Examples described herein may predict therapy efficacy and/or therapeutic parameters using a comparison of individual patient status data and brain network response maps for the therapy. For example, VNS parameters may be predicted using a comparison of patient EEG data and brain network response maps of VNS therapy at various parameters.

A wearable device consists of a smart band and a display unit. The smart band comprises a microbial biosensor, a particulate matter sensor, an enviro sensor, a single board computer, a power supply unit, a band fastener, and a set of watch adapters. The microbial biosensor detects, measures, and monitors beneficial microorganisms and pathogens in a nasal cavity, an oral cavity, or on a surface. The microbial biosensor sterilizer kills pathogens. The particulate matter sensor detects, measures, and monitors a set of suspended particles in the surrounding air comprising beneficial microorganisms, pathogens, pollen grains, dust mite allergens, and an air quality index. The enviro sensor detects, monitors, and measures environmental conditions surrounding the user. A computing system comprises a wearable device, a microbiome mobile application, a user, a mobile device, a laboratory testing facility, a cloud server, and a physician.

The present disclosure provides a method for determining an ultrasound focus location in a thermal image. In one aspect, the method includes obtaining a magnetic resonance thermal image of a tissue heated by a focused ultrasound and correcting a chemical shift and a k-space shift of a monitored ultrasound focus location in the magnetic resonance thermal image such that the monitored ultrasound focus location is aligned with a real physical ultrasound focus location. Correcting the chemical shift includes correcting a first spatial error of the monitored ultrasound focus location caused by resonance frequency changes of hydrogen nuclei due to environmental differences of water molecules. Correcting the k-space shift includes correcting a second spatial error of the monitored ultrasound focus location caused by temperature error due to spatial variations of a primary magnetic field.

A system for estimating a distance between vehicles may include an oscillator, a transmitter, a receiver, a summing circuit, a signal analyzer, a tunable phase shifter, a distance estimator, and/or a vehicle identifier. The oscillator may generate a generated oscillating signal, transmitted by the transmitter. The receiver may receive a processed signal derived by a system of a second vehicle. The summing circuit may add the generated oscillating signal to the received signal to produce the updated oscillating signal. The signal analyzer may detect a spike in amplitude associated with the updated oscillating signal. The tunable phase shifter may shift a phase of the generated oscillating signal by an incremental phase shift amount until a spike in amplitude is detected. The distance estimator may estimate the distance between the first vehicle and the second vehicle based on a total phase shift amount and the predetermined wavelength.

A system and method for imaging an anatomical structure corresponding to an infusion therapy anatomical site includes a processor to execute applications stored in a non-transitory computerreadable medium, the applications includes a first application to receive imaging information corresponding to radiant energy from the infusion therapy anatomical site, a second application to decompose the received imaging information into discrete image components, a third application to receive at least one of patient biographic profile characteristics and infusion therapy parameters, and a fourth application to receive the discrete image components, the patient biographic profile characteristics and the infusion therapy parameters and to provide a recommended clinical intervention based on at least one of the discrete image components, the patient biographic profile characteristics, and the infusion therapy parameters.

Disclosed herein are methods of vascular and structural imaging using imaging systems and methods described, the methods comprising producing an image of the vasculature or structure by imaging fluorescence using an imaging system, the system comprising: i) one or more detectors configured to form a fluorescence image of the sample and form a visible image of the sample; ii) a light source configured to emit an excitation light to induce fluorescence from the sample; and iii) a plurality of optics arranged to: direct the excitation light toward the sample; and direct a fluorescent light and a visible light from the sample to the detector; wherein the excitation light and the fluorescence light are directed substantially coaxially.

Disclosed is a medical system (100, 500) that comprises a radiotherapy system (102) configured for controllably irradiating a target volume (114) within an irradiation zone (112); a subject support (120) configured for supporting at least a ventral region (124) of a subject (122) within the irradiation zone; a breath monitor system (132, 132′) configured for providing a motion signal (154, 158) descriptive of subject breathing motion; and a subject display (130, 130′) configured for displaying a breathing phase indicator (160, 160′) to the subject when supported by the subject support. Execution of the machine executable instructions (150) causes a processor (142) controlling the medical system to receive (200) a time resolved magnetic resonance imaging dataset (152) synchronized to a measured motion signal (154). Execution of the machine executable instructions further causes the processor to repeatedly: determine (202) a desired motion signal (156) by temporally stepping through the measured motion signal; acquire (204) a current motion signal (158) using the breath monitor system; render (206) the breathing phase indicator on the display, wherein the breathing phase indicator is configured to indicate a difference (700) between the desired motion signal and the measured motion signal; and generate (208) control commands (162) configured for controlling targeting of the radio therapy system using a first portion of the time resolved magnetic resonance imaging dataset synchronized to the desired motion signal or a second portion of the time resolved magnetic resonance imaging dataset referenced by the current motion signal.

Systems and methods for real-time target validation during radiation treatment therapy based on real-time target displacement and radiation dosimetry measurements.

Disclosed are a method of measuring concentration distribution of boron for boron neutron capture therapy (BNCT) using magnetic resonance imaging (MRI) alone and a treatment planning method for BNCT. The methods include (a) acquiring an anatomical image of a patient and measuring a boron concentration from magnetic resonance (MR) data, (b) extracting a boron concentration change prediction parameter of the patient and predicting the concentration over time, (c) calculating and verifying a boron distribution prediction value estimated by boron imaging and spectral analysis, and (d) deriving an optimal time for BNCT based on the verified results.

Systems configured to acquire temperature signals from an Abreu Brain Thermal Tunnel (ABTT), to analyze the temperatures signals, and to determine a condition of a human body from the analysis, and a method for doing the same, are described. In addition, systems for application of thermal signals to the ABTT for treatment of conditions are described.