The present disclosure relates to an organic electroluminescent compound and an organic electroluminescent device comprising the same. By comprising the organic electroluminescent compound according to the present disclosure in a hole transport zone, it is possible to produce an organic electroluminescent device having improved luminous efficiency and/or lifespan characteristics.

The present disclosure relates to an organic electroluminescent compound and an organic electroluminescent device comprising the same. By comprising the organic electroluminescent compound according to the present disclosure in a hole transport zone, it is possible to produce an organic electroluminescent device having improved luminous efficiency and/or lifespan characteristics.

The present invention relates to a compound for an organic optoelectronic device, represented by Chemical Formula 1; a composition for an organic optoelectronic device, including same; an organic optoelectronic device; and a display device. The description of Chemical Formula 1 is the same as that defined in the specification.

The present invention relates to a compound for an organic optoelectronic device, represented by Chemical Formula 1; a composition for an organic optoelectronic device, including same; an organic optoelectronic device; and a display device. The description of Chemical Formula 1 is the same as that defined in the specification.

Disclosed are a compound as shown in formula I or formula II or a pharmaceutically acceptable salt thereof, wherein R.sub.1 is selected from pyrazinyl or substituted pyrazinyl; and R.sub.2 is selected from pyrazinyl or substituted pyrazinyl, phenyl or substituted phenyl, alkyl or substituted alkyl.

The present disclosure relates to compounds having an improved solubility thereby increasing their bioavailability, lower dosages, etc. The target compounds, may include but are not limited to, macrophage migration inhibitory factor (MIF) inhibitors, epidermal growth factor receptor (EGRF) inhibitors, kinase inhibitors and prodrugs of alpha4 beta1 and alpha4 beta7 integrin antagonists. An illustrative compound is shown below: ##STR00001##

The present invention relates to iridium complexes suitable for use in organic electroluminescent devices, especially as emitters.

The invention relates to methods and intermediates useful in the synthesis of eribulin.

The present invention relates to a method of producing an improved asphalt. The method involves providing an asphalt and providing a compound of formula (I), as described herein. The asphalt is mixed with the compound of formula (I) under conditions effective to produce an improved asphalt. Also disclosed are an asphalt product and a method of making asphalt material. The invention further discloses a method of producing an improved asphalt comprising providing a polymer modified asphalt and providing a compound of formula (IIa) or formula (II). The polymer modified asphalt is mixed with the compound of formula (IIa) or formula (IIb) under conditions effective to produce an improved asphalt, which is yet another aspect of the present invention. ##STR00001##

The present invention relates to a method of producing an improved asphalt. The method involves providing an asphalt and providing a compound of formula (I), as described herein. The asphalt is mixed with the compound of formula (I) under conditions effective to produce an improved asphalt. Also disclosed are an asphalt product and a method of making asphalt material. The invention further discloses a method of producing an improved asphalt comprising providing a polymer modified asphalt and providing a compound of formula (IIa) or formula (II). The polymer modified asphalt is mixed with the compound of formula (IIa) or formula (IIb) under conditions effective to produce an improved asphalt, which is yet another aspect of the present invention. ##STR00001##