Medical device systems include processing circuitry configured to acquire sensed cardiac signals associated with cardiac activity of a heart of a patient, and to analyze the sensed cardiac signals to determine if a noise signal is present within the cardiac signals.

Systems and methods are provided for water resistant connectors. A male connector includes a rib or a draft angle that creates a seal when engaged with a female connector. A male connector includes an overmold that includes or is made of a thermoplastic elastomer. Male or female connectors include molds that include or are made of a thermoplastic polymer, such as polypropylene. A female connector includes spring contacts that fit within individual pockets of the female connector.

A universal implantable integrated circuit medical device platform having integral and monolithic circuit traces. The platform allows for implanting into a mammalian body single and multi-functional interface devices for sensing, monitoring stimulating and/or modulating physiological conditions within the body. Microelectronic circuitry may be integrated onto the platform or may be joined as modular components to the platform.

A universal implantable integrated circuit medical device platform having integral and monolithic circuit traces. The platform allows for implanting into a mammalian body single and multi-functional interface devices for sensing, monitoring stimulating and/or modulating physiological conditions within the body. Microelectronic circuitry may be integrated onto the platform or may be joined as modular components to the platform.

A blood pressure monitor configured to removably mount to a cuff in a substantially symmetrical position with respect to a width of the cuff can include a housing defining an interior, a first port, and a second port. The first port can: secure to a first prong of the cuff when the cuff is mounted in a first orientation; receive and secure to a second prong of the cuff when the cuff is mounted in a second orientation; and enable fluid communication between the interior and at least one of a first fluid passage within the first prong and a second fluid passage within the second prong. The second port can: secure to the second prong of the cuff when the cuff is mounted in the first orientation; and receive and secure to the first prong of the cuff when the cuff is mounted in the second orientation.

A method for time-synchronizing waveforms from different patient monitors that does not require devices to have high-precision synchronized clocks or to be coupled to a triggering synchronization signal generator. Comparable signals may be obtained from different devices either by placing selected sensors from the devices in the same locations, or by filtering signals from one device to obtain a signal comparable to signals from another device. Filtering may for example transform waveforms into independent components and identify a component that matches a signal from another device. The comparable signals may then be transformed into frequency variation curves, such as time intervals between peak values, to facilitate detection of the time shift between the signals. Cross correlation of the frequency variation curves may be used to locate the precise time shift between the signals. Use of frequency variation curves may be more robust than directly comparing and correlating the original signals.

A method for time-synchronizing waveforms from different patient monitors that does not require devices to have high-precision synchronized clocks or to be coupled to a triggering synchronization signal generator. Comparable signals may be obtained from different devices either by placing selected sensors from the devices in the same locations, or by filtering signals from one device to obtain a signal comparable to signals from another device. Filtering may for example transform waveforms into independent components and identify a component that matches a signal from another device. The comparable signals may then be transformed into frequency variation curves, such as time intervals between peak values, to facilitate detection of the time shift between the signals. Cross correlation of the frequency variation curves may be used to locate the precise time shift between the signals. Use of frequency variation curves may be more robust than directly comparing and correlating the original signals.

A method and system are disclosed for use in monitoring/screening/diagnosing sleep or wake state of a subject or patient. The method generally includes monitoring the patient's activity during one or more sleep sessions comprising a plurality of intervals known as epochs. The sleep/wake state of the subject is determined during each epoch of the session using actigraphy data obtained during the monitoring session. The actigraphy data provides information about the activity of a patient during an epoch. The sleep or wake state is determined based on a ratio of the activity count during an epoch to the activity count during a preceding epoch. If the ratio is greater than a first activity threshold, then a “wake” indication may be provided by, for example, the system. Alternatively, or additionally, a “wake” indication may be determined if the activity count during the epoch is greater than a threshold.

A method and apparatus for measuring a biopotential signal together with impedance changes uses electrodes on a subject’s skin and for compensating for such impedances to increase accuracy and usability of such devices for short-and long-term monitoring of biosignals. The apparatus can include a first terminal for connection to a first electrode, a second terminal for connection to a second electrode, a first circuitry configured for measuring the biopotential signal from the first and the second terminal, a third terminal for connection to the reference skin electrode, a first variable controlled resistance load connected to the first terminal, and a second variable controlled resistance load connected to the second terminal.

A method and apparatus for measuring a biopotential signal together with impedance changes uses electrodes on a subject’s skin and for compensating for such impedances to increase accuracy and usability of such devices for short-and long-term monitoring of biosignals. The apparatus can include a first terminal for connection to a first electrode, a second terminal for connection to a second electrode, a first circuitry configured for measuring the biopotential signal from the first and the second terminal, a third terminal for connection to the reference skin electrode, a first variable controlled resistance load connected to the first terminal, and a second variable controlled resistance load connected to the second terminal.