Food Plant Sesamum Ses i 1 153 13183175 Sesame Sesamum indicum Unassigned Food Plant Sesamum Ses i 1 153 209165427 Sesame Sesamum indicum Ses i 2 Food Plant Sesamum Ses i 2 148 5381323 Sesame Sesamum indicum Ses i 3 Food Plant Sesamum Ses i 3 585 13183177 Sesame Sesamum indicum Ses i 4.0101 Food Plant Sesamum Ses i 4 oleosin 166 10834827 Sesame Sesamum indicum Unassigned Food Plant Sesamum Ses i 5 oleosin 145 198250343 Sesame Sesamum indicum Ses i 5.0101 Food Plant Sesamum Ses i 5 oleosin 145 5381321 Sesame Sesamum indicum Ses i 6.0101 Food Plant Sesamum Ses i 6 459 5381325 Sesame Sesamum indicum Ses i 7.0101 Food Plant Sesamum Ses i 7 497 13183173 Shaggy mane Coprinus comatus Cop c 1 Food Fungi Coprinus Cop c 1 81 4538529 Shallow-water cape hake Merluccius capensis Unassigned Food Animal Merluccius sp. Parvalbumin Hake 108 308191466 Short ragweed Ambrosia artemisiifolia Amb a 1.0101 Aero Plant Ambrosia Amb a 1 396 113475 Short ragweed Ambrosia artemisiifolia Amb a 1.0201 Aero Plant Ambrosia Amb a 1 398 113476 Short ragweed Ambrosia artemisiifolia Amb a 1.0301 Aero Plant Ambrosia Amb a 1 397 113477 Short ragweed Ambrosia artemisiifolia Amb a 1.0401 Aero Plant Ambrosia Amb a 1 392 113478 Short ragweed Ambrosia artemisiifolia Amb a 1.0303 Aero Plant Ambrosia Amb a 1 397 166443 Short ragweed Ambrosia artemisiifolia Unassigned Aero Plant Ambrosia Amb a 1 396 302127810 Short ragweed Ambrosia artemisiifolia Amb a 1.0202 Aero Plant Ambrosia Amb a 1 398 302127812 Short ragweed Ambrosia artemisiifolia Amb a 1.0304 Aero Plant Ambrosia Amb a 1 397 302127814 Short ragweed Ambrosia artemisiifolia Amb a 1.0305 Aero Plant Ambrosia Amb a 1 397 302127816 Short ragweed Ambrosia artemisiifolia Unassigned Aero Plant Ambrosia Amb a 1 397 302127818 Short ragweed Ambrosia artemisiifolia Unassigned Aero Plant Ambrosia Amb a 1 397 302127820 Short ragweed Ambrosia artemisiifolia Unassigned Aero Plant Ambrosia Amb a 1 397 302127822 Short ragweed Ambrosia artemisiifolia Amb a 1.0402 Aero Plant Ambrosia Amb a 1 387 302127824 Short ragweed Ambrosia artemisiifolia Unassigned Aero Plant Ambrosia Amb a 1 397 302127826 Short ragweed Ambrosia artemisiifolia Amb a 1.0502 Aero Plant Ambrosia Amb a 1 397 302127828 Short ragweed Ambrosia artemisiifolia Amb a 10.0101 Aero Plant Ambrosia Amb a 10 160 62249491 Short ragweed Ambrosia artemisiifolia Amb a 2 Aero Plant Ambrosia Amb a 2 397 113479 Short ragweed Ambrosia artemisiifolia Unassigned Aero Plant Ambrosia Amb a 4 164 285005079 Short ragweed Ambrosia artemisiifolia Amb a 4.0101 Aero Plant Ambrosia Amb a 4 164 291197394 Short ragweed Ambrosia artemisiifolia Unassigned Aero Plant Ambrosia Amb a 4 111 291482306 Short ragweed Ambrosia artemisiifolia Unassigned Aero Plant Ambrosia Amb a 4 140 291482308 Short ragweed Ambrosia artemisiifolia Unassigned Aero Plant Ambrosia Amb a 4 134 291482310 Short ragweed Ambrosia artemisiifolia Unassigned Aero Plant Ambrosia Amb a 4 96 291482314 Short ragweed Ambrosia artemisiifolia Unassigned Aero Plant Ambrosia Amb a 4 110 291482316 Short ragweed Ambrosia artemisiifolia Unassigned Aero Plant Ambrosia Amb a 4 116 291482318 Short ragweed Ambrosia artemisiifolia Amb a 6 Aero Plant Ambrosia Amb a 6 118 14285595 Short ragweed Ambrosia artemisiifolia Unassigned Aero Plant Ambrosia Amb a 8 profilin 133 34851182 Short ragweed Ambrosia artemisiifolia Unassigned Aero Plant Ambrosia Amb a 8 profilin 131 34851180 Short ragweed Ambrosia artemisiifolia Unassigned Aero Plant Ambrosia Amb a 8 profilin 131 34851178 Short ragweed Ambrosia artemisiifolia Amb a 8.0101 Aero Plant Ambrosia Amb a 8 profilin 133 62249502 Short ragweed Ambrosia artemisiifolia Amb a 8.0102 Aero Plant Ambrosia Amb a 8 profilin 133 62249512 Short ragweed Ambrosia artemisiifolia Amb a 9.0101 Aero Plant Ambrosia Amb a 9 83 62249470 Short ragweed Ambrosia artemisiifolia Amb a 9.0102 Aero Plant Ambrosia Amb a 9 83 62249481 Short ragweed Ambrosia artemisiifolia (elatior) Amb a 3 Aero Plant Ambrosia Amb a 3 101 416636 Short ragweed Ambrosia artemisiifolia (elatior) Amb a 5 Aero Plant Ambrosia Amb a 5 Ra5 45 114090 Shrimp Crangon crangon Cra c 1.0101 Food Animal Crangon Cra c 1 tropomyosin 284 238477263 Shrimp Crangon crangon Cra c 2.0101 Food Animal Crangon Cra c 2 arginine kinase 356 238477265 Shrimp Crangon crangon Cra c 4.0101 Food Animal rangon Cra c 4 sarcoplasmic calcium- binding prot 193 238477327 Shrimp Crangon crangon Cra c 5.0101 Food Animal Crangon Cra c 5 myosin light chain 153 238477331 Shrimp Crangon crangon Cra c 6.0101 Food Animal Crangon Cra c 6 troponin C 150 238477333 Shrimp Crangon crangon Cra c 8.0101 Food Animal Crangon Cra c 8 triosephosphate isomerase 249 238477329 Silkworm Bombyx mori Bomb m 1.0101 Aero Insect Bombyx Bomb m 1 355 82658675 Silver hake Merluccius bilinearis Unassigned Food Animal Merluccius sp. Parvalbumin Hake 108 308191465 Silver hake Merluccius bilinearis Unassigned Food Animal Merluccius sp. Parvalbumin Hake 108 308191478 Silver hake Merluccius bilinearis Unassigned Food Animal Merluccius sp. Parvalbumin Hake 94 308191488 Silverfish Lepisma saccharina Lep s 1 Aero Insect Lepisma Tropomyosin 284 20387027 Silverfish Lepisma saccharina Unassigned Aero Insect Lepisma Tropomyosin 243 20387029 Smokybrown cockroach Periplaneta fuliginosa Unassigned Aero Insect Periplaneta Per 7 284 19310971 Snow Crab Chionoecetes opilio Unassigned Food Animal Chionoecetes tropomyosin 284 308191588 South American Pilchard Sardinops sagax Sar sa 1.0101 Food animal Sardinops Sar sa 1 parvalbumin 109 193247972 southern hake Merluccius australis australis Unassigned Food Animal Merluccius sp. Parvalbumin Hake 108 308191452 Southern hake Merluccius australis polylepis Unassigned Food Animal Merluccius sp. Parvalbumin Hake 108 308191453 Southern hake Merluccius australis polylepis Unassigned Food Animal Merluccius sp. Parvalbumin Hake 108 308191464 Southern Pacific hake Merluccius gayi Unassigned Food Animal Merluccius sp. Parvalbumin Hake 108 308191455 Southern Pacific hake Merluccius gayi Unassigned Food Animal Merluccius sp. Parvalbumin Hake 91 308191489 Soybean Glycine max Gly m 1.0101 Food Plant Glycine Gly m 1 80 123506 Soybean Glycine max Gly m 3.0102 Food Plant Glycine Gly m 3 131 3021373 Soybean Glycine max Unassigned Food Plant Glycine Gly m 3 131 156938901 Soybean Glycine max Gly m 3.0101 Food Plant Glycine Gly m 3 131 3021375 Soybean Glycine max Gly m 4 Food Plant Glycine Gly m 4 158 18744 Soybean Glycine max Unassigned Food Plant Glycine Gly m 5.0101 alpha subunit beta congl 605 18536 Soybean Glycine max Unassigned Food Plant Glycine Gly m 5.0101 alpha subunit beta congl 218 169927 Soybean Glycine max Gly m 5.0101 Food Plant Glycine Gly m 5.0101 alpha subunit beta congl 543 9967357 Soybean Glycine max Unassigned Food Plant Glycine Gly m 5.0201 