A magnetic resonance imaging (MRI) apparatus and a method of processing an MR image are provided. The MRI apparatus includes a scanner configured to acquire a first image that is a T1-weighted image and a second image that is a fluid attenuated inversion recovery (FLAIR) image by performing an MRI scan on a brain. The MRI apparatus further includes an image processor configured to determine a white matter region in the second image based on the first image and the second image, and detect a white matter hyperintensity (WMH) region in the determined white matter region. The MRI apparatus further includes an output interface configured to display the detected WMH region and a change in the WMH region over time.

In some embodiments, apparatuses and methods are provided herein useful to receive, facilitate, and manage food ordering, especially remote, electronic food ordering. In some embodiments, a food order processing and management system includes an electronic user interface that receives a food order, a database with a plurality of food preparation facilities and capabilities associated therewith, and a central computer coupled to the database, where the central computer is configured to maintain the capabilities of the various food preparation facilities, such as the available ingredients and preparation selections in the database, receive a retrieval time for a particular food preparation facility and present the available capabilities to the user based on the updated database, and notify the food preparation facility of the details of the food order including the selected ingredients and preparation details, along with the retrieval time.

In some examples, a system may include a plurality of electrodes, electrical stimulation circuitry, and a controller. The controller may be configured to select one or more parameters of therapy to be delivered to a brain of a patient and to control the electrical stimulation circuitry to deliver the therapy to the brain of the patient based on the selected parameters and via a first one or more electrodes of the plurality of electrodes. The parameters may be defined based on a first plurality of electrical signals sensed at a plurality of different positions within the brain of the patient when electrical stimulation is not delivered at each of the positions and a second plurality of electrical signals sensed at each of the plurality of different positions within the brain of the patient in response to electrical stimulation delivered at each of the positions at a plurality of different intensities.

Embodiments may provide multimodal diagnostic systems and methods for detecting neurological disorders, such as Alzheimer's disease (AD), Parkinson's disease (PD), depression, PTSD, schizophrenia, dementia and many others. For example, a system for monitoring brain activity may comprise a plurality of sensors, each adapted to monitor a physical or physiological parameter and output a signal representing the monitored physical or physiological parameter, wherein the plurality of sensors includes at least one sensor configured to monitor a brain activity parameter, a data collection device adapted to receive the plurality of signals from the plurality of sensors and to process the signals to form digital data representing the monitored physical or physiological parameters, and a data processing device adapted to process digital data representing the monitored physical or physiological parameters to determine presence of a neurological disorder or condition.

Devices, systems, and methods for auto-retroperfusion of the cerebral venous system. In an exemplary embodiment of a catheter for controlling blood perfusion pressure of the present disclosure, the catheter comprises a body having a proximal open end, a distal end, a lumen extending between the proximal open end and the distal end, and a plurality of orifices disposed thereon, each of the orifices in fluid communication with the lumen, at least one expandable balloon, each of the at least one expandable balloons coupled with the body, having an interior that is in fluid communication with the lumen and adapted to move between an expanded configuration and a deflated configuration, and at least one sensor coupled with the distal end of the body, each of the at least one sensors adapted to gather data relating to a fluid flowing through the lumen, wherein the catheter is configured to be coupled to a flow unit for regulating the flow and pressure of a fluid.

A method for estimating a likelihood of a stroke condition of a subject, the method comprising: acquiring clinical measurement data pertaining to said subject, said clinical measurement data including at least one of image data, sound data, movement data, and tactile data; extracting from said clinical measurement data, potential stroke features according to at least one predetermined stroke assessment criterion; comparing said potential stroke features with classified sampled data acquired from a plurality of subjects, each positively diagnosed with at least one stroke condition, defining a positive stroke dataset; and determining, according to said comparing, a probability of a type of said stroke condition, and a probability of a corresponding stroke location of said stroke condition with respect to a brain location of said subject.

A processing device receives signals associated with nerve impulses that are transmitted to the visual cortex of a subject in response to one or more visual stimuli provided to at least one eye of the subject. The processing device processes the received signals and generates digital image data from the processed received signals that is representative of the visual perception, by the subject, of the one or more visual stimuli. In certain embodiments, the processing device processes digital image data that is representative of a scene to convert the digital image data to a sequence of nerve impulses, and provides the sequence of nerve impulses to the visual cortex of a subject such that the subject visually perceives the scene.

A system and method for monitoring cardiovascular and brain functions in combination with a physiological detection device, which uses a smart wearable device to detect physiological data such as heart rate and pulse pressure of a user, and transmits the physiological data to an arithmetic function. An electronic device in which a preset function and a calculation formula are built in, and the physiological data can be converted into corresponding determination parameters to monitor the possibility and risk of cardiovascular diseases and neurodegenerative diseases.

An intravascular device for placement within an animal vessel, the intravascular device being adapted to at least one of sense and stimulate activity of neural tissue located outside the vessel proximate the intravascular device.

Devices, systems and techniques are provided to facilitate chronic monitoring of biological signals. An implant device can include a set of branch portions. Each branch portion can include multiple electrodes disposed on a bottom surface and can have vias that connect the electrode to a trace on the top of the branch portion. Each branch portion can include a hole through which a connector (e.g., suture) can be pulled. The connector can also be threaded through a hole in a curved arm of an implantation tool, To implant the implant device, the implantation tool can be inserted through an incision, moved to a target location and stabilized. An end of the connector can then be pulled, which can cause the implant device to move to the target location. The implant device can then be stabilized and the implantation tool explanted.