Provided is a control device (20, 20a) for controlling an operation of an aerosol nebulizer system (30), said aerosol nebulizer (system 30) comprising an aerosol generator (31) for nebulizing a liquid or an aerosol source for dispensing aerosol, said control device (20), 20a comprising: a communication unit (21, 21a), configured to establish a first wireless communication connection and to perform first data transmission with the aerosol nebulizer system (30), a control unit (22, 22a), configured to evaluate a progression of identifications received via the first data transmission and received in association with aerosol nebulizer data units respectively related to a usage of the aerosol nebulizer system (30).

In examples, there is a method comprising receiving an esophageal gas sample at a nitric oxide sensor, the nitric oxide sensor generating a signal indicative of the amount of nitric oxide in the esophageal gas sample, the nitric oxide sensor outputting the signal, and, based on the signal, determining the amount of nitric oxide in the esophageal gas sample.

In examples, there is a method comprising receiving an esophageal gas sample at a nitric oxide sensor, the nitric oxide sensor generating a signal indicative of the amount of nitric oxide in the esophageal gas sample, the nitric oxide sensor outputting the signal, and, based on the signal, determining the amount of nitric oxide in the esophageal gas sample.

A device for determining measurement values describing the function of the lungs or the respiratory system of a patient includes a mouthpiece including a tube for introducing respiratory air and for sucking in air, and a gas measurement space. At least one of the following gas sensors is arranged in the gas measurement space: nitrogen monoxide sensor, carbon dioxide sensor, oxygen sensor, carbon monoxide sensor, multi-gas sensor, sensor for volatile organic compounds, alkane sensor, infrared sensor, fiber optic sensor, resistance sensor, and semiconductor sensor. The gas measurement chamber is separated by a closable opening into a first gas measurement chamber and a second gas measurement chamber, the second gas measurement chamber being closed or closable. The closable opening opens a flow path from the first gas measurement chamber into the second gas measurement chamber. A gas sensor is arranged in the second gas measurement chamber.

A device for determining measurement values describing the function of the lungs or the respiratory system of a patient includes a mouthpiece including a tube for introducing respiratory air and for sucking in air, and a gas measurement space. At least one of the following gas sensors is arranged in the gas measurement space: nitrogen monoxide sensor, carbon dioxide sensor, oxygen sensor, carbon monoxide sensor, multi-gas sensor, sensor for volatile organic compounds, alkane sensor, infrared sensor, fiber optic sensor, resistance sensor, and semiconductor sensor. The gas measurement chamber is separated by a closable opening into a first gas measurement chamber and a second gas measurement chamber, the second gas measurement chamber being closed or closable. The closable opening opens a flow path from the first gas measurement chamber into the second gas measurement chamber. A gas sensor is arranged in the second gas measurement chamber.

The present invention is an adjustment means for a mandibular advancement device. The mandibular advancement device being of the type having both intraoral and extraoral portions, including a body portion that is at the interface between the intraoral and extraoral portions and thereby is part intraoral and part extraoral. The extraoral portion includes a lower arm that is substantially straight and extends directly outwardly from the extraoral part of the body portion, and a curved upper arm that curves upwardly from the lower arm and back towards the face of a person using the device. The posterior end of the upper arm includes a pad assembly that is adapted to make contact with, and apply pressure to, the subnasal maxillary bone of the wearer. A substantial portion of the lower arm is engageable with motorised means that are encapsulated within the body portion and are adapted to engage with the lower arm and cause it to slide further out of, or slidably retract further into, the body portion.

The present invention is an adjustment means for a mandibular advancement device. The mandibular advancement device being of the type having both intraoral and extraoral portions, including a body portion that is at the interface between the intraoral and extraoral portions and thereby is part intraoral and part extraoral. The extraoral portion includes a lower arm that is substantially straight and extends directly outwardly from the extraoral part of the body portion, and a curved upper arm that curves upwardly from the lower arm and back towards the face of a person using the device. The posterior end of the upper arm includes a pad assembly that is adapted to make contact with, and apply pressure to, the subnasal maxillary bone of the wearer. A substantial portion of the lower arm is engageable with motorised means that are encapsulated within the body portion and are adapted to engage with the lower arm and cause it to slide further out of, or slidably retract further into, the body portion.

Devices and methods for monitoring physiologic parameters are described where an airway device, in one embodiment, may comprise a mouthpiece section and an opening section defining one or more airway lumens therethrough with a first sensor in fluid communication with the one or more airway lumens and a second sensor positioned upon a hand-piece for contact against a portion of the user. The first sensor may be configured to detect an airway pressure when a user inhales or exhales through the one or more airway lumens, and the second sensor may be configured to detect a physiological signal from the user. Additionally, a controller may be in communication with the first and second sensors where the controller is programmed to correlate pressure oscillations in the airway pressure with heartbeats.

Devices and methods for monitoring physiologic parameters are described where an airway device, in one embodiment, may comprise a mouthpiece section and an opening section defining one or more airway lumens therethrough with a first sensor in fluid communication with the one or more airway lumens and a second sensor positioned upon a hand-piece for contact against a portion of the user. The first sensor may be configured to detect an airway pressure when a user inhales or exhales through the one or more airway lumens, and the second sensor may be configured to detect a physiological signal from the user. Additionally, a controller may be in communication with the first and second sensors where the controller is programmed to correlate pressure oscillations in the airway pressure with heartbeats.

Apparatus is provided that includes left-nostril, right-nostril, and oral pressure sensors and oral pressure probes. A memory is configured to store left-nostril, right-nostril, and oral pressures sensed by the respective sensors, over a total period of at least 12 hours. A processor is configured to convert the left-nostril, right-nostril, and oral pressures stored in the memory to left-nostril, right-nostril, and oral pressure airflows, respectively, and calculate a series of orally-weighted laterality-indices over a respective series of sub-periods of the total period. Each of the orally-weighted laterality-indices of each of the sub-periods is indicative of a laterality index over the sub-period weighted by a normalized oral airflow over the sub-period, such that the greater the normalized oral airflow, the smaller the orally-weighted laterality-index. Each of the orally-weighted laterality-indices of each of the sub-periods reflects relative airflow through the left and the right nostrils over the sub-period. Other embodiments are also described.