alpha prime beta congly 639 169929 Soybean Glycine max Unassigned Food Plant Glycine Gly m 5.0201 alpha prime beta congly 621 15425631 Soybean Glycine max Gly m 5.0201 Food Plant Glycine Gly m 5.0201 alpha prime beta congly 559 9967361 Soybean Glycine max Unassigned Food Plant Glycine Gly m 5.0301 beta sub unit beta congl 439 15425637 Soybean Glycine max Gly m 5.0301 Food Plant Glycine Gly m 5.0301 beta sub unit beta congl 439 121282 Soybean Glycine max Unassigned Food Plant Glycine Gly m 6.0101 495 18615 Soybean Glycine max Gly m 6.0101 Food Plant Glycine Gly m 6.0101 495 169973 Soybean Glycine max Unassigned Food Plant Glycine Gly m 6.0201 485 18609 Soybean Glycine max Gly m 6.0201 Food Plant Glycine Gly m 6.0201 485 218265 Soybean Glycine max Gly m 6.0301 Food Plant Glycine Gly m 6.0301 481 18639 Soybean Glycine max Unassigned Food Plant Glycine Gly m 6.0401 562 18641 Soybean Glycine max Unassigned Food Plant Glycine Gly m 6.0401 562 732706 Soybean Glycine max Gly m 6.0401 Food Plant Glycine Gly m 6.0401 563 4249568 Soybean Glycine max Unassigned Food Plant Glycine Gly m 6.0501 516 169969 Soybean Glycine max Unassigned Food Plant Glycine Gly m 6.0501 240 169971 Soybean Glycine max Gly m 6.0501 Food Plant Glycine Gly m 6.0501 517 10566449 Soybean Glycine max Unassigned Food Plant Glycine Gly m 8 2s albumin 155 4097894 Soybean Glycine max Gly m 8.0101 Food Plant Glycine Gly m 8 2s albumin 158 351727517 Soybean Glycine max Unassigned Food Plant Glycine Gly m Bd 28K 373 187766751 Soybean Glycine max Unassigned Food Plant Glycine Gly m Bd 28K 373 187766749 Soybean Glycine max Unassigned Food Plant Glycine Gly m Bd 28K 373 187766747 Soybean Glycine max Unassigned Food Plant Glycine Gly m Bd 28K 455 187766755 Soybean Glycine max Unassigned Food Plant Glycine Gly m Bd 28K 476 410067729 Soybean Glycine max Unassigned Food Plant Glycine Gly m Bd 30 kDa 379 129353 Soybean Glycine max Unassigned Food Plant Glycine Gly m Bd 30 kDa 379 1199563 Soybean Glycine max Unassigned Food Plant Glycine Gly m Bd 30 kDa 379 3097321 Soybean Glycine max Unassigned Food Plant Glycine Major Gly 50 kDa allergen 17 85681057 Soybean Glycine max Unassigned Food Plant Glycine Trypsin inhibitor 217 18770 Soybean Glycine max Unassigned Food Plant Glycine Trypsin inhibitor 217 18772 Soybean Glycine max Unassigned Food Plant Glycine Trypsin inhibitor 216 256429 Soybean Glycine max Unassigned Food Plant Glycine Trypsin inhibitor 203 256635 Soybean Glycine max Unassigned Food Plant Glycine Trypsin inhibitor 204 256636 Soybean Glycine max Unassigned Food Plant Glycine Trypsin inhibitor 208 510515 Soybean Glycine soja Unassigned Food Plant Glycine Gly m 6.0401 563 806556 Storage mite Glycyphagus domesticus Gly d 2.0101 Aero Mite Glycyphagus Gly d 2 128 6179520 Storage mite Glycyphagus domesticus Gly d 2.0201 Aero Mite Glycyphagus Gly d 2 125 7160811 Storage mite Glycyphagus domesticus Unassigned Aero Mite Glycyphagus Gly d 2 141 33772588 Storage mite Lepidoglyphus destructor Unassigned Aero Mite Blomia Blo t 12 143 33943777 Storage mite Lepidoglyphus destructor Lep d 10.0101 Aero Mite Lepidoglyphus Lep d 10 284 6900304 Storage mite Lepidoglyphus destructor Lep d 13.0101 Aero Mite Lepidoglyphus Lep d 13 131 6523380 Storage mite Lepidoglyphus destructor Lep d 2.0102 Aero Mite Lepidoglyphus Lep d 2 141 21213898 Storage mite Lepidoglyphus destructor Lep d 2.0202 Aero Mite Lepidoglyphus Lep d 2 141 21213900 Storage mite Lepidoglyphus destructor Lep d 2 Aero Mite Lepidoglyphus Lep d 2 141 1582223 Storage mite Lepidoglyphus destructor Lep d 2 Aero Mite Lepidoglyphus Lep d 2 141 1582222 Storage mite Lepidoglyphus destructor Unassigned Aero Mite Lepidoglyphus Lep d 2 141 34495274 Storage mite Lepidoglyphus destructor Unassigned Aero Mite Lepidoglyphus Lep d 2 141 34495278 Storage mite Lepidoglyphus destructor Unassigned Aero Mite Lepidoglyphus Lep d 2 140 34495280 Storage mite Lepidoglyphus destructor Unassigned Aero Mite Lepidoglyphus Lep d 2 141 34495282 Storage mite Lepidoglyphus destructor Unassigned Aero Mite Lepidoglyphus Lep d 2 141 34495284 Storage mite Lepidoglyphus destructor Unassigned Aero Mite Lepidoglyphus Lep d 2 141 34495286 Storage mite Lepidoglyphus destructor Unassigned Aero Mite Lepidoglyphus Lep d 2 141 34495288 Storage mite Lepidoglyphus destructor Unassigned Aero Mite Lepidoglyphus Lep d 2 141 34495290 Storage mite Lepidoglyphus destructor Lep d 2.0101 Aero Mite Lepidoglyphus Lep d 2 98 587450 Storage mite Lepidoglyphus destructor Lep d 2.0201 Aero Mite Lepidoglyphus Lep d 2 141 999458 Storage mite Lepidoglyphus destructor Lep d 5.0102 Aero Mite Lepidoglyphus Lep d 5 171 34495292 Storage mite Lepidoglyphus destructor Lep d 5.0103 Aero Mite Lepidoglyphus Lep d 5 169 34495294 Storage mite Lepidoglyphus destructor Lep d 5.0101 Aero Mite Lepidoglyphus Lep d 5 110 6523378 Storage mite Lepidoglyphus destructor Lep d 7.0101 Aero Mite Lepidoglyphus Lep d 7 216 6706282 Strawberry Fragaria x ananassa Fra a 1 Food Plant Fragaria Fra a 1 160 90185692 Strawberry Fragaria x ananassa Fra a 1 Food Plant Fragaria Fra a 1 159 90185688 Strawberry Fragaria x ananassa Fra a 1 Food Plant Fragaria Fra a 1 160 90185684 Strawberry Fragaria x ananassa Fra a 1 Food Plant Fragaria Fra a 1 160 90185682 Strawberry Fragaria x ananassa Fra a 1 Food Plant Fragaria Fra a 1 160 88082485 Strawberry Fragaria x ananassa Unassigned Food Plant Fragaria Fra a 1 162 550544407 Strawberry Fragaria x ananassa Fra a 3.0101 Food Plant Fragaria Fra a 3 117 18477856 Strawberry Fragaria x ananassa Fra a 3.0102 Food Plant Fragaria Fra a 3 117 67937767 Strawberry Fragaria x ananassa Fra a 3.0201 Food Plant Fragaria Fra a 3 117 67937765 Strawberry Fragaria x ananassa Fra a 3.0202 Food Plant Fragaria Fra a 3 117 67937773 Sulfites Food Sulfonamides Chemical Sunflower Helianthus annuus Hel a 2 Aero Plant Helianthus Hel a 2 133 3581965 Sunflower Helianthus annuus Hel a 3.0101 Food Plant Helianthus Hel a 3 116 31324341 Sunflower Helianthus annuus Unassigned Food Plant Helianthus Seed 2S albumin 141 112745 Sweet vernal grass Anthoxanthum odoratum Unassigned Aero Plant Anthoxanthum Ant o 1 26 320607 Sweet vernal grass Anthoxanthum odoratum Ant o 1.0101 Aero Plant Anthoxanthum Ant o 1 32 75139986 Sweet vernal grass Anthoxanthum odoratum Unassigned Aero Plant Anthoxanthum Ant o 1 32 75139990 Swordfish Xiphias gladius Xip g 1.0101 Food Animal Xiphias Xip g 1 beta-parvalbumin 109 222352960 Tall fescue Schedonorus arundinaceus Unassigned Aero Plant Festuca group 1 allergen 35 75139991 Tall fescue Schedonorus arundinaceus Unassigned Aero Plant Festuca group 1 allergen 17 320610 Tall fescue Schedonorus arundinaceus Unassigned Aero Plant Festuca group 1 allergen 20 320611 Tartrazine Food Tegretol Chemical Tetracycline Chemical Thistle Salsola kali Sal k 1.0302 