Aspects of the present disclosure are directed toward apparatuses, methods, and systems comprising an introducer apparatus for facilitating subcutaneous implantation of a medical device. The introducer apparatus may include a housing and an inserter configured to disengage from the second portion.

Applicators for applying an on-skin assembly to skin of a host and methods of their use and/or manufacture are provided. An applicator includes an insertion assembly configured to insert at least a portion of the on-skin assembly into the skin of the host, a housing configured to house the insertion assembly, the housing comprising an aperture through which the on-skin assembly can pass, an actuation member configured to, upon activation, cause the insertion assembly to insert at least the portion of the on-skin assembly into the skin of the host, and a sealing element configured to provide a sterile barrier and a vapor barrier between an internal environment of the housing and an external environment of the housing.

Embodiments relate to an insertion device that includes: a plunger coupled with a lock collar. The insertion device houses contents including: a striker including self-locking striker snap arm(s) where the striker is kept from firing by a striker spring captured between the plunger and the striker when the insertion device is in a cocked position; a sensor assembly; and a needle carrier that holds a piercing member, the needle carrier captured between the striker and a needle carrier spring where a self-releasing snap(s) keeps the needle carrier cocked, where the plunger prevents the self-releasing snap(s) from repositioning and releasing the needle carrier. The striker fires the needle carrier such that the self-locking striker snap arm(s) are positioned to allow the striker to snap down. The needle carrier is then retracted when the user releases the plunger and the piercing member is encapsulated within the insertion device.

A simple, disposable sensing device for sensing an analyte is housed in a single case. The sensing device can transmit sensor data to monitoring device(s). The sensing device includes: a case having a lower major wall adapted to be mounted against a patient's skin, and an upper opposing major wall; a sensor extending from the case and having a distal end sensitive to the analyte to produce an electrical signal, and a proximal end within the case having electrical contacts; a printed circuit board assembly within the case supported by one of the major walls to receive the electrical signal via the electrical contacts; and an elastomeric pad disposed in the case and biased by the other major wall to urge the proximal end of the sensor into contact with the printed circuit board assembly and maintain an electrical connection between the electrical contacts and the printed circuit board assembly.

A medical sensor device includes a sensor assembly including an underside surface for attachment against a patient's skin, a sensor portion to detect a characteristic of the patient, and sensor assembly contacts which in operation carry signals representing the detected characteristic. The device also includes a transmitter assembly removably engageable with the sensor assembly and including circuitry to take the signals from the sensor assembly contacts and to transmit readings of the detected characteristic to external equipment. The device also includes mechanical interface components on the sensor assembly and the transmitter assembly which allow the transmitter assembly to be brought into abutment with the sensor assembly at a first angular position via relative axial movement between them, and then allow a relative rotation of the assemblies with respect to one another towards a second angular position and presents axial separation of the assemblies in the second angular position.

A simple sensing device includes a case with one or more indicators to indicate levels of an analyte such as glucose. The sensing device for self-monitoring an analyte includes a single, flexible case adapted to adhere to a skin of a patient. It also includes a printed circuit board assembly inside the case. It further includes a first sensor extending from the flexible case and electrically coupled to the printed circuit board, and one or more indicators in the flexible case, where the indicator(s) are adapted to indicate whether a level of an analyte is within a normal range.

An insertion device for inserting a medical device into a living body includes: a needle portion internally defining an accommodation space configured to accommodate the medical device and configured to be inserted into a living body together with the medical device accommodated in the accommodation space; and a movable portion that is movable with respect to the needle portion in the accommodation space in a direction of insertion of the needle portion. The needle portion comprises a clamping portion configured to change a form in the accommodation space between a first form in which the clamping portion clamps the medical device accommodated in the accommodation space and a second form in which the clamping portion does not clamp the medical device accommodated in the accommodation space. The movable portion engages the clamping portion to change the form of the clamping portion from the first form to the second form.

An electrochemical sensing system includes a working electrode and a reference electrode, which can at least partially be disposed in a housing. At least a portion of the working electrode includes rhodium metal. An electrical circuit is disposed in the housing and configured to be electronically coupled to the electrodes. The electrical circuit is operative to: (a) bias the working electrode at a voltage of less than about 0.4 V, and (b) measure a current corresponding to the concentration of the target analyte. A communications module is electrically coupled to the electrical circuit and configured to display a concentration of the target analyte, and/or communicate data between the electrical circuit and an external device. The electrodes are movable between a first configuration in which the electrodes are substantially disposed inside the housing, and a second configuration in which at least a portion of the electrodes is disposed outside the housing.

Systems and methods for transcutaneously implanting medical devices, such as in vivo analyte sensors, are provided. The systems and methods involve the use of introducers or inserters made of shape memory alloy (SMA) materials which are transitionable from one operative state or configuration to another operative state or configuration, wherein the transition from state to state enables the transcutaneous implantation and/or transcutaneous explantation of the medical device.

A tissue sensing device and a method for placing the device. The device including a first electrically conductive needle; a non-conductive sheath receiving the first needle therein and allowing exposure of a portion the first needle at a distal end thereof; a second electrically conductive needle; and electronics coupled to the first and second needle, the electronics providing for sensing of capacitance between the first and second needles so as to provide an indication of a tissue in which the exposed portion of the first needle is located.