A package has a plurality of seamless compartments coupled together. A different one of the plurality compartments each includes a different respective one of a plurality of respective void spaces and a different respective one of a plurality of respective void space delimiting surfaces. A different one of a plurality of fill entries each forms a fluent entry into a different respective compartment's void space. At least one fill entry of said plurality is in an elastomeric portion of said package, and the at least one fill entry has a largest cross sectional area which is equal to or less than 25% of a largest cross sectional area of the compartment having the respective void space for which the fill entry forms the fluent entry. Each void space delimiting surface follows an outline of a separate 3D pill shape.

A tray system for filling pills into a blister pack is provided, as well as a corresponding method. The system includes a mounting tray to support the blister pack, rows of lights, with each light adapted to illuminate the pill-chambers of the blister pack; a depositing plate placed over the mounting tray and includes depositing-plate rows with pairs of pill-drop surface and a pill-hole, each pill-hole faces a corresponding pill-chamber; a sliding tray placed over the depositing plate which includes sliding-tray rows with opened cavities, and is slidable over the depositing plate from a pill-drop position to a chamber-filling position. Moving the sliding tray from the pill-drop position to the chamber-filling position pushes the pills from the pill-drop surfaces to the pill-chambers. The depositing plate material allows lights emissions to pass through the pill-drop surfaces while hiding the pills in the pill-chambers of the blister pack.

Disclosed is an elongate form medicament carrier carrying multiple distinct medicament dose portions. The said carrier has a first end, a second end, a central portion extending across the width of the elongate form medicament carrier, a first portion between the first end and the central portion and containing a medicament active, or a mixture of medicament actives, and a second portion between the second end and the central portion and containing a medicament active, or a mixture of medicament actives. The central portion of the carrier has a first end region, a unified length and a second end region, the unified length has a trailing end connecting to the first portion of the carrier via the first end region and connecting to the second portion of the carrier via the second end region, and the unified length has a leading end connecting to a loop of the central portion of the carrier.

A storage container for a storage and dispensing station for drugs is provided. The storage container includes a housing surrounding a holding space which housing has a guide section and a bottom surface, the guide section defining a guide space and having a vertical guide recess, which does not penetrate the housing, and the bottom surface having a dispensing opening. The storage container includes a separating device having at least one channel for holding at least one drug portion and comprises a retaining element having a retaining section and having a guide element, which is arranged in the guide recess, the vertical guide recess and the guide element interacting in such a way that the retaining element is arranged for height adjustment in the guide recess by means of the guide element and rotational motion of the retaining means is prevented.

A multi-compartment package for dispensing plural items is disclosed. The package includes plural individual sealed compartment units which are releasably secured to each other. Each compartment unit includes a flanged base from which a chamber depends. The chamber serves to hold an item to be dispensed and is surrounded by a flange. A closure member, in the form of a respective portion of a frangible cover sheet, is adhesively secured to the flange of each compartment unit. Each compartment unit includes at least one foldable tab in a corner of its flange, which can be folded down to enable the closure member to be removed from the compartment unit after the compartment unit is separated from other compartment units of the package.

The present disclosure enables apparatus and methods for tracking medications and/or product units via smart-packaging concepts. Embodiments include sensors that monitor the state of a blister-card package having an unpatterned lidding film by measuring the impedance of each dispensing region of the lidding film that defines a portion of a blister. In some embodiments, the impedance is measured via a plurality of contact points arranged on opposite sides of each dispensing region, where the contact points are resistively or capacitively coupled with the lidding film. In some embodiments, the impedance map of a measurement region on the blister card is derived via electrical impedance tomography or electrical resistance tomography, where the measurement region includes a plurality of dispensing regions.

A modular smart packaging case comprising reversibly attachable electronics and detection modules is disclosed. The detection module includes a sensor array for monitoring the state of a blister pack containing a plurality of product units. The electronics module contains the high-value electronics required to read the sensors of the array, process the sensor output, and enable communications to and from the case. The electronics module and detection module are operatively coupled via a universal interface that enables the same electronics module to operate with a plurality of detection modules of different configurations. In some embodiments, the electronics module operatively couples with multiple detection modules.

In various aspects, the present disclosure pertains to thermoformed webs that comprise polymer films having one or more thermoformed cavities contained therein, the polymer films comprising a polymer blend of amorphous polyethylene terephthalate (APET) and a copolyester that comprises (a) dicarboxylic acid residues (e.g., dicarboxylic acid residues that comprise terephthalic acid residues and, optionally, one or more additional dicarboxylic acid residues) and (b) diol residues (e.g., diol residues comprising ethylene glycol residues and, optionally, one or more additional diol monomer residues). Other aspects of the disclosure pertain to methods of forming such thermoformed webs, packaged products comprising such thermoformed webs, and methods of recycling such thermoformed webs.

Provided are methods of producing a batch of 1,2,3,6-tetrapivaloyl-D-galactofuranoside; 5-azido-5-deoxy-1,2,3,6-tetrapivaloyl-D-galactofuranoside; intermediate grade migalastat hydrochloride; and/or migalastat hydrochloride. Also provided are methods of determining the purity of a batch of 1,2,3,6-tetrapivaloyl-D-galactofuranoside; 5-azido-5-deoxy-1,2,3,6-tetrapivaloyl-D-galactofuranoside; intermediate grade migalastat hydrochloride; and/or migalastat hydrochloride. Also provided are methods of distributing a batch of 1,2,3,6-tetrapivaloyl-D-galactofuranoside; 5-azido-5-deoxy-1,2,3,6-tetrapivaloyl-D-galactofuranoside; intermediate grade migalastat hydrochloride; and/or migalastat hydrochloride. Also provided are methods of assessing suitability of migalastat hydrochloride for medical use.

Packaging for a pharmaceutical product and a method of validating pharmaceuticals is disclosed. The packaging comprising a cavity; and validation circuitry comprising: a sensor adapted to output a signal in response to detecting a vapour in the cavity; and a detection circuit adapted to output an indication when the signal indicates a predefined vapour signature.