Aero Plant Salsola pectin methylesterase Sal k 1.01 & 1.02 339 59895728 Thistle Salsola kali Sal k 1.0301 Aero Plant Salsola pectin methylesterase Sal k 1.01 & 1.02 339 59895730 Thistle Salsola kali Unassigned Aero Plant Salsola pectin methylesterase Sal k 1.01 & 1.02 339 225810597 Thistle Salsola kali Sal k 1.0101 Aero Plant Salsola Sal k 1 42 25090947 Thistle Salsola kali Unassigned Aero Plant Salsola Sal k 3 pollen allergen 757 225810599 Thistle Salsola kali Sal k 4.0101 Aero Plant Salsola Sal k 4 profilin 133 239916566 Thistle Salsola kali Unassigned Aero Plant Salsola Sal k 4 profilin 133 589912885 Thistle Salsola kali Sal k 4.0201 Aero Plant Salsola Sal k 4 profilin 133 300490499 Thistle Salsola kali Sal k 5.0101 Aero Plant Salsola Sal k 5 151 300490501 Thistle Salsola kali Sal k 1.0201 Aero Plant Salsola pectin methylesterase Sal k 1.01 & 1.02 362 51242679 Tobacco Nicotiana tabacum Unassigned Aero Plant Nicotiana villin 520 57283139 Tobacco Nicotiana tabacum Unassigned Aero Plant Nicotiana villin 559 57283137 Tomato lanum lycopersicum (Lycopersicon esculentu Sola | 1.0101 Food Plant Solanum Sola | 1 profilin (Lyc e 1) 131 16555787 Tomato lanum lycopersicum (Lycopersicon esculentu Lyc e 1 Food Plant Solanum Sola | 1 profilin (Lyc e 1) 131 17224229 Tomato lanum lycopersicum (Lycopersicon esculentu Sola | 2.0101 Food Plant Solanum Sola | 2 Beta-fructofuranosidase (Lyc e 2) 553 18542113 Tomato lanum lycopersicum (Lycopersicon esculentu Sola | 2.0201 Food Plant Solanum Sola | 2 Beta-fructofuranosidase (Lyc e 2) 636 18542115 Tomato lanum lycopersicum (Lycopersicon esculentu Unassigned Food Plant Solanum Sola | 3 LTP (Lyc e 3) 114 71360928 Tomato lanum lycopersicum (Lycopersicon esculentu Sola | 3.0101 Food Plant Solanum Sola | 3 LTP (Lyc e 3) 114 1816535 Tomato lanum lycopersicum (Lycopersicon esculentu Sola | 4.0101 Food Plant Solanum Sola | 4 PR-10 (Lyc e 4) 178 2887310 Tomato lanum lycopersicum (Lycopersicon esculentu Sola | 4.0201 Food Plant Solanum Sola | 4 PR-10 (Lyc e 4) 160 565380268 Tomato lanum lycopersicum (Lycopersicon esculentu Unassigned Food Plant Solanum Sola | 4 PR-10 (Lyc e 4) 160 565380238 Tropical Fire Ant Solenopsis geminata Sol g 4.0101 Venom or Solenopsis Sol g 4 Sol i 4 137 7638028 Tropical Fire Ant Solenopsis geminata Sol g 4.0201 Venom or Solenopsis Sol g 4 Sol i 4 137 7638030 Trumpet lily Lilium longiflorum Unassigned Aero Plant Lilium polygalacturonase 413 73913442 Tsetse fly Glossina morsitans morsitans Unassigned Venom or Glossina Glo m 5 258 289740263 Tsetse fly Glossina morsitans morsitans Unassigned Venom or Glossina Glo m 5 259 289742475 Tsetse fly Glossina morsitans morsitans Unassigned Venom or Glossina Glo m 5 222 289742483 Tsetse fly Glossina morsitans morsitans Glo m 5.0101 Venom or Glossina Glo m 5 259 8927462 Turnip Brassica rapa Unassigned Aero Plant Bra n Bra r 2 80 2129805 Turnip Brassica rapa subsp rapa Unassigned Aero Plant Bra n Bra r 2 83 59800146 Turnip Brassica rapa subsp rapa Bra r 2.0101 Contact Brassica Bra r 2 91 32363456 Turnip Brassica rapa Bra r 1.0101 Food Plant Brassica Bra r 1 178 17697 Turnip Brassica rapa Bra r 5.0101 Food Plant Brassica Calcim binding protein Group I 79 1255540 Velvet grass Holcus lanatus Hol | 1.0101 Aero Plant Holcus Hol | 1 265 414703 Velvet grass Holcus lanatus Hol | 1.0102 Aero Plant Holcus Hol | 1 248 1167836 Velvet grass Holcus lanatus Unassigned Aero Plant Holcus Hol | 1 263 3860384 Velvet grass Holcus lanatus Unassigned Aero Plant Holcus Hol | 5 20 75140046 Velvet grass Holcus lanatus Hol | 5.0201 Aero Plant Holcus Hol | 5 240 2266623 Velvet grass Holcus lanatus Hol | 5.0101 Aero Plant Holcus Hol | 5 264 2266625 Velvet grass Holcus lanatus Unassigned Aero Plant Holcus Hol 1 5 296 11991229 Wasp Vespa mandarinia Vesp m 5.0101 Venom or Vespa Vesp c 5 202 6136165 Wasp Vespula flavopilosa Ves f 5.0101 Venom or Vespula Ves f 5 204 549189 Wasp Vespula germanica Unassigned Venom or Vespula Phospholipase A1- Ves m/v 1 300 74035843 Wasp Vespula germanica Ves g 5.0101 Venom or Vespula Ves f 5 204 549190 Wasp Vespula germanica Unassigned Venom or Vespula Ves f 5 204 74035841 Wasp Vespula germanica Unassigned Venom or Vespula Ves v 2 331 116174180 Wasp Vespula germanica Unassigned Venom or Vespula Ves v 2 323 116174182 Wasp Vespula maculifrons Ves m 1.0101 Venom or Vespula Phospholipase A1- Ves m/v 1 300 1709545 Wasp Vespula maculifrons Ves m 5.0101 Venom or Vespula Ves f 5 204 549191 Wasp Vespula maculifrons Unassigned Venom or Vespula Ves f 5 227 85681830 Wasp Vespula maculifrons Unassigned Venom or Vespula Ves m 2 Hyaluronidase 31 313118253 Wasp Vespula pensylvanica Ves p 5.0101 Venom or Vespula Ves f 5 204 549192 Wasp Vespula squamosa Ves s 5.0101 Venom or Vespula Ves f 5 205 549193 Wasp Vespula squamosa Unassigned Venom or Vespula Ves s 1 phospholipase 298 313471398 Wasp Vespula vidua Ves vi 5.0101 Venom or Vespula Ves f 5 206 549194 Wasp Vespula vulgaris Ves v 1.0101 Venom or Vespula Phospholipase A1- Ves m/v 1 336 897647 Wasp Vespula vulgaris Ves v 5.0101 Venom or Vespula Ves f 5 227 162551 Wasp Vespula vulgaris Ves v 5 Venom or Vespula Ves f 5 204 4826574 Wasp Vespula vulgaris Ves v 5 Venom or Vespula Ves f 5 209 11514279 Wasp Vespula vulgaris Ves v 2 Venom or Vespula Ves v 2 331 1346323 Wasp Vespula vulgaris Ves v 2.0101 Venom or Vespula Ves v 2 340 62147665 Wasp Vespula vulgaris Unassigned Venom or Vespula Ves v 2 331 109157163 Wasp Vespula vulgaris Ves v 3.0101 Venom or Vespula Ves v 3 dipeptidylpeptidase IV 776 167782086 Wasp Polybia paulista Unassigned Food Plant Polybia p hyaluronidase 345 302201583 Wasp Polybia paulista Unassigned Food Plant Polybia p hyaluronidase 288 302425085 Wasp Polybia paulista Unassigned Food Plant Polybia p venom allergen 5 141 290792375 Wasp Polybia paulista Unassigned Food Plant Polybia p venom allergen 5 207 302595972 Wasp Polybia paulista Pol p 1.0101 Food Plant Polybia Pol p 1.0101 phospholipase 322 166216292 Wasp Polybia paulista Unassigned Food Plant Polybia Pol p 1.0101 phospholipase 302 315190620 Weed Parietaria judaica Par j 1 Aero Plant Parietaria Par j 1 143 741844 Weed Parietaria judaica Par j 1.0102 Aero Plant Parietaria Par j 1 176 1532058 Weed Parietaria judaica Par j 1.0101 Aero Plant Parietaria Par j 1 133 992612 Weed Parietaria judaica Par j 1.0103 Aero Plant Parietaria Par j 1 139 95007033 Weed Parietaria judaica Par j 1.0201 Aero Plant Parietaria Par j 1 138 706811 Weed Parietaria judaica Par j 2.0102 Aero Plant Parietaria Par j 2 133 1532056 Weed Parietaria judaica Par j 2.0101 Aero Plant Parietaria Par j 2 133 2497750 Weed Parietaria judaica Par j 3.0102 Aero Plant Parietaria Par j 3 profilin 131 14423869 Weed Parietaria judaica Par j 3.0101 Aero Plant Parietaria Par j 3 profilin 132 14423876 Weed Parietaria judaica Par j 