The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a catheter flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.

A surgical drain device includes an adhesion matrix of biodegradable polymer material and a plurality of drain tubes attached to the matrix. The device is implanted within a surgical wound to treat the presence of seromas, for example, and is used to promote drainage, tissue adhesion, and wound closure. The drain tubes converge into a common collection tube that leads wound fluid outside the body under gravity feed or negative pressure applied to the collection tube. The matrix contains an array of apertures that allow tissue contact across the device. The device also can include a coating of surgical adhesive and a tissue anchoring system of hooks or barbs. The device can be used with a negative pressure system to further improve the drainage band can also be used with a wound dressing. The device and systems containing the device are particularly useful to promote the healing of surgical wounds from abdominal surgery.

A medical device is disclosed, which is capable of treating lymphedema and reducing a reoccurrence rate after treatment. The medical device includes a tube member that includes a first end portion connected to a first body lumen L and a second end portion connected to a second body lumen P and a pressure-feeding unit that pressure-feeds a body fluid in the first body lumen to the second body lumen.

The present invention relates to a method of implanting a blood clot removal device in a patient's body, by cutting the skin of the patient's body, dissecting an area of the patient's vascular system, placing the blot clot removal device at the dissected area, and connecting a blood flow passageway of the blood clot removal device to the patient's vascular system to allow circulation of the patient's blood through the blood flow passageway.

A filtering device for removing particles from a bodily fluid of a patient is disclosed. The device is implantable in the patient's body and comprises a tube forming a main fluid passageway for bodily fluid, through which the bodily fluid passes when the tube is implanted, wherein the tube is sized and adapted to be fluidly connected to the bodily fluid. The device further comprises a filter connected to the tube, and a filter cleaning device for cleaning the filter.

A method of securing a connecting tube for use in an implantable device for implantation in human or mammal patient, wherein the tube is adapted to move patient fluid or hydraulic treatment fluid from one part of the patient, via the at least one connecting tube to another part of the patient, the connecting tube having a distal end adapted to be located in an organ of the human or mammal patient for drainage of a patient fluid or in a reservoir for movement av hydraulic treatment fluid, from a treatment area of the human or mammal patient into the organ.

A surgical drain device includes an adhesion matrix of biodegradable polymer material and a plurality of drain tubes attached to the matrix. The device is implanted within a surgical wound to treat the presence of seromas, for example, and is used to promote drainage, tissue adhesion, and wound closure. The drain tubes converge into a common collection tube that leads wound fluid outside the body under gravity feed or negative pressure applied to the collection tube. The matrix contains an array of apertures that allow tissue contact across the device. The device also can include a coating of surgical adhesive and a tissue anchoring system of hooks or barbs. The device can be used with a negative pressure system to further improve the drainage band can also be used with a wound dressing. The device and systems containing the device are particularly useful to promote the healing of surgical wounds from abdominal surgery.

An innovative medical device that permits rapid, minimally invasive restoration of blood flow across a vascular blockage. A system allowing for lysis or removal of said blockage. Said device creates a temporary bypass using longitudinal structure configured for insertion into the blood vessel and adapted to deliver a side hole to a target area. The side hole defines a distal first segment and a proximal second segment with a lumen to allow blood flow therethrough to the distal end hole. In an alternate embodiment, a slidable outer sheath can cover the side hole to permit reversal of blood flow from the distal end hole to a proximal end hole located outside a patient's body by means of an aspiration controller. Alternate embodiments include an optional anchoring balloon, a macerating stent or wires, perforations for fluid delivery, and an backflow valve.

The present invention relates to a method of implanting a blood clot removal device in a patient's body, by cutting the skin of the patient's body, dissecting an area of the patient's vascular system, placing the blot clot removal device at the dissected area, and connecting a blood flow passageway of the blood clot removal device to the patient's vascular system to allow circulation of the patient's blood through the blood flow passageway.

A drainage device for holding an incision in an abscess of a subject open to allow drainage of fluid out of the abscess includes an elongate body and an extension member extending laterally from the elongate body. The elongate body is configured for insertion into the abscess. The extension member is configured to retain at least a portion of the elongate body in the abscess. The elongate body facilitates drainage of fluid out of the abscess.