An x-ray imaging apparatus and associated methods are provided to receive measured projection data in a primary region and measured scatter data in asymmetrical shadow regions and determine an estimated scatter in the primary region based on the measured scatter data in the shadow region(s). The asymmetric shadow regions can be controlled by adjusting the position of the beam aperture center on the readout area of the detector. Penumbra data may also be used to estimate scatter in the primary region.

A surgical frame and a radiation-mitigation system are provided. The surgical frame can be capable of reconfiguration before, during, or after surgery, and can include a main beam that can be rotated, raised/lowered, and tilted upwardly/downwardly to afford positioning and repositioning of a patient supported thereon. Furthermore, use of imaging techniques to facilitate imaging of anatomical structures of a patient before, during, and after surgery can be desirous. An emitter of such imaging techniques can be positioned under the main beam of the surgical frame. The radiation-mitigation system can serve to intercept/block and mitigate at least some of the scatter of the electromagnetic radiation from the emitter.

Provided are an image acquisition method, an imaging system, calibration equipment and a storage medium. The image acquisition method includes: acquiring a projection image formed by an imaging beam passing through a barrier array plate; acquiring scattered sampling points corresponding to the barrier posts in the projection image; interpolating a vacancy between every adjacent scattered sampling points to obtain interpolated sampling points; and acquiring a scattering distribution map corresponding to the projection image based on the scattered signals of the scattered sampling points and of the interpolated sampling points.

In an exemplary embodiment, a tomography device comprises a scanner that obtains image slices. The device additionally comprises at least one processor configured to: perform a Hermetic Transform on the image slices to obtain hermetically transformed data using; filter and perform an Inverse Hermetic Transform on the Hermetic Transform data to obtain filtered inverse Hermetic Transform data; and perform back projection and angle integration on the filtered inverse Hermetic Transform data.

An auxiliary device attachable to a mammography machine having an X-ray source and an X-ray receptor having a receptor area. The auxiliary device includes a housing having a length, width, and thickness, wherein the length and width of the housing are adapted to a length and width of the receptor area. The auxiliary device further includes one or more attachments for attaching the auxiliary device to the mammography machine, and a detector inside the housing. The detector includes a slab of semiconductor material, an electrode on a first side of the slab, and a pixelated electrode detector on the second side of the slab, and a read-out circuit bonded to the pixelated electrode detector, and the read-out circuit being configured for spectral photon counting with two or more energy bins. Methods for medical imaging are also provided.

A portable x-ray device for producing x-rays may include a housing; an exposure device enclosed by the housing to generate x-rays; a slide switch connected to the exposure device being movable between a first position and a second position; a first trigger to activate the exposure device when the slide switch is in the first position being positioned on a first side of the housing; a second trigger to activate the exposure device when the slide switch is in the second position being positioned on a second opposed side of the housing.

The invention concerns a method for processing energy spectra of radiation transmitted by an object irradiated by an ionising radiation source, in particular X-ray radiation, for medical imaging or non-destructive testing applications. The method uses a detector comprising a plurality of pixels, each pixel being capable of acquiring a spectrum of the radiation transmitted by the object. The method makes it possible, based on a plurality of detected spectra, to estimate a spectrum, referred to as the scattering spectrum, representative of radiation scattered by the object. The estimation involves taking into account a spatial model of the scattering spectrum. Each acquired spectrum is corrected taking into account the estimated scattering spectrum. The invention makes it possible to reduce the influence of the scattering, by the object, of the spectrum emitted by the source.

An x-ray imaging system includes an x-ray source configured to emit x-ray radiation towards a sample, and a primary detector configured to detect x-ray radiation from the x-ray source passing through the sample. The x-ray imaging system also includes a secondary detector configured to detect x-ray radiation from the x-ray source scattered in the sample, and imaging optics configured to guide x-ray radiation scattered in the sample onto the secondary detector.

A multimodal imaging apparatus, comprising a rotatable gantry system positioned at least partially around a patient support, a first source of radiation coupled to the rotatable gantry system, the first source of radiation configured for imaging radiation, a second source of radiation coupled to the rotatable gantry system, the second source of radiation configured for at least one of imaging radiation or therapeutic radiation, wherein the second source of radiation has an energy level more than the first source of radiation, and a second radiation detector coupled to the rotatable gantry system and positioned to receive radiation from the second source of radiation, and a processor configured to combine first measured projection data based on the radiation detected by the first detector with second measured projection data based on the radiation detected by the second detector, and reconstruct an image based on the combined data, wherein the reconstructing comprises at least one of correcting the second measured projection data using the first measured projection data, correcting the first measured projection data using the second projection data, and distinguishing different materials imaged in the combined data using the first measured projection data and the second measured projection.

Materials and methods are disclosed for screening advanced glycation end-products from mammalian ocular lens proteins to quantify early biomarkers for the diagnosis of diseases such as diabetes mellitus and to prevent related complications.