3.0201 Aero Plant Parietaria Par j 3 profilin 131 444175753 Weed Parietaria judaica Par j 4.0101 Aero Plant Parietaria Par j 4 84 201071363 Weed Parietaria officinalis Par o 1 Aero Plant Parietaria Par o 1 12 75139847 Weed Parietaria officinalis Par o 1 Aero Plant Parietaria Par o 1 17 1311509 Weed Parietaria officinalis Par o 1 Aero Plant Parietaria Par o 1 15 1311510 Weed Parietaria officinalis Par o 1 Aero Plant Parietaria Par o 1 15 1311511 Weed Parietaria officinalis Par o 1 Aero Plant Parietaria Par o 1 15 1311512 Weed Parietaria officinalis Par o 1 Aero Plant Parietaria Par o 1 30 1311513 Weed Parietaria officinalis Par o 1 Aero Plant Parietaria Par o 1 24 1836011 Weed Parietaria officinalis Unassigned Aero Plant Parietaria Par o 1 25 1836010 Western conenose Triatoma protracta Tria p 1 Venom or Triatoma Tria p 1 169 15426413 Western ragweed Ambrosia psilostachya Amb p 5.0101 Aero Plant Ambrosia Amb a 5 Ra5 77 515953 Western ragweed Ambrosia psilostachya Unassigned Aero Plant Ambrosia Amb a 5 Ra5 77 515954 Western ragweed Ambrosia psilostachya Amb p 5.0201 Aero Plant Ambrosia Amb a 5 Ra5 77 515955 Western ragweed Ambrosia psilostachya Unassigned Aero Plant Ambrosia Amb a 5 Ra5 77 515956 Western ragweed Ambrosia psilostachya Unassigned Aero Plant Ambrosia Amb a 5 Ra5 77 515957 Wheat Triticum aestivum Unassigned Aero Plant Triticum Tri a 14 LTP_amylase inhibitor 113 417370 Wheat Triticum aestivum Unassigned Aero Plant Triticum Bakers asthma allergen #4 27 3913017 Wheat Triticum aestivum Unassigned Aero Plant Triticum flour Glutathione Transferase 222 190684057 Wheat Triticum aestivum Tri a 29.0101 Aero Plant Triticum Tri a 29 120 253783731 Wheat Triticum aestivum Tri a 29.0201 Aero Plant Triticum Tri a 29 120 283465827 Wheat Triticum aestivum Unassigned Aero Plant Triticum Tri a 32 Peroxiredoxin 218 190684059 Wheat Triticum aestivum Tri a 32.0101 Aero Plant Triticum Tri a 32 Peroxiredoxin 218 75324900 Wheat Triticum aestivum Unassigned Aero Plant Triticum Tri a 39 serine proteinase inhibitor-lik 84 154101366 Wheat Triticum aestivum Unassigned Aero Plant Triticum Tri a 39 serine proteinase inhibitor-lik 84 122065237 Wheat Triticum aestivum Tri a 39.0101 Aero Plant Triticum Tri a 39 serine proteinase inhibitor-lik 84 403213259 Wheat Triticum aestivum Unassigned Gliadin Triticum alpha/beta gliadin 307 21673 Wheat Triticum aestivum Unassigned Gliadin Triticum alpha/beta gliadin 296 21757 Wheat Triticum aestivum Unassigned Gliadin Triticum alpha/beta gliadin 286 21761 Wheat Triticum aestivum Unassigned Gliadin Triticum alpha/beta gliadin 313 21765 Wheat Triticum aestivum Unassigned Gliadin Triticum alpha/beta gliadin 318 170710 Wheat Triticum aestivum Unassigned Gliadin Triticum alpha/beta gliadin 291 170712 Wheat Triticum aestivum Unassigned Gliadin Triticum alpha/beta gliadin 313 170718 Wheat Triticum aestivum Unassigned Gliadin Triticum alpha/beta gliadin 286 170720 Wheat Triticum aestivum Unassigned Gliadin Triticum alpha/beta gliadin 262 170722 Wheat Triticum aestivum Unassigned Gliadin Triticum alpha/beta gliadin 297 170724 Wheat Triticum aestivum Unassigned Gliadin Triticum alpha/beta gliadin 282 170726 Wheat Triticum aestivum Unassigned Gliadin Triticum alpha/beta gliadin 186 170728 Wheat Triticum aestivum Unassigned Gliadin Triticum alpha/beta gliadin 259 1304264 Wheat Triticum aestivum Unassigned Gliadin Triticum omega-5 gliadin Tri a 19 366 508732623 Wheat Triticum aestivum Tri a 12.0101 Gliadin Triticum Tri a 12 131 548948848 Wheat Triticum aestivum Tri a 12.0102 Gliadin Triticum Tri a 12 131 548948850 Wheat Triticum aestivum Tri a 12.0104 Gliadin Triticum Tri a 12 131 207366248 Wheat Triticum aestivum Tri a 15.0101 Gliadin Triticum Tri a 15 121 283465829 Wheat Triticum aestivum Unassigned Gliadin Triticum Tri a 20 302 170702 Wheat Triticum aestivum Unassigned Gliadin Triticum Tri a 20 291 170708 Wheat Triticum aestivum Unassigned Gliadin Triticum Tri a 20 251 170736 Wheat Triticum aestivum Unassigned Gliadin Triticum Tri a 20 327 170738 Wheat Triticum aestivum Unassigned Gliadin Triticum Tri a 20 279 1063270 Wheat Triticum aestivum Unassigned Gliadin Triticum Tri a 20 285 62484809 Wheat Triticum aestivum Tri a 20.0101 Gliadin Triticum Tri a 20 279 508732621 Wheat Triticum aestivum Tri a 21.0101 Gliadin Triticum Tri a 21 alpha, beta-gliadin 281 283476402 Wheat Triticum aestivum Tri a 25.0101 Gliadin Triticum Tri a 25 125 8980491 Wheat Triticum aestivum Unassigned Gliadin Triticum Tri a 26 794 508732625 Wheat Triticum aestivum Tri a 26.0101 Gliadin Triticum Tri a 26 848 288860106 Wheat Triticum aestivum Tri a 26.0201 Gliadin Triticum Tri a 26 795 71084277 Wheat Triticum aestivum Tri a 28.0101 Gliadin Triticum Tri a 28 119 66841026 Wheat Triticum aestivum Tri a 33.0101 Gliadin Triticum Tri a 33 Serine protease inhibitor 398 5734506 Wheat Triticum aestivum Tri a 34.0101 Gliadin Triticum Tri a 34 GAPDH 337 253783729 Wheat Triticum aestivum Unassigned Gliadin Triticum Tri a 36 304 170730 Wheat Triticum aestivum Unassigned Gliadin Triticum Tri a 36 323 170732 Wheat Triticum aestivum Unassigned Gliadin Triticum Tri a 36 244 170734 Wheat Triticum aestivum Unassigned Gliadin Triticum Tri a 36 283 508732627 Wheat Triticum aestivum Unassigned Food Plant Triticum 5a2 protein 94 66840998 Wheat Triticum aestivum Unassigned Food Plant Triticum aAl CM16_17 143 21711 Wheat Triticum aestivum Unassigned Food Plant Triticum alpha/beta gliadin 286 21755 Wheat Triticum aestivum Tri a 19.0101 Food Plant Triticum omega-5 gliadin Tri a 19 439 73912496 Wheat Triticum aestivum Unassigned Food Plant Triticum omega-5 gliadin Tri a 19 359 208605344 Wheat Triticum aestivum Unassigned Food Plant Triticum omega-5 gliadin Tri a 19 272 208605346 Wheat Triticum aestivum Unassigned Food Plant Triticum omega-5 gliadin Tri a 19 346 208605348 Wheat Triticum aestivum Unassigned Food Plant Triticum putative leucine-rich repeat protein 137 66840996 Wheat Triticum aestivum Unassigned Food Plant Triticum serine carboxypeptidase II 260 66840994 Wheat Triticum aestivum Unassigned Food Plant Triticum serine carboxypeptidase II 444 125987805 Wheat Triticum aestivum Unassigned Food Plant Triticum Thaumatin-like 173 135917 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 12 131 190684061 Wheat Triticum aestivum Tri a 12.0103 Food Plant Triticum Tri a 12 131 548948852 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 26 830 21743 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 26 648 21751 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 26 660 21779 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 26 39 21793 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 26 705 22090 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 26 815 170743 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 