Disclosed in the present disclosure is a composition for improving skin damage caused by fine dust, which contains an Aureobasidium pullulans strain; a lysate thereof; a culture thereof; or an extract of the strain, the lysate or the culture as an active ingredient, and the composition has an effect of promoting the expression of keratinocyte differentiation markers and granular layer tight junction markers, thereby enhancing the skin barrier function and having skin-moisturizing, anti-aging and wrinkle-suppressing effects, and, thus, has an excellent effect in terms of improving skin damage caused by fine dust.

The present invention provides a composition for treating atopic dermatitis, the composition containing, as an active ingredient, a butanol fraction of an S. fusiforme extract.

The present disclosure provides a pharmaceutical composition comprising a first pharmaceutically active portion comprising one or more cannabinoids extracted from Cannabis plant material; a second pharmaceutically active portion comprising glutathione extracted from Cannabis plant material and optionally one or more excipients; wherein the molar ratio of the second pharmaceutically active portion to the first pharmaceutically active portion is at least 0.5:1. The present disclosure also provides a method of manufacturing a pharmaceutical composition comprising the steps of: extracting a first fraction containing one or more cannabinoids from a Cannabis plant material using a polar solvent; extracting a second fraction containing from the glutathione from the same Cannabis plant material using water; and drying and combining the first fraction and the second fraction to form the pharmaceutical composition.

The invention generally relates to a liquid topical pharmaceutical composition used in treating various skin wounds. The composition is characterized by strong moisture absorption and retention capabilities and being able to quickly seal the wound. The composition can resist oxidation, effectively inhibit bacteria and sterilization, protect germinal cells from further damage, eliminate wound swelling and promote wound healing. The pharmaceutical composition can be widely used in the treatment of burn, skin abrasion, laceration, infectious skin ulcer and wound exposure, save dressing and be used in a convenient and highly effective way.

The present invention discloses a mangosteen pericarp extract and process for its preparation thereof. The mangosteen pericarp extract containing α-mangostin and γ-mangostin which obtains from preparation steps comprising fragmentation, organic solvent soaking, aqueous solution, or acidic solution soaking, concentration, spray drying and grinding steps from the rind of the mangosteen. The present invention has advantages of simple preparation process to address efficiency issue, no need to have heating under reflux in extraction steps and the solvents which used are friendly to human body and environment. The mangosteen pericarp hydrophilic extract (α-Xones Aqua Choice) inhibits intracellular melanin production, and cellular tyrosinase activity. Mangosteen pericarp hydrophilic extract could be used as a cosmic composition for skin while, or even prevention of hyperpigmentation, as well as could be developed into a candidate drug composition for therapy of hyperpigmentation.

This invention relates to a pharmaceutical preparation for the treatment of compromised tissue such as skin wounds and ulcers in humans and animals and a method of preparation. This is a multifunctional natural matrix meant for the treatment of compromised tissues which also relates to the anti-cancer transdermal patch for melanoma therapy. Further, the invention comprises for the treatment of Alzheimer's, and multiple sclerosis also. The composition consists of water-solubilized nano-sized formulation of non-aqueous solvent extract of phyto-pharmaceuticals in herbal, animal or synthetic biocompatible gel or on matrix coated or both. The composition is used as a topical device for the treatment of compromised tissues in its preferred embodiment.

The present disclosure relates to an external-use skin preparation composition containing an extract of a fermented product of Red yeast rice. More particularly, it relates to an external-use skin preparation composition capable of providing excellent antioxidant and anti-aging effects by containing, as an active ingredient, an extract of a fermented product of Red yeast rice, which is obtained by further fermenting Red yeast rice, red rice fermented with Monascus purpureus, with yeast.

Stable liquid formulations dominant in cannabidiol (CBD) can be manufactured by a sequential process of purification to create a formulation that does not crystallize under a variety of storage and use conditions, and without the use of potentially harmful additives. For example, the formulation may be used in vaporization devices (i.e., electronic cigarettes) that typically require formulations to remain in a non-crystalline, non-solid, or non-partially solid state. The liquid formulations dominant in CBD may further contain other phytocannabinoids, including, but not limited to, tetrahydrocannabinol (THC), cannabigerol (CBG), cannabichromene (CBC), cannabinol (CBN), and cannabidivarin (CBDV) in higher concentrations than unrefined and refined cannabis extracts obtained via existing methods.

A unit dosage of an oral composition of an extract of Withania somnifera is disclosed. The extract of Withania somnifera includes total withanolides. The total withanolides includes withanolide glycosides and withanolide aglycones. The extract of Withania somnifera includes about 32% to about 38% by weight of the withanolide glycosides. Methods of preparing the extract of Withania somnifera are disclosed. Methods of treatment by administering the extract of Withania somnifera are disclosed.

The present invention relates to a method of increasing a measure of a production trait in a non-ruminant animal by administering a red seaweed of Asparagopsis species to the animal.