A61L15/22

FIBRINOGEN COMPRISING FORMULATION AND USES THEREOF
20230190993 · 2023-06-22 ·

The invention relates to compositions comprised of albumin and clottable proteins including fibrinogen and to use thereof e.g., for treating bleeding. In particular, the compositions are comprised of albumin and one or more clottable proteins, wherein the albumin and the one or more clottable proteins are present at a total concentration of at least 90% by total protein weight, wherein the clottable protein fibronectin is present at an amount of less than about 0.5% by total protein weight or is absent, and wherein the weight ratio of the albumin to the clottable protein fibrinogen is at least 1:15, respectively.

ANTIMICROBIAL DRESSING
20230190989 · 2023-06-22 ·

Provided is an antimicrobial dressing, which includes: a first cover member having a plurality of pores formed therein and contacting a wound; an antimicrobial membrane that is made by accumulating nanofibers containing a water-soluble polymer that is dissolved in an exudate secreted from the wound, a water-insoluble polymer, and an antimicrobial substance released due to dissolution of the water-soluble polymer, the antimicrobial membrane being laminated on the first cover member and having a plurality of pores formed therein; and a second cover member laminated on the antimicrobial membrane and having a plurality of pores formed therein and exposed to an external air.

Method for producing water-absorbent polymer particles with improved properties
09840598 · 2017-12-12 · ·

The present invention relates to a process for producing water-absorbing polymer particles having an improved profile of properties, comprising thermal surface postcrosslinking in the presence of a salt of a polyvalent metal cation and a complexing anion and subsequent aftertreatment, the aftertreatment comprising coating with a salt of a polyvalent metal cation and a non-complexing anion, and remoisturization with further drying.

Method for producing water-absorbent polymer particles with improved properties
09840598 · 2017-12-12 · ·

The present invention relates to a process for producing water-absorbing polymer particles having an improved profile of properties, comprising thermal surface postcrosslinking in the presence of a salt of a polyvalent metal cation and a complexing anion and subsequent aftertreatment, the aftertreatment comprising coating with a salt of a polyvalent metal cation and a non-complexing anion, and remoisturization with further drying.

Methods and devices for skin closure
11679034 · 2023-06-20 · ·

A wound closure device and a method of its use are disclosed. The wound closure device includes a wound closure strip, the wound closure strip including a wound-facing side and a top side, the wound-facing side comprises an adhesive applied over at least a portion of the wound facing side of the wound closure strip and a non-symmetric, two-part release liner assembly detachably adhered to the adhesive, the release liner assembly including a first section and a second section with the second section including a wound closure strip-free portion forming a tab. In an alternate embodiment, the device is multi-segmented and the wound closure strip may be coextensive with the release liner assembly.

Methods and devices for skin closure
11679034 · 2023-06-20 · ·

A wound closure device and a method of its use are disclosed. The wound closure device includes a wound closure strip, the wound closure strip including a wound-facing side and a top side, the wound-facing side comprises an adhesive applied over at least a portion of the wound facing side of the wound closure strip and a non-symmetric, two-part release liner assembly detachably adhered to the adhesive, the release liner assembly including a first section and a second section with the second section including a wound closure strip-free portion forming a tab. In an alternate embodiment, the device is multi-segmented and the wound closure strip may be coextensive with the release liner assembly.

POLYMER MATERIALS

Polyurethane material for indicating pH at a locus, preferably as indication of presence of microbes, comprising a polyurethane network having immobilised therein one or more hydrophilic copolymers, the or each said copolymer comprising:

hydrophilic monomer; and
indicating monomer, which provides an indication in response to a change in hydrophilic state of said hydrophilic monomer and/or copolymer;
characterised in that the or each copolymer further comprises one or a plurality of ionisable groups or moieties or polymerisable monomers having one or more characteristic pKa values in the range 5 to 10 and which are responsive to pH at the locus in the range pH 5 to pH 10
and in that hydrophilic state of hydrophilic copolymer is dependent on ionisation of said ionisable groups, moieties or monomers; kit and device comprising the material and process for preparation thereof; and use in detecting or sensing microbes or pH.

Freeze-dried composition

The invention relates to freeze-dried compositions comprising a) at least one polymer based on polyacrylic acids and salts thereof, b) at least one natural polymer, c) optionally at least one further polymer which differs from a) and b) and d) optionally one or more active compounds and/or auxiliary substances. The invention furthermore relates to a process for the preparation of such freeze-dried compositions, the combination of such freeze-dried compositions in kit-of-parts arrangements together with aqueous solutions and the use of the freeze-dried compositions and of the kit-of-parts combinations for cosmetic and pharmaceutical use, in particular for use as a cosmetic mask or as a wound covering and for the preparation of pharmaceutical agents for treatment of dermal wounds, such as, in particular, chronic wounds, ulcus cruris or decubitus.

FLUID-ABSORBENT ARTICLE

The present invention relates to a fluid-absorbent article, comprising a fluid-absorbent core, comprising from 0 to 90% by weight fibrous material and from 10 to 100% by weight water-absorbent polymer particles having a mean sphericity (SPHT) from 0.8 to 0.95, based on the sum of water-absorbent polymer particles and fibrous material;

and an acquisition-distribution layer between having a three dimensional apertured structure having a femal side (5) and a male side (6), wherein the femal side presents a multiplicity of openings extending in the form of through holes in the direction of a lower surface of the same structure being the male side, wherein the quantity of the water absorbent polymer particles within the fluid absorbent core is at least 3 g.

Soft and Durable Nonwoven Web

A nonwoven web that contains a plurality of fibers formed from a polyolefm composition is provided. The polyolefin composition contains a rigid propylene polymer that has a relatively high melting temperature and modulus of elasticity, which can provide good strength and durability to the nonwoven web. The polyolefm composition also contains a ductile propylene polymer that has a relatively high melt flow index, which can help achieve relatively fine fibers that minimize the stiffness of the web. In addition to a rigid and ductile polymer, the polyolefin composition also contains a slip additive (e.g., fatty acid derivative). Among other things, such an additive can even further enhance the overall softness of the composition.