26 838 736319 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 26 101 897811 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 29 145 21701 Wheat Triticum aestivum Tri a 30.0101 Food Plant Triticum Tri a 30 168 21713 Wheat Triticum aestivum Tri a 31.0101 Food Plant Triticum Tri a 31 253 11124572 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 33 Serine protease inhibitor 399 1885350 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 36 307 21773 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 36 356 21783 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 36 373 75317968 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 36 229 886963 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 36 261 886965 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 36 276 886967 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 36 285 75219081 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 36 326 62550933 Wheat Triticum aestivum Tri a 36.0101 Food Plant Triticum Tri a 36 369 335331566 Wheat Triticum aestivum Tri a 37.0101 Food Plant Triticum Tri a 37 alpha purothionin 137 4007850 Wheat Triticum turgidum subsp durum Unassigned Food Plant Triticum Tri a 36 295 21926 Wheat Triticum turgidum subsp durum Unassigned Food Plant Triticum Tri a 36 285 21930 Wheat Triticum urartu Unassigned Food Plant Triticum alpha/beta gliadin 296 170740 Wheat Triticum aestivum Unassigned Food Plant Triticum Tri a 27.0101 Thiol reductase 203 30793446 Wheat Triticum turgidum subsp durum Unassigned Food Plant Triticum aAl CM16_17 143 21916 Wheat Triticum turgidum subsp durum Unassigned Food Plant Triticum Tri a 29 145 21920 white lupine Lupinus albus Unassigned Food Plant Lupinus albus congluten beta 531 89994190 White Mulberry Morus alba var. atropurpurea Unassigned Food Plant Morus winter accumulating protein 157 610664572 White mustard Sinapis alba Sin a 1 Food Plant Sinapis Sin a 1.01 145 1009434 White mustard Sinapis alba Sin a 1 Food Plant Sinapis Sin a 1.01 145 1009436 White mustard Sinapis alba Sin a 1 Food Plant Sinapis Sin a 1.01 145 1009438 White mustard Sinapis alba Sin a 1 Food Plant Sinapis Sin a 1.01 145 1009440 White mustard Sinapis alba Sin a 1 Food Plant Sinapis Sin a 1.01 145 1009442 White mustard Sinapis alba Sin a 1.0101 Food Plant Sinapis Sin a 1.01 145 51338758 White mustard Sinapis alba Sin a 2.0101 Food Plant Sinapis Sin a 2.01 11S globulin 510 62240390 White mustard Sinapis alba Unassigned Food Plant Sinapis Sin a 2.01 11S globulin 523 62240392 White mustard Sinapis alba Sin a 3.0101 Food Plant Sinapis Sin a 3.01 LTP 92 156778059 White mustard Sinapis alba Sin a 4.0101 Food Plant Sinapis Sin a 4.01 profilin 131 156778061 Whiteface hornet Dolichovespula maculata Dol m 1.02 Venom or Dolichovespula Dol m 1 Phospholipase A1B 303 1709542 Whiteface hornet Dolichovespula maculata Dol m 1.0101 Venom or Dolichovespula Dol m 1 Phospholipase A1B 317 288917 Whiteface hornet Dolichovespula maculata Dol m 2.0101 Venom or Dolichovespula Dol m 2 Hyaluronidase 331 511604 Whiteface hornet Dolichovespula maculata Dol m 5.0101 Venom or Dolichovespula Venom allergen 5 227 156715 Whiteface hornet Dolichovespula maculata Dol m 5.02 Venom or Dolichovespula Venom allergen 5 212 552080 Whiteleg Shrimp Litopenaeus vannamei Lit v 4.0101 Food Animal Litopenaeus Lit v 4 sarcoplasmic Ca+ binding 193 223403273 Whiteleg Shrimp Litopenaeus vannamei Lit v 1.0101 Food Animal Litopenaeus Lit v 1 tropomyosin 284 170791252 Whiteleg Shrimp Litopenaeus vannamei Lit v 2.0101 Food Animal Litopenaeus Lit v 2 356 115492980 Whiteleg Shrimp Litopenaeus vannamei Lit v 3.0101 Food Anima Litopenaeus Lit v 3 myosin 177 184198734 Wild Kiwi Actinidia eriantha Unassigned Food Plant Actinidia eriantha kiwellin 213 441482356 Wild Kiwi Actinidia eriantha Unassigned Food Plant Actinidia eriantha kiwellin 213 441482358 Wild Kiwi Actinidia eriantha Unassigned Food Plant Actinidia eriantha kiwellin 213 441482360 wolfberry Lycium barbarum Unassigned Food Plant Lycium Itp 51 363805423 Wrinked Neptune Neptunea polycostata Unassigned Food Animal Neptunea tropomyosin 284 219806590 Yak Bos grunniens mutus Bos d 11.0101 Food Animal Bos Bos d 11 beta casein 224 555980347 Yeast Candida albicans Cand a 1.0101 Contact Candida Cand a 1 Alcohol dehydrogenase 350 608690 Yeast Candida albicans Cand a 3.0101 Contact Candida Cand a 3 Peroxysomal protein 236 37548637 Yeast Candida albicans Unassigned Contact Candida Enolase 1 440 232054 Yeast Malassezia furfur Mala f 2 Contact Malassezia Mala f 2 177 3445490 Yeast Malassezia furfur Mala f 3 Contact Malassezia Mala f 3 166 3445492 Yeast Malassezia furfur Mala f 4 Contact Malassezia Mala f 4 342 4587985 Yeast Malassezia sympodialis Mala s 1 Contact Malassezia Mala s 1 350 1261972 Yeast Malassezia sympodialis Mala s 10.0101 Contact Malassezia Mala s 10 heat shock protein 773 28564467 Yeast Malassezia sympodialis Mala s 11 Contact Malassezia Mala s 11 first 38 aa signal 237 28569698 Yeast Malassezia sympodialis Mala s 12.0101 Contact Malassezia Mala s 12 618 78038796 Yeast Malassezia sympodialis Mala s 5 Contact Malassezia Mala s 5 172 4138171 Yeast Malassezia sympodialis Mala s 6 Contact Malassezia Mala s 6 162 4138173 Yeast Malassezia sympodialis Mala s 7 Contact Malassezia Mala s 7 187 4138175 Yeast Malassezia sympodialis Mala s 8 Contact Malassezia Mala s 8 179 7271239 Yeast Malassezia sympodialis Mala s 9 Contact Malassezia Mala s 9 342 19069920 Yeast Malassezia sympodialis ATCC 42132 Unassigned Contact Malassezia Mala s 10 heat shock protein 773 465797105 Yeast Malassezia sympodialis ATCC 42132 Unassigned Contact Malassezia Mala s 11 first 38 aa signal 202 465795607 Yeast Malassezia sympodialis ATCC 42132 Mala s 13 Contact Malassezia Mala s 13 Thioredoxin Rev 107 465793078 Yeast Malassezia sympodialis ATCC 42132 Unassigned Contact Malassezia Mala s 5 172 465794772 Yeast Malassezia sympodialis ATCC 42132 Unassigned Contact Malassezia Mala s 9 342 465794420 Yellow fever mosquito Aedes aegypti Aed a 1 Venom or Aedes Aed a 1 apyrase 562 556272 Yellow fever mosquito Aedes aegypti Unassigned Venom or Aedes Aed a 1 apyrase 562 193806340 Yellow fever mosquito Aedes aegypti Aed a 2 Venom or Aedes Aed a 2 321 205525919 Yellow fever mosquito Aedes aegypti Aed a 3 Venom or Aedes Aed a 3 253 2114497 Yellow fever mosquito Aedes aegypti Unassigned Venom or Aedes Aed a 3 273 94468546 Yellow jacket Dolichovespula arenaria Dol a 5.0101 Venom or Dolichovespula Venom allergen 5 203 156719 Yellowfin tuna Thunnus albacares Thu a 2.0101 Food Animal Thunnus Thu a 2 enolase 432 385145178 Yellowfin tuna Thunnus albacares Unassigned Food Animal Thunnus Thu a 2 enolase 12 576011132 Yellowfin tuna Thunnus albacares Unassigned Food Anima Thunnus Thu a 3 aldolase 364 291195949

