Patent classifications
C12N15/52
GLYCOLIPOPEPTIDE BIOSURFACTANTS
Surfactants based on a newly discovered class of compounds include a hydrophobic lipid oligomer covalently linked to a peptide or peptide-like chain and a carbohydrate moiety, and a serine-leucinol dipeptide linked to the lipid oligomer. Such surfactants can be used to create an oil-in-water or water-in-oil emulsion by mixing together a polar component; a non-polar component; and the surfactant. Biosurfactants of the newly discovered class can be made by isolating and culturing a microorganism which produces the biosurfactant, and then isolating the biosurfactant from the culture. A microorganism can be engineered to produce biosurfactant of this newly discovered class by expressing a set of heterologous genes involved in the biosynthesis of the biosurfactant in the microorganism.
Method of producing and processing diamines to a diamine free base using a carbonate intermediate and an engineered microorganism
Provided is a method of producing and isolating a diamine produced by microbial fermentation that minimizes undesirable salt formation to provide a lower cost process.
Method of producing and processing diamines to a diamine free base using a carbonate intermediate and an engineered microorganism
Provided is a method of producing and isolating a diamine produced by microbial fermentation that minimizes undesirable salt formation to provide a lower cost process.
L-THREONINE EXPORT PROTEIN VARIANT AND METHOD FOR PRODUCTION OF L-THREONINE USING SAME
The present disclosure relates to an L-threonine export protein variant, a microorganism including same, and a method for production of L-threonine using same.
L-THREONINE EXPORT PROTEIN VARIANT AND METHOD FOR PRODUCTION OF L-THREONINE USING SAME
The present disclosure relates to an L-threonine export protein variant, a microorganism including same, and a method for production of L-threonine using same.
MANNANASE FOR FORMULATIONS HAVING PH 5-12
A mannanase at least 85% identical to SEQ ID NO: 1, a polynucleotide encoding the mannanase, an expression construct comprising the polynucleotide, and a host cell comprising the polynucleotide or the expression construct.
MANNANASE FOR FORMULATIONS HAVING PH 5-12
A mannanase at least 85% identical to SEQ ID NO: 1, a polynucleotide encoding the mannanase, an expression construct comprising the polynucleotide, and a host cell comprising the polynucleotide or the expression construct.
SYNTHETIC PROTEIN CIRCUITS DETECTING SIGNAL TRANSDUCER ACTIVITY
Disclosed herein include methods, compositions, and kits suitable for use in detecting the activation level of a signal transducer. In some embodiments, there are provided synthetic protein circuits wherein recruitment of synthetic protein circuit components to an association location upon activation of a signal transducer generates an active effector protein. The effector protein can be configured to carry out a variety of functions when in an active state, such as, for example, inducing cell death. Methods of treating a disease or disorder characterized by aberrant signaling are provided in some embodiments.
Polypeptide Variants
The present invention relates to novel lactase variants having improved properties relative to the parent lactase, such as decreased galactose inhibition or increased galactose inhibition. The variants of the invention are suitable for production of dairy products, such as low-lactose dairy products or lactose-free dairy products. The present invention also relates to isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the lactase variants of the invention.
Polypeptide Variants
The present invention relates to novel lactase variants having improved properties relative to the parent lactase, such as decreased galactose inhibition or increased galactose inhibition. The variants of the invention are suitable for production of dairy products, such as low-lactose dairy products or lactose-free dairy products. The present invention also relates to isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the lactase variants of the invention.