C07D263/00

NEW POLYOLEFIN CATALYST AND USE THEREOF
20170349675 · 2017-12-07 ·

Disclosed is a new polyolefin catalyst and preparation therefor. Specifically, disclosed is a catalytic system comprising a new complex of iron, cobalt, nickel, palladium, and platinum. In the presence of the catalytic system, oily polyethylene can be efficiently obtained from simple olefins such as ethylene under mild conditions, highly branched oily alkane mixture is then obtained after hydrogenation. The alkane mixture can be used as a processing aid and a high-performance lubricant base oil. The present invention also provides a method for preparing the catalyst, a method for preparing the highly branched oily alkane mixture and a method for preparing functional polyolefin oil.

Filtration process for purifying liquid azole heteroaromatic compound-containing mixtures

A process for removing impurities from a liquid azole heteroaromatic compound-containing (e.g., triazole-containing) mixture by: (a) providing a liquid azole heteroaromatic compound-containing mixture having impurities; and (b) passing the azole heteroaromatic compound-containing mixture through at least one filtration membrane which is a nanofiltration membrane and/or ultrafiltration membrane having a molecular pore size in the range of from about 200 daltons to about 1 kilodaltons to provide a permeate that is an at least partially purified azole heteroaromatic compound-containing mixture and a retentate with at least some impurities.

Polyolefin catalyst and use thereof

Disclosed is a new polyolefin catalyst and preparation therefor. Specifically, disclosed is a catalytic system comprising a new complex of iron, cobalt, nickel, palladium, and platinum. In the presence of the catalytic system, oily polyethylene can be efficiently obtained from simple olefins such as ethylene under mild conditions, highly branched oily alkane mixture is then obtained after hydrogenation. The alkane mixture can be used as a processing aid and a high-performance lubricant base oil. The present invention also provides a method for preparing the catalyst, a method for preparing the highly branched oily alkane mixture and a method for preparing functional polyolefin oil.

Polyolefin catalyst and use thereof

Disclosed is a new polyolefin catalyst and preparation therefor. Specifically, disclosed is a catalytic system comprising a new complex of iron, cobalt, nickel, palladium, and platinum. In the presence of the catalytic system, oily polyethylene can be efficiently obtained from simple olefins such as ethylene under mild conditions, highly branched oily alkane mixture is then obtained after hydrogenation. The alkane mixture can be used as a processing aid and a high-performance lubricant base oil. The present invention also provides a method for preparing the catalyst, a method for preparing the highly branched oily alkane mixture and a method for preparing functional polyolefin oil.

Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof

Certain compounds, or pharmaceutically acceptable salts or prodrugs thereof, are provided herein. Also provided are pharmaceutical compositions comprising at least one compound, or pharmaceutically acceptable salt or prodrug thereof, described herein and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of KMO activity are described, which comprise administering to such patients an amount of at least one compound, or pharmaceutically acceptable salt or prodrug thereof, described herein effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include neurodegenerative disorders such as Huntington's disease. Also described are methods of treatment include administering at least one compound, or pharmaceutically acceptable salt or prodrug thereof, described herein as a single active agent or administering at least one compound, or pharmaceutically acceptable salt or prodrug thereof, described herein in combination with one or more other therapeutic agents. Also provided are methods for screening compounds capable of inhibiting KMO activity.

Azide-functionalized copolymers

The present invention relates to a copolymer having several azide functionalities that can be prepared by cationic ring opening polymerisation. The copolymer comprises a first monomer unit and a second monomer unit which are different from each other.