(68) As used herein, the term about is used to refer to an amount that is approximately, nearly, almost, or in the vicinity of being equal to a stated amount, e.g., the state amount plus/minus about 5%, about 4%, about 3%, about 2%, or about 1%.

(69) The term patient or subject as used herein in reference to individuals who are being tested for the potential to produce an allergic response to an allergen and can encompasses veterinary uses, such as, for example, the testing of a rodent (e.g. a guinea pig, a hamster, a rat, a mouse), rabbit, murine (e.g. a mouse), canine (e.g. a dog), feline (e.g. a cat), equine (e.g. a horse), bovine (e.g., cow) a primate, simian (e.g. a monkey or ape), a monkey (e.g. marmoset, baboon), an ape (e.g. gorilla, chimpanzee, orangutan, gibbon). In preferred embodiments the mammal is a human.

(70) Other aspects and embodiments of the invention provide the aspects and embodiments described above with the term comprising replaced by the term consisting of and the aspects and embodiments described above with the term comprising replaced by the term consisting essentially of.

(71) As used herein, and/or is to be taken as specific disclosure of each of the two specified features or components with or without the other. For example A and/or B is to be taken as specific disclosure of each (i) A, (ii) B and (iii) A and B, just as if each is set out individually.

(72) It is to be understood that the application discloses all combinations of any of the above aspects and embodiments described above with each other, unless the context demands otherwise. Similarly, the application discloses all combinations of the preferred and/or optional features either singly or together with any of the other aspects, unless the context demands otherwise.

(73) The device of present invention is to derive simultaneous biological information on a variety of specific and nonspecific factors for risk of acute allergy from a single mammalian (including human) biological sample, such as a whole blood sample. In this situation, the blood sample will be acquired via a simple lancet skin pinprick or phlebotomy blood draw and analyzed by the microfluidic chip described herein, and the results will be integrated into a predictive algorithm that can accurately assess the current risk of acute allergic reactions to foods and/or drugs.

(74) The chip can be employed in conjunction with antibodies specific for cell-derived biological markers including: total and allergen specific IgG & IgE, histamine, cytokines such as IL-2, IL-4 and IL-13, tryptase, and LTC4. The antibodies can be conjugated with fluorescent dyes to produce a fluorescent signal upon binding to an antigen in the blood sample, or the antibodies can be detected in other ways, including surface plasmon resonance, bead-based solid phase detection, or colorimetric absorbance methodologies.

(75) Utilizing this method, type I hypersensitivity reactions can be tested within 3 to 6 hours after the injection of the blood sample onto the chip and type IV hypersensitivity reactions within about 72-96 hours after the injection of the blood sample onto the microfluidic chip, with CO.sub.2, O.sub.2, and pH parameters regulated to match in vivo conditions and maintain cell viability. In preferred embodiments, the chip described herein will have greater than 99% sensitivity and specificity with our laboratory diagnostic solution, making this the gold standard for allergy diagnostics in the future-able to both diagnose allergies to antigens as well as possibly predict the severity of the allergic reaction.

(76) As the technique and test will be conducted ex vivo, the patient will be protected from direct exposure to any allergens and the test will carry no risk of medical morbidity or mortality such as from anaphylaxis, making the test safe for all patients of all ages and for all allergy severities.

(77) All publications, patents and patent applications cited herein, whether supra or infra, are hereby incorporated by reference in their entirety for all purposes.

