A gas sampling line having a channel for conducting respiratory gases from a patient respiratory interface to a gas monitor, the gas sampling line comprising, i.a., a gas sampling tube comprised of a polyether block amide material, the polyether segments of which comprise polyethyleneoxide. Use of a tube comprised of a polyether block amide material, the polyether segments of which comprise polyethyleneoxide, for sampling of respiratory gases; and a method for sampling of respiratory gases, the method comprising conducting respiratory gases through such a tube. A gas analysis system for analysing respiratory gases, comprising a gas sampling line as defined above and a gas monitor connectable to the gas sampling line.

A portable system is disclosed for collecting a sample from exhaled breath of a subject. Drug substance in the exhaled breath are detected or determined. The sample is collected for further analysis using mass-spectroscopy. The system comprises a sampling unit and a housing arranged to hold the sampling unit, the sampling unit is adapted to collect non-volatile and volatile compounds of the at least one drug substance from the exhaled breath from the subject. The housing has at least one inlet for the subject to exhale into the housing to the sampling unit and at least one outlet for the exhaled breath to exit through.

A portable system is disclosed for collecting a sample from exhaled breath of a subject. Drug substance in the exhaled breath are detected or determined. The sample is collected for further analysis using mass-spectroscopy. The system comprises a sampling unit and a housing arranged to hold the sampling unit, the sampling unit is adapted to collect non-volatile and volatile compounds of the at least one drug substance from the exhaled breath from the subject. The housing has at least one inlet for the subject to exhale into the housing to the sampling unit and at least one outlet for the exhaled breath to exit through.

In examples, there is a method comprising receiving an esophageal gas sample at a nitric oxide sensor, the nitric oxide sensor generating a signal indicative of the amount of nitric oxide in the esophageal gas sample, the nitric oxide sensor outputting the signal, and, based on the signal, determining the amount of nitric oxide in the esophageal gas sample.

In examples, there is a method comprising receiving an esophageal gas sample at a nitric oxide sensor, the nitric oxide sensor generating a signal indicative of the amount of nitric oxide in the esophageal gas sample, the nitric oxide sensor outputting the signal, and, based on the signal, determining the amount of nitric oxide in the esophageal gas sample.

A device for determining measurement values describing the function of the lungs or the respiratory system of a patient includes a mouthpiece including a tube for introducing respiratory air and for sucking in air, and a gas measurement space. At least one of the following gas sensors is arranged in the gas measurement space: nitrogen monoxide sensor, carbon dioxide sensor, oxygen sensor, carbon monoxide sensor, multi-gas sensor, sensor for volatile organic compounds, alkane sensor, infrared sensor, fiber optic sensor, resistance sensor, and semiconductor sensor. The gas measurement chamber is separated by a closable opening into a first gas measurement chamber and a second gas measurement chamber, the second gas measurement chamber being closed or closable. The closable opening opens a flow path from the first gas measurement chamber into the second gas measurement chamber. A gas sensor is arranged in the second gas measurement chamber.

A device for determining measurement values describing the function of the lungs or the respiratory system of a patient includes a mouthpiece including a tube for introducing respiratory air and for sucking in air, and a gas measurement space. At least one of the following gas sensors is arranged in the gas measurement space: nitrogen monoxide sensor, carbon dioxide sensor, oxygen sensor, carbon monoxide sensor, multi-gas sensor, sensor for volatile organic compounds, alkane sensor, infrared sensor, fiber optic sensor, resistance sensor, and semiconductor sensor. The gas measurement chamber is separated by a closable opening into a first gas measurement chamber and a second gas measurement chamber, the second gas measurement chamber being closed or closable. The closable opening opens a flow path from the first gas measurement chamber into the second gas measurement chamber. A gas sensor is arranged in the second gas measurement chamber.

The present invention is an adjustment means for a mandibular advancement device. The mandibular advancement device being of the type having both intraoral and extraoral portions, including a body portion that is at the interface between the intraoral and extraoral portions and thereby is part intraoral and part extraoral. The extraoral portion includes a lower arm that is substantially straight and extends directly outwardly from the extraoral part of the body portion, and a curved upper arm that curves upwardly from the lower arm and back towards the face of a person using the device. The posterior end of the upper arm includes a pad assembly that is adapted to make contact with, and apply pressure to, the subnasal maxillary bone of the wearer. A substantial portion of the lower arm is engageable with motorised means that are encapsulated within the body portion and are adapted to engage with the lower arm and cause it to slide further out of, or slidably retract further into, the body portion.

The present invention is an adjustment means for a mandibular advancement device. The mandibular advancement device being of the type having both intraoral and extraoral portions, including a body portion that is at the interface between the intraoral and extraoral portions and thereby is part intraoral and part extraoral. The extraoral portion includes a lower arm that is substantially straight and extends directly outwardly from the extraoral part of the body portion, and a curved upper arm that curves upwardly from the lower arm and back towards the face of a person using the device. The posterior end of the upper arm includes a pad assembly that is adapted to make contact with, and apply pressure to, the subnasal maxillary bone of the wearer. A substantial portion of the lower arm is engageable with motorised means that are encapsulated within the body portion and are adapted to engage with the lower arm and cause it to slide further out of, or slidably retract further into, the body portion.

Devices and methods for monitoring physiologic parameters are described where an airway device, in one embodiment, may comprise a mouthpiece section and an opening section defining one or more airway lumens therethrough with a first sensor in fluid communication with the one or more airway lumens and a second sensor positioned upon a hand-piece for contact against a portion of the user. The first sensor may be configured to detect an airway pressure when a user inhales or exhales through the one or more airway lumens, and the second sensor may be configured to detect a physiological signal from the user. Additionally, a controller may be in communication with the first and second sensors where the controller is programmed to correlate pressure oscillations in the airway pressure with heartbeats.