An intraoral imaging apparatus, a medical apparatus, and a program capable of providing auxiliary data for determination regarding diseases having differences in intraoral findings are provided. The intraoral imaging apparatus includes: an imaging device that acquires an intraoral image; a light source that emits light to a subject of the imaging device; a storage apparatus that stores an algorithm for performing determination of a specific disease; and an arithmetic apparatus, in which the arithmetic apparatus executes: a determination process of determining a possibility of the predetermined disease based on the image and the algorithm; and an output process of outputting a result of the determination process.

A portable system to be inserted within the birth canal for measuring dilation of a cervical region is disclosed. The system comprises a housing having a first portion sized to conform to a user's hand thereby defining a handle and a second portion sized to be inserted into the birth canal. The system includes two structured light sources configured to project a pattern onto the cervical region, a sensor, a trigger interface, a power source, and the processor configured for capturing image sensor data. The processor is configured for receiving image data from the sensor, processing the image sensor data, calculating a measurement of the dilation of the cervical region, and transmitting the data. The processor will transmit the data onto the display, presenting the measurement of dilation as well as a visual representation of the measurement.

This disclosure provides a method for imaging lymph nodes and lymphatic vessels without a contrast agent. The method includes providing, using an optical source, an infrared illumination to a region of a subject having at least one lymphatic component, detecting a reflected portion of the infrared illumination directly reflected from the region using a sensor positioned thereabout, and generating at least one image indicative of the at least one lymphatic component in the subject using the reflected portion of the infrared illumination.

For volumetric analysis of the elemental composition of a measured sample (3) the method of three-dimensional scanning is executing using fluorescence induced by electromagnetic radiation, in which the primary beam (1) of electromagnetic radiation is flattened and is directed at the measured sample (3) in which it irradiates the measured area (6). From the measured area (6) there exits fluorescence radiation, which is almost completely shielded by the shielding means (7) to a secondary beam (9), which is released towards the shielded detector (4) through the permeable area (8) formed in the shielding means (7). The secondary beam (9) projects the image of the measured area (6) onto the shielded detector (4), which records the data of the measured area (6) and subsequently uses the data to obtain an elemental composition of the measured sample (3), including the distribution of concentration of elements in the sample volume.

Exemplary apparatus for method for forming at least one spectral encoding endoscopy configuration. For example, it is possible to modify a spacer configuration and an lens optics configuration to have respective predetermined lengths, and also to modify a dispersive optics configuration to have a further predetermined length. Further, the modified spacer and modified lens optics configurations can be attached to one another to form a combined spacer-lens optics configuration. The modified dispersive optics configuration can be attached to a substrate to form to form a grating substrate configuration. Additionally, the combined spacer-lens optics configuration can be connected to an optical fiber, and the modified attached dispersed optics configuration can be connected to the modified attached lens optics configuration to form the spectral encoding endoscopy configuration(s) which can extends along a particular axis. The dispersive optics configuration can be modified to be at a predetermined angle with respect to the particular axis.

A subject information acquisition apparatus comprises a casing in which a transmissive member capable of transmitting acoustic waves and laser beams therethrough is provided; a light irradiating unit disposed inside the casing so as to irradiate a subject with laser beams with the transmissive member interposed; an acoustic wave probe disposed inside the casing so as to receive acoustic waves with the transmissive member interposed; and a scanning mechanism disposed inside the casing so as to move the light irradiating unit and the acoustic wave probe in relation to the casing, wherein the casing is configured to be movable on the subject.

A method of generating corrected fluorescence data of concentrations of a targeted fluorophore in tissue of a subject includes administering first and second fluorescent contrast agents to the subject, the first contrast agent targeted to tissue of interest, the second agent untargeted. The tissue is illuminated with light of a first stimulus wavelength and first data is acquired at an appropriate emissions wavelength; the tissue is illuminated at a second stimulus wavelength and second data is acquired at a second emissions wavelength associated with the second agent, the first and second emissions wavelength differ. Difference data is generated by subtracting the second data from the first data. A system provides for stimulus and capture at multiple wavelengths, with image storage memory and subtraction code, to perform the method. Corrected data may form an fluorescence image, or is used to generate fluorescence tomographic images.

A method of generating corrected fluorescence data of concentrations of a targeted fluorophore in tissue of a subject includes administering first and second fluorescent contrast agents to the subject, the first contrast agent targeted to tissue of interest, the second agent untargeted. The tissue is illuminated with light of a first stimulus wavelength and first data is acquired at an appropriate emissions wavelength; the tissue is illuminated at a second stimulus wavelength and second data is acquired at a second emissions wavelength associated with the second agent, the first and second emissions wavelength differ. Difference data is generated by subtracting the second data from the first data. A system provides for stimulus and capture at multiple wavelengths, with image storage memory and subtraction code, to perform the method. Corrected data may form an fluorescence image, or is used to generate fluorescence tomographic images.

An intra-oral scanning device includes a light source and an optical system, and communicates with a display system. The device has a reduced form factor as compared to prior devices, and it provides for more efficient transmission and capture of images.

Fourier Transformation Spectrometer, FT Spectrometer, comprising: Michelson-Type Interferometer (601, 602, 603, 604, 605, 606, 607, 608, 609) comprising: at least one beam splitter unit designed to split an incident light beam (EB) of a spatially expanded object into a first partial beam (TB1) and a second partial beam (TB2); and for at least partially overlaying the first partial beam (TB1) and the second partial beam (TB2) with a lateral shear (s); a first beam deflection unit designed to deflect the first partial beam (TB1) at least once; a second beam deflection unit designed to deflect the second partial beam (TB2) at least once; wherein at least one among the first beam deflection unit and the second beam deflection unit represents a (2n+1) periscope group with (2n+1) mirror surfaces, and all (2n+1) mirror surfaces are arranged vertically in relation to a common reference plane, in order to respectively deflect the first partial beam (TB1) and/or the second partial beam (TB2) (2n+1) times, and wherein the (2n+1)-fold deflection generates the lateral shear (s) between the first partial beam (TB1) and the second partial beam (TB2), and wherein n is a natural number ≥1.