(78) This invention includes technological steps to implement an incubation chamber and a readout chamber as shown in FIG. 1. The microbeads pretreated with different conditions fill the center channels 10 in the bottom layer of the first section A as shown in FIG. 2 via the inlet 2 that leads the microbeads to the entrances 6 of the center channels 10 in the bottom layer. The blood sample fills the outer channel 9 of the first section A via the inlet 1. The microbeads are incubated in the first section and moved to the next section B via the exits 7 that merge to the bridge 4 for washing. The washing solution is introduced to the outer channels to wash the microbeads by either continuous flow or pulsatile flow via the inlet 1 of the section B in the same manner as described for the section A. The blood samples are discarded via the exit 3 of the incubation chamber A. Once washing is finished, the microbeads 11 are moved to the inlet 12 of the readout chambers C where they are captured in the evenly spaced seats 13 for further signal analysis as shown FIGS. 1, 5, and 6. When the seats are evenly spaced, the inventors unexpectedly found that signal interference from overlapping or conglomerated beads is reduced, which is a typical issue of multiplexed readout methodologies. The washing solution is discarded via the outlet 3 of the washing chamber. The modular structure of these chambers allows additional units consisting of A, B, and C to be added for duplicate or triplicate on chip analysis. This allows potentially an unlimited number of allergens or conditions to be tested simultaneously on chip.

(79) The outer channel 9 and the center channel 10 are separated by micro-pillars 8 as shown in FIG. 4, to prevent direct mixing of substances in the two channels but to allow mixing by diffusion. Due to this separation, the red blood cells and microbeads, for example, are not intermingled so that an additional extraction process of microbeads is unnecessary downstream. The microbeads can be either in the center channel 10 or outer channel 9 depending on the device configuration and application.

(80) The readout chamber can have two different formats such as one-way chamber shown in FIGS. 5, 6, 7 and two-way chamber shown in FIGS. 8, 9, 10.

(81) A one-way readout chamber is composed of evenly spaced seats 13 and flow guides 14. Because the shortest path to the outlet shown in FIG. 5 is dependent on the location of the outlet 5, the path toward left bottom has a smaller hydrodynamic resistance.

(82) The principle of the one-way readout chamber is based on the hydrodynamic relationship between the seats 13. The hydrodynamic resistance through the first empty seat R1 is smaller than the hydrodynamic resistance through the second empty seat R2 due the flow direction determined by the flow guide 14. Thus, the next microbead will sit in the first empty seat. In this way, all empty seats will be taken in sequence automatically without missed microbeads as shown in FIG. 7. The hydrodynamic resistance makes sure the empty seat closest to the inlet will be taken first.

(83) The two-way readout chamber is composed of evenly spaced seats 13 and a microvalve 15 instead of the flow guide. The microvalve 15 changes the flow direction dynamically so that the shortest path to the outlet 5 can be switched accordingly. The hydrodynamic relationship between the seats for the two-way readout chamber is same as that for the one-way readout chamber. Once the odd rows are filled, the microvalve 15 changes the flow direction to fill the even rows as shown in FIG. 9.

(84) The bi-well insert, shown in FIGS. 13, 14, 15, and 16 contains a porous vertical fluidic barrier. The insert maybe placed into a microwell in order to divide the well into two chambers. The fluidic barrier will prevent cells from crossing between the chambers while allowing diffusion of soluble molecules such as proteins. Preferably, the fluidic barrier pore size will be between 0.1 and 6 microns.

EXAMPLES

Example 1. Microfluidic Chip Material

(85) The microfluidic chip will be fabricated from a polymer such as (poly) dimethylsiloxane (PDMS) and glass, although we will consider using COC or PTE film instead of PDMS and glass to reduce the cost of material for mass production. All fluidic channels will be embedded into the PDMS material via common soft lithography manufacturing processes (e.g. according to the previously published protocol (Selimovi et al., 2009).

Example 2. Microfluidic Chip Fabrication and Structure

(86) The following description is one of multiple possible chip designs. This description is only included for context, to visualize how the fluids (sample, reagents, and microbeads) will be routed on-chip and how the output (presence or absence of an immunological reaction) will be read out.

(87) The chip will be created by molding it to photoresist patterns on silicon wafers. The device will then be assembled from three adjacent fluidic layers: two fluidic (channel/chamber) layers and one control layer, such that the channel layers guides fluids (blood) to the assay chambers (where reactions of interest take place), and microvalves on the control layer can be activated to close off all chambers from the fluidic channels. (The rough fabrication protocol for such microvalves can be found in Selimovi et al., 2009). FIG. 4 shows the magnified view of a part of the chip. For simplicity, the control layer is not shown.

(88) The drawing in FIG. 4 also shows the micro-pillars as part of the incubation chamber, preventing direct mixing of substances in the two channels. The assembled microfluidic chip can be bonded to a sticky PET film or to a glass slide for stability and to avoid drying out of the device, since water that is present in the blood sample can permeate the PDMS layer. Alternatively, the bottom layer in FIG. 1 can also be made of glass. The choice of material for the bottom layer of the device has no bearing on the function and accuracy of the microfluidic chip.

(89) The following description only serves to explain the function and operation of the chip, with the understanding that a variety of channel and assay chamber dimensions on the microscale (below about 1000 micrometers, below about 900 micrometers, below about 800 micrometers, below about 700 micrometers, below about 600 micrometers, below about 500 micrometers, below about 400 micrometers, below about 300 micrometers, below about 200 micrometers, below about 100 micrometers, below about 50 micrometers, below about 10 micrometers, and/or below about 5 micrometers) can be used. The channels will have a low height compared to the width; at such aspect ratios the channels can easily be closed by a microvalve (on the control layer) activated at 20 psi or less.

(90) There is no limit on the maximum chamber size, as long as the following factors are considered: minimizing the reagent volume, minimizing the sample volume (blood), keeping the device confined to a size comparable to a 23 glass slide, so that it can be conveniently held in the hand during the blood collection from a finger prick, and keeping the aspect ratio of all features such that common (soft) lithography techniques can be used. Thus, chamber widths of up to 1000 micrometers can be used.

Example 3. On Chip Treatment of the Microbeads with Antibodies

(91) Instead of using pretreated microbeads, the microbeads can be pretreated on chip by adding a treatment section before the first section A shown in FIG. 1.

Example 4. Adding the Sample onto the Chip

(92) In one embodiment, the chip is delivered to the user with all allergens (food particles, drugs, and/or antibiotics) loaded onto the chip in a dry state and additional reagents will be added in an automated format. Alternatively, the additional reagents may be prepackaged on the chip as well. All incubation chambers will contain the same amount of antibiotic or other allergen at this stage. Assuming that the largest incubation chamber has a volume on the order of 10 nl, the total amount of blood necessary to run a single chip will be on the order of 1 microliter. A finger prick can provide a blood sample on the order of 50 microliters, while several milliliters of blood can be collected by drawing blood with a needle. Thus, both blood collection methods can supply enough blood for a single chip.

(93) When whole blood is utilized, the chip will contain lithium heparin or another anticoagulant that will mix with the patient's blood sample upon collection to prevent the blood from coagulating. Then, the mixed solution can be loaded onto the chip (Inlets for blood 1) either by using a hand-held plastic syringe (or a syringe pump) or via capillary flow of the blood from the finger stick. We envision applying only relatively low flow rates to distribute various fluids throughout the chip, so that only low pressures will be built up inside the microfluidic channels. To fully avoid building up pressure inside the chip, the liquids can be pulled through the chip (by applying negative pressure at any outlets (3, 5) instead of pushing the liquids (e.g. by using a pipette to introduce the blood sample into the chip). As the blood/coagulant solution flows into the microfluidic chip, it will displace any air previously present inside the fluidic channels and incubation chambers. When it reaches the incubation chambers, it will dissolve the dry drug/antibiotic or suspend the food allergens. The flow of the solution will be sufficiently slow to not flush the allergens from the chamber.

(94) The blood can be introduced through the inlet for blood 1 such that it reaches the outer channels 9. After enough incubation time, the solution or microbeads move to the next section and the blood exits through the outlet 3 and can be collected inside attached polyethylene tubing or simply allowed to collect on top of the ports and evaporate there.

Example 5. On-Chip Tests

(95) Preferably, each chip can provide a positive and a negative control, conducted, for example, in triplicate. For example, the chip can enable the simultaneous testing of up to 5 different allergens and 2 controls, each of those by analyzing the presence of at least 5 biomarkers in the blood, and each experiment being repeated in triplicate, the total number of assays conducted on the chip can be 105. Since in this example all incubation chambers are connected with channels only in one direction, the blood or coagulation solution flowing through one particular channel will only reach one particular allergen and only one particular set of antibodies and will not mix with other allergens or have access to other antibodies. In addition, each chip is a preferably single-use device to avoid cross-contamination and will be disposed of appropriately after the test is completed.

