A ligation device that includes a clip device including an openable arm, a connector connected to the clip device and is able to be released from the connector, a wire connected to the connector and configured to operate the clip device, and a pipe including an opening into which the wire is inserted. An inner diameter of the opening is smaller than a dimension in a diameter direction of the connector in a first state in which the connector and the clip device are connected with each other, and the inner diameter of the opening decreases towards a proximal end side of the pipe and is larger than the dimension of the connector in a second state in which the connector and the clip device are unconnected with each other.

A ligation device that includes a clip device including an openable arm, a connector connected to the clip device and is able to be released from the connector, a wire connected to the connector and configured to operate the clip device, and a pipe including an opening into which the wire is inserted. An inner diameter of the opening is smaller than a dimension in a diameter direction of the connector in a first state in which the connector and the clip device are connected with each other, and the inner diameter of the opening decreases towards a proximal end side of the pipe and is larger than the dimension of the connector in a second state in which the connector and the clip device are unconnected with each other.

Disclosed is an atrial appendage clip, including a first clip arm and a second clip arm that are symmetrically arranged; a first cavity and a second cavity are correspondingly provided in the first clip arm and the second clip arm along an axial direction thereof; a first spring and a second spring are correspondingly provided in the first cavity and the second cavity; the first spring is connected with the second clip arm via a first pull wire, and the second spring is connected with the first clip arm via a second pull wire, so as to form a closed loop structure; and as the first spring and the second spring are stretched or compressed, the first clip arm and the second clip arm are opened or closed therebetween.

Disclosed is an atrial appendage clip, including a first clip arm and a second clip arm that are symmetrically arranged; a first cavity and a second cavity are correspondingly provided in the first clip arm and the second clip arm along an axial direction thereof; a first spring and a second spring are correspondingly provided in the first cavity and the second cavity; the first spring is connected with the second clip arm via a first pull wire, and the second spring is connected with the first clip arm via a second pull wire, so as to form a closed loop structure; and as the first spring and the second spring are stretched or compressed, the first clip arm and the second clip arm are opened or closed therebetween.

The present disclosure relates to delivery devices and interventional devices configured to enable monitoring of pressure and other hemodynamic properties before, during, and/or after a cardiac procedure. A guide catheter includes a routing lumen or a routing groove for routing a sensor wire to a desired location during a cardiac procedure. A guide catheter includes one or more pressure sensors positioned to provide desired pressure measurements when the guide catheter is deploying an interventional device. An interventional device may also include one or more associated sensors for providing hemodynamic information before, during, and/or after deployment.

The present disclosure relates to delivery devices and interventional devices configured to enable monitoring of pressure and other hemodynamic properties before, during, and/or after a cardiac procedure. A guide catheter includes a routing lumen or a routing groove for routing a sensor wire to a desired location during a cardiac procedure. A guide catheter includes one or more pressure sensors positioned to provide desired pressure measurements when the guide catheter is deploying an interventional device. An interventional device may also include one or more associated sensors for providing hemodynamic information before, during, and/or after deployment.

A heart valve repair system includes a delivery sheath and an implant that includes a frame having a surface configured to contact an upstream surface of a native heart valve. First and second gripping members are coupled to the frame and each (1) includes first and second arms and (2) is configured to clamp a respective native leaflet. The implant is disposed in the sheath in a delivery state in which the frame defines a wall fully surrounding a central longitudinal axis of the implant. The distal end of the wall defines a distal opening of the frame. The distal end of the wall is disposed proximally to the entire first tissue-engaging surface of each of the gripping members and proximally to the entire second tissue-engaging surface of each of the gripping members. Other embodiments are also described.

A heart valve repair system includes a delivery sheath and an implant that includes a frame having a surface configured to contact an upstream surface of a native heart valve. First and second gripping members are coupled to the frame and each (1) includes first and second arms and (2) is configured to clamp a respective native leaflet. The implant is disposed in the sheath in a delivery state in which the frame defines a wall fully surrounding a central longitudinal axis of the implant. The distal end of the wall defines a distal opening of the frame. The distal end of the wall is disposed proximally to the entire first tissue-engaging surface of each of the gripping members and proximally to the entire second tissue-engaging surface of each of the gripping members. Other embodiments are also described.

Three-arm clamp includes: clamping assembly and releasing member connected to each other, clamping assembly includes fixed arm, and two movable arms respectively rotatably connected to fixed arm by hinge pin; the proximal end of each movable arm is provided with first sliding slot, and sliding pin is slidably arranged in first sliding slot; the proximal end of fixed arm is provided with inner cavity, and releasing member is inserted into inner cavity and connected to sliding pin; the proximal end of each movable arm is provided with elastic sheet; movable arms and fixed arm are closed by clamping, and elastic sheets are folded in inner cavity, in radial direction of fixed arm, from connecting end to free end and abut against releasing member; and releasing member is separated from movable arms, and the free end of each elastic sheet elastically abuts against inner wall of inner cavity.

A device for applying a hemostatic clip assembly includes a proximal delivery catheter having a handle assembly and an elongated catheter body defining a longitudinal axis extending distally from the handle assembly, and a distal clip assembly removably connected to a distal end of the catheter body. The distal clip assembly includes a distal clip housing, a jaw assembly and a jaw adapter yoke. The jaw assembly has a pair of jaw members fixed to the distal clip housing by a first pin oriented orthogonally relative to the longitudinal axis. The jaw adapter yoke is operatively connected to the jaw members. The proximal delivery catheter is configured to transmit linear motion along and torsion about the longitudinal axis to at least a portion of the distal clip assembly. At least one of the jaw members is configured to rotate about the first pin between an open and a closed configuration.