Patent classifications
A61K2236/35
Selective extraction method for natural substances
An extraction method for nonpolar natural substances includes: a step of conducting extraction of natural raw materials to prepare a first liquid extract; a step of mixing the first liquid extract with a phase separation composition containing a lipophilic solubilizer and water, and conducting a second extraction; and a step of isolating the supernatant of the phase-separated solution to obtain non-polar natural substances.
Optimizing volatile entourages in dry flowering plant mixtures
Novel plant products customized to provide a desired, consistent and stable Entourage of Interest (EOI) and processes for making and using the same are provided.
Optimizing volatile entourages in dry flowering plant mixtures
Novel plant products customized to provide a desired, consistent and stable Entourage of Interest (EOI) and processes for making and using the same are provided.
ORAL COMPOSITIONS OF PLANTS THROUGH A DOUBLE EXTRACTION SYSTEM AND METHODS OF MAKING THE SAME
Provided is a process, including: extracting one or more hydrophobic active ingredients of a plant material using a first extraction solvent; and transferring the one or more hydrophobic active ingredients from the first extractant solution filtrate to a carrier solvent; encapsulating the one or more hydrophobic active ingredients in one or more nanoparticles; dispersing the one or more nanoparticles in an aqueous suspension; and adding the second eluant from the plant material to the aqueous suspension.
Thin film oxidation of crystallized cannabis products
Crystallized cannabis extract having a purple color is made by first providing cannabis having a detectable amounts of tetrahydrocannabinolic acid (THCA) as well as secondary components including terpenes. Pentane or other solvent is added to the cannabis material to dissolve the secondary components. The cannabis material is enclosed in a filter basket, or a rosin press filter bag, having an average pore diameter of 25 microns. The centrifuge spins the filter bag or filter basket to separate the THCA from the cannabis material and thereby yielding a primary product that is a concentrated cannabis material having at least 95% THCA and a secondary product (high terpene extract) having combined THCA and secondary components including terpenes. The concentrated cannabis material is distilled in a wiped film evaporator or a short path evaporator to oxidize the concentrated cannabis material and yield a super concentrated cannabis material having at least 98% THC.
METHOD FOR PRODUCING EXTRACT COMPOSITION
In an aspect, the present disclosure provides a method for producing an extract composition by which polyphenols such as apigenin and/or essential oil components such as spiro-ether can be efficiently extracted from harvested herbaceous plants.
An aspect of the present disclosure is directed to a method for producing an extract composition, including processes (1) and (2) below: (1) applying an oxidative stress to a harvested herbaceous plant and preserving it; and (2) obtaining an extract from the herbaceous plant that has undergone the process (1).
COMPOSITION FOR PROMOTING HAIR GROWTH AND/OR INHIBITING HAIR LOSS
The present application relates to a composition including a herb extract and/or an effective compound as an active ingredient for promoting hair growth and/or preventing, alleviating, or treating hair loss.
SOLVENTS, METHODS, AND SYSTEMS FOR ISOLATING CANNABINOIDS FROM PLANTS EXTRACTS OR FROM SYNTHETIC PATHWAYS
The present invention provides improved solvents, methods, and systems for isolating purified cannabinoids from various sources. It has been found that C.sub.9 to C.sub.11 non-aromatic hydrocarbon solvents, and especially n-decane, work surprisingly well for crystallization of cannabinoids such as cannabidiol. Some variations provide a method of isolating cannabinoids from a cannabinoid-containing solution, comprising contacting the solution with a C.sub.9-C.sub.11 non-aromatic hydrocarbon solvent (e.g., n-decane) at a first temperature, to generate a mixture; cooling the mixture to precipitate cannabinoids; and isolating the precipitated cannabinoids. Other variations provide a method of isolating cannabinoids from a cannabinoid-containing solution, comprising contacting the solution with a C.sub.9-C.sub.11 non-aromatic hydrocarbon solvent (e.g., n-decane) at a first temperature below the solvent boiling point, to generate a mixture; subjecting the mixture to a second temperature that causes vaporization of the solvent, to precipitate at least some of the cannabinoids; and isolating the precipitated cannabinoids.
PROCESSES AND SYSTEMS FOR CONVERTING CANNABINOIDS INTO CANNABINOID DERIVATIVES AND ISOLATING THE SAME
Some variations provide a process of converting a cannabinoid into a purified cannabinoid derivative, comprising: providing a starting composition comprising a cannabinoid; providing a C.sub.9-C.sub.11 non-aromatic hydrocarbon solvent; introducing the starting composition and the solvent to a conversion reactor; chemically converting some, but not all, of the cannabinoid to a cannabinoid derivative, generating a reaction mixture containing unreacted cannabinoid; conveying the reaction mixture to a crystallization unit; cooling the reaction mixture to precipitate unreacted cannabinoid out of the reaction mixture, thereby generating a mother liquor containing the cannabinoid derivative; and isolating and recovering the cannabinoid derivative from the mother liquor. Systems configured to carry out the disclosed processes are also provided. This invention offers a large-scale solution to economically convert CBD to D9-THC, among many other example. The principles of the invention may be applied to the conversion of various cannabinoids and terpenes into derivative products.
PROCESSES FOR CONVERTING CANNABINOIDS INTO CANNABINOID DERIVATIVES AND RECOVERING THE SAME
Some variations provide a process of converting a cannabinoid into a purified cannabinoid derivative, comprising: providing a starting composition comprising a cannabinoid; providing a C.sub.9-C.sub.11 non-aromatic hydrocarbon solvent; introducing the starting composition and the solvent to a conversion reactor; chemically converting some, but not all, of the cannabinoid to a cannabinoid derivative, generating a reaction mixture containing unreacted cannabinoid; conveying the reaction mixture to a crystallization unit; cooling the reaction mixture to precipitate unreacted cannabinoid out of the reaction mixture, thereby generating a mother liquor containing the cannabinoid derivative; and isolating and recovering the cannabinoid derivative from the mother liquor. Systems configured to carry out the disclosed processes are also provided. This invention offers a large-scale solution to economically convert CBD to D9-THC, among many other example. The principles of the invention may be applied to the conversion of various cannabinoids and terpenes into derivative products.