A method of making alkenes and/or epoxides from alkanes and hydroxy-alkanes, respectively. In a reactor having an anode and a cathode separated by an ion exchange membrane, and containing a solution comprising water, halogen ions, and an alkane and/or a hydroxy-alkane, apply a potential across the anode and the cathode such that a halogenated intermediate is produced at the anode as an anolyte and hydroxyl ions are produced at the cathode as a catholyte; and combining the anolyte and the catholyte to yield an alkene and/or an epoxide.

Disclosed in the present invention are methods for the electrochemical generation of aqueous organic haloamine solutions from precursor solutions comprising at least one halide-containing salt, at least one organic amine component, and an acid additive. The described method allows for the production of aqueous organic haloamine solutions with compositions ranging from a single organic haloamine component to multiple organic haloamine components and multiple free halogen components and solutions with desired pH values.

A method for preparing a compound with a spiro[5.5] molecular skeleton by electrooxidation is provided, which relates to the field of organic synthesis technology. Specifically, the method includes o-alkynyl benzoyl biphenyl reacts with sodium fluoromethylsulfite in an electrolyte and a solvent under a current condition to obtain the compound with the spiro[5.5] molecular skeleton. The method uses cheap CF.sub.3 (trifluoromethyl) free radical and electrooxidation to realize the de-aromatization of biphenyl without catalyst. The reaction can occur only under the action of current, which is energy-saving and economical. The free radical used in the reaction is cheap, easy to obtain and low cost. The reaction device is simple and easy to operate, and the yield of the reaction is as high as 60%.

A method for preparing a compound with a spiro[5.5] molecular skeleton by electrooxidation is provided, which relates to the field of organic synthesis technology. Specifically, the method includes o-alkynyl benzoyl biphenyl reacts with sodium fluoromethylsulfite in an electrolyte and a solvent under a current condition to obtain the compound with the spiro[5.5] molecular skeleton. The method uses cheap CF.sub.3 (trifluoromethyl) free radical and electrooxidation to realize the de-aromatization of biphenyl without catalyst. The reaction can occur only under the action of current, which is energy-saving and economical. The free radical used in the reaction is cheap, easy to obtain and low cost. The reaction device is simple and easy to operate, and the yield of the reaction is as high as 60%.

This invention provides a catalytic process wherein alternating current is used for catalytic coupling (such as CC, CN, CO, CS, CP, CSi and/or CB couplings) using a transition-metal catalysis.

This invention provides a catalytic process wherein alternating current is used for catalytic coupling (such as CC, CN, CO, CS, CP, CSi and/or CB couplings) using a transition-metal catalysis.

The current disclosure provides alternating current based systems and methods to develop chemical compounds, such as drug molecules using electrochemistry in organic synthesis.

The current disclosure provides alternating current based systems and methods to develop chemical compounds, such as drug molecules using electrochemistry in organic synthesis.

Disclosed herein are methods and systems that relate to electrochemically oxidizing metal halide with a metal ion in a lower oxidation state to a higher oxidation state; halogenating an unsaturated hydrocarbon or a saturated hydrocarbon with the metal halide with the metal ion in the higher oxidation state; and oxyhalogenating the metal halide with the metal ion from a lower oxidation state to a higher oxidation state in presence of an oxidant. In some embodiments, the oxyhalogenation is in series with the electrochemical oxidation, the electrochemical oxidation is in series with the oxyhalogenation, the oxyhalogenation is parallel to the electrochemical oxidation, and/or the oxyhalogenation is simultaneous with the halogenation.

Disclosed herein are methods and systems that relate to electrochemically oxidizing metal halide with a metal ion in a lower oxidation state to a higher oxidation state; halogenating an unsaturated hydrocarbon or a saturated hydrocarbon with the metal halide with the metal ion in the higher oxidation state; and oxyhalogenating the metal halide with the metal ion from a lower oxidation state to a higher oxidation state in presence of an oxidant. In some embodiments, the oxyhalogenation is in series with the electrochemical oxidation, the electrochemical oxidation is in series with the oxyhalogenation, the oxyhalogenation is parallel to the electrochemical oxidation, and/or the oxyhalogenation is simultaneous with the halogenation.