A ventilation monitoring system includes one or more processors configured to receive data from a sensor positioned along a breathing circuit during a mechanical ventilation procedure for a patient. The one or more processors are also configured to analyze the data to determine respective concentrations of ions at the sensor and to calculate a detected ratio of the respective concentrations of the ions at the sensor. The one or more processors are also configured to compare the detected ratio to an expected ratio to determine a condition of the patient and to output a notification to indicate the condition of the patient.

A traumatic brain injury (“TBI”) guideline system employing a patient monitoring sensor (30) and a patient monitoring device (10). In operation, the patient monitoring sensor (30) generates data for monitoring a TBI parameter of a patient (e.g., systolic blood pressure, blood oxygen saturation or carbon dioxide expiration of the patient), and the patient monitoring device (10) generates a TBI indicator derived from a comparison of the TBI parameter data to parameter guideline data associated with a potential TBI of the patient. The patient monitoring device (10) may include a patient data monitor module (17a) to monitor the TBI parameter data, and a TBI monitor module (17b) to generate the TBI indicator. The TBI indicator is informative of a TBI status of the patient (e.g., a hypotension status, a hypoxia status or a ventilation status of the patient), and/or a TBI treatment for the patient (e.g., a ventilation treatment for the patient).

The embodiments disclose a method including providing impedimetric biosensor electrodes and circuits on a substrate, providing at least two different biopolymer materials on the conductive impedimetric biosensors electrodes and circuits, applying a predetermined electrical current to the impedimetric biosensor electrodes for establishing a baseline value, providing at least one biologic sample onto the impedimetric biosensors electrodes for detection of at least one disease microorganism, measuring the electrical current after contact with the at least one biologic sample for changes in the baseline value, recording changes in the electrical current measurements, analyzing the electrical current measurements for identifying predetermined detected disease microorganisms electrical current measurements changes, and determining the concentration of a detected disease microorganism.

A gas delivery conduit adapted for fluidly connecting to a respiratory gases delivery system in a high flow therapy system, the gas delivery conduit includes a first connector adapted for connecting to the respiratory gases delivery system, a second connector adapted for connecting to a fitting of a patient interface, tubing fluidly connecting the first connector to the second connector where the first connector has a gas inlet adapted to receive the supplied respiratory gas, one of electrical contacts and temperature contacts integrated into the first connector. The gas delivery conduit further can include a sensing conduit integrated into the gas delivery conduit, where the first connector of the gas delivery conduit is adapted to allow the user to couple the first connector with the respiratory gases delivery system in a single motion.

A pump-less breath analysis device regulates the flow of breath past a nanoparticle sensor (or other semiconductor sensor) by dynamically adjusting the state or position of a valve as the user exhales into the device. The valve controls the flow of incoming breath between two flow paths: a venting path through which breath exits the device without passing by the nanoparticle sensor, and a sensing path that includes the nanoparticle sensor. In some embodiments, the valve is controlled by a processor that monitors pressure produced by the user's exhalation force. Based on these real-time pressure measurements, the processor adjusts the valve to maintain the pressure, and thus the flow rate, in the sensing path within a desired range. The processor may also use the pressure measurements to determine whether the characteristics of the user's exhalation are sufficient to generate a valid measurement.

A movable carrier auxiliary system includes a driver state detecting device and a warning device. The driver state detecting device includes a physiological state detecting module, a storage module, and an operation module. The physiological state detecting module is adapted to detect a physiological state of a driver. The storage module is disposed in a movable carrier and stores an allowable parameter corresponding to the at least one physiological state. The operation module is disposed in the movable carrier and is electrically connected to the physiological state detecting module and the storage module to detect whether the at least one physiological state of the driver exceeds the allowable parameter or not, and to correspondingly generate a detection signal. The warning device generate a warning message when the detection signal that the at least one physiological state of the driver exceeds the allowable parameter is received.

A volumetric sampling apparatus for volatile compounds comprises a structure, such as a channel structure that forms a continuous curve between the inlet port and the outlet port. A gas flow induced in the structure urges volatile compounds collected via transdermal diffusion toward the outlet port, where the volatile compounds may be collected and analyzed by a gas composition analyzer coupled to the outlet port.

Methods and systems for conditioning a gas sample for analysis and measuring, detecting, and/or determining the concentration of at least one analyte in a gas sample. Methods include a combination and/or repetition of dehumidifying and/or humidifying the gas, and/or performing a chemical reaction an analyte, and measuring, detecting, and/or determining the concentration of an analyte or an output analyte resulting from the chemical reaction. Systems to adjust the humidity of a gas sample and/or perform a chemical reaction on an analyte, and measure, detect, and/or determine the concentration of an analyte or an output analyte resulting from the chemical reaction comprise cartridges, capsules, test strips or test strip chambers and one or more sensors. Systems may further comprise a humidity exchange material to further adjust the humidity. Gas samples include exhaled breath. Analytes include nitric oxide. Output analytes include nitrogen dioxide.

Disclosed is a breath sampling device comprising a buffer tube, sensor module and breath sampling port. The buffer tube has a proximal end into which a user exhales and a distal end opposite the proximal end, the sensor module is at the distal end and used for measuring parameters of a breath exhaled by the user into the buffer tube, and the breath sampling port is disposed between the proximal end and distal end. The used exhales into the distal end and a portion of the exhaled breath can be diverted into the sampling port substantially without contacting the sensor module.

The invention relates to a breath test system that is unobtrusive in that it does not require a person subjected to the system to take any other action to breath. It comprises a sensor unit (5) configured to sense the presence or concentration of a volatile substance, present in air flowing through a predefined inlet area (4), and to generate a signal corresponding to the concentration of said substance. There is also provided an apparatus (2, 3) configured to detect the presence of a person at a position in the vicinity of said input area, and having means for registering said presence, and further configured to respond to said presence by delivering an output. This said apparatus includes a unit configured to call for immediate attention of said person, upon said registration of the presence of said person, and a unit configured to provide instructions to said person to direct an expiratory air flow towards said inlet area (4). An analyzer (10) for the determination of breath substance concentration of said person is also provided, the determination being based on said signal corresponding to the substance concentration.