Aspects relate to systems and methods for inspirate sensing to determine a probability of an emergent physiological state. An exemplary system an inhalation sensor module configured to sense and transmit a plurality of inhalation parameters as a function of at least an inspirate, an environmental sensor module configured to sense and transmit a plurality of environmental parameters as a function of an environment, and a processor configured to generate a probability of an emergent physiological state by: inputting at least an environmental parameter and at least an inhalation parameter to a probabilistic machine learning model and generating the probability of an emergent physiological state as a function of the machine learning model.

A respiration assistance device includes a nasal respiration assisting section for supplying a gas to the nasal cavity of a living body. The nasal respiration assisting section includes: a first gas supplying portion which supplies a gas below one of the nostrils of the living body; a second gas supplying portion which supplies the gas below the other nostril of the living body; a first tube connecting portion to which a tube for supplying the gas to the first gas supplying portion is connectable; and a second tube connecting portion to which a tube for supplying the gas to the second gas supplying portion is connectable.

Disclosed herein are systems and methods for producing an illumination pattern in a gas tube of a facially-fitting device, which is used in conjunction with a capnograph. The illumination pattern is determined by at least one illumination parameter, derived at least from measured CO.sub.2 data, such that the illumination pattern is indicative of at least one breath-related/physiological parameter and/or one or more of the respiratory/physiological conditions determined/assessed based at least on the CO.sub.2 data.

A high throughput method for label-free, noncontact, noninvasive, and nondestructive detection of at least one virus infected or virus free individual from at least one tested individual is provided. The method includes collecting a sample from exhaled breath of a subject for analysis of the sample. The collecting includes the subject exhaling into at least one sampler and collecting aerosols and/or any airborne compound from the exhaled breath by passing the exhaled breath through a metamaterial membrane within the sampler. The metamaterial membrane is arranged transverse to a flow of exhaled breath through the sampler. The method further includes analyzing the sample for detection of at least one virus infected individual from at least one tested individual.

Disclosed are a disease diagnosis device and a diagnosis method thereof. The disease diagnosis device includes a pump for pumping a respiratory gas, a first pre-treatment portion connected to the pump and removing moisture and bad breath in the respiratory gas, and a volatile organic compound (VOC) detection portion connected between the first pre-treatment portion and the pump to detect VOCs in the respiratory gas.

To provide a mask capable of reducing a load of a patient while suppressing lowering of accuracy at which a subject's exhaled air is measured. A mask to be put on a subject's face includes a mask body portion demarcating an internal space in a state of covering part of the subject's face and a cup-shaped nasal cup covering a subject's nose in a state of being arranged inside the internal space, in which the nasal cup includes a first wall portion covering the subject's nose, a second wall portion arranged under the subject's nostrils, and an exhaled air discharge portion guiding an exhaled air from the subject's nose to an exhaled air sensor, and at least part of the exhaled air from the subject's nose is guided toward the exhaled air discharge portion by the second guide portion in a state where the nasal cup covers the subject's nose.

There is described a wearable respiration sensor generally having a stretchable substrate to be worn around a user's torso; and a dipole antenna having two flexible conductive elements extending in opposite directions from a center, relative to a dipole axis, and being secured to the stretchable substrate, each of the two flexible conductive elements having a proximate end near the center, a distal end away from the center, and a curved portion curving away from and back towards the dipole axis between the proximate end and the distal end, the two flexible conductive elements being in a point reflection symmetry relative to one another relative to said center in a manner that, when the stretchable substrate is stretched along the dipole axis, the curved portions of the two flexible conductive elements are flattened and the distal ends are moved away from one another.

Various embodiments of the disclosed technology present a structural foundation for volumetric flow reconstructions for expiratory modeling enabled through multi-modal imaging for pulmonology. In some embodiments, this integrated multi-modal system includes infrared (IR) imaging, thermal imaging of carbon dioxide (CO.sub.2), depth imaging (D), and visible spectrum imaging. These multiple image modalities can be integrated into flow models of exhale behaviors enable the creation of three-dimensional volume reconstructions based on visualized CO.sub.2 distributions over time, formulating a four-dimensional exhale model which can be used to estimate various pulmonological traits (e.g., breathing rate, flow rate, exhale velocity, nose/mouth distribution, tidal volume estimation, and CO.sub.2 density distributions). Various embodiments also enable the accurate acquisition of numerous pulmonary metrics that are then stored within distributed systems for respiratory data analytics and feature extraction through deep learning embodiments.

Various systems, devices, components, and methods are disclosed for measuring the concentration of an analyte, such as acetone, in a breath sample. The disclosed devices include a breath sample analysis device having a mouthpiece configured to facilitate engagement with a user's mouth to receive a breath sample. The disclosed devices also include a breath sample capture cartridge containing an interactant that extracts the analyte from a breath sample passed through the cartridge. Also disclosed are devices for routing the breath sample through the cartridge during exhalation, and for analyzing a reaction in the cartridge to measure a concentration of the analyte.

A system and method for measuring the effectiveness of a dose from an inhaler on a user is disclosed. The inhaler includes a drug container and a dosing mechanism coupled to the drug container to aerate a dose from the drug container. The dosing mechanism provides the aerated dose to the user. A sensor interface is in communication with a physiological sensor. The physiological sensor is attached to a user to sense a physiological response to the dose. Physiological data is sent to the sensor interface. A controller is coupled to the sensor interface to collect the sensed physiological data from the user corresponding to the time that the aerated dose is delivered to the user. The effectiveness of the dose may be determined from the collected data. The dose amount or frequency may be changed or the drug may be changed based on the collected data.