A breath analyzer, a system, and a computer program for administering a breath analysis to a donor and recording a breath analysis result. Embodiments of the invention authenticate that the breath analysis was performed correctly, preserves the breath analysis results by communicating with other devices, and presents the breath analysis results by superimposing them on recorded video data. The breath analyzer includes a breath receptor for receiving a breath sample from the donor, an analyzing element for determining a breath analysis result, a communications element for sending information indicative of the breath analysis result to a recording device manager, and a housing for securing the components in a handheld device. The system comprises the breath analyzer, a recording device manager for synchronizing the recordings, and at least one ancillary camera for recording the breath analysis.

A device for measuring a concentration of a component in a target sample includes a flow chamber with a first channel that receives a reference sample having a known concentration of the component. The flow chamber also includes a second channel that receives the target sample having an unknown concentration of the component. A pump operates to pump the reference sample and the target sample at a same volume flow rate through the first and second channels, respectively. A thermal mass flow meter measures a thermal conductivity of the reference sample, a thermal conductivity of the target sample, or both.

A method of providing safety in a level 3 autonomous vehicle by mounting a plurality of cameras in a vehicular cabin to detect edges; translating the edges into motions of a human or a biological entity; and monitoring safety conditions for the human or biological entity.

A method of determining if a subject has a mild cognitive impairment (MCI) or Alzheimer's Disease, the method comprising measuring the concentration of one or more VOCs in an exhaled sample from a subject, and comparing the concentration with a reference concentration, I.

An apparatus for detecting Covid-19 infection in a subject, the apparatus comprising (a) a sampling apparatus for collecting a breath sample from a subject (b) An analyzer, comprising an ion mobility spectrometer (IMS), for receiving the sample from the sampling apparatus and for determining the presence in the sample of Volatile Organic Compounds (VOCs) indicative of Covid-19, the VOCs comprising at least three compounds selected from the group consisting of C1-C3 alcohols, C2-C8 aldehydes, C3-C4 ketones and C4-C6 alkyl esters.

Methods and devices to capture and analyze aerosolized particles such as protein biomarkers and their truncated proteoforms characteristic of a disease, including a respiratory disease, in exhaled breath to enable rapid detection of diseases are disclosed. The disclosed methods and systems selectively capture aerosolized particles using a packed bed column. The captured particles are then eluted using one or more solvents and analyzed using devices including mass spectrometry.

A method for synchronizing data for gas samples with volatile organic compounds. The data includes chromatographic data indicative of molecule retention times. The method includes identifying or selecting marker molecules and clustering the plurality of gas samples into a plurality of clusters according to a clustering criterion. Next, a first correction of retention time deviations is performed on the data for the gas samples between clusters by using the marker molecules as anchor points to provide a coarse reduction of retention time deviations between the data. Finally, a second correction of retention time deviations is performed on the data, so as to further reduce retention time deviations between the data. The method reduces significant retention time deviations to allow, e.g., breath sample fingerprints obtained by different equipment at different times to be compared in one database for use on a digital platform.

The present invention is directed to system and method for effectively monitoring critical respiratory parameters including SpO.sub.2, PR, COHb, inspired CO.sub.2, expired CO.sub.2, respiration rate, respiration pattern, hyperventilation (hypocapnia), hypoventilation (hypercapnia), CO.sub.2 contamination, and CO.sub.2 rebreathing. The system according to the present invention comprises a pulse oximetry sensor and a CO.sub.2 sensor connected to a central portable unit. The central unit comprising a barometer, an accelerometer, a capnography circuit, and a control unit. The control unit including the method for effectively monitoring critical respiratory parameters.

A system operable to determine a future point of time, at which the alcohol concentration in blood of a user is less than a threshold value. The system includes an alcohol sensor operable to detect a current alcohol concentration in blood of the user, and a portable apparatus. The alcohol sensor and the portable apparatus each comprise a wireless communication apparatus. The wireless communication apparatus in the alcohol sensor is operable to wirelessly transmit the current alcohol concentration to the wireless communication apparatus in the portable apparatus.

A hybrid gas sampling device can combine the functionality of both whole air and sorbent based samplers. The sampling device can be used for collecting light to very heavy organic compounds, for subsequent thermal desorption into a GC or GCMS for quantitative measurement. The sampling device isolates collected samples of gas phase matrices in a sample vessel, provided with sorbent elements from a removable sample extraction device. The sampling device is operated by drawing a vacuum on the chamber through the sample extraction device after sampling, and then completing the extraction of the heavier organic compounds using a static, diffusive extraction under vacuum to allow optimal deposition of the heavier compounds on the sorbent. The vacuum container is cooled to draw any excess water back into the container, thereby dehydrating attached sorbent element(s) in preparation for thermal desorption into a GC or GCMS, eliminating interferences in the MS analyzer.