The device of the present invention includes a dual chamber gas exchanger that is configured for increased flexibility and scalability for many clinical applications. The dual chamber oxygenator can be configured and used in various applications, such as in a heart-lung machine for cardiopulmonary support during cardiothoracic surgery, in an extracorporeal membrane oxygenation (ECMO) circuitry, as a respiratory assist device for patients with lung failure, and the like. The dual chamber gas exchanger features two sweep gas flow paths and two gas exchange membrane bundles enclosed in a housing structure with various blood flow distribution and gas distribution mechanisms. The gas exchanger includes an outer housing, an intermediate housing, two gas exchange fiber bundles, a blood inlet, a blood outlet, two gas inlets, two gas outlets, two gas distribution chambers and an optional heat exchanger.

The invention relates to an extracorporeal blood treatment machine, such as a dialysis machine, comprising leakage detection as well as to a method of detecting leakages in the dialysis fluid circuit of a dialysis machine, wherein at least part of the dialysis fluid system to be monitored in terms of leakage is accommodated in a hermetically sealed housing and the housing is or can be ventilated in a controlled manner, and wherein a parameter, such as the air humidity of the air flowing into the housing is compared to a corresponding parameter, preferably air humidity of the air flowing out of the housing.

The present invention relates to devices, systems, and methods for controlling the concentration of potassium in dialysate in a closed loop potassium control system. The devices, systems, and methods can be compatible with any dialysis system including sorbent-based dialysis systems, single pass dialysis systems, or other multi-pass dialysis systems. The systems can use closed loop potassium control over potassium concentration in the dialysate to reduce the probability of patient arrhythmias. The potassium concentration can be controlled and personalized to a patient using certain predetermined patient parameters. Related systems, algorithms, and control systems are contemplated for optimizing the potassium concentration in the dialysate.

The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.

A method to determine a type of blood circuit attached to an extracorporeal blood treatment console including: pumping a liquid through a blood passage of the blood circuit, sensing a first pressure in: the blood passage while the passage is closed and pumping stopped, pumping an additional amount of the liquid into the blood passage while the blood passage is and remains closed and thereafter sensing a second pressure, and determine a dimensional characteristic of a fluid passage in the blood passage based on the additional amount of the liquid and the second pressure.

This invention relates to dialysis systems and methods. In some implementations, a method includes applying vacuum pressure to a device of a dialysis system, and then determining, based on a detected fluid level or measured pressure, whether the device is functioning properly.

A blood purification system that is capable of notifying any changes in the patient's condition on the basis of noninvasive vital sings of the patient that are observed during the blood purification treatment. An external information-processing apparatus includes an external input device into which a vital sign detected by a detecting device is inputtable in real time; a checking device capable of checking whether or not the vital sign inputted in real time into the external input device satisfies a predetermined condition; and an external output device capable of outputting, if it is determined by the checking device that the vital sign satisfies the predetermined condition, a result of the checking or checked information including the vital sign leading to the result of the checking to a blood purification apparatus. The checked information outputted from the external output device is displayable on a display included in the blood purification apparatus.

According to some embodiments, a system may treat blood outside the body of a patient. The system may include at least one toxin removal system configured to process blood from at least two places on the patient's body at a rate, for example, of at least 0.5 liters per minute. The system may be configured to raise the pH level of the patient's blood by introducing a fluid at rate of at least 9 liters per hour.

The invention is about a next-generation blood pump that provides pulsatile blood flow, and has been developed for cardiopulmonary by-pass devices used for maintaining extracorporeal blood circulation during heart surgeries and the supportive devices of circulation system. This device is technically a sort of synchronous power-assisted motor employing direct driver technology. The mentioned blood pump contains a rotor rotating on a magnetic bearing without a shaft and through the helical wings placed into the rotor it provides pulsatile blood supply adequate for the body requirement synchronous with the ECG signals received from the patients. It provides a patient safer and controlled pulsatile blood flow while running at high efficiency.

An embodiment includes a cardioplegia delivery system having a console, controller, and disposables. The system aides the perfusionist in cardioplegia delivery to the patient during Cardiopulmonary Bypass Surgery. The console, in conjunction with the disposables, combines blood from the heart-lung machine and crystalloid from the IV-bag in a specified ratio and then adds in a drug (arrest agent and/or additive). The electro-mechanical console incorporates a blood/crystalloid pump, temperature controllable water circulation system, pressure and temperature monitors, a sensor interface with the disposables, an arrest agent pump, an additive pump and ultra-sonic air detection sensors. The system monitors and controls the blood-crystalloid ratio, drug concentration, flow rate, pressure, temperature, and delivery route of the cardioplegia solution delivered to the patient. The system is a software-controlled system with a graphical user interface controller. The controller is utilized to initiate/stop cardioplegia delivery, monitor delivery parameters and view/save relevant case information and data.