Systems and methods for assessment of one or more suspected conditions of an individual that include receiving collaborative identification data pertaining to features of a suspected condition and subject-specific phenomena of presentation, selecting target phenomena, receiving quantitative hypotheses for the target phenomena, defining an observation protocol comprising instructions for how the individual is to self-monitor and register observations by interaction with a portable data acquisition system, upon each occurrence of the target phenomena, directing the individual to provide the stored data upon observation of a target phenomenon during observation periods, transmitting the stored data from the portable data acquisition system to the analysis component, directing the individual to recall each observation period, completing one or more quantitative comparisons between any of the stored data, the quantitative hypotheses, and the recollection, inferring the suspected conditions, and determining a continued progress of the assessment.

Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.

A method for measuring sound from vortices in the carotid artery comprising: a first and second quality control provisions, wherein the quality control compares detected sounds to pre-determined sounds, and upon confirmation of the quality control procedures, detecting sounds generated by the heart and sounds from vortices in the carotid artery for at least 30 seconds. A method for determining stenosis of the carotid artery in a human patient consisting of a first step of placing a sensing device comprising an array and three sensing elements onto the patient, wherein a first sensing element is placed near the heart and the two remaining sensing elements are placed adjacent to the carotid arteries; the sensing elements then measure sounds from each of the three sensing elements, resulting in sound from three channels. The sound is measured in analog and modified to digital format and then each of the three channels are analyzed before a power spectral density analysis is performed. The power spectral density graph reveals peaks that are not due to noise, that are then analyzed to provide for a calculation of percent stenosis or complete occlusion of the carotid artery.

In one aspect, a sensory, motor and/or cognitive analysis device includes a casing unit structured to include a contact side conformable to a forehead region of a user; a data acquisition unit structured to include one or more sensors to detect electrophysiological signals of the user when the user makes contact with the device; a data processing unit encased within the casing unit and in communication with the data acquisition unit to amplify and digitize the detected electrophysiological signals as data, to process the data, to store the data, and to transmit the data to a remote computer system; and a power supply unit encased within the casing unit to provide electrical power, in which the device is operable to acquire physiological and/or behavioral signal data from the user used to determine a quantitative and/or qualitative information set associated with a cognitive or sensory assessment.

A spirometer comprises a housing defining a fluid flow pathway extending between a first end and a second end, a first opening along the pathway and a second opening longitudinally spaced along the pathway from the first opening. A flow chamber defining a fluid flow pathway is disposed within the housing between the first opening and the second opening, the flow chamber including an elongated resistive element along the central longitudinal axis of the flow chamber for defining a flow passage through the flow chamber between the resistive element and the inner surface of the flow chamber. The flow chamber conditions fluid flow for accurate sensing of the fluid flow over a range. A pressure sensor is disposed within the housing in fluid communication with the first opening and the second opening for sensing a pressure differential between the first opening and the second opening and producing an electric signal that corresponds with the rate of fluid flow through the housing. The described spirometer and associated software has a variety of applications in the evaluation, diagnosis, monitoring, and improvement of respiratory conditions as well as digitally-delivered respiratory rehabilitation programs and clinical trials.

Disclosed systems include a self-contained electroencephalogram (EEG) recording patch comprising a first electrode, a second electrode and wherein the first and second electrodes cooperate to measure a skin-electrode impedance, a substrate containing circuitry for generating an EEG signal from the measured skin-electrode impedance, amplifying the EEG signal, digitizing the EEG signal, and retrievably storing the EGG signal. The patch also comprises a power source and an enclosure that houses the substrate, the power source, and the first and second electrodes in a unitary package.

Disclosed embodiments may include a device, system and method for providing a low cost device that can measure refractive errors very accurately via attachment to a smart phone. A disclosed device may use ambient light or a light source in simulating the cross cylinder procedure that optometrists use by utilizing the inverse Shack-Hartman technique. The optical device may include an array of lenslets and pinholes that will force the user to effectively focus at different depths. Using an optical device, in conjunction with a smart phone, the user first changes the angle of the axis until he/she sees a cross pattern (the vertical and horizontal lines are equally spaced). The user adjusts the display, typically using the controls on the smartphone, to make the lines come together and overlap, which corresponds to bringing the view into sharp focus, thus determining the appropriate optical prescription for the user.

A skin moisture testing system comprises a PCB, a skin moisture testing system arranged on the PCB and including a Bluetooth MCU, a Bluetooth antenna impedance matching unit, a RC integral and diode rectifier unit, a sinusoidal signal unit, a first contact, a second contact, a first spring arranged around the first contact, a second spring arranged around the second contact, and a case. The case includes a housing, an upper cover, and a connecting cover. The PCB is received in the housing. The first contact and the second contact are integrally fanned with the upper cover, and the connecting cover defines a receiving space for receiving the upper cover.

There is a need for robust and portable system, and apparatus for ophthalmology. We propose use of folding apparatus for ocular purposes for the first time. Our system will have a chin-rest (or face-rest or forehead rest) that can be folded so that the ocular device could be transported in a brief-case type casing.

Disclosed herein are spirometers that can be used for assessment of pulmonary lung function. The disclosed systems, computer readable mediums and methods can be directed towards use in a variety of settings by health care professionals, clinical trial specialists, and individual users.