The invention relates to a device (1, 1′) and a method for obtaining an indicator of microcirculatory condition of a patient. The device (1, 1′) comprises at least one first sensor (13) for measuring data indicative of first carbon dioxide levels, in particular tissue carbon dioxide levels, at least one second sensor (12) for measuring data indicative of second carbon dioxide levels, in particular transcutaneously measured arterial blood carbon dioxide levels, and a control unit (4) for determining a measure of microcirculation, in particular changes in tissue perfusion, preferably in septic patients, on the basis of the tissue carbon dioxide level and the transcutaneously measured arterial blood carbon dioxide level.

The invention relates to a device (1, 1′) and a method for obtaining an indicator of microcirculatory condition of a patient. The device (1, 1′) comprises at least one first sensor (13) for measuring data indicative of first carbon dioxide levels, in particular tissue carbon dioxide levels, at least one second sensor (12) for measuring data indicative of second carbon dioxide levels, in particular transcutaneously measured arterial blood carbon dioxide levels, and a control unit (4) for determining a measure of microcirculation, in particular changes in tissue perfusion, preferably in septic patients, on the basis of the tissue carbon dioxide level and the transcutaneously measured arterial blood carbon dioxide level.

The present invention relates to a peripheral oxygen saturation measurement device, the device including a light projection unit including a plurality of light sources which project pieces of light in different wavelength bands, a drive unit which drives the plurality of light sources at designated frequencies, a code modulation unit which modulates the frequencies at which the plurality of light sources are driven using at least one designated code, a light receiving unit configured to receive a light signal, which is projected from the light projection unit and passes through a user's blood vessel, convert the received light signal into an electrical signal, and outputs the electrical signal, a signal amplifying unit which amplifies the output signal of the light receiving unit, a code demodulation unit which demodulates the signal amplified by the signal amplifying unit using the same code used in the code modulation unit, and a control unit which calculates peripheral oxygen saturation using the signal projected through the light projection unit and the signal demodulated through the code demodulation unit.

The present invention relates to a peripheral oxygen saturation measurement device, the device including a light projection unit including a plurality of light sources which project pieces of light in different wavelength bands, a drive unit which drives the plurality of light sources at designated frequencies, a code modulation unit which modulates the frequencies at which the plurality of light sources are driven using at least one designated code, a light receiving unit configured to receive a light signal, which is projected from the light projection unit and passes through a user's blood vessel, convert the received light signal into an electrical signal, and outputs the electrical signal, a signal amplifying unit which amplifies the output signal of the light receiving unit, a code demodulation unit which demodulates the signal amplified by the signal amplifying unit using the same code used in the code modulation unit, and a control unit which calculates peripheral oxygen saturation using the signal projected through the light projection unit and the signal demodulated through the code demodulation unit.

The present invention provides an improved system, device, and method for determining a comprehensive state of health in real time using non-invasive patient testing. The invention characterizes disease and other states of health by simultaneously assaying both liquid and gas in a sample or samples. During metabolism, the body performs a large variety of biochemical reactions. Reaction products, reaction by-products, and breakdown products are transported by the circulatory system throughout the body. Many of these molecular products are labile and volatilize into gases from bodily liquids. In gas form, these compounds appear as volatile organic compounds (VOCs).

The present invention relates to a sampling unit, a measurement system and method for transcutaneous blood gas measurements. In particular the invention relates to a sampling unit and system adapted for rapid measuring and monitoring of blood gases in a continuous gas flow. The sampling unit is provided with an ambient air inlet and a blood gas extraction and mixing chamber wherein air is mixed with extracted blood gases. The method of continuous transcutaneous measurement of carbon dioxide in the blood utilizes a pulsed heating to minimize the detrimental effects of the heating.

The present invention relates to a sampling unit, a measurement system and method for transcutaneous blood gas measurements. In particular the invention relates to a sampling unit and system adapted for rapid measuring and monitoring of blood gases in a continuous gas flow. The sampling unit is provided with an ambient air inlet and a blood gas extraction and mixing chamber wherein air is mixed with extracted blood gases. The method of continuous transcutaneous measurement of carbon dioxide in the blood utilizes a pulsed heating to minimize the detrimental effects of the heating.

A sensor system has a low-noise sensor controller providing communications between an active-temperature-regulated optical sensor and an external monitor. A low-noise sensor controller drives optical emitters, receives resulting detected signals after attenuation by a blood perfused tissue site and communicates the detector signals to the attached signal processor. An optically-isolated controller front-end receives and digitizes the detected signals. A controller serializer transmits the digitized detector signal to the processor via a single, shielded coaxial cable.

A sensor system has a low-noise sensor controller providing communications between an active-temperature-regulated optical sensor and an external monitor. A low-noise sensor controller drives optical emitters, receives resulting detected signals after attenuation by a blood perfused tissue site and communicates the detector signals to the attached signal processor. An optically-isolated controller front-end receives and digitizes the detected signals. A controller serializer transmits the digitized detector signal to the processor via a single, shielded coaxial cable.

A sensor device includes a housing defining a cavity, an inlet to receive fluid pumped from an instrument device, an outlet to return the fluid to a fluid reservoir, and a fluid channel defined inside the cavity between the inlet and the outlet. A heat pump is mounted inside the cavity, and has a side surface thermally coupled to the fluid channel and an opposite side surface thermally coupled to a plate. The heat pump is configured to induce a temperature change. A sensor unit is aligned with an aperture in the plate and includes an optical component and a thermal component. The optical component configured to measure a vascular endothelial response from the induced temperature change.