(96) In addition to allergy testing, other testing that could be performed on the microchips includes measuring blood counts, blood typing, and blood cross-matching. Blood typing could be performed by mixing the sample with antibodies against various blood groups and monitoring for an agglutination (clumping) reaction. Blood cross-matching could be performed by mixing an individual's blood with blood from one or more individuals to evaluate for agglutination or hemolysis.

Example 6. Analyzing the Sample

(97) Any required washing steps or introduction of additional reagents for enzyme-based assays will rely on injection of those solutions through the inlet of the second section B in FIG. 1.

(98) As part of the reaction between blood components and the allergens, particular biomarkers expressed in the blood will bind to the antibodies on the microbeads or surface of the incubation chamber. Washing steps will remove any unbound biomarkers and the allergen. Additional antibodies that bind to the marker of interest will then be introduced, and detection will be accomplished via fluorescence or colorimetric read-outs (depending on the substance conjugated to the detection antibodies). Hence, the reaction will have to occur in a dark chamber to avoid any potential bleaching effects. Each individual readout chamber can be evaluated under a fluorescence microscope or with a spectrophotometer to detect the presence or absence of bound biomarkers.

Example 7. Result Readout

(99) If a fluorescence microscope is used, a light-emitting diode (LED) will be used as an excitation source. We plan to employ UV, red, and other LEDs to excite the fluorophores conjugated to the antibodies (Randers-Eichhorn, Albano, Sipior, Bentley, & Rao, 1997). FIG. 11 details a possible imaging setup with the chip placed on a robotic xyz stage and underneath an objective. The camera can either be a CCD chip camera, or depending on the required resolution, a camera attached to a common smartphone, or a web-camera via an adapter. The camera will record the resulting fluorescence signals and save the data as image files. A proprietary algorithm (loaded as a mobile application onto a smartphone or a computer, for example) will then measure the intensity of the signal in each assay chamber and report those numbers to conclude whether an allergic reaction is present.

(100) An alternative to this optical read-out is presented by Chen et al., 2015. In this case, it is contemplated to pattern gold nanorods on the surface of all assay chambers and conjugate them with antibodies against the various antigens that are being interrogated. Data will be collected using localized surface plasmon resonance and the scattering intensity from the nanorods will be recorded for a sample in which no antigens are present and will be compared to the scattering intensity in our tests. The resulting spectrum shift will be used as a measure of an allergic reaction.

Example 8. Bead-Based Incubation Chamber

(101) The incubation chamber described as the first section of the device (A) can be used for incubation of red blood cells with pretreated microbeads by introducing the red blood cells into the outer channel and the microbeads into the center channel or vice versa.

(102) The incubation chamber described as the first section of the device (A) can also be used for incubation of antibody, allergen, or other substances to treat microbeads by introducing the substance into the outer channel and the microbeads into the center channel or vice versa.

(103) The incubation chamber described as the first section of the device (A) can also be used for incubation of microdrops with other substances by introducing the microdrops into the outer channel and the substances into the center channel or vice versa.

(104) The incubation chamber described as the first section of the device (A) can also be used for incubation of two or more substances by introducing the one substance into the outer channel and the second substance into the center channel or vice versa.

(105) The incubation chamber described as the first section of the device (A) can also be used for incubation of two or more cells by introducing one group of cells into the outer channel and another group of cells into the center channel or vice versa.

(106) The incubation chamber described as the first section of the device (A) can also be used to examine blood viscosity by adjusting the space between the micro-pillars and monitoring pressure profile while applying steady, impulse, pulsatile, or other forms of pressure input.

(107) The incubation chamber described as the first section of the device (A) can also be utilized for blood typing and serologic cross-matching by utilizing agglutination as tracked by image recognition paired with deep learning.

(108) The incubation chamber described as the second section of the device (B) can be used for washing of the treated microbeads by introducing the washing solution into the outer channel and the microbeads into the center channel or vice versa.

Example 9. Bead-Based Readout Chamber

(109) The seats in the readout chamber C separate beads and prevent bead overlap with even spacing. This allows discrete image processing via simple digital processing, and the accuracy of the readout result is greatly increased by avoiding noise and bias caused by bead overlap or close proximity, which is a typical issue of conventional multiplexed readout methodologies.

(110) The readout chamber C can also be used to capture red blood cells for incubation or treatment with antibody, allergen, nutrients, or other substances. Substances secreted by the cells can be continuously collected.

(111) The readout chamber C can also be used to capture microbeads for continuous treatment or reaction with antibody, allergen, or other substances while monitoring the change of signal. Because microbeads are monodispersed with a predetermined distance, quantitative analysis can be done without signal overlap

(112) The readout chamber C can also be used to capture microdrops for continuous treatment or reaction with antibody, allergen, or other substances while monitoring the change of signal, size, color, or any other properties.

(113) The readout chamber C can also be used to capture other cell types such as primary cells, cancer cells, or stem cells for applications such as identification of circulating tumor cells and culture, differentiation, or treatment with nutrients, differentiation factors, antibodies, allergens, drugs, or other substances. Changes in cell morphology, cytotoxicity, or levels of secreted substances can be measured.

(114) The readout chamber C can also be used to capture yeast cells for culture, treatment or reaction with nutrients, antibodies, allergens, drugs, or other substances while keeping the first generation cells, monitoring offspring cells, and collecting secreted substances.

(115) The readout chamber C can also be used to capture embryos or cloned embryos for culture, differentiation, treatment or reaction with nutrients, antibodies, allergens, drugs, or other substances while monitoring changes in cell morphology, cytotoxicity, or levels of secreted substances.

(116) The readout chamber C can also be used to capture oocytes for in-vitro fertilization, culture, differentiation, treatment or reaction with sperm, nutrients, antibodies, allergens, drugs, or other substances while monitoring the changes in cell morphology, cytotoxicity, or levels of secreted substances.

(117) The readout chamber C can also be used to capture small animals such as C-elegans for stimulation, treatment or reaction with nutrients, stimuli, antibodies, allergens, drugs, or other substances while monitoring for changes in morphology or levels of secreted substances

(118) The readout chamber C can also be used to capture two different types of cells, oocytes, embryos, microbeads, droplets, or animals for co-culture, comparison, or other simultaneous study

(119) The readout chamber C can also be used to measure cell density by counting the trapped cells.

(120) The readout chamber C can also be used to separate cells based on size and stained color by adjusting the size and shape of the microseats and controlling the flow path.

(121) The readout chamber can be used to capture single white blood cells in metaphase for karyotype analysis after appropriate treatment in the incubation A and wash B chambers.

(122) The readout chamber can be used to capture white blood cell fractions (such as neutrophils, basophils, eosinophils, lymphocytes, and monocytes) to generate an automated differential with the aid of image recognition paired with deep learning.

Example 10. Fabrication and Usage of the Bi-Well Insert

(123) Relying on the same fluid dynamics, the chip can be designed as microwells containing bi-well inserts. In this situation, the bi-well insert can be made of construction materials such as polystyrene, polycarbonate, COC, PTFE, and PDMS using injection molding, 3D printing, and other manufacturing processes. The vertical membrane can be attached to the bi-well insert by gluing or heat press.

(124) In this case, the bi-well insert divides a microwell into two chambers as described abovean incubation chamber (FIG. 13, number 17) and a washing/capture chamber (FIG. 13, number 18), both chambers having an inlet which also functions as an outlet.

(125) Once the bi-well insert is in place, microbeads are introduced in the microwell via the inlet of 18 into the washing/capture chamber and whole blood is filled into the incubation chamber via the inlet of 17. After a suitable incubation period the bi-well insert is removed and microbeads remaining in the microwell get washed.

(126) Microbeads will be transferred to the bead-based readout chamber described in example 9 or to a commercially-available multiplex bead analyzer.