A system and method for compensation of angular distortions in a system utilizing light emitters and light sensors disposed on non-parallel jaws may include determining a first point at a first side of a region of interest and a second point at a second side of the region of interest, determining a linear curve including the first and second points, and utilizing the linear curve to remove the angular distortion from the region of interest between the first and second points. A system and method for compensation of angular distortions may alternatively include modeling a non-pulsatile illumination pattern according to the intensities of individual emitters, comparing the pattern according to the model against a non-pulsatile illumination pattern detected using the light sensors, and varying the intensities of the individual emitters based on the comparison until angular distortion has been removed.

A device and system for non-invasively measuring wavelength-dependent changes in optical absorption of brain tissue damaged by CTE, TBI, concussion, repetitive trauma, and/or Lou Gehrig’s disease in comparison to signals from healthy normal tissue for a subject in vivo. The brain, tissues, and fluids superficial to the brain are trans-cranially illuminated by light source(s) in low-absorption spectral windows for tissue in the visible and/or near-infrared parts of the spectrum. Optode(s) are disposed at predetermined radial distance(s) from a light output to collect the scattered and/or deflected signal from the surface of the head. The predetermined radial distance from the light output to the optode is correlated with the depth of tissue penetration for the light collected by the optode. A spectrometer and computer analyze the collected light for characteristic optical signatures of the brain tissue damage utilizing the absorbance and/or reflectance and/or transmission spectra generated as a result.

Systems and methods for administering one or more hydration compositions to an individual to improve vascular health are provided. A system comprises a hydration composition delivery element and a sensor operatively coupled to the hydration composition delivery element. The sensor is configured to determine one or more of the intake of fluids, the amount of fluid discharged, the activity level of the patient, or level of hydration of the patient based on the level of fluid in the hydration composition delivery element. The system further includes a monitoring system which, based on a signal received from the sensor, provides an indication of one or more of the need to intake fluid, the identity of a specific hydration composition of a plurality of hydration compositions to be consumed or an amount of a hydration composition to be consumed.

The invention provides a system and method for measuring vital signs and motion from a patient. The system features: (i) first and second sensors configured to independently generate time-dependent waveforms indicative of one or more contractile properties of the patient's heart; and (ii) at least three motion-detecting sensors positioned on the forearm, upper arm, and a body location other than the forearm or upper arm of the patient. Each motion-detecting sensor generates at least one time-dependent motion waveform indicative of motion of the location on the patient's body to which it is affixed. A processing component receives the time-dependent waveforms generated by the different sensors and processes them to determine: (i) a pulse transit time calculated using a time difference between features in two separate time-dependent waveforms, (ii) a blood pressure value calculated from the time difference, and (iii) a motion parameter calculated from at least one motion waveform.

A wearable sensing band is presented that generally provides a non-intrusive way to measure a person's cardiovascular vital signs including pulse transit time and pulse wave velocity. The band includes a strap with one or more primary electrocardiography (ECG) electrodes which are in contact with a first portion of the user's body, one or more secondary ECG electrodes, and one or more pulse pressure wave arrival (PPWA) sensors. The primary and secondary ECG electrodes detect an ECG signal whenever the secondary ECG electrodes make electrical contact with the second portion of the user's body, and the PPWA sensors sense an arrival of a pulse pressure wave to the first portion of the user's body from the user's heart. The ECG signal and PPWA sensor(s) readings are used to compute at least one of a pulse transit time (PTT) or a pulse wave velocity (PWV) of the user.

This document describes assessing cardiovascular function using an optical sensor, such as through sensing relevant hemodynamics understood by pulse transit times, blood pressures, pulse-wave velocities, and, in more breadth, ballistocardiograms and pressure-volume loops. The techniques disclosed in this document use various optical sensors to sense hemodynamics, such as skin color and skin and other organ displacement. These optical sensors require little if any risk to the patient and are simple and easy for the patient to use.

A non-invasive system and method are provided. Brain activity of a user is detected using a non-invasive brain interface when the user is exposed to an external stimulus. The user is determined to be negatively primed by the external stimulus based on the detected brain activity. An alert that the user is being negatively primed by the external stimulus is automatically provided. A tagged training session may be automatically provided to the user in response determining that the user has a negative mental state, thereby promoting a positive mental state of the user. A training session list containing the tagged training session may be automatically modified based on the determined mental state of the user.

There is provided a system and methods for quantitatively assessing fetal well-being based on observing fetal movement activity in an audio/visual data feed. The system includes a method that detects and quantifies fetal movements in an audio/visual data feed by audio/visual-processing motion estimation techniques. The system also includes a method that captures metrics relating to fetal movements sensed by the mother or other independent party, whereby termed “maternal perception”. The system further includes a method that cross validates the fetal movement detected by the system with fetal movement sensed by “maternal perception”. The system further includes a method that generates output to summarize fetal movement activity over a recorded time period. This output may be reviewed by a third party to assist in determining if further intervention is needed.

A method of generating a measurement of anatomy of interest from two-dimensional imaging includes receiving two-dimensional imaging associated with anatomy of interest; detecting a plurality of anatomical features of the anatomy of interest in the two-dimensional imaging using at least one machine learning model; determining characteristics of the plurality of anatomical features based on the detection of the plurality of anatomical features; and generating at least one measurement of the anatomy of interest based on at least some of the characteristics of the plurality of anatomical features.

Data derivable from remotely detected electromagnetic radiation (16) emitted or reflected by a subject (12) is processed. The data includes physiological information. An input signal is received and indicative entities are transmitted. The indicative entities being indicative of physiological information representative of at least one vital parameter (17; 150) in a subject (12) of interest, wherein the indicative entities are detected under consideration of at least one defined descriptive model (114) describing a relation between physical skin appearance characteristics and a corresponding representation in the input signal such that non-indicative side information represented by non-indicative entities in the input signal is substantially undetectable in a resulting transmitted signal. The at least one vital parameter (17; 150) is detected from the transmitted signal including the indicative entities. The at least one vital parameter (17; 150) is extracted under consideration of detected skin color properties representing circulatory activity.